SUMMARY
Yael N. Kusne, M.D., Ph.D., is a practicing hematologist who specializes in treating premyeloid and myeloid disorders, such as clonal hematopoiesis, clonal cytopenias, myelodysplastic syndromes, myeloproliferative neoplasms, chronic myeloid leukemia and bone marrow failure. Dr. Kusne conducts research on clonal hematopoiesis and germline mutations in these hematologic malignancies.
Focus areas
- Clonal hematopoiesis. Dr. Kusne studies how clonal hematopoiesis evolves over time and evaluates its role in clonal cytopenias and progression to malignancy. She is particularly interested in how cancer therapies influence these processes.
- Germline predisposition disorders. Dr. Kusne investigates the impact of germline mutations on the development and progression of premyeloid and myeloid malignancies. Her work seeks to clarify how these inherited factors contribute to cancer risk and disease trajectory.
Significance to patient care
Dr. Kusne studies how certain blood cells can change and grow, sometimes causing low blood counts or blood cancers. She also looks at how family history might increase the risk of these conditions.
By focusing on how treatments affect these changes, Dr. Kusne aims to find better ways to catch problems early and stop serious disease from starting. This knowledge leads to new tests, targeted treatments and personalized care plans. Through her work, people can get the right care at the right time, helping them live longer and healthier lives.