Clinical Trials

This study is investigating the usefulness of using functional magnetic resonance imaging (fMRI) to monitor brain activation during deep brain stimulation for Parkinson's Disease. The study may determine the relationship between patterns of brain activation and therapeutic outcome and/or side effects.

The purpose of this study is to study the brain response to different wavelengths of light. 

The objectives of this study are to identify the unique individual neuro-hormonal footprint of volumetric, caloric, and hedonic stimulation along the distinct stages of food intake regulation, to categorize the hormone(s) and brain area(s) that predominate in each stage of food intake regulation, and to discover the unique neuro-hormonal footprint which may predict subsequent caloric intake.

The objective of this study is to compare the central neural circuitry with fMRI (7T) in 30 asymptomatic healthy controls, 30 constipated patients without DD, and 30 constipated patients with DD at rest (functional connectivity analysis), during rectal distention to desire to defecate and urgency, and during evacuation. 

The dual purposes of this study are to determine whether the increased performance of the Compact 3T scanner produces higher quality data than a traditional 3T and a 7T scanner using three of the most commonly employed tasks in current clinical practice, and to determine which of these three scanner platforms provides the highest quality resting state fMRI data primarily assessing the default mode network.

The purpose of this study is to to use functional imaging to study the mechanisms of anterior thalamic nucleus (ANT) Deep Brain Stimulation (DBS).

The purpose of this study is to use functional imaging to study the mechanisms of the anterior nucleus of the thalamus (ANT) deep brain stimulation (DBS).

The purpose of this pilot project is to investigate the relationship between localized brain stiffness values and functional brain activity in response to external stimuli (visual/motor).

Our current study proposes to investigate the effect of motor and or visual stimulus on the stiffness of the motor and visual cortex using a novel compact 3T MRI system having a high gradient slew rate. We plan to leverage the unique capability of the compact 3T system to be able to obtain functional images at a higher temporal resolution in comparison to the earlier studies which used a time scale ...

The purpose of this study is to develop a functional MRI memory task for clinical presurgical mapping.

The purpose of this study is to create a new Magnetic resonance imaging (MRI) technique with true contrast to the background reference points in functional MR images of individual patients. Functional MRI has been widely used in staging, grading and treatment response monitoring of glioblastoma.  MRI has great soft tissue and tumor tissue contrast and can assist in outlining the target. It has proven able to offer functional information such as cell density, permeability of the micro-blood vessels, and the oxygen level of the tumor.

The purpose of this study is to evaluate the initial safety and effectiveness of Microburst VNS stimulation in subjects with refractory epilepsy.