Location

Rochester, Minnesota

Contact

Maleszewski.Joseph@mayo.edu Clinical Profile

SUMMARY

Joseph J. Maleszewski, M.D., studies acquired and congenital forms of heart disease. His primary research focuses include neoplastic heart disease as well as the genetics and proteomics of both cardiomyopathies and aortic disease.

Focus areas

  • Molecular mechanisms involved in the formation of heart tumors, including cardiac myxoma, cardiac sarcomas and others
  • Proteomics and histopathologic risk stratification in cardiac amyloidosis
  • Genetic, proteomic and phenotypic features of cardiomyopathies, including dilated cardiomyopathy, hypertrophic cardiomyopathy and arrhythmogenic cardiomyopathy
  • Pathobiology of spontaneous coronary artery disease (SCAD)
  • Genotype-phenotype correlation of inherited forms of aortic diseases such as Marfan syndrome, Loeys-Dietz syndrome and congenitally bicuspid aortic valve
  • Molecular markers and histopathologic patterns of pulmonary vascular disease
  • Classification and nomenclature of congenital heart disease

Significance to patient care

Dr. Maleszewski's research aims to improve the diagnostic and prognostic approaches to cardiovascular and pulmonary disease.

PROFESSIONAL DETAILS

Primary Appointment

  1. Consultant, Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology

Joint Appointment

  1. Consultant, Division of Clinical Biochemistry & Immunology, Department of Laboratory Medicine and Pathology
  2. Consultant, Department of Medical Genetics
  3. Consultant, Department of Cardiovascular Medicine

Academic Rank

  1. Professor of Medicine
  2. Professor of Laboratory Medicine and Pathology

EDUCATION

  1. Fellow - Molecular Genetic Pathology Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  2. Fellow Molecular Genetic Pathology, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  3. Fellow - Cardiovascular Pathology Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  4. Resident - Anatomic & Clinical Pathology The Johns Hopkins University School of Medicine
  5. MD College of Human Medicine, Michigan State University
  6. BS - Physiology with a Specialization in Health and Humanities Lyman Briggs School, Michigan State University

Clinical Studies

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Publications

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BIO-20095734

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