Publications

1. Roddy GW, Kohli D, Niknam P, Omer ME, Chowdhury UR, Anderson KJ, Pacheco Marrero JM, Rinkoski TA, Fautsch MP. Subconjunctival Administration of an Adeno-Associated Virus Expressing Stanniocalcin-1 Provides Sustained Intraocular Pressure Reduction in Mice. Ophthalmol Sci. 2025 Jan-Feb; 5 (1):100590 Epub 2024 July 31
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2. Roy Chowdhury U, Fautsch MP. Human Anterior Segment Perfusion Organ Culture. Methods Mol Biol. 2025; 2858:87-100
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3. Saha S, Skeie JM, Schmidt GA, Eggleston T, Shevalye H, Sales CS, Phruttiwanichakun P, Dusane A, Field MG, Rinkoski TA, Fautsch MP, Baratz KH, Roy M, Jun AS, Pendleton C, Salem AK, Greiner MA. TCF4 trinucleotide repeat expansions and UV irradiation increase susceptibility to ferroptosis in Fuchs endothelial corneal dystrophy. Redox Biol. 2024 Nov; 77:103348 Epub 2024 Sept 10
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4. Tailor PD, Aul BJ, Sit AJ, Fautsch MP, Chen JJ. Determination of the Trans-Lamina Cribrosa Pressure Difference in a Community-Based Population and its Association with Open-Angle Glaucoma. Ophthalmol Glaucoma. 2024 Mar-Apr; 7 (2):168-176 Epub 2023 Oct 01
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5. Miley DR, Andrews-Pfannkoch CM, Pulido JS, Erickson SA, Vile RG, Fautsch MP, Marmorstein AD, Dalvin LA. Direct early growth response-1 knockdown decreases melanoma viability independent of mitogen-activated extracellular signal-related kinase inhibition. Melanoma Res. 2023 Dec 1; 33 (6):482-491 Epub 2023 Aug 25
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6. Roy Chowdhury U, Pervan-Steel CL, Sheeler R, Sookdeo HK, Rogers B, Casale R, Dosa PI, Htoo T, Wirostko BM, Fautsch MP. Preclinical Pharmacokinetic Profile of Topical Ophthalmic and Intravenous Delivery of QLS-101, a Novel ATP-Sensitive Potassium Channel Opening Ocular Hypotensive Agent. J Ocul Pharmacol Ther. 2023 Jun; 39 (5):332-346 Epub 2023 May 17
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7. Xu TT, Baratz KH, Fautsch MP, Hodge DO, Mahr MA. Cancer Risk in Patients With Fuchs Endothelial Corneal Dystrophy. Cornea. 2022 Sep 1; 41 (9):1088-1093 Epub 2021 Sept 27
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8. Hann CR, Bentley MD, Vercnocke A, Roy Chowdhury U, Fautsch MP. Evaluation of neural innervation in the human conventional outflow pathway distal to Schlemm's canal. Exp Eye Res. 2022 Aug; 221:109132 Epub 2022 May 27
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9. Roy Chowdhury U, Fautsch MP. Isolation and Culture of Vascular Distal Outflow Pathway (VDOP) Cells From Human Donor Eyes. Curr Protoc. 2022 Aug; 2 (8):e528
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10. Pervan-Steel CL, Roy Chowdhury U, Sookdeo HK, Casale RA, Dosa PI, Htoo TM, Fautsch MP, Wirostko BM. Ocular Hypotensive Properties and Biochemical Profile of QLS-101, a Novel ATP-Sensitive Potassium (KATP) Channel Opening Prodrug. Invest Ophthalmol Vis Sci. 2022 Apr 1; 63 (4):26
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11. Roy Chowdhury U, Millar JC, Holman BH, Anderson KJ, Dosa PI, Roddy GW, Fautsch MP. Effect of ATP-sensitive Potassium Channel Openers on Intraocular Pressure in Ocular Hypertensive Animal Models. Invest Ophthalmol Vis Sci. 2022 Feb 1; 63 (2):15
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12. McDowell CM, Kizhatil K, Elliott MH, Overby DR, van Batenburg-Sherwood J, Millar JC, Kuehn MH, Zode G, Acott TS, Anderson MG, Bhattacharya SK, Bertrand JA, Borras T, Bovenkamp DE, Cheng L, Danias J, De Ieso ML, Du Y, Faralli JA, Fuchshofer R, Ganapathy PS, Gong H, Herberg S, Hernandez H, Humphries P, John SWM, Kaufman PL, Keller KE, Kelley MJ, Kelly RA, Krizaj D, Kumar A, Leonard BC, Lieberman RL, Liton P, Liu Y, Liu KC, Lopez NN, Mao W, Mavlyutov T, McDonnell F, McLellan GJ, Mzyk P, Nartey A, Pasquale LR, Patel GC, Pattabiraman PP, Peters DM, Raghunathan V, Rao PV, Rayana N, Raychaudhuri U, Reina-Torres E, Ren R, Rhee D, Chowdhury UR, Samples JR, Samples EG, Sharif N, Schuman JS, Sheffield VC, Stevenson CH, Soundararajan A, Subramanian P, Sugali CK, Sun Y, Toris CB, Torrejon KY, Vahabikashi A, Vranka JA, Wang T, Willoughby CE, Xin C, Yun H, Zhang HF, Fautsch MP, Tamm ER, Clark AF, Ethier CR, Stamer WD. Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms. Invest Ophthalmol Vis Sci. 2022 Feb 1; 63 (2):12
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13. Roddy GW, Roy Chowdhury U, Anderson KJ, Rinkoski TA, Hann CR, Chiodo VA, Smith WC, Fautsch MP. Transgene expression of Stanniocalcin-1 provides sustained intraocular pressure reduction by increasing outflow facility. PLoS One. 2022; 17 (5):e0269261 Epub 2022 May 31
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14. Kinariwala BB, Xu TT, Baratz KH, Aleff RA, Patel SV, Maguire LJ, Fautsch MP, Wieben ED, Millen AE, Patel SP. Relationship of Body Mass Index With Fuchs Endothelial Corneal Dystrophy Severity and TCF4 CTG18.1 Trinucleotide Repeat Expansion. Cornea. 2021 Dec 1; 40 (12):1567-1570
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15. Roddy GW, Chowdhury UR, Monson KJ, Fautsch MP. Stanniocalcin-1 Reduced Intraocular Pressure in Two Models of Ocular Hypertension. Curr Eye Res. 2021 Oct; 46 (10):1525-1530 Epub 2021 Mar 24
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16. Roy Chowdhury U, Kudgus RA, Holman BH, Rinkoski TA, Hann CR, Bahler CK, McCloud E, Appt SE, Reid JM, Dosa PI, Fautsch MP. Pharmacological Profile and Ocular Hypotensive Effects of Cromakalim Prodrug 1, a Novel ATP-Sensitive Potassium Channel Opener, in Normotensive Dogs and Nonhuman Primates. J Ocul Pharmacol Ther. 2021 Jun; 37 (5):251-260 Epub 2021 Mar 30
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17. Fautsch MP, Wieben ED, Baratz KH, Bhattacharyya N, Sadan AN, Hafford-Tear NJ, Tuft SJ, Davidson AE. TCF4-mediated Fuchs endothelial corneal dystrophy: Insights into a common trinucleotide repeat-associated disease. Prog Retin Eye Res. 2021 Mar; 81:100883 Epub 2020 July 28
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18. Roy Chowdhury U, Bahler CK, Hann CR, Holman BH, Fautsch MP. Isolation and characterization of novel primary cells from the human distal outflow pathway. Sci Rep. 2021 Feb 17; 11 (1):4034
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19. Xu TT, Li YJ, Afshari NA, Aleff RA, Rinkoski TA, Patel SV, Maguire LJ, Edwards AO, Brown WL, Fautsch MP, Wieben ED, Baratz KH. Disease Expression and Familial Transmission of Fuchs Endothelial Corneal Dystrophy With and Without CTG18.1 Expansion. Invest Ophthalmol Vis Sci. 2021 Jan 4; 62 (1):17
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20. Wieben ED, Aleff RA, Rinkoski TA, Baratz KH, Basu S, Patel SV, Maguire LJ, Fautsch MP. Comparison of TCF4 repeat expansion length in corneal endothelium and leukocytes of patients with Fuchs endothelial corneal dystrophy. PLoS One. 2021; 16 (12):e0260837 Epub 2021 Dec 02
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21. Sagaser S, Butterfield R, Kosiorek H, Kusne Y, Maldonado J, Fautsch MP, Patel D, Shen JF. Effects of Intense Pulsed Light on Tear Film TGF-beta and Microbiome in Ocular Rosacea with Dry Eye. Clin Ophthalmol. 2021; 15:323-330 Epub 2021 Jan 27
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22. Rinkoski TA, Bahler CK, Pacheco JM, Khanna ML, Holmes DM, Roy Chowdhury U, Baratz KH, Patel SV, Maguire LJ, Wieben ED, Fautsch MP. Characterization of a dual media system for culturing primary normal and Fuchs endothelial corneal dystrophy (FECD) endothelial cells. PLoS One. 2021; 16 (9):e0258006 Epub 2021 Sept 29
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23. Roddy GW, Rosa RH, Viker KB, Holman BH, Hann CR, Krishnan A, Gores GJ, Bakri SJ, Fautsch MP. Diet Mimicking "Fast Food" Causes Structural Changes to the Retina Relevant to Age-Related Macular Degeneration. Curr Eye Res. 2020 Jun; 45 (6):726-732 Epub 2019 Dec 02
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24. Ferguson TJ, Knier CG, Chowdhury UR, Monson KJ, Greenwood M, Swan RJ, Gorham R, Berdahl JP, Fautsch MP. Intraocular Pressure Measurement with Pneumatonometry and a Tonometer Tip Cover. Ophthalmol Ther. 2020 Mar; 9 (1):127-137 Epub 2020 Feb 20
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25. Roddy GW, Rinkoski TA, Monson KJ, Chowdhury UR, Fautsch MP. Stanniocalcin-1 (STC-1), a downstream effector molecule in latanoprost signaling, acts independent of the FP receptor for intraocular pressure reduction. PLoS One. 2020; 15 (5):e0232591 Epub 2020 May 04
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26. Roy Chowdhury U, Kudgus RA, Rinkoski TA, Holman BH, Bahler CK, Hann CR, Reid JM, Dosa PI, Fautsch MP. Pharmacological and pharmacokinetic profile of the novel ocular hypotensive prodrug CKLP1 in Dutch-belted pigmented rabbits. PLoS One. 2020; 15 (4):e0231841 Epub 2020 Apr 16
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27. Gandhi JK, Mano F, Iezzi R Jr, LoBue SA, Holman BH, Fautsch MP, Olsen TW, Pulido JS, Marmorstein AD. Fibrin hydrogels are safe, degradable scaffolds for sub-retinal implantation. PLoS One. 2020; 15 (1):e0227641 Epub 2020 Jan 13
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28. Knier CG, Fleischman D, Hodge DO, Berdahl JP, Fautsch MP. Three-Decade Evaluation of Cerebrospinal Fluid Pressure in Open-Angle Glaucoma at a Tertiary Care Center. J Ophthalmol. 2020; 2020:7487329 Epub 2020 Nov 11
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29. Dalvin LA, Hartnett ME, Bretz CA, Hann CR, Cui RZ, Marmorstein AD, Sheikh-Hamad D, Fautsch MP, Roddy GW. Stanniocalcin-1 is a Modifier of Oxygen-Induced Retinopathy Severity. Curr Eye Res. 2020 Jan; 45 (1):46-51 Epub 2019 Aug 28
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30. Wieben ED, Baratz KH, Aleff RA, Kalari KR, Tang X, Maguire LJ, Patel SV, Fautsch MP. Gene Expression and Missplicing in the Corneal Endothelium of Patients With a TCF4 Trinucleotide Repeat Expansion Without Fuchs' Endothelial Corneal Dystrophy. Invest Ophthalmol Vis Sci. 2019 Aug 1; 60 (10):3636-3643
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31. Okumura N, Hayashi R, Nakano M, Tashiro K, Yoshii K, Aleff R, Butz M, Highsmith EW, Wieben ED, Fautsch MP, Baratz KH, Komori Y, Ueda E, Nakahara M, Weller J, Tourtas T, Schlotzer-Schrehardt U, Kruse F, Koizumi N. Association of rs613872 and Trinucleotide Repeat Expansion in the TCF4 Gene of German Patients With Fuchs Endothelial Corneal Dystrophy. Cornea. 2019 Jul; 38 (7):799-805
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32. Okumura N, Hayashi R, Nakano M, Yoshii K, Tashiro K, Sato T, Blake DJ, Aleff R, Butz M, Highsmith EW, Wieben ED, Fautsch MP, Baratz KH, Komori Y, Nakahara M, Tourtas T, Schlotzer-Schrehardt U, Kruse F, Koizumi N. Effect of Trinucleotide Repeat Expansion on the Expression of TCF4 mRNA in Fuchs' Endothelial Corneal Dystrophy. Invest Ophthalmol Vis Sci. 2019 Feb 1; 60 (2):779-786
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33. Roy Chowdhury U, Dosa PI, Fautsch MP. ATP sensitive potassium channel openers: A new class of ocular hypotensive agents. Exp Eye Res 2019 Jan; 178:225 Epub 2016 June 25
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34. Tribble JR, Vasalauskaite A, Redmond T, Young RD, Hassan S, Fautsch MP, Sengpiel F, Williams PA, Morgan JE. Midget retinal ganglion cell dendritic and mitochondrial degeneration is an early feature of human glaucoma. Brain Commun. 2019; 1 (1):fcz035 Epub 2019 Nov 28
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35. Wieben ED, Aleff RA, Basu S, Sarangi V, Bowman B, McLaughlin IJ, Mills JR, Butz ML, Highsmith EW, Ida CM, Ekholm JM, Baratz KH, Fautsch MP. Amplification-free long-read sequencing of TCF4 expanded trinucleotide repeats in Fuchs Endothelial Corneal Dystrophy. PLoS One. 2019; 14 (7):e0219446 Epub 2019 July 05
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36. Patterson-Orazem AC, Hill SE, Fautsch MP, Lieberman RL. Epitope mapping of commercial antibodies that detect myocilin. Exp Eye Res. 2018 Aug; 173:109-112 Epub 2018 May 09
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37. Winkler NS, Milone M, Martinez-Thompson JM, Raja H, Aleff RA, Patel SV, Fautsch MP, Wieben ED, Baratz KH. Fuchs' Endothelial Corneal Dystrophy in Patients With Myotonic Dystrophy, Type 1. Invest Ophthalmol Vis Sci. 2018 Jun 1; 59 (7):3053-3057
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38. Keller KE, Bhattacharya SK, Borras T, Brunner TM, Chansangpetch S, Clark AF, Dismuke WM, Du Y, Elliott MH, Ethier CR, Faralli JA, Freddo TF, Fuchshofer R, Giovingo M, Gong H, Gonzalez P, Huang A, Johnstone MA, Kaufman PL, Kelley MJ, Knepper PA, Kopczynski CC, Kuchtey JG, Kuchtey RW, Kuehn MH, Lieberman RL, Lin SC, Liton P, Liu Y, Lutjen-Drecoll E, Mao W, Masis-Solano M, McDonnell F, McDowell CM, Overby DR, Pattabiraman PP, Raghunathan VK, Rao PV, Rhee DJ, Chowdhury UR, Russell P, Samples JR, Schwartz D, Stubbs EB, Tamm ER, Tan JC, Toris CB, Torrejon KY, Vranka JA, Wirtz MK, Yorio T, Zhang J, Zode GS, Fautsch MP, Peters DM, Acott TS, Stamer WD. Consensus recommendations for trabecular meshwork cell isolation, characterization and culture. Exp Eye Res. 2018 Jun; 171:164-173 Epub 2018 Mar 09
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39. Wacker K, Baratz KH, Fautsch MP, Patel SV. Medical and Semi-surgical Treatments for Fuchs Endothelial Corneal Dystrophy. Klin Monbl Augenheilkd. 2018 Jun; 235 (6):709-713 Epub 2018 May 03
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40. Soragni E, Petrosyan L, Rinkoski TA, Wieben ED, Baratz KH, Fautsch MP, Gottesfeld JM. Repeat-Associated Non-ATG (RAN) Translation in Fuchs' Endothelial Corneal Dystrophy. Invest Ophthalmol Vis Sci. 2018 Apr 1; 59 (5):1888-1896
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41. Wieben ED, Aleff RA, Tang X, Kalari KR, Maguire LJ, Patel SV, Baratz KH, Fautsch MP. Gene expression in the corneal endothelium of Fuchs endothelial corneal dystrophy patients with and without expansion of a trinucleotide repeat in TCF4. PLoS One. 2018; 13 (7):e0200005 Epub 2018 July 02
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42. Roddy GW, Yasumura D, Matthes MT, Alavi MV, Boye SL, Rosa RH Jr, Fautsch MP, Hauswirth WW, LaVail MM. Long-term photoreceptor rescue in two rodent models of retinitis pigmentosa by adeno-associated virus delivery of Stanniocalcin-1. Exp Eye Res. 2017 Dec; 165:175-181 Epub 2017 Sept 30
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43. Roy Chowdhury U, Rinkoski TA, Bahler CK, Millar JC, Bertrand JA, Holman BH, Sherwood JM, Overby DR, Stoltz KL, Dosa PI, Fautsch MP. Effect of Cromakalim Prodrug 1 (CKLP1) on Aqueous Humor Dynamics and Feasibility of Combination Therapy With Existing Ocular Hypotensive Agents. Invest Ophthalmol Vis Sci. 2017 Nov 1; 58 (13):5731-5742
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44. Gandhi JK, Roy Chowdhury U, Manzar Z, Buck J, Levin LR, Fautsch MP, Marmorstein AD. Differential Intraocular Pressure Measurements by Tonometry and Direct Cannulation After Treatment with Soluble Adenylyl Cyclase Inhibitors. J Ocul Pharmacol Ther. 2017 Oct; 33 (8):574-581 Epub 2017 July 07
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45. Roy Chowdhury U, Dosa PI, Fautsch MP. ATP sensitive potassium channel openers: A new class of ocular hypotensive agents. Exp Eye Res. 2017 May; 158:85-93 Epub 2016 Apr 26
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46. Roddy GW, Viker KB, Winkler NS, Bahler CK, Holman BH, Sheikh-Hamad D, Roy Chowdhury U, Stamer WD, Fautsch MP. Stanniocalcin-1 Is an Ocular Hypotensive Agent and a Downstream Effector Molecule That Is Necessary for the Intraocular Pressure-Lowering Effects of Latanoprost. Invest Ophthalmol Vis Sci. 2017 May 1; 58 (5):2715-2724
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47. Roy Chowdhury U, Bahler CK, Holman BH, Fautsch MP. ATP-sensitive potassium (KATP) channel openers diazoxide and nicorandil lower intraocular pressure by activating the Erk1/2 signaling pathway. PLoS One. 2017; 12 (6):e0179345 Epub 2017 June 08
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48. Wieben ED, Aleff RA, Tang X, Butz ML, Kalari KR, Highsmith EW, Jen J, Vasmatzis G, Patel SV, Maguire LJ, Baratz KH, Fautsch MP. Trinucleotide Repeat Expansion in the Transcription Factor 4 (TCF4) Gene Leads to Widespread mRNA Splicing Changes in Fuchs' Endothelial Corneal Dystrophy. Invest Ophthalmol Vis Sci. 2017 Jan 1; 58 (1):343-352
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49. Fleischman D, Bicket AK, Stinnett SS, Berdahl JP, Jonas JB, Wang NL, Fautsch MP, Allingham RR. Analysis of Cerebrospinal Fluid Pressure Estimation Using Formulae Derived From Clinical Data. Invest Ophthalmol Vis Sci. 2016 Oct 1; 57 (13):5625-5630
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50. Roy Chowdhury U, Viker KB, Stoltz KL, Holman BH, Fautsch MP, Dosa PI. Analogs of the ATP-Sensitive Potassium (KATP) Channel Opener Cromakalim with in Vivo Ocular Hypotensive Activity. J Med Chem. 2016 Jul 14; 59 (13):6221-31 Epub 2016 July 01
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51. Loewen RT, Roy P, Park DB, Jensen A, Scott G, Cohen-Karni D, Fautsch MP, Schuman JS, Loewen NA. A Porcine Anterior Segment Perfusion and Transduction Model With Direct Visualization of the Trabecular Meshwork. Invest Ophthalmol Vis Sci. 2016 Mar; 57 (3):1338-44
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52. Bentley MD, Hann CR, Fautsch MP. Anatomical Variation of Human Collector Channel Orifices. Invest Ophthalmol Vis Sci. 2016 Mar; 57 (3):1153-9
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53. Roy Chowdhury U, Fautsch MP. Intracranial Pressure and Its Relationship to Glaucoma: Current Understanding and Future Directions. Med Hypothesis Discov Innov Ophthalmol. 2015 Fall; 4 (3):71-80
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54. Parthasarathy R, Chow KM, Derafshi Z, Fautsch MP, Hetling JR, Rodgers DW, Hersh LB, Pepperberg DR. Reduction of amyloid-beta levels in mouse eye tissues by intra-vitreally delivered neprilysin. Exp Eye Res. 2015 Sep; 138:134-44 Epub 2015 July 02
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55. Hann CR, Fautsch MP. Recent Developments in Understanding the Role of Aqueous Humor Outflow in Normal and Primary Open Angle Glaucoma. Curr Ophthalmol Rep. 2015 Jun 1; 3 (2):67-73
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56. Jones HJ, Girard MJ, White N, Fautsch MP, Morgan JE, Ethier CR, Albon J. Quantitative analysis of three-dimensional fibrillar collagen microstructure within the normal, aged and glaucomatous human optic nerve head. J R Soc Interface. 2015 May 6; 12 (106)
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57. Roy Chowdhury U, Hann CR, Stamer WD, Fautsch MP. Aqueous humor outflow: dynamics and disease. Invest Ophthalmol Vis Sci. 2015 May; 56 (5):2993-3003
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58. Dalvin LA, Fautsch MP. Analysis of Circadian Rhythm Gene Expression With Reference to Diurnal Pattern of Intraocular Pressure in Mice. Invest Ophthalmol Vis Sci. 2015 Apr 1; 56(4):2657-63.
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59. Roy Chowdhury U, Bahler CK, Holman BH, Dosa PI, Fautsch MP. Ocular Hypotensive Effects of the ATP-Sensitive Potassium Channel Opener Cromakalim in Human and Murine Experimental Model Systems. PLoS One. 2015; 10 (11):e0141783 Epub 2015 Nov 04
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60. Roy Chowdhury U, Fautsch MP. Intracranial pressure and its relationship with glaucoma: Current understanding and future directions. Med Hypothesis Discov Innov Ophthlamol In Press. In press, 2015.
    
61. Hann CR, Vercnocke AJ, Bentley MD, Jorgensen SM, Fautsch MP. Anatomic changes in Schlemm's canal and collector channels in normal and primary open-angle glaucoma eyes using low and high perfusion pressures. Invest Ophthalmol Vis Sci. 2014 Aug 19; 55 (9):5834-41
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62. Winkler NS, Fautsch MP. Effects of prostaglandin analogues on aqueous humor outflow pathways. J Ocul Pharmacol Ther. 2014 Mar-Apr; 30 (2-3):102-9 Epub 2013 Dec 20
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63. Chowdhury UR, Holman BH, Fautsch MP. ATP-sensitive potassium (K(ATP)) channel openers diazoxide and nicorandil lower intraocular pressure in vivo. Invest Ophthalmol Vis Sci. 2013 Jul 22; 54 (7):4892-9 Epub 2013 July 22
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64. Kuchtey J, Chowdhury UR, Uptegraft CC, Fautsch MP, Kuchtey RW. A de novo MYOC mutation detected in juvenile open angle glaucoma associated with reduced myocilin protein in aqueous humor. Eur J Med Genet. 2013 Jun; 56(6):292-6. Epub 2013 Mar 19.
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65. Roy Chowdhury U, Holman BH, Fautsch MP. A novel rat model to study the role of intracranial pressure modulation on optic neuropathies. PLoS One. 2013; 8 (12):e82151 Epub 2013 Dec 18
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66. Bahler CK, Hann CR, Fjield T, Haffner D, Heitzmann H, Fautsch MP. Second-generation trabecular meshwork bypass stent (iStent inject) increases outflow facility in cultured human anterior segments. Am J Ophthalmol. 2012 Jun; 153 (6):1206-13 Epub 2012 Mar 30
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67. Berdahl JP, Fleischman D, Zaydlarova J, Stinnett S, Allingham RR, Fautsch MP. Body mass index has a linear relationship with cerebrospinal fluid pressure. Invest Ophthalmol Vis Sci. 2012 Mar; 53(3):1422-7. Epub 2012 Mar 15.
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68. Fleischman D, Berdahl JP, Zaydlarova J, Stinnett S, Fautsch MP, Allingham RR. Cerebrospinal fluid pressure decreases with older age. PLoS One. 2012; 7(12):e52664. Epub 2012 Dec 26.
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69. Chowdhury UR, Bahler CK, Hann CR, Chang M, Resch ZT, Romero MF, Fautsch MP. ATP-sensitive potassium (KATP) channel activation decreases intraocular pressure in the anterior chamber of the eye. Invest Ophthalmol Vis Sci. 2011 Aug 16; 52 (9):6435-42
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70. Chowdhury UR, Jea SY, Oh DJ, Rhee DJ, Fautsch MP. Expression profile of the matricellular protein osteopontin in primary open-angle glaucoma and the normal human eye. Invest Ophthalmol Vis Sci. 2011 Aug 16; 52 (9):6443-51
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71. Lei Y, Garrahan N, Hermann B, Fautsch MP, Johnson DH, Hernandez MR, Boulton M, Morgan JE. Transretinal degeneration in ageing human retina: a multiphoton microscopy analysis. Br J Ophthalmol. 2011 May; 95(5):727-30. Epub 2010 Dec 22.
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72. Last JA, Pan T, Ding Y, Reilly CM, Keller K, Acott TS, Fautsch MP, Murphy CJ, Russell P. Elastic modulus determination of normal and glaucomatous human trabecular meshwork. Invest Ophthalmol Vis Sci. 2011 Apr; 52(5):2147-52. Epub 2011 Apr 05.
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73. Hann CR, Bentley MD, Vercnocke A, Ritman EL, Fautsch MP. Imaging the aqueous humor outflow pathway in human eyes by three-dimensional micro-computed tomography (3D micro-CT). Exp Eye Res. 2011 Feb; 92 (2):104-11 Epub 2010 Dec 25
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74. Hann CR, Fautsch MP. The elastin fiber system between and adjacent to collector channels in the human juxtacanalicular tissue. Invest Ophthalmol Vis Sci. 2011 Jan; 52 (1):45-50 Epub 2011 Jan 05
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75. Howell KG, Vrabel AM, Chowdhury UR, Stamer WD, Fautsch MP. Myocilin levels in primary open-angle glaucoma and pseudoexfoliation glaucoma human aqueous humor. J Glaucoma. 2010 Dec; 19 (9):569-75
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76. Resch ZT, Hann CR, Cook KA, Fautsch MP. Aqueous humor rapidly stimulates myocilin secretion from human trabecular meshwork cells. Exp Eye Res. 2010 Dec; 91 (6):901-8 Epub 2010 Oct 07
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77. Chowdhury UR, Madden BJ, Charlesworth MC, Fautsch MP. Proteome analysis of human aqueous humor. Invest Ophthalmol Vis Sci. 2010 Oct; 51 (10):4921-31 Epub 2010 May 12
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78. Lei Y, Garrahan N, Hermann B, Fautsch MP, Johnson DH, Hernandez MR, Boulton M, Morgan JE. Topography of neuron loss in the retinal ganglion cell layer in human glaucoma. Br J Ophthalmol. 2009 Dec; 93(12):1676-9. Epub 2009 Aug 10.
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79. Patel SV, Bachman LA, Hann CR, Bahler CK, Fautsch MP. Human corneal endothelial cell transplantation in a human ex vivo model. Invest Ophthalmol Vis Sci. 2009 May; 50 (5):2123-31 Epub 2009 Jan 10
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80. Johnson M, Fautsch MP. Douglas H. Johnson: a tribute. Exp Eye Res. 2009 Apr; 88(4):620-30. Epub 2008 Nov 30.
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81. Hann CR, Fautsch MP. Preferential fluid flow in the human trabecular meshwork near collector channels. Invest Ophthalmol Vis Sci. 2009 Apr; 50 (4):1692-7 Epub 2008 Dec 05
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82. Resch ZT, Fautsch MP. Glaucoma-associated myocilin: a better understanding but much more to learn. Exp Eye Res. 2009 Apr; 88 (4):704-12 Epub 2008 Aug 29
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83. Berdahl JP, Fautsch MP, Stinnett SS, Allingham RR. Intracranial pressure in primary open angle glaucoma, normal tension glaucoma, and ocular hypertension: a case-control study. Invest Ophthalmol Vis Sci. 2008 Dec; 49(12):5412-8. Epub 2008 Aug 21.
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84. Ezzat MK, Howell KG, Bahler CK, Beito TG, Loewen N, Poeschla EM, Fautsch MP. Characterization of monoclonal antibodies against the glaucoma-associated protein myocilin. Exp Eye Res. 2008 Oct; 87 (4):376-84 Epub 2008 July 12
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85. Bahler CK, Howell KG, Hann CR, Fautsch MP, Johnson DH. Prostaglandins increase trabecular meshwork outflow facility in cultured human anterior segments. Am J Ophthalmol. 2008 Jan; 145 (1):114-9 Epub 2007 Nov 07
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86. Fautsch MP, Johnson DH. Aqueous humor outflow: what do we know? Where will it lead us? Invest Ophthalmol Vis Sci. 2006 Oct; 47 (10):4181-7
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87. Wren SM, Leske DA, Mutapcic L, Fautsch MP, Holmes JM. The effect of L-thyroxine supplementation in a neonatal rat model of ROP. Curr Eye Res. 2006 Jul-Aug; 31(7-8):669-74.
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88. Fautsch MP, Vrabel AM, Johnson DH. The identification of myocilin-associated proteins in the human trabecular meshwork. Exp Eye Res. 2006 Jun; 82(6):1046-52. Epub 2005 Nov 11.
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89. Fautsch MP, Vrabel AM, Johnson DH. Characterization of the Felix domesticus (cat) glaucoma-associated protein myocilin. Exp Eye Res. 2006 Jun; 82(6):1037-45. Epub 2005 Nov 10.
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90. Leske DA, Wu J, Mookadam M, Chen Y, Fautsch MP, Holmes JM, Lanier WL. The relationship of retinal VEGF and retinal IGF-1 mRNA with neovascularization in an acidosis-induced model of retinopathy of prematurity. Curr Eye Res. 2006 Feb; 31(2):163-9.
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91. Park BC, Shen X, Fautsch MP, Tibudan M, Johnson DH, Yue BY. Optimized bacterial expression of myocilin proteins and functional comparison of bacterial and eukaryotic myocilins. Mol Vis. 2006; 12:832-40. Epub 2006 Jul 31.
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92. Fautsch MP, Bahler CK, Vrabel AM, Howell KG, Loewen N, Teo WL, Poeschla EM, Johnson DH. Perfusion of his-tagged eukaryotic myocilin increases outflow resistance in human anterior segments in the presence of aqueous humor. Invest Ophthalmol Vis Sci. 2006 Jan; 47(1):213-21.
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93. Mutapcic L, Wren SM, Leske DA, Fautsch MP, Holmes JM. The effect of L-thyroxine supplementation on retinal vascular development in neonatal rats. Curr Eye Res. 2005 Dec; 30(12):1035-40.
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94. Fautsch MP, Howell KG, Vrabel AM, Charlesworth MC, Muddiman DC, Johnson DH. Primary trabecular meshwork cells incubated in human aqueous humor differ from cells incubated in serum supplements. Invest Ophthalmol Vis Sci. 2005 Aug; 46(8):2848-56.
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95. Berdahl JP, Leske DA, Fautsch MP, Lanier WL, Holmes JM. Effect of bicarbonate on retinal vasculature and acidosis-induced retinopathy in the neonatal rat. Graefes Arch Clin Exp Ophthalmol. 2005 Apr; 243 (4):367-73 Epub 2004 Nov 19
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96. Floyd BN, Leske DA, Wren SM, Mookadam M, Fautsch MP, Holmes JM. Differences between rat strains in models of retinopathy of prematurity. Mol Vis. 2005; 11:524-30. Epub 2005 Jul 19.
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97. Mookadam M, Leske DA, Fautsch MP, Lanier WL, Holmes JM. Anti-thyroid methimazole in an acidosis-induced retinopathy rat model of retinopathy of prematurity. Mol Vis. 2005; 11:909-15. Epub 2005 Nov 02.
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98. Mookadam M, Leske DA, Fautsch MP, Lanier WL, Holmes JM. The anti-thyroid drug methimazole induces neovascularization in the neonatal rat analogous to ROP. Invest Ophthalmol Vis Sci. 2004 Nov; 45(11):4145-50.
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99. Loewen N, Fautsch MP, Teo WL, Bahler CK, Johnson DH, Poeschla EM. Long-term, targeted genetic modification of the aqueous humor outflow tract coupled with noninvasive imaging of gene expression in vivo. Invest Ophthalmol Vis Sci. 2004 Sep; 45(9):3091-8.
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100. Bahler CK, Fautsch MP, Hann CR, Johnson DH. Factors influencing intraocular pressure in cultured human anterior segments. Invest Ophthalmol Vis Sci. 2004 Sep; 45(9):3137-43.
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101. Bahler CK, Hann CR, Fautsch MP, Johnson DH. Pharmacologic disruption of Schlemm's canal cells and outflow facility in anterior segments of human eyes. Invest Ophthalmol Vis Sci. 2004 Jul; 45 (7):2246-54
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102. Fautsch MP, Vrabel AM, Peterson SL, Johnson DH. In vitro and in vivo characterization of disulfide bond use in myocilin complex formation. Mol Vis. 2004 Jun 27; 10:417-25.
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103. Loewen N, Leske DA, Cameron JD, Chen Y, Whitwam T, Simari RD, Teo WL, Fautsch MP, Poeschla EM, Holmes JM. Long-term retinal transgene expression with FIV versus adenoviral vectors. Mol Vis. 2004 Apr 13; 10(35):272-80.
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104. Leske DA, Wu J, Fautsch MP, Karger RA, Berdahl JP, Lanier WL, Holmes JM. The role of VEGF and IGF-1 in a hypercarbic oxygen-induced retinopathy rat model of ROP. Mol Vis. 2004 Jan 21; 10:43-50.
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105. Fautsch MP, Silva AO, Johnson DH. Carbohydrate binding proteins galectin-1 and galectin-3 in human trabecular meshwork. Exp Eye Res. 2003 Jul; 77 (1):11-6
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106. Loewen N, Bahler C, Teo WL, Whitwam T, Peretz M, Xu R, Fautsch MP, Johnson DH, Poeschla EM. Preservation of aqueous outflow facility after second-generation FIV vector-mediated expression of marker genes in anterior segments of human eyes. Invest Ophthalmol Vis Sci. 2002 Dec; 43 (12):3686-90
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107. Loewen N, Fautsch MP, Peretz M, Bahler CK, Cameron JD, Johnson DH, Poeschla EM. Genetic modification of human trabecular meshwork with lentiviral vectors. Hum Gene Ther. 2001 Nov 20; 12(17):2109-19.
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108. Fautsch MP, Johnson DH. Characterization of myocilin-myocilin interactions. Invest Ophthalmol Vis Sci. 2001 Sep; 42(10):2324-31.
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109. Session DR, Fautsch MP, Avula R, Jones WR, Nehra A, Wieben ED. Cyclin-dependent kinase 5 is expressed in both Sertoli cells and metaphase spermatocytes. Fertil Steril. 2001 Apr; 75 (4):669-73
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110. Fautsch MP, Bahler CK, Jewison DJ, Johnson DH. Recombinant TIGR/MYOC increases outflow resistance in the human anterior segment. Invest Ophthalmol Vis Sci. 2000 Dec; 41 (13):4163-8
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111. Fautsch MP, Vrabel A, Rickard D, Subramaniam M, Spelsberg TC, Wieben ED. Characterization of the mouse TGFbeta-inducible early gene (TIEG): conservation of exon and transcriptional regulatory sequences with evidence of additional transcripts. Mamm Genome. 1998 Oct; 9 (10):838-42
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112. Fautsch MP, Vrabel A, Subramaniam M, Hefferen TE, Spelsberg TC, Wieben ED. TGFbeta-inducible early gene (TIEG) also codes for early growth response alpha (EGRalpha): evidence of multiple transcripts from alternate promoters. Genomics. 1998 Aug 1; 51(3):408-16.
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113. Fautsch MP, Perdok MM, Wieben ED. Production of SVP-1/-3/-4 in guinea pig testis. Characterization of novel transcripts containing long 5'-untranslated regions and multiple upstream AUG codons. J Biol Chem. 1997 Sep 26; 272 (39):24691-5
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114. Hagstrom JE, Fautsch MP, Perdok M, Vrabel A, Wieben ED. Exons lost and found. Unusual evolution of a seminal vesicle transglutaminase substrate. J Biol Chem. 1996 Aug 30; 271 (35):21114-9
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115. Specks U, Fass DN, Fautsch MP, Hummel AM, Viss MA. Recombinant human proteinase 3, the Wegener's autoantigen, expressed in HMC-1 cells is enzymatically active and recognized by c-ANCA. FEBS Lett. 1996 Jul 29; 390 (3):265-70
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116. Eblen ST, Fautsch MP, Anders RA, Leof EB. Conditional binding to and cell cycle-regulated inhibition of cyclin-dependent kinase complexes by P27(KIP1). Cell Growth Differ. 1995 Aug; 6:915-25.
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117. Fautsch MP, Eblen ST, Anders RA, Burnette RJ, Leof EB. Differential regulation of p34cdc2 and p33cdk2 by transforming growth factor-beta 1 in murine mammary epithelial cells. J Cell Biochem. 1995 Aug; 58 (4):517-26
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118. Eblen ST, Fautsch MP, Burnette RJ, Snyder MR, Leof EB. Dissociation of p34cdc2 complex formation from phosphorylation and histone H1 kinase activity. Can Res. 1995; 55:1994-2000.
     
119. Eblen ST, Fautsch MP, Burnette RJ, Joshi P, Leof EB. Cell cycle-dependent inhibition of p34cdc2 synthesis by transforming growth factor beta 1 in cycling epithelial cells. Cell Growth Differ. 1994 Feb; 5(2):109-16.
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120. Fautsch MP, Thompson MA, Holicky EL, Thompson MA, Schultz PJ, Hallett JB, Wieben ED. Conservation of coding and transcriptional control sequences within the snRNP E protein gene. Genomics. 1992 Dec; 14 (4):883-90
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121. Fautsch MP, Wieben ED. Transcriptional regulation of the small nuclear ribonucleoprotein E protein gene. J Biol Chem. 1991 Dec 5; 34:23288-95.
     
122. Fautsch MP, Wieben ED. Transcriptional regulation of the small nuclear ribonucleoprotein E protein gene. Identification of cis-acting sequences with homology to genes encoding ribosomal proteins. J Biol Chem. 1991 Dec 5; 266 (34):23288-95
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