-
A Study of the Biological System of Allergic Fungal Sinusitis Mucin
Jacksonville, FL
The purpose of this study is to describe the proteome of mucus in patients without chronic rhinosinusitis (nCRS) with an emphasis on cytokines and bone morphogenic proteins present (BMPs), to describe the proteome of mucus in patients with chronic rhinosinusitis without polyps (CRSsNP) with an emphasis on cytokines and BMPs present, to describe the proteome of mucus in patients with allergic fungal sinusitis (AFRS) with an emphasis on cytokines and BMPs present, and to identify BMPs differentially elevated in patients with AFRS compared to patients with nCRS or CRS.
-
-
Otorhinolaryngology Normal, Tumor Tissue, Saliva, Stool, and Blood Bank
Rochester, MN
The purpose of this study is to obtain tissue, blood, saliva, and stool specimens and informed consent from ENT patients in order to build a freezer archive of samples to support ongoing and future developmental studies.
-
A Study to Evaluate the Effect of Medical Intervention on Sinonasal Inflammation in Patients with Chronic Sinusitis, Nasal Polyps and Positive Sinus Culture
Jacksonville, FL; Scottsdale/Phoenix, AZ
The purpose of this study is to compare change in SNOT-22 score in patients who received medication therapy such as oral antibiotics, topical antibiotics, oral corticosteroids, topical corticosteroids, leukotriene receptor antagonist, and interleukin 5 receptor antagonist following endoscopic sinus surgery versus control in patient with chronic sinusitis with nasal polyps and a positive culture.
-
Determining Prevention of Nasal Polyp Recurrence in AERD Patients Using Aspirin
Rochester, MN
The purpose of this study is to investigate the mechanism through which aspirin works for the prevention of nasal polyp recurrence in AERD patients, while comparing two aspirin doses: 325 mg once-daily or 650 mg twice daily dose of aspirin.
-
Image Guidance Navigation Provides Objective Feedback That Can Be Used to Evaluate Surgical Trainees and Consultants
Rochester, MN
Trudi will give us the data points to address residents and consultants skill level and areas of weakness during endoscopic sinus surgeries. (ESS)
-
Outcomes of Positive Pressure Therapy for Obstructive Sleep Apnea Following Endoscopic Sinus Surgery
Scottsdale/Phoenix, AZ; Rochester, MN
The purpose of this study is to:
-
Evaluate if there are detrimental effects of restarting CPAP therapy on POD #0-1 in patients undergoing ESS compared to normal controls undergoing ESS without OSA.
-
Determine if there a difference in perception of pain and post-operative analgesia requirement in OSA patients restarting CPAP on POD #0-1 compared to non-OSA patients.
-
Determine if there are predictive factors for OSA patients undergoing ESS who require an overnight hospitalization after surgery.
-
Validate the nocturnal Rhinoconjuctivitis Quality ...