Featured conditions Brain tumor, breast cancer, colon cancer, congenital heart disease, heart arrhythmia. See more conditions.
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(for at least one location)
Rochester, MN
Describes the nature of a clinical study. Types include:
This study will focus on demonstrating the benefits of Photon Counting Detector CT Scan (PCD-CT) for clinical indications and findings are expected to benefit the diagnosis and characterization of Coronary Artery Disease (CAD) and myocardial perfusion defects.
Specific Aim:
In patients, measure the clinical impact of cardiac PCD-CT on patient diagnosis and management
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Open for enrollment
The primary purpose of this study is to understand the effect of educating patients and encouraging shared decision making on rates of CT scanning in head injured patients by using an already developed app and observing the effect on the health care provider
The purpose of this study is to assess whether our not the percentage of pulmonary related vascular structures (PRVS) determined by the quantitative CT (Q-CT) tool CALIPER is a novel measure that can be used for the early detection of pulmonary vascular remodeling in patients with SSc. pulmonary related vascular structures
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Scottsdale/Phoenix, AZ, Rochester, MN
The purpose of this study is to analyze the effect of parity, menopause and reproductive lifespan on kidney structure and function.
The purpose of this study is to determine the tradeoffs between CT image quality and patient radiation dose in a way that moves beyond current simple models (e.g. standard deviation and CTDIvol) by investigating the relationships between task-based metrics of image quality, observer performance, patient size, and patient dose.
The purpose of this study is to examine the ability of PCD-CT to (1) display subtle fractures of the wrist using the system’s increased spatial resolution compared to conventional wrist CT and MR; and (2) evaluate the ability of PCD-CT with virtual non-calcium images to identify bone marrow edema at acute fracture sites.
The first objective of this pilot research protocol is to evaluate the quality of PET from the SIGNA PET/MR system and to compare the quantitative accuracy of PET images from the PET/MR system to PET images from a standard PET/CT system. The second objective of this pilot research protocol is to compare the image quality from MRI images acquired on the SIGNA PET/MR to clinical MR images acquired on a standard 3.0T MRI system.
Scottsdale/Phoenix, AZ, Jacksonville, FL
The purpose of this study is to generate an additional series (reconstruction) of the low contrast dose CT exam utilizing an AI model (general adversarial network (GAN)) to simulate high contrast on CT exams.
The purpose of this study is to determine the lowest radiation dose that allows interpretation of chest CT scan.
Our group developed a novel chest CT technology with reduced radiation exposure and procedure duration. This is a new dose optimization and efficiency technology and a tin filter, which greatly reduce the radiation dose compared to a standard chest CT. The procedure is fast and can be performed without sedation. We therefore aim to validate this promising technology as an alternative clinical monitoring tool against current standard-of-care with CXR.
We hypothesize that clinical studies to investigate the role of individual proteins in kidney stone pathogenesis have likely been confounded by an unknown variety of underlying renal pathologies. Therefore, we propose to examine urinary protein crystallization inhibitors in patient populations that have been carefully phenotyped relative to renal stone precursor lesions by direct endoscopic visualization. In collaboration with Project #1, our second major goal is to use these accurately phenotyped patients in order to adapt modern dual-energy CT technology to develop a reliable noninvasive technique to accurately and noninvasively determine stone composition and visualize the earliest kidney stone precursor lesions. Our long-term goal is to improve CT technology so that it can be used to allow large-scale clinical protocols of accurately phenotyped, hence, homogeneous, patient populations. In a subset we will sample sterile stone, dental plaque, blood and urine samples for detailed microbiome analysis in order to determine the contribution of micro organisms to stone pathogensis.