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Healthy Volunteer

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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 81-90 of 841 for cardiovascular

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  1. ABSORB III Randomized Controlled Trial (RCT)

    Rochester, MN

  2. An Efficacy, Safety and Tolerability Study of Ixmyelocel-T Administered via Transendocardial Catheter-based Injections to Subjects with Heart Failure Due to Ischemic Dilated Cardiomyopathy (IDCM)

    Scottsdale/Phoenix, AZ

  3. A Randomized Study to Evaluate the Effect of Rapamycin in Improving Cardiac Function in Older Adults with Heart Failure

    Rochester, MN

  4. Vascular Boot Warming Program After Acute Deep Vein Thrombosis (DVT) ± Pulmonary Embolism (PE)

  5. A Dose Titration Study to Assess the Effects of SAR407899 in Patients With Microvascular Angina and/or Persistent Stable Angina Despite Angiographically Successful Elective PCI

    Rochester, MN

  6. A Study for the Continued Access of the Micra Transcatheter Pacing System

    Rochester, MN

  7. Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial

    Rochester, MN

  8. A Study to Determine the Benefits of a Dedicated Athlete Training Program to Reduce the Effects of Aging

    Scottsdale/Phoenix, AZ

  9. A Study to Evaluate the Effectiveness and Safety of Vutrisiran in Patients with Transthyretin Amyloidosis with Cardiomyopathy (ATTR Amyloidosis with Cardiomyopathy

    Rochester, MN

  10. Respiratory Muscle Contribution to Blood Pressure During Exercise

    Rochester, MN

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