Clinical Trials

The purposes of this study are to compare the functional connectivity in adolescent patients with Postural Orthostatic Tachycardia Syndrome (POTS) both with and without chronic pain, to those with chronic pain alone, to that of healthy controls; to evaluate whether there is a change in functional connectivity following participation in an intensive rehabilitation-oriented program previously demonstrated to have excellent outcomes with regard to functional recovery and symptom control; and to correlate outcomes using standardized symptom and function rating scales to imaging findings.

The primary purpose of this study is to determine if a 3-week interdisciplinary chronic pain self-management program is effective in improving 1) patient-reported measures of pain, function, quality of life mood and sleep; 2) physical capacity; 3) performance as measured by change in activity counts; and 4) sleep efficiency as measured by actigraphy.  Activity and patient reported outcomes as well as measures of performance will all be collected in patients before during and after participation in the 3-week interdisciplinray pain program and subsequently analyzed to determine how much each of these improve over the course of treatment and ...