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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 82 for joint replacement

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  1. A Study to Compare the Effectiveness of Adductor Canal Pain Catheters Following Total Knee Arthroplasty

    Jacksonville, FL

  2. A Study to Compare the Outcome of Primary Anatomic Shoulder Arthroplasty Using the Stryker ReUnion System with Implantation of Either a Peg or Keel Glenoid Construction.

    Rochester, MN

  3. Using Ice Around Postoperative Total Knee Incisions – Does This Make Sense?

  4. Treatment of Thumb Carpometacarpal (CMC) Arthritis Using Stablyx® CMC Arthroplasty System

    Rochester, MN

  5. A Study to Analyze Surgical Outcomes and Predictors of Treatment for Hip Diseases

    Rochester, MN

  6. A Study of Giving Celecoxib and Dexamethasone with Manipulation Under Anesthesia to Treat Postoperative Stiffness after Total Knee Replacement Surgery

    Rochester, MN

  7. Reverse Total Shoulder Arthroplasty versus Nonoperative Treatment of 3 & 4-Part Proximal Humerus Fractures

    Rochester, MN

  8. THA Lumbar Plexus Verses Periarticular

    Rochester, MN

  9. Survivorship of Attune Primary Total Knee Prosthesis

    Scottsdale/Phoenix, AZ

  10. Peripheral Nerve Blocks vs Periarticular Local Anesthetic Injection for TKA

    Rochester, MN

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