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Low-dose CT Enterography for Pediatric Crohn’s Disease Diagnosis and Staging
Rochester, MN
The study will estimate observer performance for Low-dose CT enterography ( LD-CTE) for detection of ileal inflammation due to Crohn’s disease. It will also determine if an LD-CTE technique using multi-step kV selection and automatic exposure control can routinely acquire volumetric datasets at radiation doses similar to or less than annual background radiation levels. Furthermore, the study will determine if LD-CTE with or without ileocolonoscopy is better than validated patient symptom scores (using the Short Pediatric Crohn’s Disease Activity Index, short PDAI) in identifying patients with moderate to severe ileocolic Crohn’s disease who may benefit from treatment with biologic agents.
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A Study of the Patency Capsule and Radiologic Tests in Diagnostic Management of Patients with Suspected or Known Intestinal Strictures
Scottsdale/Phoenix, AZ
The purpose of our research study is to identify the usefulness and safety of patency capsule (PC) and compare with radiology tests such as CT enterography or MR enterography in patients with intestinal obstruction.
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A Study to Identify Biomarkers of Intestinal Fibrosis in Small Bowel Crohn's Disease
Rochester, MN
The purpose of this study is to evaluate if specific blood, stool and MRI tests can tell the difference between bowel wall inflammation without scarring and bowel wall inflammation with scarring that can cause bowel blockages requiring surgery.