Chieh-Ju Chao, M.D.

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SUMMARY

Summary

Mayo Clinic researcher Chieh-Ju Chao, M.D., studies the development, optimization and evaluation of artificial intelligence (AI) systems within the field of cardiovascular medicine. With a background in cardiovascular imaging and computational methods, Dr. Chao is particularly focused on echocardiography-based AI applications. He aims to use advanced AI techniques to improve diagnostic accuracy and efficiency to enhance patient care.

Focus areas

• Echocardiography-based AI applications. Dr. Chao develops deep learning models to enhance diagnostic accuracy and functional assessment in cardiology. These models predict specific diagnoses and measurements, offering cost-effective solutions for patient identification and necessary workups.
• Unsupervised AI phenotyping of cardiac conditions. Dr. Chao creates AI pipelines for unsupervised clustering and phenotyping of cardiovascular diseases. These pipelines provide new data-driven insights for better classification systems and guidance for research directions.
• Multimodal and agentic AI approaches. Dr. Chao also explores vision and language foundation models and agentic frameworks for echocardiography reporting with human-AI interaction. These tools aim to enhance the current clinical workflow with an AI co-pilot.

Significance to patient care

Dr. Chao advances patient care by creating AI tools that make heart disease diagnosis more accurate and efficient. These tools can find patients who might have heart conditions, guide their care and improve their treatment. By using AI in medicine, Dr. Chao wants to make patient care better, reduce mistakes in diagnosis and support personalized treatments.

Professional highlights

• Inaugural AI-focused Mayo Clinic Scholar in collaboration with the Stanford University Institute for Human-Centered Artificial Intelligence, Stanford University, 2023-present.
• American College of Cardiology:
  • Fellow, 2025.
  • Honorable mention, Young Investigator Award competition, 2022.
• Artificial Intelligence-Machine Learning Enablement Award, Mayo Clinic Center for Digital Health and Mayo Clinic Office of Equity, Inclusion and Diversity with support from Dalio Philanthropies, 2025.
• Early-Career Development Grant for Echo Scientists (EDGES), American Society of Echocardiography, 2023.