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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 13 for congenital heart disease

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  • Study status: Open/Status Unknown
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  1. Autologous Induced Pluripotent Stem Cells of Cardiac Lineage Delivered Into Heart Muscle for Congenital Heart Disease

    Rochester, MN

  2. Invasive Hemodynamic Cardiopulmonary Exercise Testing for Assessment of Patients With Congenital Heart Disease

    Rochester, MN

  3. Registry for Mayo Clinic Adult Congenital Heart Disease Control Population

    Rochester, MN

  4. A Study to Evaluate NT-proBNP Levels in the Prediction of Intrapartum and Postpartum Events in Adult Congenital Heart Disease Patients

    Rochester, MN

  5. A Study to Evaluate Aortic Dilatation in Patients with Conotruncal Abnormalities

    Rochester, MN

  6. CMRI in CHD

    Rochester, MN

  7. Hypoplastic Left Heart Syndrome: Validating Functional Parameters and Novel Echocardiographic Imaging Strategies for Evaluation of Functionally Single Right Ventricular Performance using Previously Recorded Studies

    Rochester, MN

  8. A Study to Assess the Role of Biomarkers in Risk Stratification in Adults with Congenital Heart Disease

    Rochester, MN

  9. Exercise during Heart Cath in CHD Patients

    Rochester, MN

  10. A Study to Evaluate Pregnancy in Adults with Congenital Heart Disease

    Rochester, MN

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