Clinical Trials

The primary objective of this study is to create common data elements collected at all centers participating in this collaborative allowing for direct data comparison amongst participating centers. Secondary objectives will compare how Pediatric Epilepsy Centers evaluate surgery candidates in order to inform future studies to compare and potentially standardize the process.

The purpose of this study is to measure the space and time characteristics of inflammatory mediator release in response to induced epileptiform activity in ASD-resistant patients.

The purpose if this study  to combine state of the art cerebral signal processing techniques and localization methods with intracranial electrode recordings to investigate the interaction of local hippocampal and neocortical networks with distributed brain activity.

This research study will investigate a new recording electrode that will record brain activity during surgery. This electrode is being tested for efficacy, and may eventually replace the current electrodes used for this purpose. The goal is to record brain activity in a region of the brain that is already being removed to treat epilepsy.

The purpose of this study is to advance our understanding of the connectivity, causal role, and dynamic modulation of inter-areal communication in the human brain by recording electrocorticographic (ECoG) and stereoencephalographic (SEEG) brain signals during visual, auditory and sensory-motor tasks in patients awaiting invasive brain surgery with a particular focus on cortical networks engaged in perception of speech, language, and music.

This study is designed to use new MRI techniques to better understand and treat seizure disorders

The primary purpose of this study is to understand how epilepsy patients think about neuromodulation in relation to concepts of neuroexceptionalism and the self.

The purpose of this study is to understand how electrical stimulation of the brain can modulate and suppress interictal epileptiform activity as a step on the path to developing new therapies for epilepsy.

The purpose of this study is to determine the changes to visual fields and to neuropsychological assessments after laser ablation procedures  for temporal lobe epilepsy.