Clinical Trials

The purpose of this study is to model the relationship between corneal swelling and cell density and determine how this relationship differs by contact lens type.

The purpose of this study is to compare patient-reported visual disability before and after endothelial keratoplasty in patients with Fuchs endothelial corneal dystrophy by comparing scores of the previously designed and validated Visual Function and Corneal Health Status (V-FUCHS) questionnaire. Patient-reported disability will be related to the optical properties of the cornea measured by non-contact imaging methods.

The objectives of this study are to determine if the 1-year graft success rate following DMEK performed with corneas from donors without diabetes is superior to the graft success rate with cornea donors with diabetes, to determine if the 1-year central endothelial cell loss (ECL) following DMEK performed with corneas from donors without diabetes is superior to the central ECL when corneas from donors with diabetes are used, nd to explore the relationship of severity of diabetes in the donor, as measured by eye bank-determined diabetes risk categorization scores, post-mortem hemoglobin A1c (HbA1c), and skin advanced glycation endproducts (AGE) and ...