Publications

  1. Khurram OU, Kantor-Gerber MJ, Mantilla CB, Sieck GC. Hypercapnia impacts neural drive and timing of diaphragm neuromotor control. J Neurophysiol. 2024 Nov 16 [Epub ahead of print]
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  2. Jahanian S, Pareja-Cajiao M, Gransee HM, Sieck GC, Mantilla CB. Autophagy markers LC3 and p62 in aging lumbar motor neurons. Exp Gerontol. 2024 Sep; 194:112483 Epub 2024 June 18
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  3. Khurram OU, Mantilla CB, Sieck GC. Identification of eupneic breathing using machine learning. J Neurophysiol. 2024 Sep 1; 132 (3):678-684 Epub 2024 July 25
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  4. Porter SB, Martin-McGrew Y, Njathi-Ori C, Bruns DL, LeMahieu AM, Mantilla CB, Milam AJ, Ladlie BL. Postanesthesia Care Unit and Anesthetic Management Outcomes Among Patients Undergoing Noncardiac Surgery: Differences by Race and Ethnicity. J Perianesth Nurs. 2024 Aug; 39 (4):659-665 Epub 2024 Feb 05
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  5. Khurram OU, Fogarty MJ, Zhan WZ, Mantilla CB, Sieck GC. Assessing Functional Recovery of Eupneic Diaphragm Activity Following Unilateral Cervical Spinal Cord Injury in Rats. J Vis Exp. 2024 Jun 14; (208) Epub 2024 June 14
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  6. Fogarty MJ, Zhan WZ, Mantilla CB, Sieck GC. Cervical spinal cord hemisection impacts sigh and the respiratory reset in male rats. Physiol Rep. 2024 Mar; 12 (5):e15973
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  7. Azzag K, Gransee HM, Magli A, Yamashita AMS, Tungtur S, Ahlquist A, Zhan WZ, Onyebu C, Greising SM, Mantilla CB, Perlingeiro RCR. Enhanced Diaphragm Muscle Function upon Satellite Cell Transplantation in Dystrophic Mice. Int J Mol Sci. 2024 Feb 21; 25 (5)
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  8. Saldarriaga CA, Alatout MH, Khurram OU, Gransee HM, Sieck GC, Mantilla CB. Chloroquine impairs maximal transdiaphragmatic pressure generation in old mice. J Appl Physiol (1985). 2023 Nov 1; 135 (5):1126-1134 Epub 2023 Oct 12
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  9. Khurram OU, Mantilla CB, Sieck GC. Neuromotor control of spontaneous quiet breathing in awake rats evaluated by assessments of diaphragm EMG stationarity. J Neurophysiol. 2023 Nov 1; 130 (5):1344-1357 Epub 2023 Oct 25
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  10. Fogarty MJ, Rana S, Mantilla CB, Sieck GC. Size-dependent differences in mitochondrial volume density in phrenic motor neurons. J Appl Physiol (1985). 2023 Jun 1; 134 (6):1332-1340 Epub 2023 Apr 06
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  11. Mantilla CB, Ermilov LG, Greising SM, Gransee HM, Zhan WZ, Sieck GC. Electrophysiological effects of BDNF and TrkB signaling at type-identified diaphragm neuromuscular junctions. J Neurophysiol. 2023 Apr 1; 129 (4):781-792 Epub 2023 Mar 08
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  12. Gonzalez Porras MA, Gransee HM, Denton TT, Shen D, Webb KL, Brinker CJ, Noureddine A, Sieck GC, Mantilla CB. CTB-targeted protocells enhance ability of lanthionine ketenamine analogs to induce autophagy in motor neuron-like cells. Sci Rep. 2023 Feb 13; 13 (1):2581
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  13. Brown AD, Fogarty MJ, Davis LA, Dasgupta D, Mantilla CB, Sieck GC. Mitochondrial adaptations to inactivity in diaphragm muscle fibers. J Appl Physiol (1985). 2022 Jul 1; 133 (1):191-204 Epub 2022 June 09
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  14. Rana S, Zhan WZ, Sieck GC, Mantilla CB. Cervical spinal hemisection alters phrenic motor neuron glutamatergic mRNA receptor expression. Exp Neurol. 2022 Jul; 353:114030 Epub 2022 Mar 02
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  15. Khurram OU, Gransee HM, Sieck GC, Mantilla CB. Automated evaluation of respiratory signals to provide insight into respiratory drive. Respir Physiol Neurobiol. 2022 Jun; 300:103872 Epub 2022 Feb 24
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  16. Gransee HM, Gonzalez Porras MA, Denton TT, Shen D, Sieck GC, Mantilla CB. Induction of Autophagy in Motor Neurons with Lanthionine Ketenamine Analogs. FASEB J. 2022 May; 36 Suppl 1
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  17. Ducaji EC, Sang J, Pareja-Cajiao M, Gransee HM, Sieck GC, Mantilla CB. Age-Related Autophagy Impairment in Cervical and Lumbar Motor Neurons. FASEB J. 2022 May; 36 Suppl 1
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  18. Davis LA, Brown AD, Fogarty MJ, Mantilla CB, Sieck GC. Aging Selectively Reduces Mitochondrial Volume Density and Respiratory Capacity in Type IIx/IIb Diaphragm Muscle Fibers. FASEB J. 2022 May; 36 Suppl 1
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  19. Khurram OU, Gransee HM, Sieck GC, Mantilla CB. Automated Evaluation of Respiratory Signals to Provide Insight Into Respiratory Drive. FASEB J. 2022 May; 36 Suppl 1
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  20. Pareja-Cajiao M, Barrera MA, Ducaji RA, Gransee HM, Hellyer NJ, Sieck GC, Mantilla CB. Autophagy Impairment and Sarcopenia in Type-Identified Muscle Fibers of Aging Extensor Digitorum Longus Muscle. FASEB J. 2022 May; 36 Suppl 1
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  21. Hernandez-Vizcarrondo GA, Brown AD, Davis LA, Fogarty MJ, Mantilla CB, Sieck GC. Fiber Type Differences in SDHmax and Mitochondrial Volume Density between Diaphragm and Tibialis Anterior Muscles. FASEB J. 2022 May; 36 Suppl 1
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  22. Davis LA, Forero L, Hernandez-Vizcarrondo G, Han YS, Mantilla CB, Sieck GC. Force and Shortening Velocity are Reduced in 24-month Fischer 344 Rats. FASEB J. 2022 May; 36 Suppl 1
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  23. Brown AD, Fogarty MJ, Dasgupta D, Davis LA, Mantilla CB, Sieck GC. Mitochondria Adapt to Diaphragm Muscle Inactivity Imposed by Cervical Spinal Cord Injury. FASEB J. 2022 May; 36 Suppl 1
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  24. Johnson RL, Frank RD, Abdel MP, Habermann EB, Chamberlain AM, Mantilla CB. Frailty Transitions One Year After Total Joint Arthroplasty: A Cohort Study. J Arthroplasty. 2022 Jan; 37 (1):10-18.e2 Epub 2021 Sept 01
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  25. Fogarty MJ, Khurram OU, Mantilla CB, Sieck GC. Brain derived neurotrophic factor/tropomyosin related kinase B signaling impacts diaphragm neuromuscular transmission in a novel rat chemogenetic model. Front Cell Neurosci. 2022; 16:1025463 Epub 2022 Oct 28
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  26. Memtsoudis SG, Cozowicz C, Bekeris J, Bekere D, Liu J, Soffin EM, Mariano ER, Johnson RL, Go G, Hargett MJ, Lee BH, Wendel P, Brouillette M, Kim SJ, Baaklini L, Wetmore DS, Hong G, Goto R, Jivanelli B, Athanassoglou V, Argyra E, Barrington MJ, Borgeat A, De Andres J, El-Boghdadly K, Elkassabany NM, Gautier P, Gerner P, Gonzalez Della Valle A, Goytizolo E, Guo Z, Hogg R, Kehlet H, Kessler P, Kopp S, Lavand'homme P, Macfarlane A, MacLean C, Mantilla C, McIsaac D, McLawhorn A, Neal JM, Parks M, Parvizi J, Peng P, Pichler L, Poeran J, Poultsides L, Schwenk ES, Sites BD, Stundner O, Sun EC, Viscusi E, Votta-Velis EG, Wu CL, YaDeau J, Sharrock NE. Peripheral nerve block anesthesia/analgesia for patients undergoing primary hip and knee arthroplasty: recommendations from the International Consensus on Anesthesia-Related Outcomes after Surgery (ICAROS) group based on a systematic review and meta-analysis of current literature. Reg Anesth Pain Med. 2021 Nov; 46 (11):971-985 Epub 2021 Aug 25
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  27. Laporta ML, Kruthiventi SC, Mantilla CB, Johnson RL, Sprung J, Portner ER, Schroeder DR, Weingarten TN. Three Risk Stratification Tools and Postoperative Pneumonia After Noncardiothoracic Surgery. Am Surg. 2021 Aug; 87(8):1207-1213. Epub 2020 Dec 19.
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  28. Sieck GC, Gransee HM, Zhan WZ, Mantilla CB. Acute intrathecal BDNF enhances functional recovery after cervical spinal cord injury in rats. J Neurophysiol. 2021 Jun 1; 125 (6):2158-2165 Epub 2021 May 05
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  29. Pareja-Cajiao M, Gransee HM, Sieck GC, Mantilla CB. TrkB signaling contributes to transdiaphragmatic pressure generation in aged mice. J Neurophysiol. 2021 Apr 1; 125 (4):1157-1163 Epub 2021 Feb 17
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  30. Fogarty MJ, Rana S, Mantilla CB, Sieck GC. Quantifying mitochondrial volume density in phrenic motor neurons. J Neurosci Methods. 2021 Apr 1; 353:109093 Epub 2021 Feb 04
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  31. Johnson RL, Habermann EB, Johnson MQ, Abdel MP, Chamberlain AM, Mantilla CB. How Is Surgical Risk Best Assessed? A Cohort Comparison of Measures in Total Joint Arthroplasty. J Arthroplasty. 2021 Mar; 36 (3):851-856.e3 Epub 2020 Oct 01
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  32. Dumitrascu CI, Warner NS, Stewart TM, Amundson AW, Bruns DL, Hanson AC, Schulte PJ, Smith MM, Brown MJ, Niesen AD, Mantilla CB, Warner MA. Peripheral Nerve Blockade with Combined Standard and Liposomal Bupivacaine in Major Lower-Extremity Amputation. Pain Pract. 2021 Mar; 21 (3):299-307 Epub 2020 Nov 04
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  33. Pareja-Cajiao M, Gransee HM, Stowe JM, Rana S, Sieck GC, Mantilla CB. Age-related impairment of autophagy in cervical motor neurons. Exp Gerontol. 2021 Feb; 144:111193 Epub 2020 Dec 05
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  34. Rana S, Zhan WZ, Mantilla CB, Sieck GC. Disproportionate loss of excitatory inputs to smaller phrenic motor neurons following cervical spinal hemisection. J Physiol. 2020 Oct; 598 (20):4693-4711 Epub 2020 Aug 19
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  35. Johnson RL, Frank RD, Habermann EB, Chamberlain AM, Abdel MP, Schroeder DR, Mantilla CB. Neuraxial anesthesia is associated with improved survival after total joint arthroplasty depending on frailty: a cohort study. Reg Anesth Pain Med. 2020 Jun; 45 (6):405-411 Epub 2020 Apr 07
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  36. Rana S, Sieck GC, Mantilla CB. Heterogeneous glutamatergic receptor mRNA expression across phrenic motor neurons in rats. J Neurochem. 2020 Jun; 153 (5):586-598 Epub 2019 Oct 17
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  37. Pareja-Cajiao M, Gransee HM, Cole NA, Sieck GC, Mantilla CB. Inhibition of TrkB kinase activity impairs transdiaphragmatic pressure generation. J Appl Physiol (1985). 2020 Feb 1; 128 (2):338-344 Epub 2020 Jan 16
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  38. Vang P, Vasdev A, Zhan WZ, Gransee HM, Sieck GC, Mantilla CB. Diaphragm muscle sarcopenia into very old age in mice. Physiol Rep. 2020 Jan; 8 (1):e14305
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  39. Fogarty MJ, Marin Mathieu N, Mantilla CB, Sieck GC. Aging reduces succinate dehydrogenase activity in rat type IIx/IIb diaphragm muscle fibers. J Appl Physiol (1985). 2020 Jan 1; 128 (1):70-77 Epub 2019 Nov 27
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  40. Johnson RL, Abdel MP, Frank RD, Chamberlain AM, Habermann EB, Mantilla CB. Frailty Index Is Associated With Periprosthetic Fracture and Mortality After Total Knee Arthroplasty. Orthopedics. 2019 Nov 1; 42 (6):335-343 Epub 2019 Aug 14
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  41. Rana S, Mantilla CB, Sieck GC. Glutamatergic input varies with phrenic motor neuron size. J Neurophysiol. 2019 Oct 1; 122 (4):1518-1529 Epub 2019 Aug 07
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  42. Memtsoudis SG, Cozowicz C, Bekeris J, Bekere D, Liu J, Soffin EM, Mariano ER, Johnson RL, Hargett MJ, Lee BH, Wendel P, Brouillette M, Go G, Kim SJ, Baaklini L, Wetmore D, Hong G, Goto R, Jivanelli B, Argyra E, Barrington MJ, Borgeat A, De Andres J, Elkassabany NM, Gautier PE, Gerner P, Gonzalez Della Valle A, Goytizolo E, Kessler P, Kopp SL, Lavand'Homme P, MacLean CH, Mantilla CB, MacIsaac D, McLawhorn A, Neal JM, Parks M, Parvizi J, Pichler L, Poeran J, Poultsides LA, Sites BD, Stundner O, Sun EC, Viscusi ER, Votta-Velis EG, Wu CL, Ya Deau JT, Sharrock NE. Anaesthetic care of patients undergoing primary hip and knee arthroplasty: consensus recommendations from the International Consensus on Anaesthesia-Related Outcomes after Surgery group (ICAROS) based on a systematic review and meta-analysis. Br J Anaesth. 2019 Sep; 123 (3):269-287 Epub 2019 July 24
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  43. Fogarty MJ, Gonzalez Porras MA, Mantilla CB, Sieck GC. Diaphragm neuromuscular transmission failure in aged rats. J Neurophysiol. 2019 Jul 1; 122 (1):93-104 Epub 2019 May 01
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  44. Fogarty MJ, Mantilla CB, Sieck GC. Impact of sarcopenia on diaphragm muscle fatigue. Exp Physiol. 2019 Jul; 104 (7):1090-1099 Epub 2019 Apr 22
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  45. Gonzalez Porras MA, Fogarty MJ, Gransee HM, Sieck GC, Mantilla CB. Frequency-dependent lipid raft uptake at rat diaphragm muscle axon terminals. Muscle Nerve. 2019 May; 59 (5):611-618 Epub 2019 Feb 05
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  46. Johnson RL, Abdel MP, Frank RD, Chamberlain AM, Habermann EB, Mantilla CB. Impact of Frailty on Outcomes After Primary and Revision Total Hip Arthroplasty. J Arthroplasty. 2019 Jan; 34 (1):56-64.e5 Epub 2018 Sept 25
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  47. Khurram OU, Fogarty MJ, Rana S, Vang P, Sieck GC, Mantilla CB. Diaphragm muscle function following midcervical contusion injury in rats. J Appl Physiol (1985). 2019 Jan 1; 126 (1):221-230 Epub 2018 Sept 20
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  48. Fogarty MJ, Mantilla CB, Sieck GC. Diaphragm muscle fatigue resistance does not increase with age Revista Cubana de Investigaciones Biomedicas. 2019; 38 (5):e0186
  49. Mantilla CB, Zhan WZ, Gransee HM, Prakash YS, Sieck GC. Phrenic motoneuron structural plasticity across models of diaphragm muscle paralysis. J Comp Neurol. 2018 Dec 15; 526 (18):2973-2983 Epub 2018 Nov 08
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  50. Khurram OU, Fogarty MJ, Sarrafian TL, Bhatt A, Mantilla CB, Sieck GC. Impact of aging on diaphragm muscle function in male and female Fischer 344 rats. Physiol Rep. 2018 Jul; 6 (13):e13786
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  51. Fogarty MJ, Omar TS, Zhan WZ, Mantilla CB, Sieck GC. Phrenic motor neuron loss in aged rats. J Neurophysiol. 2018 May 1; 119 (5):1852-1862 Epub 2018 Feb 07
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  52. Gonzalez Porras MA, Sieck GC, Mantilla CB. Impaired Autophagy in Motor Neurons: A Final Common Mechanism of Injury and Death. Physiology (Bethesda). 2018 May 1; 33 (3):211-224
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  53. Gonzalez Porras MA, Durfee P, Giambini S, Sieck GC, Brinker CJ, Mantilla CB. Uptake and intracellular fate of cholera toxin subunit b-modified mesoporous silica nanoparticle-supported lipid bilayers (aka protocells) in motoneurons. Nanomedicine. 2018 Apr; 14 (3):661-672 Epub 2018 Jan 12
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  54. Jimenez-Ruiz F, Khurram OU, Zhan WZ, Gransee HM, Sieck GC, Mantilla CB. Diaphragm muscle activity across respiratory motor behaviors in awake and lightly anesthetized rats. J Appl Physiol (1985). 2018 Apr 1; 124 (4):915-922 Epub 2018 Jan 04
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  55. Fogarty MJ, Mantilla CB, Sieck GC. Breathing: Motor Control of Diaphragm Muscle. Physiology (Bethesda). 2018 Mar 1; 33 (2):113-126
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  56. Khurram OU, Sieck GC, Mantilla CB. Compensatory effects following unilateral diaphragm paralysis. Respir Physiol Neurobiol. 2017 Dec; 246:39-46 Epub 2017 Aug 05
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  57. Johnson RL, Amundson AW, Abdel MP, Sviggum HP, Mabry TM, Mantilla CB, Schroeder DR, Pagnano MW, Kopp SL. Continuous Posterior Lumbar Plexus Nerve Block Versus Periarticular Injection with Ropivacaine or Liposomal Bupivacaine for Total Hip Arthroplasty: A Three-Arm Randomized Clinical Trial. J Bone Joint Surg Am. 2017 Nov 1; 99 (21):1836-1845
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  58. Mantilla CB, Gransee HM, Zhan WZ, Sieck GC. Impact of glutamatergic and serotonergic neurotransmission on diaphragm muscle activity after cervical spinal hemisection. J Neurophysiol. 2017 Sep 1; 118 (3):1732-1738 Epub 2017 June 28
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  59. Amundson AW, Johnson RL, Abdel MP, Mantilla CB, Panchamia JK, Taunton MJ, Kralovec ME, Hebl JR, Schroeder DR, Pagnano MW, Kopp SL. A Three-arm Randomized Clinical Trial Comparing Continuous Femoral Plus Single-injection Sciatic Peripheral Nerve Blocks versus Periarticular Injection with Ropivacaine or Liposomal Bupivacaine for Patients Undergoing Total Knee Arthroplasty. Anesthesiology. 2017 Jun; 126 (6):1139-1150
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  60. Gransee HM, Gonzalez Porras MA, Zhan WZ, Sieck GC, Mantilla CB. Motoneuron glutamatergic receptor expression following recovery from cervical spinal hemisection. J Comp Neurol. 2017 Apr 1; 525 (5):1192-1205 Epub 2016 Nov 03
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  61. Hernandez-Torres V, Gransee HM, Mantilla CB, Wang Y, Zhan WZ, Sieck GC. BDNF effects on functional recovery across motor behaviors after cervical spinal cord injury. J Neurophysiol. 2017 Feb 1; 117 (2):537-544 Epub 2016 Nov 09
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  62. Rana S, Sieck GC, Mantilla CB. Diaphragm electromyographic activity following unilateral midcervical contusion injury in rats. J Neurophysiol. 2017 Feb 1; 117 (2):545-555 Epub 2016 Nov 09
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  63. Mantilla CB. Gene therapy and respiratory neuroplasticity. Exp Neurol. 2017 Jan; 287: (Pt 2)261-267.
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  64. Greising SM, Vasdev AK, Zhan WZ, Sieck GC, Mantilla CB. Chronic TrkB agonist treatment in old age does not mitigate diaphragm neuromuscular dysfunction. Physiol Rep. 2017 Jan; 5 (1)
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  65. Gonzalez Porras MA, Durfee PN, Gregory AM, Sieck GC, Brinker CJ, Mantilla CB. A novel approach for targeted delivery to motoneurons using cholera toxin-B modified protocells. J Neurosci Methods. 2016 Nov 1; 273:160-174 Epub 2016 Sept 15
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  66. Abcejo AS, Sviggum HP, Mauermann ML, Hebl JR, Mantilla CB, Hanson AC, Lin Y, Jacob AK. Perioperative Nerve Injury After Peripheral Nerve Block in Patients With Previous Systemic Chemotherapy. Reg Anesth Pain Med. 2016 Nov/Dec; 41 (6):685-690
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  67. Sviggum HP, Arendt KW, Jacob AK, Niesen AD, Johnson RL, Schroeder DR, Tien M, Mantilla CB. Intrathecal Hydromorphone and Morphine for Postcesarean Delivery Analgesia: Determination of the ED90 Using a Sequential Allocation Biased-Coin Method. Anesth Analg. 2016 Sep; 123 (3):690-7
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  68. Elliott JE, Omar TS, Mantilla CB, Sieck GC. Diaphragm muscle sarcopenia in Fischer 344 and Brown Norway rats. Exp Physiol. 2016 Jul 1; 101 (7):883-94 Epub 2016 June 08
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  69. Elliott JE, Mantilla CB, Pabelick CM, Roden AC, Sieck GC. Aging-related changes in respiratory system mechanics and morphometry in mice. Am J Physiol Lung Cell Mol Physiol. 2016 Jul 1; 311 (1):L167-76 Epub 2016 June 10
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  70. Elliott JE, Greising SM, Mantilla CB, Sieck GC. Functional impact of sarcopenia in respiratory muscles. Respir Physiol Neurobiol. 2016 Jun; 226:137-46 Epub 2015 Oct 20
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  71. Gill LC, Gransee HM, Sieck GC, Mantilla CB. Functional recovery after cervical spinal cord injury: Role of neurotrophin and glutamatergic signaling in phrenic motoneurons. Respir Physiol Neurobiol. 2016 Jun; 226:128-36 Epub 2015 Oct 23
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  72. Alvarez-Argote S, Gransee HM, Mora JC, Stowe JM, Jorgenson AJ, Sieck GC, Mantilla CB. The Impact of Midcervical Contusion Injury on Diaphragm Muscle Function. J Neurotrauma. 2016 Mar 01; 33(5):500-9. Epub 2015 Nov 19.
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  73. Martinez-Galvez G, Zambrano JM, Diaz Soto JC, Zhan WZ, Gransee HM, Sieck GC, Mantilla CB. TrkB gene therapy by adeno-associated virus enhances recovery after cervical spinal cord injury. Exp Neurol. 2016 Feb; 276:31-40 Epub 2015 Dec 01
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  74. Johnson RL, Kopp SL, Burkle CM, Duncan CM, Jacob AK, Erwin PJ, Murad MH, Mantilla CB. Neuraxial vs general anaesthesia for total hip and total knee arthroplasty: a systematic review of comparative-effectiveness research. Br J Anaesth. 2016 Feb; 116 (2):163-76
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  75. Greising SM, Mantilla CB, Sieck GC. Functional Measurement of Respiratory Muscle Motor Behaviors Using Transdiaphragmatic Pressure. Methods Mol Biol. 2016; 1460:309-19
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  76. Kinney MA, Jacob AK, Passe MA, Mantilla CB. Increased Risk of Postthoracotomy Pain Syndrome in Patients with Prolonged Hospitalization and Increased Postoperative Opioid Use. Pain Res Treat. 2016; 2016:7945145 Epub 2016 June 02
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  77. Greising SM, Stowe JM, Sieck GC, Mantilla CB. Role of TrkB kinase activity in aging diaphragm neuromuscular junctions. Exp Gerontol. 2015 Dec; 72:184-91. Epub 2015 Oct 27.
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  78. Medina-Martinez JS, Greising SM, Sieck GC, Mantilla CB. Semi-automated assessment of transdiaphragmatic pressure variability across motor behaviors. Respir Physiol Neurobiol. 2015 Aug 15; 215:73-81 Epub 2015 May 21
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  79. Greising SM, Mantilla CB, Medina-Martinez JS, Stowe JM, Sieck GC. Functional impact of diaphragm muscle sarcopenia in both male and female mice. Am J Physiol Lung Cell Mol Physiol. 2015 Jul 1; 309 (1):L46-52 Epub 2015 May 01
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  80. Greising SM, Medina-Martinez JS, Vasdev AK, Sieck GC, Mantilla CB. Analysis of muscle fiber clustering in the diaphragm muscle of sarcopenic mice. Muscle Nerve. 2015 Jul; 52 (1):76-82 Epub 2015 June 01
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  81. Gill LC, Mantilla CB, Sieck GC. Impact of unilateral denervation on transdiaphragmatic pressure. Respir Physiol Neurobiol. 2015 May; 210:14-21 Epub 2015 Jan 29
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  82. Gransee HM, Zhan WZ, Sieck GC, Mantilla CB. Localized delivery of brain-derived neurotrophic factor-expressing mesenchymal stem cells enhances functional recovery following cervical spinal cord injury. J Neurotrauma. 2015 Feb 1; 32 (3):185-93 Epub 2014 Dec 10
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  83. Greising SM, Ermilov LG, Sieck GC, Mantilla CB. Ageing and neurotrophic signalling effects on diaphragm neuromuscular function. J Physiol. 2015 Jan 15; 593 (2):431-40 Epub 2014 Dec 01
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  84. Tien M, Kashyap R, Wilson GA, Hernandez-Torres V, Jacob AK, Schroeder DR, Mantilla CB. Retrospective Derivation and Validation of an Automated Electronic Search Algorithm to Identify Post Operative Cardiovascular and Thromboembolic Complications. Appl Clin Inform. 2015; 6 (3):565-76 Epub 2015 Sept 09
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  85. Seven YB, Mantilla CB, Sieck GC. Recruitment of rat diaphragm motor units across motor behaviors with different levels of diaphragm activation. J Appl Physiol (1985). 2014 Dec 1; 117 (11):1308-16 Epub 2014 Sept 25
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  86. Mantilla CB, Greising SM, Stowe JM, Zhan WZ, Sieck GC. TrkB kinase activity is critical for recovery of respiratory function after cervical spinal cord hemisection. Exp Neurol. 2014 Nov; 261:190-5 Epub 2014 June 05
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  87. Mantilla CB, Stowe JM, Sieck DC, Ermilov LG, Greising SM, Zhang C, Shokat KM, Sieck GC. TrkB kinase activity maintains synaptic function and structural integrity at adult neuromuscular junctions. J Appl Physiol (1985). 2014 Oct 15; 117 (8):910-20 Epub 2014 Aug 28
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  88. Mantilla CB, Seven YB, Sieck GC. Convergence of pattern generator outputs on a common mechanism of diaphragm motor unit recruitment. Prog Brain Res. 2014; 209:309-29
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  89. Mantilla CB, Sieck GC. Impact of diaphragm muscle fiber atrophy on neuromotor control. Respir Physiol Neurobiol. 2013 Nov 1; 189 (2):411-8 Epub 2013 July 02
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  90. Sieck GC, Mantilla CB. CrossTalk opposing view: The diaphragm muscle does not atrophy as a result of inactivity. J Physiol. 2013 Nov 1; 591(Pt 21):5259-62.
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  91. Sieck GC, Ferreira LF, Reid MB, Mantilla CB. Mechanical properties of respiratory muscles. Compr Physiol. 2013 Oct; 3 (4):1553-67
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  92. Johnson RL, Cannon EK, Mantilla CB, Cook DA. Cricoid pressure training using simulation: a systematic review and meta-analysis. Br J Anaesth. 2013 Sep; 111 (3):338-46 Epub 2013 Apr 23
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  93. Mantilla CB, Gransee HM, Zhan WZ, Sieck GC. Motoneuron BDNF/TrkB signaling enhances functional recovery after cervical spinal cord injury. Exp Neurol. 2013 Sep; 247:101-9 Epub 2013 Apr 10
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  94. Greising SM, Mantilla CB, Gorman BA, Ermilov LG, Sieck GC. Diaphragm muscle sarcopenia in aging mice. Exp Gerontol. 2013 Sep; 48 (9):881-7 Epub 2013 June 19
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  95. Memtsoudis SG, Hargett M, Russell LA, Parvizi J, Cats-Baril WL, Stundner O, Sculco TP, Consensus Conference on Bilateral Total Knee Arthroplasty Group. Consensus statement from the consensus conference on bilateral total knee arthroplasty group. Clin Orthop Relat Res. 2013 Aug; 471(8):2649-57.
  96. Greising SM, Sieck DC, Sieck GC, Mantilla CB. Novel method for transdiaphragmatic pressure measurements in mice. Respir Physiol Neurobiol. 2013 Aug 1; 188 (1):56-9 Epub 2013 Apr 28
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  97. Mantilla CB, Sieck GC. Neuromotor control in chronic obstructive pulmonary disease. J Appl Physiol (1985). 2013 May; 114(9):1246-52. Epub 2013 Jan 17.
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  98. Johnson RL, Kopp SL, Hebl JR, Erwin PJ, Mantilla CB. Falls and major orthopaedic surgery with peripheral nerve blockade: a systematic review and meta-analysis. Br J Anaesth. 2013 Apr; 110 (4):518-28 Epub 2013 Feb 24
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  99. Mantilla CB, Greising SM, Zhan WZ, Seven YB, Sieck GC. Prolonged C2 spinal hemisection-induced inactivity reduces diaphragm muscle specific force with modest, selective atrophy of type IIx and/or IIb fibers. J Appl Physiol (1985). 2013 Feb; 114 (3):380-6 Epub 2012 Nov 29
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  100. Seven YB, Mantilla CB, Zhan WZ, Sieck GC. Non-stationarity and power spectral shifts in EMG activity reflect motor unit recruitment in rat diaphragm muscle. Respir Physiol Neurobiol. 2013 Jan 15; 185 (2):400-9 Epub 2012 Sept 07
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  101. Gransee HM, Zhan WZ, Sieck GC, Mantilla CB. Targeted delivery of TrkB receptor to phrenic motoneurons enhances functional recovery of rhythmic phrenic activity after cervical spinal hemisection. PLoS One. 2013; 8 (5):e64755 Epub 2013 May 28
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  102. Brown MJ, Kor DJ, Allen MS, Kinney MO, Shen KR, Deschamps C, Nichols FC, Mauck WD, Mantilla CB. Dual-epidural catheter technique and perioperative outcomes after Ivor-Lewis esophagectomy. Reg Anesth Pain Med. 2013 Jan-Feb; 38 (1):3-8
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  103. Memtsoudis SG, Mantilla CB, Parvizi J, Stundner O, Mazumdar M. Have bilateral total knee arthroplasties become safer? A population-based trend analysis. Clin Orthop Relat Res. 2013 Jan; 471(1):17-25. Epub 2012 Sep 25.
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  104. Greising SM, Gransee HM, Mantilla CB, Sieck GC. Systems biology of skeletal muscle: fiber type as an organizing principle. Wiley Interdiscip Rev Syst Biol Med. 2012 Sep-Oct; 4 (5):457-73 Epub 2012 July 18
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  105. Sviggum HP, Jacob AK, Mantilla CB, Schroeder DR, Sperling JW, Hebl JR. Perioperative nerve injury after total shoulder arthroplasty: assessment of risk after regional anesthesia. Reg Anesth Pain Med. 2012 Sep-Oct; 37 (5):490-4
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  106. Hellyer NJ, Nokleby JJ, Thicke BM, Zhan WZ, Sieck GC, Mantilla CB. Reduced ribosomal protein s6 phosphorylation after progressive resistance exercise in growing adolescent rats. J Strength Cond Res. 2012 Jun; 26 (6):1657-66
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  107. Kinney MA, Hooten WM, Cassivi SD, Allen MS, Passe MA, Hanson AC, Schroeder DR, Mantilla CB. Chronic postthoracotomy pain and health-related quality of life. Ann Thorac Surg. 2012 Apr; 93 (4):1242-7 Epub 2012 Mar 06
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  108. Gransee HM, Mantilla CB, Sieck GC. Respiratory muscle plasticity. Compr Physiol. 2012 Apr; 2 (2):1441-62
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  109. Kinney MA, Mantilla CB, Carns PE, Passe MA, Brown MJ, Hooten WM, Curry TB, Long TR, Wass CT, Wilson PR, Weingarten TN, Huntoon MA, Rho RH, Mauck WD, Pulido JN, Allen MS, Cassivi SD, Deschamps C, Nichols FC, Shen KR, Wigle DA, Hoehn SL, Alexander SL, Hanson AC, Schroeder DR. Preoperative gabapentin for acute post-thoracotomy analgesia: a randomized, double-blinded, active placebo-controlled study. Pain Pract. 2012 Mar; 12 (3):175-83 Epub 2011 June 16
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  110. Mantilla CB, Bailey JP, Zhan WZ, Sieck GC. Phrenic motoneuron expression of serotonergic and glutamatergic receptors following upper cervical spinal cord injury. Exp Neurol. 2012 Mar; 234 (1):191-9 Epub 2011 Dec 29
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  111. Mantilla CB, Ermilov LG. The novel TrkB receptor agonist 7,8-dihydroxyflavone enhances neuromuscular transmission. Muscle Nerve. 2012 Feb; 45 (2):274-6
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  112. Sieck DC, Zhan WZ, Fang YH, Ermilov LG, Sieck GC, Mantilla CB. Structure-activity relationships in rodent diaphragm muscle fibers vs. neuromuscular junctions. Respir Physiol Neurobiol. 2012 Jan 15; 180 (1):88-96 Epub 2011 Oct 25
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  113. Dow DE, Petrilli AM, Mantilla CB, Zhan WZ, Sieck GC. Electromyogram-triggered inspiratory event detection algorithm. 6th International Conference on Soft Computing and Intelligent Systems, and 13th International Symposium on Advanced Intelligence Systems, SCIS/ISIS 2012. 2012; 789-94.
  114. Weingarten TN, Mantilla CB, Swain JM, Kendrick ML, Oberhansley JM, Burcham RJ, Ribeiro TC, Watt KD, Schroeder DR, Narr BJ, Sprung J. Nonalcoholic steatohepatitis in bariatric patients with a diagnosis of obstructive sleep apnea. Obes Facts. 2012; 5 (4):587-96 Epub 2012 Sept 05
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  115. Sieck GC, Mantilla CB. Recovery of respiratory motor function after spinal cord injury (SCI). Fudan University Journal of Medical Sciences. 2012; 39(2):111-6.
  116. Gazelka HM, Burgher AH, Huntoon MA, Mantilla CB, Hoelzer BC. Determination of the particulate size and aggregation of clonidine and corticosteroids for epidural steroid injection. Pain Physician. 2012 Jan-Feb; 15 (1):87-93
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  117. Jacob AK, Mantilla CB, Sviggum HP, Schroeder DR, Pagnano MW, Hebl JR. Perioperative nerve injury after total hip arthroplasty: regional anesthesia risk during a 20-year cohort study. Anesthesiology. 2011 Dec; 115 (6):1172-8
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  118. Mantilla CB, Sieck GC. Phrenic motor unit recruitment during ventilatory and non-ventilatory behaviors. Respir Physiol Neurobiol. 2011 Oct 15; 179 (1):57-63 Epub 2011 July 06
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  119. Pulido JN, Neal JR, Mantilla CB, Agarwal S, Lee WY, Scott PD, Hubmayr RD, Zhan WZ, Sieck GC, Farrugia G, Ereth MH, Ereth MH. Inhaled carbon monoxide attenuates myocardial inflammatory cytokine expression in a rat model of cardiopulmonary bypass. J Extra Corpor Technol. 2011 Sep; 43 (3):137-43
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  120. Mantilla CB, Seven YB, Hurtado-Palomino JN, Zhan WZ, Sieck GC. Chronic assessment of diaphragm muscle EMG activity across motor behaviors. Respir Physiol Neurobiol. 2011 Jul 31; 177 (2):176-82 Epub 2011 Mar 15
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  121. Weingarten TN, Shi Y, Mantilla CB, Hooten WM, Warner DO. Smoking and chronic pain: a real-but-puzzling relationship. Minn Med. 2011 Mar; 94(3):35-7.
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  122. Jacob AK, Mantilla CB, Sviggum HP, Schroeder DR, Pagnano MW, Hebl JR. Perioperative nerve injury after total knee arthroplasty: regional anesthesia risk during a 20-year cohort study. Anesthesiology. 2011 Feb; 114 (2):311-7
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  123. Argadine HM, Mantilla CB, Zhan WZ, Sieck GC. Intracellular signaling pathways regulating net protein balance following diaphragm muscle denervation. Am J Physiol Cell Physiol. 2011 Feb; 300 (2):C318-27 Epub 2010 Nov 17
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  124. Mantilla CB, Wass CT, Goodrich KA, Johanns CJ, Kool ML, Zhu X, Corredor JA, Warner DO, Joyner MJ, Berry DJ, Schroeder DR, Sprung J. Risk for perioperative myocardial infarction and mortality in patients undergoing hip or knee arthroplasty: the role of anemia. Transfusion. 2011 Jan; 51 (1):82-91
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  125. Hooten WM, Mantilla CB, Sandroni P, Townsend CO. Associations between heat pain perception and opioid dose among patients with chronic pain undergoing opioid tapering. Pain Med. 2010 Nov; 11 (11):1587-98 Epub 2010 Oct 01
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  126. Issa AN, Zhan WZ, Sieck GC, Mantilla CB. Neuregulin-1 at synapses on phrenic motoneurons. J Comp Neurol. 2010 Oct 15; 518 (20):4213-25
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  127. Shi Y, Weingarten TN, Mantilla CB, Hooten WM, Warner DO. Smoking and pain: pathophysiology and clinical implications. Anesthesiology. 2010 Oct; 113 (4):977-92
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  128. Hooten WM, Sandroni P, Mantilla CB, Townsend CO. Associations between heat pain perception and pain severity among patients with chronic pain. Pain Med. 2010 Oct; 11(10):1554-63. Epub 2010 Aug 30.
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  129. Mantilla CB, Seven YB, Zhan WZ, Sieck GC. Diaphragm motor unit recruitment in rats. Respir Physiol Neurobiol. 2010 Aug 31; 173 (1):101-6 Epub 2010 July 08
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  130. Prakash Y, Thompson MA, Meuchel L, Pabelick CM, Mantilla CB, Zaidi S, Martin RJ. Neurotrophins in lung health and disease. Expert Rev Respir Med. 2010 Jun; 4 (3):395-411
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  131. Ermilov LG, Pulido JN, Atchison FW, Zhan WZ, Ereth MH, Sieck GC, Mantilla CB. Impairment of diaphragm muscle force and neuromuscular transmission after normothermic cardiopulmonary bypass: effect of low-dose inhaled CO. Am J Physiol Regul Integr Comp Physiol. 2010 Mar; 298 (3):R784-9 Epub 2010 Jan 20
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  132. Mantilla CB, Sieck GC. Neuromuscular adaptations to respiratory muscle inactivity. Respir Physiol Neurobiol. 2009 Nov 30; 169 (2):133-40 Epub 2009 Sept 08
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  133. Sieck GC, Mantilla CB. Role of neurotrophins in recovery of phrenic motor function following spinal cord injury. Respir Physiol Neurobiol. 2009 Nov 30; 169 (2):218-25 Epub 2009 Aug 22
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  134. Mantilla CB, Zhan WZ, Sieck GC. Retrograde labeling of phrenic motoneurons by intrapleural injection. J Neurosci Methods. 2009 Sep 15; 182 (2):244-9 Epub 2009 June 24
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  135. Argadine HM, Hellyer NJ, Mantilla CB, Zhan WZ, Sieck GC. The effect of denervation on protein synthesis and degradation in adult rat diaphragm muscle. J Appl Physiol (1985). 2009 Aug; 107 (2):438-44 Epub 2009 June 11
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  136. Obregon G, Ermilov LG, Zhan WZ, Sieck GC, Mantilla CB. Modeling dendritic arborization based on 3D-reconstructions of adult rat phrenic motoneurons. Revista Ingenieria Biomedica. 2009 Jul-Dec; 3:47-54.
  137. Dietrich CC, Kinney MA, Pulido JN, Hoehn SL, Torsher LC, Frie ED, Hebl JR, Mantilla CB. Preoperative gabapentin in patients undergoing primary total knee arthroplasty. Acute Pain. 2009; 11(2):57-63.
  138. Dow DE, Zhan WZ, Sieck GC, Mantilla CB. Correlation of respiratory activity of contralateral diaphragm muscles for evaluation of recovery following hemiparesis. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:404-7.
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  139. Mantilla CB, Sieck GC. Trophic factor expression in phrenic motor neurons. Respir Physiol Neurobiol. 2008 Dec 10; 164 (1-2):252-62
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  140. Mantilla CB, Sieck GC. Key aspects of phrenic motoneuron and diaphragm muscle development during the perinatal period. J Appl Physiol (1985). 2008 Jun; 104 (6):1818-27 Epub 2008 Apr 10
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  141. Mantilla CB, Sill RV, Aravamudan B, Zhan WZ, Sieck GC. Developmental effects on myonuclear domain size of rat diaphragm fibers. J Appl Physiol (1985). 2008 Mar; 104(3):787-94. Epub 2008 Jan 10.
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  142. Pulido JN, Atchison FW, Zhan WZ, Ermilov LG, Neal JR, Mantilla CB, Sieck GC, Ereth MH. Normothermic cardiopulmonary bypass reduces phrenic nerve neuromuscular transmission in rats. Anesth Analg. 2008; 106 (SCA Suppl):85.
  143. Rowley KL, Mantilla CB, Ermilov LG, Sieck GC. Synaptic vesicle distribution and release at rat diaphragm neuromuscular junctions. J Neurophysiol. 2007 Jul; 98(1):478-87. Epub 2007 May 09.
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  144. Ermilov LG, Mantilla CB, Rowley KL, Sieck GC. Safety factor for neuromuscular transmission at type-identified diaphragm fibers. Muscle Nerve. 2007 Jun; 35(6):800-3.
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  145. Mantilla CB, Rowley KL, Zhan WZ, Fahim MA, Sieck GC. Synaptic vesicle pools at diaphragm neuromuscular junctions vary with motoneuron soma, not axon terminal, inactivity. Neuroscience. 2007 Apr 25; 146 (1):178-89 Epub 2007 Mar 07
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  146. Ermilov LG, Sieck GC, Zhan WZ, Mantilla CB. Neurotrophins improve synaptic transmission in the adult rodent diaphragm. Neurophysiology. 2007; 39(4-5):327-337.
  147. Geiger PC, Bailey JP, Mantilla CB, Zhan WZ, Sieck GC. Mechanisms underlying myosin heavy chain expression during development of the rat diaphragm muscle. J Appl Physiol (1985). 2006 Dec; 101(6):1546-55. Epub 2006 Jul 27.
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  148. Hellyer NJ, Mantilla CB, Park EW, Zhan WZ, Sieck GC. Neuregulin-dependent protein synthesis in C2C12 myotubes and rat diaphragm muscle. Am J Physiol Cell Physiol. 2006 Nov; 291 (5):C1056-61 Epub 2006 June 21
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  149. Prakash YS, Iyanoye A, Ay B, Mantilla CB, Pabelick CM. Neurotrophin effects on intracellular Ca2+ and force in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol. 2006 Sep; 291 (3):L447-56 Epub 2006 Apr 28
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  150. Chen BK, Miller SM, Mantilla CB, Gross L, Yaszemski MJ, Windebank AJ. Optimizing conditions and avoiding pitfalls for prolonged axonal tracing with carbocyanine dyes in fixed rat spinal cords. J Neurosci Methods. 2006 Jun 30; 154(1-2):256-63. Epub 2006 Feb 08.
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  151. Aravamudan B, Mantilla CB, Zhan WZ, Sieck GC. Denervation effects on myonuclear domain size of rat diaphragm fibers. J Appl Physiol (1985). 2006 May; 100 (5):1617-22 Epub 2006 Jan 12
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  152. Dow DE, Mantilla CB, Zhan WZ, Sieck GC. EMG-based detection of inspiration in the rat diaphragm muscle. Conf Proc IEEE Eng Med Biol Soc. 2006; 2006:1204-7
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  153. Rowley KL, Mantilla CB, Sieck GC. Respiratory muscle plasticity. Respir Physiol Neurobiol. 2005 Jul 28; 147 (2-3):235-51
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  154. Ay B, Wallace D, Mantilla CB, Prakash YS. Differential inhibition of neuronal Na+-Ca2+ exchange versus store-operated Ca2+ channels by volatile anesthetics in pheochromocytoma (PC12) cells. Anesthesiology. 2005 Jul; 103 (1):93-101
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  155. Mantilla CB, Rowley KL, Fahim MA, Zhan WZ, Sieck GC. Synaptic vesicle cycling at type-identified diaphragm neuromuscular junctions. Muscle Nerve. 2004 Dec; 30(6):774-83.
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  156. Verheul AJ, Mantilla CB, Zhan WZ, Bernal M, Dekhuijzen PN, Sieck GC. Influence of corticosteroids on myonuclear domain size in the rat diaphragm muscle. J Appl Physiol. 2004 Nov; 97(5):1715-22. Epub 2004 Jul 02.
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  157. Wong GY, Schroeder DR, Carns PE, Wilson JL, Martin DP, Kinney MO, Mantilla CB, Warner DO. Effect of neurolytic celiac plexus block on pain relief, quality of life, and survival in patients with unresectable pancreatic cancer: a randomized controlled trial. JAMA. 2004 Mar 3; 291 (9):1092-9
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  158. Mantilla CB, Zhan WZ, Sieck GC. Neurotrophins improve neuromuscular transmission in the adult rat diaphragm. Muscle Nerve. 2004 Mar; 29: (3)381-6.
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  159. Barata H, Thompson M, Zielinska W, Han YS, Mantilla CB, Prakash YS, Feitoza S, Sieck G, Chini EN. The role of cyclic-ADP-ribose-signaling pathway in oxytocin-induced Ca2+ transients in human myometrium cells. Endocrinology. 2004 Feb; 145 (2):881-9 Epub 2003 Oct 16
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  160. Zhan WZ, Mantilla CB, Sieck GC. Regulation of neuromuscular transmission by neurotrophins. Sheng Li Xue Bao. 2003 Dec 25; 55: (6)617-24.
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  161. Mantilla CB, Horlocker TT, Schroeder DR, Berry DJ, Brown DL. Risk factors for clinically relevant pulmonary embolism and deep venous thrombosis in patients undergoing primary hip or knee arthroplasty. Anesthesiology. 2003 Sep; 99 (3):552-60; discussion 5A
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  162. Geiger PC, Bailey JP, Zhan WZ, Mantilla CB, Sieck GC. Denervation-induced changes in myosin heavy chain expression in the rat diaphragm muscle. J Appl Physiol (1985). 2003 Aug; 95(2):611-9. Epub 2003 Apr 18.
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  163. Mantilla CB, Sieck GC. Invited review: Mechanisms underlying motor unit plasticity in the respiratory system. J Appl Physiol (1985). 2003 Mar; 94(3):1230-41.
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  164. Mantilla CB, Horlocker TT, Schroeder DR, Berry DJ, Brown DL. Frequency of myocardial infarction, pulmonary embolism, deep venous thrombosis, and death following primary hip or knee arthroplasty. Anesthesiology. 2002 May; 96 (5):1140-6
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  165. d'Uscio LV, Baker TA, Mantilla CB, Smith L, Weiler D, Sieck GC, Katusic ZS. Mechanism of endothelial dysfunction in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol. 2001 Jun; 21 (6):1017-22
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  166. Prakash YS, Mantilla CB, Zhan WZ, Smithson KG, Sieck GC. Phrenic motoneuron morphology during rapid diaphragm muscle growth. J Appl Physiol (1985). 2000 Aug; 89 (2):563-72
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  167. Zhan WZ, Mantilla CB, Zhan P, Bitton A, Prakash YS, de Troyer A, Sieck GC. Regional differences in serotonergic input to canine parasternal intercostal motoneurons. J Appl Physiol (1985). 2000 May; 88 (5):1581-9
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  168. Sieck GC, Mantilla CB, Prakash YS. Volume measurements in confocal microscopy. Methods Enzymol. 1999; 307:296-315
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