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A Study of Vagal Nerve Stimulation and Glucose Metabolism
Rochester, MN
The purpose of this study is to determine how common bariatric surgical procedures alter carbohydrate metabolism by examining the effect of vagal nerve stimulation on insulin secretion and action.
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Vagal Nerve Stimulation for Post-COVID Fatigue
Rochester, MN
The purpose of this study is to evaluate the impact of vagal nerve stimulation on symptom burden, neuroinflammatory change, and blood markers of inflammation in patients with post COVID syndrome who have fatigue and headache.
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Pivotal Study of VNS During Rehab After Stroke (VNS-REHAB)
Jacksonville, FL
This is a pivotal phase study of up to 120 subjects and 15 clinical sites. All subjects are implanted with the Vivistim System® and then randomized to either study treatment or active-control treatment. The randomization will be stratified by age (<30, >30) and baseline FMA UE (20 to <35; >35 to 50). Study treatment is vagus nerve stimulation (VNS) delivered during rehabilitation. Active control treatment is rehabilitation (standard-of-care treatment) with only a minimal amount of VNS at the start of each session intended to support blinding.
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A Study of Non-invasive Vagus Nerve Stimulation for the Prevention of Migraines
Scottsdale/Phoenix, AZ
The purpose of the study is to investigate if the use of gammaCore Sapphire™ device reduces the number of migraines preventatively.
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Peripheral Nerve Stimulation Therapy for Atrial Fibrillation
Rochester, MN
The purpose of this study is to determine and compare the safety and efficacy of transcutaneous afferent patterned stimulation (TAPS) and respiratory-gated auricular vagal afferent nerve stimulation (RAVANS) therapies for the reduction of paroxysmal atrial fibrillation (AF) burden.
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A Study to Evaluate Feasibility of Microburst Vagus Nerve Stimulator (VNS) Therapy
Jacksonville, FL
The purpose of this study is to evaluate the initial safety and effectiveness of Microburst VNS stimulation in subjects with refractory epilepsy.