Publications

1. Ninomiya M, Inoue J, Krueger EW, Chen J, Cao H, Masamune A, McNiven MA. The Exosome-Associated Tetraspanin CD63 Contributes to the Efficient Assembly and Infectivity of the Hepatitis B Virus. Hepatol Commun. 2021 Jul; 5 (7):1238-1251 Epub 2021 Mar 31
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2. Cao H, Qiang L, Chen J, Johnson KM, McNiven MA, Razidlo GL. Synergistic metalloproteinase-based remodeling of matrix by pancreatic tumor and stromal cells. PLoS One. 2021; 16 (3):e0248111 Epub 2021 Mar 19
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3. Li Z, Weller SG, Drizyte-Miller K, Chen J, Krueger EW, Mehall B, Casey CA, Cao H, McNiven MA. Maturation of Lipophagic Organelles in Hepatocytes Is Dependent Upon a Rab10/Dynamin-2 Complex. Hepatology. 2020 Aug; 72 (2):486-502 Epub 2020 Mar 25
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4. Drizyte-Miller K, Chen J, Cao H, Schott MB, McNiven MA. The small GTPase Rab32 resides on lysosomes to regulate mTORC1 signaling. J Cell Sci. 2020 Jun 11; 133 (11) Epub 2020 June 11
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5. Burton KM, Cao H, Chen J, Qiang L, Krueger EW, Johnson KM, Bamlet WR, Zhang L, McNiven MA, Razidlo GL. Dynamin 2 interacts with alpha-actinin 4 to drive tumor cell invasion. Mol Biol Cell. 2020 Mar 15; 31 (6):439-451 Epub 2020 Jan 22
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6. Cao H, Krueger EW, Chen J, Drizyte-Miller K, Schulz ME, McNiven MA. The anti-viral dynamin family member MxB participates in mitochondrial integrity. Nat Commun. 2020 Feb 26; 11 (1):1048
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7. Qiang L, Cao H, Chen J, Weller SG, Krueger EW, Zhang L, Razidlo GL, McNiven MA. Pancreatic tumor cell metastasis is restricted by MT1-MMP binding protein MTCBP-1. J Cell Biol. 2019 Jan 7; 218 (1):317-332 Epub 2018 Nov 28
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8. Zhu S, Zhang X, Weichert-Leahey N, Dong Z, Zhang C, Lopez G, Tao T, He S, Wood AC, Oldridge D, Ung CY, van Ree JH, Khan A, Salazar BM, Lummertz da Rocha E, Zimmerman MW, Guo F, Cao H, Hou X, Weroha SJ, Perez-Atayde AR, Neuberg DS, Meves A, McNiven MA, van Deursen JM, Li H, Maris JM, Look AT. LMO1 Synergizes with MYCN to Promote Neuroblastoma Initiation and Metastasis. Cancer Cell. 2017 Sep 11; 32(3):310-323.e5. Epub 2017 Aug 31.
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9. Cao H, Schroeder B, Chen J, Schott MB, McNiven MA. The Endocytic Fate of the Transferrin Receptor Is Regulated by c-Abl Kinase. J Biol Chem. 2016 Aug 5; 291 (32):16424-37 Epub 2016 May 24
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10. Cao H, Eppinga RD, Razidlo GL, Krueger EW, Chen J, Qiang L, McNiven MA. Stromal fibroblasts facilitate cancer cell invasion by a novel invadopodia-independent matrix degradation process. Oncogene. 2016 Mar 3; 35 (9):1099-1110 Epub 2015 May 18
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11. Inoue J, Krueger EW, Chen J, Cao H, Ninomiya M, McNiven MA. HBV secretion is regulated through the activation of endocytic and autophagic compartments mediated by Rab7 stimulation. J Cell Sci. 2015 May 1; 128 (9):1696-706 Epub 2015 Mar 13
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12. Wu Q, Kohli M, Bergen HR 3rd, Cheville JC, Karnes RJ, Cao H, Young CY, Tindall DJ, McNiven MA, Donkena KV. Preclinical evaluation of the supercritical extract of azadirachta indica (neem) leaves in vitro and in vivo on inhibition of prostate cancer tumor growth. Mol Cancer Ther. 2014 May; 13 (5):1067-77 Epub 2014 Mar 27
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13. Eppinga RD, Krueger EW, Weller SG, Zhang L, Cao H, McNiven MA. Increased expression of the large GTPase dynamin 2 potentiates metastatic migration and invasion of pancreatic ductal carcinoma. Oncogene. 2012 Mar 8; 31: (10)1228-41.
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14. Cao H, Krueger EW, McNiven MA. Hepatocytes internalize trophic receptors at large endocytic "Hot Spots". Hepatology. 2011 Nov; 54 (5):1819-29
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15. Chi S, Cao H, Wang Y, McNiven MA. Recycling of the epidermal growth factor receptor is mediated by a novel form of the clathrin adaptor protein Eps15. J Biol Chem. 2011 Oct 7; 286 (40):35196-208 Epub 2011 Aug 08
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16. Wang Y, Cao H, Chen J, McNiven MA. A direct interaction between the large GTPase dynamin-2 and FAK regulates focal adhesion dynamics in response to active Src. Mol Biol Cell. 2011 May; 22 (9):1529-38 Epub 2011 Mar 16
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17. Weller SG, Capitani M, Cao H, Micaroni M, Luini A, Sallese M, McNiven MA. Src kinase regulates the integrity and function of the Golgi apparatus via activation of dynamin 2. Proc Natl Acad Sci U S A. 2010 Mar 30; 107 (13):5863-8 Epub 2010 Mar 15
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18. Cao H, Chen J, Krueger EW, McNiven MA. SRC-mediated phosphorylation of dynamin and cortactin regulates the "constitutive" endocytosis of transferrin. Mol Cell Biol. 2010 Feb; 30 (3):781-92 Epub 2009 Dec 07
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19. Orlichenko L, Weller SG, Cao H, Krueger EW, Awoniyi M, Beznoussenko G, Buccione R, McNiven MA. Caveolae mediate growth factor-induced disassembly of adherens junctions to support tumor cell dissociation. Mol Biol Cell. 2009 Oct; 20 (19):4140-52 Epub 2009 July 29
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20. Chi S, Cao H, Chen J, McNiven MA. Eps15 mediates vesicle trafficking from the trans-Golgi network via an interaction with the clathrin adaptor AP-1. Mol Biol Cell. 2008 Aug; 19 (8):3564-75 Epub 2008 June 04
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21. Cao H, Chen J, Awoniyi M, Henley JR, McNiven MA. Dynamin 2 mediates fluid-phase micropinocytosis in epithelial cells. J Cell Sci. 2007 Dec 1; 120: (Pt 23)4167-77.
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22. Cao H, Weller S, Orth JD, Chen J, Huang B, Chen JL, Stamnes M, McNiven MA. Actin and Arf1-dependent recruitment of a cortactin-dynamin complex to the Golgi regulates post-Golgi transport. Nat Cell Biol. 2005 May; 7 (5):483-92 Epub 2005 Apr 10
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23. Yao Q, Chen J, Cao H, Orth JD, McCaffery JM, Stan RV, McNiven MA. Caveolin-1 interacts directly with dynamin-2. J Mol Biol. 2005 Apr 29; 348: (2)491-501.
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24. Thompson HM, Cao H, Chen J, Euteneuer U, McNiven MA. Dynamin 2 binds gamma-tubulin and participates in centrosome cohesion. Nat Cell Biol. 2004 Apr; 6(4):335-42. Epub 2004 Mar 14.
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25. Chen XM, Huang BQ, Splinter PL, Cao H, Zhu G, McNiven MA, LaRusso NF. Cryptosporidium parvum invasion of biliary epithelia requires host cell tyrosine phosphorylation of cortactin via c-Src. Gastroenterology. 2003 Jul; 125 (1):216-28
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26. Gray NW, Fourgeaud L, Huang B, Chen J, Cao H, Oswald BJ, Hemar A, McNiven MA. Dynamin 3 is a component of the postsynapse, where it interacts with mGluR5 and Homer. Curr Biol. 2003 Mar 18; 13 (6):510-5
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27. Cao H, Orth JD, Chen J, Weller SG, Heuser JE, McNiven MA. Cortactin is a component of clathrin-coated pits and participates in receptor-mediated endocytosis. Mol Cell Biol. 2003 Mar; 23 (6):2162-70
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28. Krueger EW, Orth JD, Cao H, McNiven MA. A dynamin-cortactin-Arp2/3 complex mediates actin reorganization in growth factor-stimulated cells. Mol Biol Cell. 2003 Mar; 14 (3):1085-96
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29. Abdulkarim AS, Cao H, Huang B, McNiven MA. The large GTPase dynamin is required for hepatitis B virus protein secretion from hepatocytes. J Hepatol. 2003 Jan; 38 (1):76-83
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30. Orth JD, Krueger EW, Cao H, McNiven MA. The large GTPase dynamin regulates actin comet formation and movement in living cells. Proc Natl Acad Sci U S A. 2002 Jan 8; 99 (1):167-72
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31. Cao H, Thompson H, Krueger EW, Thompson H, McNiven M, McNiven M. Use of green fluorescent protein (GFP) to study cellular dynamics. Constructing GFP-tagged motor enzymes. Methods Mol Biol. 2001; 161:165-87
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32. McNiven MA, Kim L, Krueger EW, Orth JD, Cao H, Wong TW. Regulated interactions between dynamin and the actin-binding protein cortactin modulate cell shape. J Cell Biol. 2000 Oct 2; 151 (1):187-98
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33. Ochoa GC, Slepnev VI, Neff L, Ringstad N, Takei K, Daniell L, Kim W, Cao H, McNiven M, Baron R, De Camilli P. A functional link between dynamin and the actin cytoskeleton at podosomes. J Cell Biol. 2000 Jul 24; 150(2):377-89.
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34. Cao H, Thompson HM, Krueger EW, McNiven MA. Disruption of Golgi structure and function in mammalian cells expressing a mutant dynamin. J Cell Sci. 2000 Jun; 113 ( Pt 11):1993-2002
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35. McNiven MA, Cao H, Pitts KR, Yoon Y. The dynamin family of mechanoenzymes: pinching in new places. Trends Biochem Sci. 2000 Mar; 25 (3):115-20
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36. Henley JR, Cao H, McNiven MA. Participation of dynamin in the biogenesis of cytoplasmic vesicles. FASEB J. 1999 Dec; 13 Suppl 2:S243-7
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37. Cao H, Chan , W., Du , Z.. Immunohistochemical observation on hepatitis B complicated with delta factor infection Tianjin Medical Journal.1999;13:243-247.
    
38. Cao H, Garcia F, McNiven MA. Differential distribution of dynamin isoforms in mammalian cells. Mol Biol Cell. 1998 Sep; 9 (9):2595-609
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39. Jones SM, Howell KE, Henley JR, Cao H, McNiven MA. Role of dynamin in the formation of transport vesicles from the trans-Golgi network. Science. 1998 Jan 23; 279 (5350):573-7
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40. Cao H, Mattison , J., Zhao , Y., Joki , N., Grasso , M., Chang , N.S.. Regulation of tumor necrosis factor-and Fas-mediated apoptotic cell death by a novel cDNA TR2L. Biochem Biophys Res Commun..1996;227:(1)266-72.
    
41. Wei BY, Cao H, Pan S, David CS. Sequence analysis of MHC class II Eb cDNAs from H2r and H2p haplotypes. Immunogenetics. 1996; 44 (3):231-2
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42. Zanelli E, Zhou P, Cao H, Smart MK, David CS. Genetic polymorphism of the mouse major histocompatibility complex-associated proteasome subunit Lmp7. Immunogenetics. 1995; 41 (4):251-4
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43. Zhou P, Cao H, Smart M, David C. Molecular basis of genetic polymorphism in major histocompatibility complex-linked proteasome gene (Lmp-2). Proc Natl Acad Sci U S A. 1993 Apr 1; 90 (7):2681-4
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44. Zanelli E, Zhou P, Cao H, Smart MK, David CS. Genomic organization and tissue expression of the mouse proteasome gene Lmp-7. Immunogenetics. 1993; 38 (6):400-7
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45. Cao H, Chan , W., Du , Z.. HDV infection complication with severe hepatitis B study Journal of Clinical and Experimental Pathology.1991;3:(7)195.
    
46. Cao H, Chan , W, Du , Z. HDV 9delta factor) infection complicated with sub acute fulminate hepatitis B--A Morphological and immunohistochemical observation Chinese Medical Journal.1990;103:(7)619.