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A Safety, Methodological and Exploratory Biomarkers Study to Slow Disease Progression
Jacksonville, FL
The purpose of this study is to determine safety of plasma infusion in APOE 44 patients.
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A Study to Evaluate sPD-L1 Clearance in Patients Undergoing Plasma Exchange Therapy
Rochester, MN
The purpose of this study is to establish the clearance rate of sPD-L1 in patients undergoing plasma exchange, and to establish the kinetics of sPD-L1 regeneration in vivo.
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A Study of Short-term Survival in Subjects With Acute-on-chronic Liver Failure After Plasma Exchange With Human Serum Albumin 5%
Rochester, MN
The purpose of this study is to evaluate the effects of plasma exchange using human serum albumin 5% (PE-A 5%) in acute-on-chronic liver failure (ACLF) subjects.
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A Study to Evaluate the Effectiveness and Safety Study of Imlifidase in Treatment of Antibody-Mediated Rejection in Kidney Transplant Patients
Rochester, MN
The purpose of this study is to investigate how efficiently the study medication imlifidase reduces the amount of donor specific antibodies (DSA) in comparison with plasma exchange (PE) therapy, in patients who have an active antibody mediated rejection (AMR) after recently been kidney transplanted. The purpose is also to investigate and compare safety for these two treatments. 20 patients will be treated with imlifidase and 10 with PE.
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A Study to Evaluate Radiation Therapy, Plasma Exchange, and Immunotherapy in Melanoma
Rochester, MN
The purpose of this study is to determine the kinetics of sPD-L1 removal and regeneration by plasma exchange in patients with melanoma.