SUMMARY
The clinical and research interests of Bradley F. Boeve, M.D., include normal aging, neurodegenerative disorders that cause cognitive impairment or dementia, neurogenetics, prion disorders, and neurological sleep disorders.
Specific disorders of interest include: mild cognitive impairment, Alzheimer's disease, Pick's disease, frontotemporal dementia, primary progressive aphasia, Lewy body dementia (dementia with Lewy bodies), corticobasal degeneration, progressive supranuclear palsy, posterior cortical atrophy, Creutzfeldt-Jakob disease, REM sleep behavior disorder, narcolepsy, and restless legs syndrome and periodic limb movement disorder.
Focus areas
- Frontotemporal lobar degeneration (FTLD). FTLD is the umbrella term encompassing frontotemporal dementia, primary progressive aphasia, corticobasal degeneration, progressive supranuclear palsy and related conditions. Dr. Boeve studies the clinical, neuropsychological, genetic, biofluid, neuroimaging and neuropathologic characteristics of FTLD.
- Lewy body disease. Dr. Boeve studies the clinical, neuropsychological, genetic, biofluid, neuroimaging and neuropathologic characteristics of Lewy body disease, which can be present clinically as mild cognitive impairment, Lewy body dementia (dementia with Lewy bodies) and related conditions.
- REM sleep behavior disorder (RBD). Dr. Boeve studies the clinical, neuropsychological, genetic, biofluid, neuroimaging, polysomnographic and neuropathologic characteristics of RBD.
- Alzheimer's disease. Dr. Boeve studies the clinical, neuropsychological, genetic, biofluid, neuroimaging and neuropathologic characteristics of typical and atypical Alzheimer's disease.
Significance to patient care
Dr. Boeve's hope is that through his research, better tools will be developed to predict those individuals who will develop a neurodegenerative disease, diagnose individuals as early as possible, and more optimally treat symptoms. He is particularly interested in how treatments can be used to slow down the rate of progression, delay the onset, or prevent the development of dementia and parkinsonism.
Professional highlights
- Co-principal investigator, North American Prodromal Synucleinopathy Consortium, 2018-present
- Professor of Lewy body dementia, The Little Family Foundation, 2018-present
- Chair, Coordinating Center, Research Centers of Excellence Program, Lewy Body Dementia Association, 2017-present
- Recipient, Sleep Science Award, American Academy of Neurology, 2018
- Co-principal investigator, Longitudinal Evaluation of Familial Frontotemporal Dementia, 2014-present