Clinical Trials

The purpose of this study is to test new technology and health coaching aimed to help people with COPD become more physically active in their daily lives.

The main objectives of this study are to determine the difference in change from baseline in Six Minute Walk Distance (6MWD) when pulmonary rehabilitation (PR) is added to stable underlying nintedanib therapy in patients with idiopathic pulmonary fibrosis (IPF), to determine the difference in change in Quality of Life (QoL) when pulmonary rehabilitation (PR) is added to stable underlying nintedanib therapy in patients with idiopathic pulmonary fibrosis (IPF), and to determine if there is an enduring effect in 6MWD, QoL and lung function from pulmonary rehabilitation (PR) when pulmonary rehabilitation (PR) is added to stable underlying nintedanib therapy in patients with idiopathic pulmonary ...

While pulmonary rehabilitation provides benefits to people with COPD, only 1.5% have access to pulmonary rehabilitation each year. The main barriers are related to travel and transportation. This protocol will evaluate the effect of a home-based rehabilitation system on quality of life and steps. The system allows for monitoring by a health care system. A health coach will review the data and provide coaching to facilitate behavioral change and self-efficacy. Patients will be randomized to 1 of 2 groups.

The aim of this study is to evaluate the effects of a home-based program with health coaching of dyspnea and exercieses in subjects with pulmonary arterial hypertension (PAH).

Pulmonary rehabiltation has been shown to be an effective treatment for patients with chronic obstructive pulmonary disease, however there is currently a paucity of evidence to extrapolate this informaiton with patients with pulmonary arterial hypertension (PAH). In addition, there are no options outside of center-based pulmonary rehabilitation which have been proposed as an effective treatment option for patients with PAH.

Frailty is a condition characterized by slowness, weakness, low physical activity, wasting, and exhaustion. Frailty increases the risk for adverse outcomes following transplant such as increased length of stay in the hospital, mortality, or graft function. No interventions for frailty are known for patients with renal disease, but exercise programs like pulmonary rehabilitation have been effective in improving frailty in patients with other diseases, such as lung disease. The goal of this study is to test whether exercise will also improve frailty among patients who are waiting for a kidney transplant and who are considered frail or pre-frail.

Cardiopulmonary rehabilitation (CP rehab) with an exercise component is important in the care from many people with heart or lung disease. Measuring the benefits of CP rehab (i.e., measuring ‘how well CP rehab works’) depends upon having tests or ‘tools’ that can very well detect positive changes in physical and clinical function. One such tool is maximal cardiopulmonary exercise testing (CPET). This is the gold standard for measuring exercise capacity. However, maximal CPET is expensive, has extensive set-up and space requirements, needs direct medical supervision, and involves interpretive complexity; these factors have limited the widespread use of maximal ...

The purpose of this study is to assess the effect-size of a novel combined home-based telemonitored pulmonary rehabilitation and telephonic health coaching program on two co-primary endpoints: 1) patient-reported quality of life as assessed by the COPD Assessment Test (CAT) and 2) physical activity (PA) as measured by steps per day.

The purpose of this study is to assess the effect-size of a novel combined home-based telemonitored pulmonary rehabilitation and telephonic health coaching program on two co-primary endpoints: 1) patient-reported quality of life as assessed by the Chronic Respiratory Questionnaire (CRQ) and 2) physical activity (PA) as measured by steps per day.