Publications

1. Zein SE, Tande AJ, Carr CM, Verdoorn JT, Diehn FE, Lahr BD, Kingsbury MJ, Freedman BA, Huddleston PM, Howard MT, Horna P, Berbari EF. The utility of disc space and vertebral body specimens cell count differential for the diagnosis of native vertebral osteomyelitis: a prospective cohort study. Eur J Clin Microbiol Infect Dis. 2024 Oct 2 Epub 2024 Oct 02
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2. Levy HA, Boere P, Randell Z, Bodnar J, Paulik J, Spina NT, Spiker WR, Lawrence BD, Brodke DS, Kurd MF, Rihn JA, Canseco JA, Schroeder GD, Kepler CK, Vaccaro AR, Currier B, Huddleston PM, Nassr AN, Freedman BA, Sebastian AS, Hilibrand AS, Karamian BA. Factors Related to Clinical Performance in Spine Surgery Fellowship: Can We Predict Success. J Am Acad Orthop Surg. 2024 Sep 15; 32 (18):e940-e950 Epub 2024 July 12
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3. Bernatz JT, Goh BC, Skjaerlund JD, Mikula AL, Johnson SE, Bydon M, Fogelson J, Elder B, Huddleston P, Karim M, Nassr A, Sebastian A, Freedman B. Intraoperative Surgeon Assessment of Bone: Correlation to Bone Mineral Density, CT Hounsfield Units, and Vertebral Bone Quality. Spine (Phila Pa 1976). 2024 Aug 15; 49 (16):1125-1129 Epub 2023 Oct 19
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4. Pinter Z, Honig R, Sebastian A, Nassr A, Freedman B, Yaszemski M, Huddleston P 3rd, Berbari E, Currier B. Does Intrawound Vancomycin Decrease Postoperative Surgical Site Infection in Spine Surgery: A Retrospective Case-control Study. Clin Spine Surg. 2024 Jul 1; 37 (6):E264-E268 Epub 2024 Feb 05
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5. Bernatz JT, Pumford A, Goh BC, Pinter ZW, Mikula AL, Michalopoulos GD, Bydon M, Huddleston P, Nassr AN, Freedman BA, Sebastian AS. MRI Vertebral Bone Quality Correlates With Interbody Cage Subsidence After Anterior Cervical Discectomy and Fusion. Clin Spine Surg. 2024 May 1; 37 (4):149-154 Epub 2024 May 02
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6. Tai DBG, Lahr B, Suh GA, Berbari EF, Huddleston PM, Tande AJ. Defeating the Hidden Foe: Antibiotic Therapy and Clinical Outcomes of Cutibacterium acnes Spinal Implant Infections. Open Forum Infect Dis. 2023 Aug; 10 (8):ofad403 Epub 2023 July 24
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7. Kolz JM, Mitchell SA, Elder BD, Sebastian AS, Freedman BA. Sacral Insufficiency Fracture Following Short-Segment Lumbosacral Fusion: Case Series and Review of the Literature. Global Spine J. 2022 Mar; 12 (2):267-277 Epub 2020 Aug 30
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8. Riaz T, Howard M, Diehn F, Tande AJ, Ross C, Huddleston P, Berbari E. Utility of disc space aspirate cell counts and differentials in the diagnosis of native vertebral osteomyelitis. J Bone Jt Infect. 2022; 7(5):213-219. Epub 2022 Oct 20.
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9. Tomov M, Alvi MA, Elminawy M, Currier B, Yaszemski M, Nassr A, Huddleston P, Sebastian A, Bydon M, Freedman B. An Objective and Reliable Method for Identifying Sarcopenia in Lumbar Spine Surgery Patients: Using Morphometric Measurements on Computed Tomography Imaging. Asian Spine J. 2020 Dec; 14 (6):814-820 Epub 2020 May 29
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10. Warner NS, Finnie D, Warner DO, Hooten WM, Mauck KF, Cunningham JL, Gazelka H, Bydon M, Huddleston PM, Habermann EB. The System Is Broken: A Qualitative Assessment of Opioid Prescribing Practices After Spine Surgery. Mayo Clin Proc. 2020 Sep; 95 (9):1906-1915 Epub 2020 July 28
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11. Warner NS, Habermann EB, Hooten WM, Hanson AC, Schroeder DR, St Sauver JL, Huddleston PM, Bydon M, Cunningham JL, Gazelka HM, Warner DO. Association Between Spine Surgery and Availability of Opioid Medication. JAMA Netw Open. 2020 Jun 1; 3 (6):e208974 Epub 2020 June 01
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12. Carlson BC, Hines JT, Robinson WA, Sebastian AS, Greenwood-Quaintance KE, Patel R, Huddleston PM. Implant Sonication versus Tissue Culture for the Diagnosis of Spinal Implant Infection. Spine (Phila Pa 1976). 2020 May 1; 45 (9):E525-E532
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13. Wanderman N, Robinson W, Carlson B, Bydon M, Currier B, Huddleston P, Nassr A, Freedman B. Tranexamic Acid in Thoracic and Lumbar Fusions and Perioperative Blood Loss. Clin Spine Surg. 2019 Dec; 32 (10):E462-E468
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14. McCormick ZL, Lehman VT, Plastaras CT, Walega DR, Huddleston P 3rd, Moussallem C, Geske JR, Verdoorn JT, Kennedy DJ, Maus TP, Carr CM. Low-Pressure Lumbar Provocation Discography According to Spine Intervention Society/International Association for the Study of Pain Standards Does Not Cause Acceleration of Disc Degeneration in Patients With Symptomatic Low Back Pain: A 7-Year Matched Cohort Study. Spine (Phila Pa 1976). 2019 Oct 1; 44 (19):E1161-E1168
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15. Tomov M, Wanderman N, Berbari E, Currier B, Yaszemski M, Nassr A, Huddleston P, Bydon M, Freedman B. An empiric analysis of 5 counter measures against surgical site infections following spine surgery-a pragmatic approach and review of the literature. Spine J. 2019 Feb; 19 (2):267-275 Epub 2018 June 02
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16. Aleem IS, Currier BL, Yaszemski MJ, Poppendeck H, Huddleston P, Eck J, Rhee J, Bydon M, Freedman B, Nassr A. Do Cervical Spine Surgery Patients Recall Their Preoperative Status?: A Cohort Study of Recall Bias in Patient-reported Outcomes. Clin Spine Surg. 2018 Dec; 31 (10):E481-E487
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17. Wanderman N, Carlson B, Robinson W, Bydon M, Yaszemski M, Huddleston P, Freedman B. Does Recombinant Human Bone Morphogenic Protein 2 Affect Perioperative Blood Loss after Lumbar and Thoracic Spinal Fusion? Asian Spine J. 2018 Oct; 12 (5):880-886 Epub 2018 Sept 10
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18. Carlson BC, Robinson WA, Wanderman NR, Nassr AN, Huddleston PM 3rd, Yaszemski MJ, Currier BL, Jeray KJ, Kirk KL, Bunta AD, Murphy S, Patel B, Watkins CM, Sietsema DL, Edwards BJ, Tosi LL, Anderson PA, Freedman BA. The American Orthopaedic Association's Own the Bone(R) database: a national quality improvement project for the treatment of bone health in fragility fracture patients. Osteoporos Int. 2018 Sep; 29 (9):2101-2109 Epub 2018 June 01
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19. Riester SM, Lin Y, Wang W, Cong L, Mohamed Ali AM, Peck SH, Smith LJ, Currier BL, Clark M, Huddleston P, Krauss W, Yaszemski MJ, Morrey ME, Abdel MP, Bydon M, Qu W, Larson AN, van Wijnen AJ, Nassr A. RNA sequencing identifies gene regulatory networks controlling extracellular matrix synthesis in intervertebral disk tissues. J Orthop Res. 2018 May; 36 (5):1356-1369 Epub 2018 Jan 10
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20. Asiedu GB, Lowndes BR, Huddleston PM, Hallbeck S. "The Jackson Table Is a Pain in the...": A Qualitative Study of Providers' Perception Toward a Spinal Surgery Table. J Patient Saf. 2018 Mar; 14 (1):21-26
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21. Tomov M, Tou K, Winkel R, Puffer R, Bydon M, Nassr A, Huddleston P, Yaszemski M, Currier B, Freedman B. Does Subcutaneous Infiltration of Liposomal Bupivacaine Following Single-Level Transforaminal Lumbar Interbody Fusion Surgery Improve Immediate Postoperative Pain Control? Asian Spine J. 2018 Feb; 12 (1):85-93 Epub 2018 Feb 07
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22. Moussallem CD, McCutcheon BA, Clarke MJ, Cui Q, Currier BL, Yaszemski MJ, Huddleston PM, Rose PS, Freedman B, Dekutoski MB, Bydon M, Nassr A. Perioperative complications in open versus percutaneous treatment of spinal fractures in patients with an ankylosed spine. J Clin Neurosci. 2016 Aug; 30:88-92 Epub 2016 Mar 30
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23. Sebastian AS, Currier BL, Clarke MJ, Larson D, Huddleston PM 3rd, Nassr A. Thromboembolic Disease after Cervical Spine Surgery: A Review of 5,405 Surgical Procedures and Matched Cohort Analysis. Global Spine J. 2016 Aug; 6 (5):465-71 Epub 2015 Nov 26
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24. Sebastian A, Huddleston P 3rd, Kakar S, Habermann E, Wagie A, Nassr A. Risk factors for surgical site infection after posterior cervical spine surgery: an analysis of 5,441 patients from the ACS NSQIP 2005-2012. Spine J. 2016 Apr; 16 (4):504-9 Epub 2015 Dec 10
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25. Tescher AN, Rindflesch AB, Youdas JW, Terman RW, Jacobson TM, Douglas LL, Miers AG, Austin CM, Delgado AM, Zins SM, Lahr BD, Pichelmann MA, Heller SF, Huddleston PM 3rd. Comparison of Cervical Range-of-Motion Restriction and Craniofacial Tissue-Interface Pressure With 2 Adjustable and 2 Standard Cervical Collars. Spine (Phila Pa 1976). 2016 Mar; 41 (6):E304-12
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26. Asiedu GB, Lowndes BR, Huddleston PM, Hallbeck S. "The Jackson Table Is a Pain in the...": A Qualitative Study of Providers' Perception Toward a Spinal Surgery Table. J Patient Saf. 2016 Jan 7 Epub 2016 Jan 07
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27. Ozen A, Marmor Y, Rohleder T, Balasubramanian H, Huddleston J, Huddleston P. Optimization and simulation of orthopedic spine surgery cases at Mayo Clinic Manufacturing and Service Operations Management. 2016; 18: (1)157-75.
    
28. Huddleston P. X-Stop Resulted in a Higher Reoperation Rate Than Minimally Invasive Decompression, But Both Decreased Symptoms of Neurogenic Intermittent Claudication in Patients with Lumbar Spinal Stenosis. J Bone Joint Surg Am 2015 Nov 18; 97 (22):1889
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29. Gupta BP, Steckelberg RC, Gullerud RE, Huddleston PM, Kirkland LL, Wright RS, Huddleston JM. Incidence and 1-Year Outcomes of Perioperative Atrial Arrhythmia in Elderly Adults After Hip Fracture Surgery. J Am Geriatr Soc. 2015 Nov; 63 (11):2269-74 Epub 2015 Oct 27
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30. Giambini H, Dragomir-Daescu D, Huddleston PM, Camp JJ, An KN, Nassr A. The Effect of Quantitative Computed Tomography Acquisition Protocols on Bone Mineral Density Estimation. J Biomech Eng. 2015 Nov; 137 (11):114502
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31. Berbari EF, Kanj SS, Kowalski TJ, Darouiche RO, Widmer AF, Schmitt SK, Hendershot EF, Holtom PD, Huddleston PM 3rd, Petermann GW, Osmon DR. Executive Summary: 2015 Infectious Diseases Society of America (IDSA) Clinical Practice Guidelines for the Diagnosis and Treatment of Native Vertebral Osteomyelitis in Adults. Clin Infect Dis. 2015 Sep 15; 61 (6):859-63
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32. Berbari EF, Kanj SS, Kowalski TJ, Darouiche RO, Widmer AF, Schmitt SK, Hendershot EF, Holtom PD, Huddleston PM 3rd, Petermann GW, Osmon DR, Infectious Diseases Society of America America. 2015 Infectious Diseases Society of America (IDSA) Clinical Practice Guidelines for the Diagnosis and Treatment of Native Vertebral Osteomyelitis in Adults. Clin Infect Dis. 2015 Sep 15; 61 (6):e26-46 Epub 2015 July 29
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33. Kremers HM, Nwojo ME, Ransom JE, Wood-Wentz CM, Melton LJ 3rd, Huddleston PM 3rd. Trends in the epidemiology of osteomyelitis: a population-based study, 1969 to 2009. J Bone Joint Surg Am. 2015 May 20; 97(10):837-45.
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34. Linte CA, Camp JJ, Augustine KE, Huddleston PM, Robb RA, Holmes DR III. Estimating pedicle screw fastening strength via a virtual templating platform for spine surgery planning: a retrospective preliminary clinical demonstration Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization. 2015; 3: (4)204-12.
    
35. Gupta A, Kowalski TJ, Osmon DR, Enzler M, Steckelberg JM, Huddleston PM, Nassr A, Mandrekar JM, Berbari EF. Long-term outcome of pyogenic vertebral osteomyelitis: a cohort study of 260 patients. Open Forum Infect Dis. 2014 Dec; 1 (3):ofu107 Epub 2014 Dec 05
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36. Brown DA, Mallory GW, Higgins DM, Abdulaziz M, Huddleston PM, Nassr A, Fogelson JL, Clarke MJ. A cost-effective method for femoral head allograft procurement for spinal arthrodesis: an alternative to commercially available allograft. Spine (Phila Pa 1976). 2014 Jul 1; 39: (15)E902-6.
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37. Linte CA, Camp JJ, Augustine KE, Huddleston PM, Robb RA, Holmes DR III. Virtual estimates of fastening strength for pedicle screw implantation procedures. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2014; 9036:903617.
    
38. Ramos A, Berbari E, Huddleston P. Diagnosis and treatment of Fusobacterium nucleatum discitis and vertebral osteomyelitis: case report and review of the literature. Spine (Phila Pa 1976). 2013 Jan 15; 38 (2):E120-2
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39. Huddleston JM, Gullerud RE, Smither F, Huddleston PM, Larson DR, Phy MP, Melton LJ 3rd, Roger VL. Myocardial infarction after hip fracture repair: a population-based study. J Am Geriatr Soc. 2012 Nov; 60 (11):2020-6 Epub 2012 Oct 30
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40. Gupta BP, Huddleston JM, Kirkland LL, Huddleston PM, Larson DR, Gullerud RE, Burton MC, Rihal CS, Wright RS. Clinical presentation and outcome of perioperative myocardial infarction in the very elderly following hip fracture surgery. J Hosp Med. 2012 Nov-Dec; 7 (9):713-6 Epub 2012 Sept 06
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41. Arendt BK, Walters DK, Wu X, Tschumper RC, Huddleston PM, Henderson KJ, Dispenzieri A, Jelinek DF. Increased expression of extracellular matrix metalloproteinase inducer (CD147) in multiple myeloma: role in regulation of myeloma cell proliferation. Leukemia. 2012 Oct; 26 (10):2286-96 Epub 2012 Mar 30
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42. Tschumper RC, Asmann YW, Hossain A, Huddleston PM, Wu X, Dispenzieri A, Eckloff BW, Jelinek DF. Comprehensive assessment of potential multiple myeloma immunoglobulin heavy chain V-D-J intraclonal variation using massively parallel pyrosequencing. Oncotarget. 2012 Apr; 3 (4):502-13
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43. Eastlack RK, Kesman TJ, Patel R, Huddleston PM. Infection not associated with use of human musculoskeletal tissue allografts. Cell Tissue Bank. 2012 Mar; 13(1):47-51. Epub 2010 Sep 29.
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44. Linte CA, Augustine KE, Huddleston PM, Stans AA, Holmes DR III, Robb RA. Enhanced planning of interventions for spinal deformity correction using virtual modeling and visualization techniques. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 2012; 7264 LNCS:93-105.
    
45. Lehman RA Jr, Huddleston P, Yaszemski M. Axial spine injuries in the current conflicts in Iraq and Afghanistan. J Am Acad Orthop Surg. 2012; 20:S13-7.
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46. Walters DK, Wu X, Tschumper RC, Wu X, Arendt BK, Huddleston PM, Henderson KJ, Dispenzieri A, Jelinek DF. Evidence for ongoing DNA damage in multiple myeloma cells as revealed by constitutive phosphorylation of H2AX. Leukemia. 2011 Aug; 25 (8):1344-53 Epub 2011 May 13
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47. Batsis JA, Naessens JM, Keegan MT, Huddleston PM, Wagie AE, Huddleston JM. Body mass index and the impact on hospital resource use in patients undergoing total knee arthroplasty. J Arthroplasty. 2010 Dec; 25(8):1250-7.e1. Epub 2010 Feb 19.
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48. Gutierrez A Jr, Tschumper RC, Wu X, Shanafelt TD, Eckel-Passow J, Huddleston PM 3rd, Slager SL, Kay NE, Jelinek DF. LEF-1 is a prosurvival factor in chronic lymphocytic leukemia and is expressed in the preleukemic state of monoclonal B-cell lymphocytosis. Blood. 2010 Oct 21; 116 (16):2975-83 Epub 2010 July 01
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49. Mihalcik SA, Huddleston PM 3rd, Wu X, Jelinek DF. The structure of the TNFRSF13C promoter enables differential expression of BAFF-R during B cell ontogeny and terminal differentiation. J Immunol. 2010 Jul 15; 185 (2):1045-54 Epub 2010 June 16
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50. Sampedro MF, Huddleston PM, Piper KE, Karau MJ, Dekutoski MB, Yaszemski MJ, Currier BL, Mandrekar JN, Osmon DR, McDowell A, Patrick S, Steckelberg JM, Patel R. A biofilm approach to detect bacteria on removed spinal implants. Spine (Phila Pa 1976). 2010 May 20; 35 (12):1218-24
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51. Piper KE, Fernandez-Sampedro M, Steckelberg KE, Mandrekar JN, Karau MJ, Steckelberg JM, Berbari EF, Osmon DR, Hanssen AD, Lewallen DG, Cofield RH, Sperling JW, Sanchez-Sotelo J, Huddleston PM, Dekutoski MB, Yaszemski M, Currier B, Patel R. C-reactive protein, erythrocyte sedimentation rate and orthopedic implant infection. PLoS One. 2010 Feb 22; 5 (2):e9358
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52. Mikhael MM, Huddleston PM, Nassr A. Postoperative culture positive surgical site infections after the use of irradiated allograft, nonirradiated allograft, or autograft for spinal fusion. Spine (Phila Pa 1976). 2009 Oct 15; 34 (22):2466-8
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53. Batsis JA, Huddleston JM, Melton LJ III, Huddleston PM, Larson DR, Gullerud RE, McMahon MM. Body mass index (BMI) and risk of noncardiac postoperative medical complications in elderly hip fracture patients: a population-based study. J Hosp Med. 2009 Oct; 4(8):E1-9.
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54. Hongo M, Gay RE, Zhao KD, Ilharreborde B, Huddleston PM, Berglund LJ, An KN, Zhao C. Junction kinematics between proximal mobile and distal fused lumbar segments: biomechanical analysis of pedicle and hook constructs. Spine J. 2009 Oct; 9(10):846-53. Epub 2009 Aug 05.
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55. Batsis JA, Naessens JM, Keegan MT, Wagie AE, Huddleston PM, Huddleston JM. Impact of body mass on hospital resource use in total hip arthroplasty. Public Health Nutr. 2009 Aug; 12(8):1122-32. Epub 2009 Mar 12.
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56. Popa AS, Rabinstein AA, Huddleston PM, Larson DR, Gullerud RE, Huddleston JM. Predictors of ischemic stroke after hip operation: a population-based study. J Hosp Med. 2009 May; 4 (5):298-303
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57. Batsis JA, Huddleston JM, Melton LJ 4th, Huddleston PM, Lopez-Jimenez F, Larson DR, Gullerud RE, McMahon MM. Body mass index and risk of adverse cardiac events in elderly patients with hip fracture: a population-based study. J Am Geriatr Soc. 2009 Mar; 57(3):419-26. Epub 2009 Jan 16.
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58. Mikhael MM, Bach HG, Huddleston PM, Maus TP, Berbari EF. Multilevel diskitis and vertebral osteomyelitis after diskography. Orthopedics. 2009 Jan; 32 (1):60
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59. Batsis JA, Naessens JM, Keegan MT, Huddleston PM, Wagie AE, Huddleston JM. Cost savings of hip arthroplasty patients on specialized orthopedic surgery units. Am J Orthop (Belle Mead NJ). 2009 Jan; 38: (1)E5-11.
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60. Unruh KP, Camp CL, Zietlow SP, Huddleston PM. Anatomical variations of the iliolumbar vein with application to the anterior retroperitoneal approach to the lumbar spine: a cadaver study. Clin Anat. 2008 Oct; 21(7):666-73.
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61. Mikhael MM, Huddleston PM, Zobitz ME, Chen Q, Zhao KD, An KN. Mechanical strength of bone allografts subjected to chemical sterilization and other terminal processing methods. J Biomech. 2008 Sep 18; 41(13):2816-20. Epub 2008 Aug 28.
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62. Batsis JA, Naessens JM, Keegan MT, Huddleston PM, Wagie AE, Huddleston JM. Resource utilization of total knee arthroplasty patients cared for on specialty orthopedic surgery units. J Hosp Med. 2008 May; 3(3):218-27.
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63. Ball B, Huddleston PM. Monitoring during lumbar stenosis and fusion surgery. Handbook of Clinical Neurophysiology. 2008; 8(C):678-88.
    
64. Kowalski TJ, Berbari EF, Huddleston PM, Steckelberg JM, Osmon DR. Propionibacterium acnes vertebral osteomyelitis: seek and ye shall find? Clin Orthop Relat Res. 2007 Aug; 461:25-30.
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65. Batsis JA, Phy MP, Melton LJ 3rd, Schleck CD, Melton LJ 3rd, Larson DR, Huddleston PM, Huddleston JM. Effects of a hospitalist care model on mortality of elderly patients with hip fractures. J Hosp Med. 2007 Jul; 2 (4):219-25
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66. Kowalski TJ, Layton KF, Berbari EF, Steckelberg JM, Huddleston PM, Wald JT, Osmon DR. Follow-up MR imaging in patients with pyogenic spine infections: lack of correlation with clinical features. AJNR Am J Neuroradiol. 2007 Apr; 28 (4):693-9
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67. Kowalski TJ, Berbari EF, Huddleston PM, Steckelberg JM, Mandrekar JN, Osmon DR. The management and outcome of spinal implant infections: contemporary retrospective cohort study. Clin Infect Dis. 2007 Apr 1; 44(7):913-20.
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68. Jones DB, Huddleston PM, Zobitz ME, Stuart MJ. Mechanical properties of patellar tendon allografts subjected to chemical sterilization. Arthroscopy. 2007 Apr; 23(4):400-4.
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69. Kowalski TJ, Berbari EF, Huddleston PM, Steckelberg JM, Osmon DR. Do follow-up imaging examinations provide useful prognostic information in patients with spine infection? Clin Infect Dis. 2006 Jul 15; 43 (2):172-9 Epub 2006 June 05
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70. Phy MP, Vanness DJ, Melton LJ 3rd, Long KH, Melton LJ, Schleck CD, Larson DR, Huddleston PM, Huddleston JM. Effects of a hospitalist model on elderly patients with hip fracture. Arch Intern Med. 2005 Apr 11; 165 (7):796-801
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71. Prpa B, Huddleston PM, An KN, Wood MB. Revascularization of nerve grafts: a qualitative and quantitative study of the soft-tissue bed contributions to blood flow in canine nerve grafts. J Hand Surg Am. 2002 Nov; 27(6):1041-7.
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72. Huddleston PM, Steckelberg JM, Hanssen AD, Rouse MS, Bolander ME, Patel R. Ciprofloxacin inhibition of experimental fracture healing. J Bone Joint Surg Am. 2000 Feb; 82 (2):161-73
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73. Huddleston PM. The essentials of orthopedic surgery. Mayo Clin Proc. 1999 Nov.
    
74. Huddleston HT, Dunnihoo DR, Huddleston PM 3rd, Meyers PC Sr. Magnetic resonance imaging of defects in DeLancey's vaginal support levels I, II, and III. Am J Obstet Gynecol ; discussion 1782-4. 1995 Jun; 172: (6)1778-82.
    
75. Huddleston HT, Dunnihoo DR, Huddleston PM, Lemieux JG. Triangles of paravaginal defects. Int Urogynecol J. 1994; 5:287-90.