Location

Rochester, Minnesota

Contact

riederer@mayo.edu Clinical Profile

SUMMARY

The research interests of Stephen J. Riederer, Ph.D., are in the technical development of magnetic resonance imaging (MRI). This includes use of the underlying MRI physics, development of new imaging techniques, and implementation of MRI that addresses clinically important problems.

Previous projects have been in the development of fast-scanning methods such as the fundamental method of view sharing, multishot echo-planar imaging, fast spin-echo fluid-attenuated inversion recovery (FLAIR) imaging of the brain and rapid gradient-echo imaging with nonstandard (centric) phase-encoding orders. Recent projects include adapting these methods to contrast-enhanced magnetic resonance angiography (CE-MRA) and dynamic contrast-enhanced (DCE) perfusion imaging.

Another central aspect of Dr. Riederer's research has been real-time signal processing. Developments have included magnetic resonance fluoroscopy, real-time line scanning, and operator-interactive triggering for CE-MRA and fetal imaging.

Current studies include the development of high-resolution imaging for DCE-MRI, diffusion-weighted imaging and T2-weighted spin-echo (T2SE) imaging, particularly as applied to imaging prostate cancer. A specific project is focused on developing methods for very high (1 mm or less) resolution in the slice direction of 2D multislice T2SE. This is expected to be useful not only for prostate MRI but also for MRI of many other anatomic regions.

Dr. Riederer has long been active in the training of graduate students. He teaches didactic courses at Mayo Clinic Graduate School of Biomedical Sciences in MRI physics, and he has mentored more than two dozen students to doctoral degrees, many of whom are now active in research careers of their own.

Focus areas

  • High-quality prostate MRI
  • High (super)-resolution T2SE imaging
  • Contrast-enhanced magnetic resonance angiography
  • Parallel acquisition techniques and receiver coil arrays
  • Dynamic contrast-enhanced MRI

Significance to patient care

Dr. Riederer's research team interacts routinely with radiologists and other clinicians for in vivo evaluation of new techniques. Many of the methods developed in Dr. Riederer's laboratory have been implemented commercially and are used daily in MRI systems worldwide.

Professional highlights

  • George M. Eisenberg Professor I, Mayo Clinic, 2024.
  • Distinguished Investigator Award, Academy of Radiology Research, 2012.
  • Distinguished Investigator Award, Mayo Clinic, 2010.
  • President, Society of Magnetic Resonance Angiography, 2008.
  • Gold Medal, International Society for Magnetic Resonance in Medicine, 2002.

PROFESSIONAL DETAILS

Primary Appointment

  1. Consultant, Department of Radiology

Joint Appointment

  1. Consultant, Department of Physiology & Biomedical Engineering

Academic Rank

  1. Professor of Radiology

EDUCATION

  1. Research Associate - Participated in the design of a rectilinear scanner for performing dual-photon bone mineral densitometry, subsequently converted into a product by the company Lunar Radiation. Department of Radiology, University of Wisconsin, Madison
  2. PhD - Medical Physics University of Wisconsin, Madison
  3. Research Assistant - Worked as a graduate student of Dr. Charles Mistretta. Contributed to the original physics and engineering development of realtime digital subtraction angiography (DSA). The technique as developed in this laboratory has become commonly used, clinically accepted, marketed commercially, and is a multimillion dollar industry. Worked in x-ray energy subtraction methods for doctoral dissertation and developed techniques for real time high order combination of images for three-beam iodine K-edge imaging. Department of Radiology, University of Wisconsin, Madison
  4. Fellow - WARF Fellow University of Wisconsin, Madison
  5. Research Assistant - Worked with Drs. David Chesler and Gordon Brownell in developing techniques for the suppression of Gibbs' ringing in tomographic reconstruction and in studying x-ray statistical requirements and the noise power spectrum of computed tomography and applications to design requirements of CT scanners. Physics Research Lab, Massachusetts General Hospital
  6. SM - Nuclear Engineering Massachusetts Institute of Technology
  7. Fellow - Applied Mathematics Massachusetts Institute of Technology
  8. Research Fellowship - Worked under the direction of senior laboratory staff (Drs. Donald Janney, James Breedlove) in simulating the transient behavior of shock waves in x-ray images. Los Alamos Scientific Laboratory
  9. BA - Mathematics University of Wisconsin, Madison
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BIO-00026656

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