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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 103 for spine

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  1. A Study to Evaluate Post-surgical Outcomes Using the Early Recovery After Surgery (ERAS) Protocol for Posterior Cervical Decompression and Fusion

  2. Safety and Effectiveness Study of the Precision SCS System Adapted for High-Rate Spinal Cord Stimulation

    Rochester, MN

  3. A Study to Evaluate the Treatment of Lumbar Spinal Stenosis (LSS) with the MILD Procedure

    Rochester, MN

  4. A Pivotal Study of the Premia Spine TOPS™ System

    Rochester, MN

  5. Safety of Spine Radiofrequency Procedures

    Rochester, MN

  6. The MiDAS ENCORE Study

    Rochester, MN

  7. A Study to Use a Patient Monitoring Application that Monitors Physiological Data, Psychosocial Data, and Responses to Survey Questions in Patients Undergoing Cranial or Spinal Surgery

    Rochester, MN

  8. Use of Tamsulosin to Reduce the Incidence and Duration of Postoperative Urinary Retention Following Spine Surgery

    Rochester, MN

  9. Epidural and Dorsal Root Stimulation in Humans with Spinal Cord Injury

    Rochester, MN

  10. Reducing Smoke Exposure in Children Facing Surgery

    Rochester, MN

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