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Thyroid Autoimmune Dysfunction Due to Immune Checkpoint Inhibitors
Rochester, MN
The primary objective is to characterize the immune cell phenotypes in thyroid fine needle aspirates (FNA) and the peripheral blood of patients with ICI-induced thyroid dysfunction using flow cytometry. Control patients will be those with thyroid nodules as well as autoimmune thyroid disease, with and without exposure to ICI.
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A Study of Biomarkers to Distinguish Benign from Cancerous Thyroid Tumors
Rochester, MN
The purpose of this study is to evaluate microRNA biomarkers in the blood and fine-needle aspirate biopsies of thyroid nodules to determine their usefullness in pre-operative diagnosis, in particular to distinguish benign from cancerous thyroid nodules.
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A Study of the Impact of the Terminology Used to Identify Papillary Thyroid Cancer on the Treatment Options Chosen by Patients
Rochester, MN
The purpose of this study is to explore how using different terms (with or without the word cancer) to identify papillary thyroid cancer might affect the decisions patients would make about treatment.
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Endoscopic Ultrasound Guided Fine Needle Biopsy (EUS-FNB-SC) Using a Novel Fork Needle
Jacksonville, FL
This is a clinical trial to compare two needles used in biopsy techniques to acquire tissue from pancreatic cancer. The hypothesis is that the tissue yield, as measured by tumor DNA and cellular material is superior for Flexible Needle Biopsy (FNB) compared with conventional Fine Needle Aspiration (FNA). Specifically, FNB will increase the proportion of cases in which sufficient DNA is obtained to allow genomic profiling and whole exome sequencing.
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Clinical Evaluation of ASP Health's Automated ROSE System for Bronchoscopic Applications
Rochester, MN
The purpose of this study is to compare cytology slides (bronchoscopically derived fine needle aspiration samples of lymph nodes at the time of rapid intraprocedural on site evaluation) created with the ASP Health's specimen preparation system to slides made by existing conventional methods.
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Adequate Selection of Patients for Thyroid Biopsy: Evaluation of a Shared Decision Making Conversation Tool
Eau Claire, WI; Rochester, MN
The purpose of this study is to field test and update an existing conversation aid prototype designed to support shared decision making in the diagnosis and treatment of thyroid cancer, and to conduct a pilot randomized multi-center trial to test the refined conversation aid.
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A Study to Evaluate the Patient Experience Regarding Image-Guided Percutaneous Breast Biopsy
Jacksonville, FL
The purpose of this study is to to better understand the concerns of patients prior to a breast biopsy so that we may improve our practice and ultimately enhance overall patient experience.
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Whole Exome Sequencing and Other Emerging Technologies of Endoscopic Ultrasound Cytopathology
No Locations
The purpose of this research study is to gather information on the feasibility of performing novel molecular analysis on Endoscopic Ultrasound acquired cytologic material and to assess molecular changes in cytology samples to see if that may aid treatment decision planning for future patients.
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A Study to Evaluate the Diagnostic Potential of a Lateral Flow Assay to Detect QSOX1 Peptide in Patients With or At Risk for Pancreatic Cancer
Scottsdale/Phoenix, AZ
The purpose of this study is to evaluate the lateral flow assay (LFA) to be used in conjunction with imaging and existing biomarkers in diagnosed or at-risk-for pancreatic cancer patients.
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A Study of Disease Risk Caused by Tumor Particles Getting into the Blood from Endoscopic Ultrasound Guided Fine Needle Aspiration
No Locations
The purpose of this study is to assess the risk for cancer spread caused by the leaking of tumor particles into the blood from the biopsy procedure endoscopic ultrasound guided fine needle aspiration.
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A Study to Assess the Utility of Cell Count and Differential of Aspirated Fluid in the Diagnosis of Native Vertebral Osteomyelitis
Rochester, MN
The purpose of this study is to assess the utility of cell count and differential from aspirated fluid obtained via CT guided needle aspiration biopsy of vertebral bone and intervertebral disc space in the diagnosis of native vertebral osteomyelitis (NVO).