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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 51-60 of 183 for lung disease

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  1. A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. A Study To Evaluate the Effect of Canakinumab or Pembrolizumab Given as Monotherapy or in Combination as Neo-adjuvant Treatment for Subjects With Early Stages NSCLC

  3. A Study of the Safety and Effectiveness of HBI-8000 with Nivolumab to Treat Melanoma, Renal Cell Carcinoma and Non-Small Cell Lung Cancer

  4. Myositis Interstitial Lung Disease Nintedanib Trial

    Scottsdale/Phoenix, AZ

  5. A Study of a Multicomponent Intervention Aimed at Decreasing Perception of Dyspnea in Participants with Lung Disease Who are Obese

    Rochester, MN

  6. Home-based Health Management of Chronic Obstructive Lung Disease (COPD) Patients

    Rochester, MN

  7. Evaluation of CRS-207 With Pembrolizumab in Previously Treated MPM

    Rochester, MN

  8. Atezolizumab Immunotherapy in Patients With Advanced NSCLC (AJCC 7th Edition)

  9. Safety Study of Nivolumab With Nab-Paclitaxel Plus or Minus Gemcitabine in Pancreatic Cancer, Nab-Paclitaxel / Carboplatin in Stage IIIB/IV Non-Small Cell Lung Cancer or Nab-Paclitaxel in Recurrent Metastatic Breast Cancer

    Scottsdale/Phoenix, AZ

  10. M6620 First in Human Study

    Scottsdale/Phoenix, AZ, Rochester, MN

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