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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 87 for

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  1. Edwards Cardioband™ Tricuspid Valve Reconstruction System Early Feasibility Study

    Rochester, MN

  2. A Study to Improve Cardiovascular Health Among African Americans within Faith Communities

    Rochester, MN

  3. A Study of Long-Term Outcomes of Cardiac Resynchronization Therapy Recipients with Congestive Heart Failure

    Rochester, MN

  4. A Study to Evaluate NT-proBNP Levels in the Prediction of Intrapartum and Postpartum Events in Adult Congenital Heart Disease Patients

    Rochester, MN

  5. A Study to Evaluate Sex and Age Differences in Ehlers Danlos Syndrome Patients

    Jacksonville, FL

  6. A Study to Evaluate Long-term Outcomes of Alcohol Septal Ablation for Hypertrophic Cardiomyopathy

    Rochester, MN

  7. A Study to Identify Late-Occurring Complications in Childhood Cancer Survivors

    Rochester, MN

  8. A Study to Evaluate Potential Myocardial Injury in Patients with Cardiac Implantable Electronic Devices Undergoing Defibrillation Threshold Testing

    Rochester, MN

  9. Identification of Novel Genetic Variants and Biomarkers of Disease Progression in Arrhythmogenic Cardiomyopathy

    Rochester, MN

  10. Is Our Microbiome a Predictor of Cardiac Risk

    Rochester, MN

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