Faculty

Thomas G. Brott, M.D.

Publications

Chaturvedi S, Turan TN, Voeks JH, Lopes-Virella M, Goldstein J, Teal PA, Foster M, Howard V, Meschia JF, Lal B, Howard G, Brown RD Jr, Brott TG. Elevated triglycerides and treatment eligibility in patients with severe, asymptomatic carotid stenosis: CREST 2 Trials. J Stroke Cerebrovasc Dis. 2024 Dec; 33 (12):108025 Epub 2024 Oct 11
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Voeks JH, Panthofer AM, Matsumura JS, Howard VJ, Howard G, Roubin GS, Brott TG, Rosenfield K, Hanlon BM, ACT I and CREST Investigators. Sex and outcomes after stenting and endarterectomy in asymptomatic severe carotid stenosis patients. J Stroke Cerebrovasc Dis. 2024 Nov; 33 (11):108004 Epub 2024 Sept 14
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Meschia JF, Lal BK, Lazar RM, Brott TG. Unstable Plaque is a Treatable Cause of Cognitive Decline. Med Hypotheses. 2024 Sep; 190 Epub 2024 July 10
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Salem AM, Mateti NR, Adedinsewo D, Demirer M, Youssef H, Anisetti B, Shourav MMI, Middlebrooks EH, Meschia JF, Brott TG, Lin MP. Differential associations between abnormal cardiac left ventricular geometry types and cerebral white matter disease. J Stroke Cerebrovasc Dis. 2024 Jun; 33 (6):107709 Epub 2024 Apr 01
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Meschia JF, Edwards L, Roubin G, Brott TG, Lal BK. Crest-2 commitment to rigorous assessment of carotid stenting for primary prevention of stroke. Stroke-Vascular and Interventional Neurology. 2024 May; 4 (3):e001227
Erben Y, Li Y, Da Rocha-Franco JA, Tawk RG, Barrett KM, Freeman WD, Lin M, Huang JF, Miller D, Farres H, Brott TG, Meschia JF, Hakaim AG. Asymptomatic Females Are at Higher Risk for Perioperative TIA/Stroke and Males Are at Higher Risk for Long-Term Mortality after Carotid Artery Stenting: A Vascular Quality Initiative Analysis. Int J Angiol. 2024 Feb; 33 (1):36-45 Epub 2020 Sept 16
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Lal BK, Brott TG, Edwards LJ, Meschia JF. CREST-2 Reaches A Surgical Milestone. J Vasc Surg. 2023 Oct 27 [Epub ahead of print]
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Lin MP, Demirer M, Middlebrooks EH, Tawk RG, Erben YM, Mateti NR, Youssef H, Anisetti B, Elkhair AM, Gupta V, Erdal BS, Barrett KM, Brott TG, Meschia JF. Greater burden of white matter lesions and silent infarcts ipsilateral to carotid stenosis. J Stroke Cerebrovasc Dis. 2023 Sep; 32 (9):107287 Epub 2023 July 31
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Franco-Mesa C, Erben Y, Perez AF, Ball CT, Barrett KM, Pham SM, Pochettino A, Fox WC, Miller DA, Sandhu SJS, Brott TG, Meschia JF. No Sex Differences in the Prevalence of Intracranial Aneurysms in Patients with Ascending Thoracic Aortic Aneurysms: A Multi-Center Experience. Ann Vasc Surg. 2023 Jul; 93:142-148 Epub 2023 Feb 10
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Erben Y, Brott TG. Lessons from the space-2 trial in preventing carotid artery stroke in medically managed patients. Journal of Vascular Surgery. 2023 Jun; 77 (6):1575-7
Erben Y, Brott TG. Lessons from the Space-2 trial in preventing carotid artery stroke in medically managed patients. J Vasc Surg. 2023 Jun; 77 (6):1575-1577 Epub 2023 Mar 07
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Meschia JF, Lal B, Roubin G, Turan TN, Howard VJ, Benson RT, Carman K, Howard G, Brott TG. Adapting to Evolving Technologies and Treatment Guidelines in a Procedural Trial: A Qualitative Review of the CREST-2 Experience. Neurology. 2023 May 30; 100 (22):1060-1066 Epub 2023 Feb 06
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Brott TG, Meschia JF, Lal BK, Chamorro A, Howard VJ, Howard G. When Will We Have What We Need to Advise Patients How to Manage Their Carotid Stenosis?: Lessons From SPACE-2. Stroke 2023 May; 54 (5):1452-1456 Epub 2023 Mar 21
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Marshall RS, Liebeskind DS, Iii JH, Edwards LJ, Howard G, Meschia JF, Brott TG, Lal BK, Heck D, Lanzino G, Sangha N, Kashyap VS, Morales CD, Cotton-Samuel D, Rivera AM, Brickman AM, Lazar RM. Cortical Thinning in High-Grade Asymptomatic Carotid Stenosis. J Stroke. 2023 Jan; 25 (1):92-100 Epub 2023 Jan 03
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Meschia JF, Brott TG, Voeks J, Howard VJ, Howard G. Stroke Symptoms as a Surrogate in Stroke Primary Prevention Trials: The CREST Experience. Neurology. 2022 Nov 22; 99 (21):e2378-e2384 Epub 2022 Aug 26
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Meschia JF, Lal B, Brott TG. Covid-19, Contrast, and CREST-2: A Survey of Investigators. Stroke Vasc Interv Neurol. 2022 Nov; 2 (6) Epub 2022 Sept 06
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White CJ, Brott TG, Gray WA, Heck D, Jovin T, Lyden SP, Metzger DC, Rosenfield K, Roubin G, Sachar R, Siddiqui A. Carotid Artery Stenting: JACC State-of-the-Art Review. J Am Coll Cardiol. 2022 Jul 12; 80 (2):155-170
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Matsumura JS, Hanlon BM, Rosenfield K, Voeks JH, Howard G, Roubin GS, Brott TG. Treatment of carotid stenosis in asymptomatic, nonoctogenarian, standard risk patients with stenting versus endarterectomy trials. J Vasc Surg. 2022 Apr; 75 (4):1276-1283.e1 Epub 2021 Oct 22
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Meschia JF, Brott TG. Lessons From ACST-2. Stroke. 2022 Apr; 53 (4):e145-e149 Epub 2022 Mar 01
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Lal BK, Meschia JF, Jones M, Aronow HD, Lackey A, Lake R, Howard G, Brott TG. Health Screening Program to Enhance Enrollment of Women and Minorities in CREST-2. Stroke. 2022 Feb; 53 (2):355-361 Epub 2022 Jan 05
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Erben Y, Meschia JF, Heck DV, Shawl FA, Mayorga-Carlin M, Howard G, Rosenfield K, Sorkin JD, Brott TG, Lal BK. Safety of the transradial approach to carotid stenting. Catheter Cardiovasc Interv. 2022 Feb; 99 (3):814-821 Epub 2021 Aug 13
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Lazar RM, Wadley VG, Myers T, Jones MR, Heck DV, Clark WM, Marshall RS, Howard VJ, Voeks JH, Manly JJ, Moy CS, Chaturvedi S, Meschia JF, Lal BK, Brott TG, Howard G. Baseline Cognitive Impairment in Patients With Asymptomatic Carotid Stenosis in the CREST-2 Trial. Stroke. 2021 Dec; 52 (12):3855-3863 Epub 2021 Aug 26
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Haley W, Shawl F, Charles Sternbergh W 3rd, Turan TN, Barrett K, Voeks J, Brott T, Meschia JF. Non-Adherence to Antihypertensive Guidelines in Patients with Asymptomatic Carotid Stenosis. J Stroke Cerebrovasc Dis. 2021 Aug; 30 (8):105918 Epub 2021 June 18
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Fisch U, von Felten S, Wiencierz A, Jansen O, Howard G, Hendrikse J, Halliday A, Fraedrich G, Eckstein HH, Calvet D, Bulbulia R, Becquemin JP, Algra A, Rothwell P, Ringleb P, Mas JL, Brown MM, Brott TG, Bonati LH, Carotid Stenosis Trialists' Collaboration. Editor's Choice - Risk of Stroke before Revascularisation in Patients with Symptomatic Carotid Stenosis: A Pooled Analysis of Randomised Controlled Trials. Eur J Vasc Endovasc Surg. 2021 Jun; 61 (6):881-887 Epub 2021 Apr 05
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Lal BK, Meschia JF, Brott TG, Jones M, Aronow HD, Lackey A, Howard G. Race Differences in High-Grade Carotid Artery Stenosis. Stroke. 2021 Jun; 52 (6):2053-2059 Epub 2021 May 04
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Erben Y, Franco-Mesa C, Miller D, Lanzino G, Bendok BR, Li Y, Sandhu SJS, Barrett KM, Freeman WD, Lin M, Huang JF, Huynh T, Farres H, Brott TG, Hakaim AG, Brigham TJ, Todnem ND, Tawk RG, Meschia JF. Higher Risk for Reintervention in Patients after Stenting for Radiation-Induced Internal Carotid Artery Stenosis: A Single-Center Analysis and Systematic Review. Ann Vasc Surg. 2021 May; 73:1-14 Epub 2020 Dec 26
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Lin MP, Meschia JF, Gopal N, Barrett KM, Ross OA, Ertekin-Taner N, Brott TG. Cilostazol Versus Aspirin for Secondary Stroke Prevention: Systematic Review and Meta-Analysis. J Stroke Cerebrovasc Dis. 2021 Mar; 30 (3):105581 Epub 2020 Dec 31
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Howard VJ, Algra A, Howard G, Bonati LH, de Borst GJ, Bulbulia R, Calvet D, Eckstein HH, Fraedrich G, Greving JP, Halliday A, Hendrikse J, Jansen O, Brown MM, Mas JL, Ringleb PA, Brott TG, Carotid Stenosis Trialists' Collaboration. Absence of Consistent Sex Differences in Outcomes From Symptomatic Carotid Endarterectomy and Stenting Randomized Trials. Stroke. 2021 Jan; 52 (2):416-423 Epub 2021 Jan 25
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Turan TN, Meschia JF, Chimowitz MI, Roldan A, LeMatty T, Luke S, Breathitt L, Eiland R, Foley J, Brott TG. Mitigating the effects of COVID-19 pandemic on controlling vascular risk factors among participants in a carotid stenosis trial. J Stroke Cerebrovasc Dis. 2020 Dec; 29 (12):105362 Epub 2020 Sept 30
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Glover PA, Goldstein ED, Badi MK, Brigham TJ, Lesser ER, Brott TG, Meschia JF. Treatment of migraine in patients with CADASIL: A systematic review and meta-analysis. Neurol Clin Pract. 2020 Dec; 10 (6):488-496
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Erben Y, Da Rocha-Franco JA, Ball CT, Barrett KM, Freeman WD, Lin M, Tawk R, Huang JF, Vibhute P, Oderich G, Miller DA, Farres H, Davila V, Money SR, Meltzer AJ, Hakaim AG, Brott TG, Meschia JF. Prevalence of Intracranial Aneurysms in Patients with Infrarenal Abdominal Aortic Aneurysms: A Multicenter Experience. Int J Angiol. 2020 Dec; 29 (4):229-236 Epub 2020 June 27
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Gendron TF, Badi MK, Heckman MG, Jansen-West KR, Vilanilam GK, Johnson PW, Burch AR, Walton RL, Ross OA, Brott TG, Miller TM, Berry JD, Nicholson KA, Wszolek ZK, Oskarsson BE, Sheth KN, Sansing LH, Falcone GJ, Cucchiara BL, Meschia JF, Petrucelli L. Plasma neurofilament light predicts mortality in patients with stroke. Sci Transl Med. 2020 Nov 11; 12 (569)
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Turan TN, Voeks JH, Chimowitz MI, Roldan A, LeMatty T, Haley W, Lopes-Virella M, Chaturvedi S, Jones M, Heck D, Howard G, Lal BK, Meschia JF, Brott TG. Rationale, Design, and Implementation of Intensive Risk Factor Treatment in the CREST2 Trial. Stroke. 2020 Oct; 51 (10):2960-2971 Epub 2020 Sept 21
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Meschia JF, Barrett KM, Brown RD Jr, Turan TN, Howard VJ, Voeks JH, Lal BK, Howard G, Brott TG. The CREST-2 experience with the evolving challenges of COVID-19: A clinical trial in a pandemic. Neurology. 2020 Jul 7; 95 (1):29-36 Epub 2020 May 01
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Erben Y, Li Y, Da Rocha-Franco JA, Tawk RG, Barrett KM, Freeman WD, Lin M, Miller D, Beck AW, Scali ST, Farres H, Brott TG, Meschia JF, Hakaim AG. Higher Long-Term Mortality with Carotid Artery Stenting in Asymptomatic Male Compared with Female Patients in the Southeastern Vascular Study Group. Ann Vasc Surg. 2020 Jul; 66:390-399 Epub 2020 Feb 03
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Erben Y, Barrett KM, Freeman WD, Lin M, Tawk R, Ball CT, Melton VS, Thuro LM, Hakaim AG, Brott TG, Meschia JF. Prevalence of Previously Undiagnosed Abdominal Aortic Aneurysms in Patients with Intracranial Aneurysms: From the Brain and Aortic Aneurysms Study (BAAS). Neurocrit Care. 2020 Jun; 32 (3):796-803
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Poorthuis MHF, Bulbulia R, Morris DR, Pan H, Rothwell PM, Algra A, Becquemin JP, Bonati LH, Brott TG, Brown MM, Calvet D, Eckstein HH, Fraedrich G, Gregson J, Greving JP, Hendrikse J, Howard G, Jansen O, Mas JL, Lewis SC, de Borst GJ, Halliday A, Carotid Stenosis Trialists' Collaboration. Timing of procedural stroke and death in asymptomatic patients undergoing carotid endarterectomy: individual patient analysis from four RCTs. Br J Surg. 2020 May; 107 (6):662-668 Epub 2020 Mar 12
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Lin MP, Brott TG, Liebeskind DS, Meschia JF, Sam K, Gottesman RF. Collateral Recruitment Is Impaired by Cerebral Small Vessel Disease. Stroke. 2020 May; 51 (5):1404-1410 Epub 2020 Apr 06
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Lal BK, Meschia JF, Roubin GS, Jankowitz B, Heck D, Jovin T, White CJ, Rosenfield K, Katzen B, Dabus G, Gray W, Matsumura J, Hopkins LN, Luke S, Sharma J, Voeks JH, Howard G, Brott TG, CREST-2 Investigators. Factors influencing credentialing of interventionists in the CREST-2 trial. J Vasc Surg. 2020 Mar; 71 (3):854-861 Epub 2019 July 26
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Porter AL, Ebot J, Lane K, Mooney LH, Lannen AM, Richie EM, Dlugash R, Mayo S, Brott TG, Ziai W, Freeman WD, Hanley DF. Enhancing the Informed Consent Process Using Shared Decision Making and Consent Refusal Data from the CLEAR III Trial. Neurocrit Care. 2020 Feb; 32 (1):340-347
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Lal BK, Roubin GS, Rosenfield K, Heck D, Jones M, Jankowitz B, Jovin T, Chaturvedi S, Dabus G, White CJ, Gray W, Matsumura J, Katzen BT, Hopkins LN, Mayorga-Carlin M, Sorkin JD, Howard G, Meschia JF, Brott TG. Quality Assurance for Carotid Stenting in the CREST-2 Registry. J Am Coll Cardiol. 2019 Dec 24; 74 (25):3071-3079
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Knappich C, Kuehnl A, Haller B, Salvermoser M, Algra A, Becquemin JP, Bonati LH, Bulbulia R, Calvet D, Fraedrich G, Gregson J, Halliday A, Hendrikse J, Howard G, Jansen O, Malas MB, Ringleb PA, Brown MM, Mas JL, Brott TG, Morris DR, Lewis SC, Eckstein HH. Associations of Perioperative Variables With the 30-Day Risk of Stroke or Death in Carotid Endarterectomy for Symptomatic Carotid Stenosis. Stroke. 2019 Dec; 50 (12):3439-3448 Epub 2019 Nov 18
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Badi MK, Vilanilam GK, Gupta V, Barrett KM, Lesser ER, Cochuyt JJ, Hodge DO, Brott TG, Meschia JF. Pharmacotherapy for Patients with Atrial Fibrillation and Cerebral Microbleeds. J Stroke Cerebrovasc Dis. 2019 Aug; 28 (8):2159-2167 Epub 2019 May 15
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Muller MD, von Felten S, Algra A, Becquemin JP, Bulbulia R, Calvet D, Eckstein HH, Fraedrich G, Halliday A, Hendrikse J, Howard G, Gregson J, Jansen O, Brown MM, Mas JL, Brott TG, Ringleb PA, Bonati LH. Secular Trends in Procedural Stroke or Death Risks of Stenting Versus Endarterectomy for Symptomatic Carotid Stenosis. Circ Cardiovasc Interv. 2019 Aug; 12 (8):e007870 Epub 2019 Aug 05
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Moore WS, Voeks JH, Roubin GS, Clark WM, Howard VJ, Jones MR, Brott TG, CREST Investigators. Duration of asymptomatic status and outcomes following carotid endarterectomy and carotid artery stenting in the Carotid Revascularization Endarterectomy vs Stenting Trial. J Vasc Surg. 2019 Jun; 69 (6):1797-1800 Epub 2019 Jan 08
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Hasan D, Zanaty M, Starke RM, Atallah E, Chalouhi N, Jabbour P, Singla A, Guerrero WR, Nakagawa D, Samaniego EA, Mbabuike N, Tawk RG, Siddiqui AH, Levy EI, Novakovic RL, White J, Schirmer CM, Brott TG, Shallwani H, Hopkins LN. Feasibility, safety, and changes in systolic blood pressure associated with endovascular revascularization of symptomatic and chronically occluded cervical internal carotid artery using a newly suggested radiographic classification of chronically occluded cervical internal carotid artery: pilot study. J Neurosurg. 2019 May 1; 130 (5):1468-1477 Epub 2018 May 18
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Huang P, Freeman WD, Edenfield BH, Brott TG, Meschia JF, Zubair AC. Safety and Efficacy of Intraventricular Delivery of Bone Marrow-Derived Mesenchymal Stem Cells in Hemorrhagic Stroke Model. Sci Rep. 2019 Apr 5; 9 (1):5674 Epub 2019 Apr 05
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Brott TG, Calvet D, Howard G, Gregson J, Algra A, Becquemin JP, de Borst GJ, Bulbulia R, Eckstein HH, Fraedrich G, Greving JP, Halliday A, Hendrikse J, Jansen O, Voeks JH, Ringleb PA, Mas JL, Brown MM, Bonati LH, Carotid Stenosis Trialists' Collaboration. Long-term outcomes of stenting and endarterectomy for symptomatic carotid stenosis: a preplanned pooled analysis of individual patient data. Lancet Neurol. 2019 Apr; 18 (4):348-356 Epub 2019 Feb 06
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Hasan TF, Barrett KM, Brott TG, Badi MK, Lesser ER, Hodge DO, Meschia JF. Severity of white matter hyperintensities and effects on all-cause mortality in the Mayo Clinic Florida Familial Cerebrovascular Diseases Registry Mayo Clinic Proceedings. 2019; 94(3):380-2.
Hasan TF, Barrett KM, Brott TG, Badi MK, Lesser ER, Hodge DO, Meschia JF. Severity of White Matter Hyperintensities and Effects on All-Cause Mortality in the Mayo Clinic Florida Familial Cerebrovascular Diseases Registry. Mayo Clin Proc. 2019 Mar; 94 (3):408-416
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Lal BK, Roubin GS, Jones M, Clark W, Mackey A, Hill MD, Voeks JH, Howard G, Hobson RW 2nd, Brott TG. Influence of multiple stents on periprocedural stroke after carotid artery stenting in the Carotid Revascularization Endarterectomy versus Stent Trial (CREST). J Vasc Surg. 2019 Mar; 69 (3):800-806 Epub 2018 Dec 04
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Volkers EJ, Algra A, Kappelle LJ, Becquemin JP, de Borst GJ, Brown MM, Bulbulia R, Calvet D, Eckstein HH, Fraedrich G, Gregson J, Halliday A, Hendrikse J, Howard G, Jansen O, Roubin GS, Bonati LH, Brott TG, Mas JL, Ringleb PA, Greving JP, Carotid Stenosis Trialists' Collaboration. Safety of Carotid Revascularization in Patients With a History of Coronary Heart Disease. Stroke. 2019 Feb; 50 (2):413-418
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Norling AM, Marshall RS, Pavol MA, Howard G, Howard V, Liebeskind D, Huston J 3rd, Lal BK, Brott TG, Lazar RM. Is Hemispheric Hypoperfusion a Treatable Cause of Cognitive Impairment? Curr Cardiol Rep. 2019 Jan 19; 21 (1):4
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Marshall RS, Lazar RM, Liebeskind DS, Connolly ES, Howard G, Lal BK, Huston J 3rd, Meschia JF, Brott TG. Carotid revascularization and medical management for asymptomatic carotid stenosis - Hemodynamics (CREST-H): Study design and rationale. Int J Stroke. 2018 Dec; 13 (9):985-991 Epub 2018 Aug 22
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Muller MD, von Felten S, Algra A, Becquemin JP, Brown M, Bulbulia R, Calvet D, Eckstein HH, Fraedrich G, Halliday A, Hendrikse J, Gregson J, Howard G, Jansen O, Mas JL, Brott TG, Ringleb PA, Bonati LH, Carotid Stenosis Trialists' Collaboration. Immediate and Delayed Procedural Stroke or Death in Stenting Versus Endarterectomy for Symptomatic Carotid Stenosis. Stroke. 2018 Nov; 49 (11):2715-2722
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Jones MR, Howard G, Roubin GS, Blackshear JL, Cohen DJ, Cutlip DE, Leimgruber PP, Rhodes D, Prineas RJ, Glasser SP, Lal BK, Voeks JH, Brott TG, CREST Investigators. Periprocedural Stroke and Myocardial Infarction as Risks for Long-Term Mortality in CREST. Circ Cardiovasc Qual Outcomes. 2018 Nov; 11 (11):e004663
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Leifheit EC, Wang Y, Howard G, Howard VJ, Goldstein LB, Brott TG, Lichtman JH. Outcomes after carotid endarterectomy among elderly dual Medicare-Medicaid-eligible patients. Neurology. 2018 Oct 23; 91 (17):e1553-e1558 Epub 2018 Sept 28
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Volkers EJ, Algra A, Kappelle LJ, Jansen O, Howard G, Hendrikse J, Halliday A, Gregson J, Fraedrich G, Eckstein HH, Calvet D, Bulbulia R, Brown MM, Becquemin JP, Ringleb PA, Mas JL, Bonati LH, Brott TG, Greving JP, Carotid Stenosis Trialists' Collaboration. Prediction Models for Clinical Outcome After a Carotid Revascularization Procedure. Stroke. 2018 Aug; 49 (8):1880-1885
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Balucani C, Arnedo V, Weedon J, Leys D, Mas JL, Brown M, Grotta JC, Gonzales NR, Hacke W, Brott T, Levine SR. Transatlantic Differences in Management of Carotid Stenosis: BRIDGing the Gap in StrokE Management (BRIDGE) Project. Neurohospitalist. 2018 Jul; 8 (3):113-123 Epub 2018 Jan 17
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Jones DW, Brott TG, Schermerhorn ML. Trials and Frontiers in Carotid Endarterectomy and Stenting. Stroke. 2018 Jul; 49 (7):1776-1783 Epub 2018 June 04
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Hacke W, Lyden P, Emberson J, Baigent C, Blackwell L, Albers G, Bluhmki E, Brott T, Cohen G, Davis SM, Donnan GA, Grotta JC, Howard G, Kaste M, Koga M, von Kummer R, Lansberg MG, Lindley RI, Olivot JM, Parsons M, Sandercock PA, Toni D, Toyoda K, Wahlgren N, Wardlaw JM, Whiteley WN, Del Zoppo G, Lees KR, Stroke Thrombolysis Trialists' Collaborators Group. Effects of alteplase for acute stroke according to criteria defining the European Union and United States marketing authorizations: Individual-patient-data meta-analysis of randomized trials. Int J Stroke. 2018 Feb; 13 (2):175-189 Epub 2017 Nov 24
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Meschia JF, Brott T. Ischaemic stroke. Eur J Neurol. 2018 Jan; 25 (1):35-40 Epub 2017 Sept 21
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Sheffet AJ, Howard G, Sam A, Jamil Z, Weaver F, Chiu D, Voeks JH, Howard VJ, Hughes SE, Flaxman L, Longbottom ME, Brott TG, CREST Investigators. Challenge and Yield of Enrolling Racially and Ethnically Diverse Patient Populations in Low Event Rate Clinical Trials. Stroke. 2018 Jan; 49 (1):84-89 Epub 2017 Nov 30
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Howard VJ, Meschia JF, Lal BK, Turan TN, Roubin GS, Brown RD Jr, Voeks JH, Barrett KM, Demaerschalk BM, Huston J 3rd, Lazar RM, Moore WS, Wadley VG, Chaturvedi S, Moy CS, Chimowitz M, Howard G, Brott TG, CREST-2 study investigators. Carotid revascularization and medical management for asymptomatic carotid stenosis: Protocol of the CREST-2 clinical trials. Int J Stroke. 2017 Oct; 12 (7):770-778 Epub 2017 May 02
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Lichtman JH, Jones MR, Leifheit EC, Sheffet AJ, Howard G, Lal BK, Howard VJ, Wang Y, Curtis J, Brott TG. Carotid Endarterectomy and Carotid Artery Stenting in the US Medicare Population, 1999-2014. JAMA. 2017 Sep 19; 318 (11):1035-1046
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Lal BK, Meschia JF, Howard G, Brott TG. Carotid Stenting Versus Carotid Endarterectomy: What Did the Carotid Revascularization Endarterectomy Versus Stenting Trial Show and Where Do We Go From Here? Angiology. 2017 Sep; 68 (8):675-682 Epub 2016 Aug 09
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Demaerschalk BM, Brown RD Jr, Roubin GS, Howard VJ, Cesko E, Barrett KM, Longbottom ME, Voeks JH, Chaturvedi S, Brott TG, Lal BK, Meschia JF, Howard G, CREST-2 Investigators. Factors Associated With Time to Site Activation, Randomization, and Enrollment Performance in a Stroke Prevention Trial. Stroke. 2017 Sep; 48 (9):2511-2518 Epub 2017 Aug 02
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Grotta JC, Lyden P, Brott T. Rethinking Training and Distribution of Vascular Neurology Interventionists in the Era of Thrombectomy. Stroke. 2017 Aug; 48 (8):2313-2317 Epub 2017 July 13
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Meschia JF, Klaas JP, Brown RD Jr, Brott TG. Evaluation and Management of Atherosclerotic Carotid Stenosis. Mayo Clin Proc. 2017 Jul; 92 (7):1144-1157
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Rantner B, Kollerits B, Roubin GS, Ringleb PA, Jansen O, Howard G, Hendrikse J, Halliday A, Gregson J, Eckstein HH, Calvet D, Bulbulia R, Bonati LH, Becquemin JP, Algra A, Brown MM, Mas JL, Brott TG, Fraedrich G, Carotid Stenosis Trialists' Collaboration. Early Endarterectomy Carries a Lower Procedural Risk Than Early Stenting in Patients With Symptomatic Stenosis of the Internal Carotid Artery: Results From 4 Randomized Controlled Trials. Stroke. 2017 Jun; 48 (6):1580-1587 Epub 2017 Apr 28
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Volkers EJ, Greving JP, Hendrikse J, Algra A, Kappelle LJ, Becquemin JP, Bonati LH, Brott TG, Bulbulia R, Calvet D, Eckstein HH, Fraedrich G, Gregson J, Halliday A, Howard G, Jansen O, Roubin GS, Brown MM, Mas JL, Ringleb PA, Carotid Stenosis Trialists' Collaboration. Body mass index and outcome after revascularization for symptomatic carotid artery stenosis. Neurology. 2017 May 23; 88 (21):2052-2060 Epub 2017 Apr 26
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Heck DV, Roubin GS, Rosenfield KG, Gray WA, White CJ, Jovin TG, Matsumura JS, Lal BK, Katzen BT, Dabus G, Jankowitz BT, Brott TG. Asymptomatic carotid stenosis: Medicine alone or combined with carotid revascularization. Neurology. 2017 May 23; 88 (21):2061-2065 Epub 2017 Apr 26
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Lal BK, Meschia JF, Brott TG. Clinical need, design, and goals for the Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis trial. Semin Vasc Surg. 2017 Mar; 30 (1):2-7 Epub 2017 Apr 27
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Barrett KM, Brott TG. Stroke Caused by Extracranial Disease. Circ Res. 2017 Feb 03; 120: (3)496-501.
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Whiteley WN, Emberson J, Lees KR, Blackwell L, Albers G, Bluhmki E, Brott T, Cohen G, Davis S, Davis S, Donnan G, Grotta J, Howard G, Kaste M, Koga M, von Kummer R, Lansberg MG, Lindley RI, Lyden P, Olivot JM, Parsons M, Toni D, Toyoda K, Wahlgren N, Wardlaw J, Del Zoppo GJ, Sandercock P, Hacke W, Baigent C, Stroke Thrombolysis Trialists' Collaboration. Risk of intracerebral haemorrhage with alteplase after acute ischaemic stroke: a secondary analysis of an individual patient data meta-analysis. Lancet Neurol. 2016 Aug; 15 (9):925-933 Epub 2016 June 08
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Hye RJ, Voeks JH, Malas MB, Tom M, Longson S, Blackshear JL, Brott TG. Anesthetic type and risk of myocardial infarction after carotid endarterectomy in the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST). J Vasc Surg. 2016 Jul; 64 (1):3-8.e1 Epub 2016 Mar 16
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Jalbert JJ, Nguyen LL, Gerhard-Herman MD, Kumamaru H, Chen CY, Williams LA, Liu J, Rothman AT, Jaff MR, Seeger JD, Benenati JF, Schneider PA, Aronow HD, Johnston JA, Brott TG, Tsai TT, White CJ, Setoguchi S. Comparative Effectiveness of Carotid Artery Stenting Versus Carotid Endarterectomy Among Medicare Beneficiaries. Circ Cardiovasc Qual Outcomes. 2016 May; 9 (3):275-85 Epub 2016 Apr 26
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Yamazaki Y, Baker DJ, Tachibana M, Liu CC, van Deursen JM, Brott TG, Bu G, Kanekiyo T. Vascular Cell Senescence Contributes to Blood-Brain Barrier Breakdown. Stroke. 2016 Apr; 47 (4):1068-77 Epub 2016 Feb 16
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Moore WS, Popma JJ, Roubin GS, Voeks JH, Cutlip DE, Jones M, Howard G, Brott TG, CREST Investigators. Carotid angiographic characteristics in the CREST trial were major contributors to periprocedural stroke and death differences between carotid artery stenting and carotid endarterectomy. J Vasc Surg. 2016 Apr; 63 (4):851-7, 858.e1 Epub 2015 Nov 21
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Howard G, Roubin GS, Jansen O, Hendrikse J, Halliday A, Fraedrich G, Eckstein HH, Calvet D, Bulbulia R, Bonati LH, Becquemin JP, Algra A, Brown MM, Ringleb PA, Brott TG, Mas JL, Carotid Stenting Trialists' Collaboration. Association between age and risk of stroke or death from carotid endarterectomy and carotid stenting: a meta-analysis of pooled patient data from four randomised trials. Lancet. 2016 Mar 26; 387 (10025):1305-11 Epub 2016 Feb 12
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Brott TG, Howard G, Roubin GS, Meschia JF, Mackey A, Brooks W, Moore WS, Hill MD, Mantese VA, Clark WM, Timaran CH, Heck D, Leimgruber PP, Sheffet AJ, Howard VJ, Chaturvedi S, Lal BK, Voeks JH, Hobson RW 2nd, CREST Investigators. Long-Term Results of Stenting versus Endarterectomy for Carotid-Artery Stenosis. N Engl J Med. 2016 Mar 17; 374 (11):1021-31 Epub 2016 Feb 18
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Brott TG, Voeks JH, Howard VJ. Dr. Brott and colleagues reply New England Journal of Medicine. 2016; 375: (6)604.
Meschia JF, Hopkins LN, Altafullah I, Wechsler LR, Stotts G, Gonzales NR, Voeks JH, Howard G, Brott TG. Time From Symptoms to Carotid Endarterectomy or Stenting and Perioperative Risk. Stroke. 2015 Dec; 46 (12):3540-2 Epub 2015 Oct 22
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Sheffet AJ, Voeks JH, Mackey A, Brooks W, Clark WM, Hill MD, Howard VJ, Hughes SE, Tom M, Longbottom ME, Brott TG, CREST Investigators. Characteristics of participants consenting versus declining follow-up for up to 10 years in a randomized clinical trial. Clin Trials. 2015 Dec; 12 (6):657-63 Epub 2015 June 29
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Jalbert JJ, Gerhard-Herman MD, Nguyen LL, Jaff MR, Kumamaru H, Williams LA, Chen CY, Liu J, Seeger JD, Rothman AT, Schneider P, Brott TG, Tsai TT, Aronow HD, Johnston JA, Setoguchi S. Relationship Between Physician and Hospital Procedure Volume and Mortality After Carotid Artery Stenting Among Medicare Beneficiaries. Circ Cardiovasc Qual Outcomes. 2015 Oct; 8 (6 Suppl 3):S81-9
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Voeks JH, Howard G, Roubin G, Farb R, Heck D, Logan W, Longbottom M, Sheffet A, Meschia JF, Brott TG. Mediators of the Age Effect in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST). Stroke. 2015 Oct; 46 (10):2868-73 Epub 2015 Sept 08
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Howard G, Hopkins LN, Moore WS, Katzen BT, Chakhtoura E, Morrish WF, Ferguson RD, Hye RJ, Shawl FA, Harrigan MR, Voeks JH, Howard VJ, Lal BK, Meschia JF, Brott TG. Temporal Changes in Periprocedural Events in the Carotid Revascularization Endarterectomy Versus Stenting Trial. Stroke. 2015 Aug; 46 (8):2183-9 Epub 2015 July 14
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Liebeskind DS, Albers GW, Crawford K, Derdeyn CP, George MS, Palesch YY, Toga AW, Warach S, Zhao W, Brott TG, Sacco RL, Khatri P, Saver JL, Cramer SC, Wolf SL, Broderick JP, Wintermark M. Imaging in StrokeNet: Realizing the Potential of Big Data. Stroke. 2015 Jul; 46 (7):2000-6 Epub 2015 June 04
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Hye RJ, Mackey A, Hill MD, Voeks JH, Cohen DJ, Wang K, Tom M, Brott TG. Incidence, outcomes, and effect on quality of life of cranial nerve injury in the Carotid Revascularization Endarterectomy versus Stenting Trial. J Vasc Surg. 2015 May; 61 (5):1208-14 Epub 2015 Mar 12
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Jalbert JJ, Nguyen LL, Gerhard-Herman MD, Jaff MR, White CJ, Rothman AT, Seeger JD, Kumamaru H, Williams LA, Chen CY, Liu J, Tsai TT, Aronow HD, Johnston JA, Brott TG, Setoguchi S. Outcomes after carotid artery stenting in Medicare beneficiaries, 2005 to 2009. JAMA Neurol. 2015 Mar; 72 (3):276-86
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Malas M, Glebova NO, Hughes SE, Voeks JH, Qazi U, Moore WS, Lal BK, Howard G, Llinas R, Brott TG. Effect of patching on reducing restenosis in the carotid revascularization endarterectomy versus stenting trial. Stroke. 2015 Mar; 46 (3):757-61 Epub 2015 Jan 22
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Emberson J, Lees KR, Lyden P, Blackwell L, Albers G, Bluhmki E, Brott T, Cohen G, Davis S, Donnan G, Grotta J, Howard G, Kaste M, Koga M, von Kummer R, Lansberg M, Lindley RI, Murray G, Olivot JM, Parsons M, Tilley B, Toni D, Toyoda K, Wahlgren N, Wardlaw J, Whiteley W, del Zoppo GJ, Baigent C, Sandercock P, Hacke W, Stroke Thrombolysis Trialists' Collaborative Group. Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials. Lancet. 2014 Nov 29; 384 (9958):1929-35 Epub 2014 Aug 05
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Meschia JF, Voeks JH, Leimgruber PP, Mantese VA, Timaran CH, Chiu D, Demaerschalk BM, Howard VJ, Hughes SE, Longbottom M, Howard AG, Brott TG. Management of vascular risk factors in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST). J Am Heart Assoc. 2014 Nov 26; 3 (6):e001180
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Gonzales NR, Demaerschalk BM, Voeks JH, Tom M, Howard G, Sheffet AJ, Garcia L, Clair DG, Barr J, Orlow S, Brott TG, CREST Investigators. Complication rates and center enrollment volume in the carotid revascularization endarterectomy versus stenting trial. Stroke. 2014 Nov; 45 (11):3320-4 Epub 2014 Sept 25
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Howard G, Voeks JH, Meschia JF, Howard VJ, Brott TG. Picking the good apples: statistics versus good judgment in choosing stent operators for a multicenter clinical trial. Stroke. 2014 Nov; 45 (11):3325-9 Epub 2014 Sept 11
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Rodes-Cabau J, Kahlert P, Neumann FJ, Schymik G, Webb JG, Amarenco P, Brott T, Garami Z, Gerosa G, Lefevre T, Plicht B, Pocock SJ, Schlamann M, Thomas M, Diamond B, Merioua I, Beyersdorf F, Vahanian A. Feasibility and exploratory efficacy evaluation of the Embrella Embolic Deflector system for the prevention of cerebral emboli in patients undergoing transcatheter aortic valve replacement: the PROTAVI-C pilot study. JACC Cardiovasc Interv. 2014 Oct; 7 (10):1146-55
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Huang P, Gebhart N, Richelson E, Brott TG, Meschia JF, Zubair AC. Mechanism of mesenchymal stem cell-induced neuron recovery and anti-inflammation. Cytotherapy. 2014 Oct; 16 (10):1336-44 Epub 2014 June 11
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Kumamaru H, Judd SE, Curtis JR, Ramachandran R, Hardy NC, Rhodes JD, Safford MM, Kissela BM, Howard G, Jalbert JJ, Brott TG, Setoguchi S. Validity of claims-based stroke algorithms in contemporary Medicare data: reasons for geographic and racial differences in stroke (REGARDS) study linked with medicare claims. Circ Cardiovasc Qual Outcomes. 2014 Jul; 7 (4):611-9 Epub 2014 June 24
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Zaidat OO, Castonguay AC, Nguyen TN, Becker KJ, Derdeyn CP, Nelson PK, Amarenco P, Brott TG. Impact of SAMMPRIS on the future of intracranial atherosclerotic disease management: polling results from the ICAD symposium at the International Stroke Conference. J Neurointerv Surg. 2014 Apr 1; 6(3):225-30. Epub 2013 Apr 06.
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Rubin MN, Barrett KM, Brott TG, Meschia JF. Asymptomatic carotid stenosis: What we can learn from the next generation of randomized clinical trials. JRSM Cardiovasc Dis. 2014 Jan; 3:2048004014529419 Epub 2014 Apr 08
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Sheffet AJ, Flaxman L, Tom M, Hughes SE, Longbottom ME, Howard VJ, Marler JR, Brott TG. Financial management of a large multisite randomized clinical trial. International Journal of Stroke. 2014; 9(6):811-3.
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Zierler RE, Beach KW, Bergelin RO, Lal BK, Moore WS, Roubin GS, Voeks JH, Brott TG, CREST Investigators. Agreement between site-reported and ultrasound core laboratory results for duplex ultrasound velocity measurements in the Carotid Revascularization Endarterectomy versus Stenting Trial. J Vasc Surg. 2014 Jan; 59 (1):2-7 Epub 2013 Sept 19
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Vickrey BG, Brott TG, Koroshetz WJ, Stroke Research Priorities Meeting Steering Committee and the National Advisory Neurological Disorders and Stroke Council, National Institute of Neurological Disorders and Stroke. Research priority setting: a summary of the 2012 NINDS Stroke Planning Meeting Report. Stroke. 2013 Aug; 44(8):2338-42. Epub 2013 Jul 02.
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Kennedy RE, Adragni KP, Tiwari HK, Voeks JH, Brott TG, Howard G. Risk-stratified imputation in survival analysis. Clin Trials. 2013 Aug; 10(4):530-9. Epub 2013 Jul 01.
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Meschia JF, Barrett KM, Brott TG. Reperfusion therapy for acute ischemic stroke: how should we react to the Third Interventional Management of Stroke (IMS III) trial? Mayo Clin Proc. 2013 Jul; 88(7):653-7. Epub 2013 May 29.
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Johnston KC, Brott TG. Stroke Progress Review Group: looking back and going forward: introduction. Stroke. 2013 Jun; 44(6 Suppl 1):S110.
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Blackshear JL, Brott TG. Ascertainment of any and all neurologic and myocardial damage in carotid revascularization: the key to optimization? Expert Rev Cardiovasc Ther. 2013 Apr; 11(4):469-84.
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Barrett KM, Ossi RG, Brott TG, Meschia JF. Clinical, anatomic, and procedural durability of carotid revascularization. J Stroke Cerebrovasc Dis. 2013 Apr; 22(3):218-26. Epub 2011 Sep 13.
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Anderson CD, Biffi A, Nalls MA, Devan WJ, Schwab K, Ayres AM, Valant V, Ross OA, Rost NS, Saxena R, Viswanathan A, Worrall BB, Brott TG, Goldstein JN, Brown D, Broderick JP, Norrving B, Greenberg SM, Silliman SL, Hansen BM, Tirschwell DL, Lindgren A, Slowik A, Schmidt R, Selim M, Roquer J, Montaner J, Singleton AB, Kidwell CS, Woo D, Furie KL, Meschia JF, Rosand J, International Stroke Genetics Consortium. Common variants within oxidative phosphorylation genes influence risk of ischemic stroke and intracerebral hemorrhage. Stroke. 2013 Mar; 44(3):612-9. Epub 2013 Jan 29.
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Heckman MG, Soto-Ortolaza AI, Diehl NN, Rayaprolu S, Brott TG, Wszolek ZK, Meschia JF, Ross OA. Genetic variants associated with myocardial infarction in the PSMA6 gene and Chr9p21 are also associated with ischaemic stroke. Eur J Neurol. 2013 Feb; 20 (2):300-8 Epub 2012 Aug 06
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Timaran CH, Mantese VA, Malas M, Brown OW, Lal BK, Moore WS, Voeks JH, Brott TG, CREST Investigators. Differential outcomes of carotid stenting and endarterectomy performed exclusively by vascular surgeons in the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST). J Vasc Surg. 2013 Feb; 57(2):303-8. Epub 2012 Dec 20.
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Brott TG, Halperin JL, Abbara S, Bacharach JM, Barr JD, Bush RL, Cates CU, Creager MA, Fowler SB, Friday G, Hertzberg VS, McIff EB, Moore WS, Panagos PD, Riles TS, Rosenwasser RH, Taylor AJ, Jacobs AK, Smith SC Jr, Anderson JL, Adams CD, Albert N, Buller CE, Creager MA, Ettinger SM, Guyton RA, Halperin JL, Hochman JS, Hunt SA, Krumholz HM, Kushner FG, Lytle BW, Nishimura RA, Ohman EM, Page RL, Riegel B, Stevenson WG, Tarkington LG, Yancy CW. 2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS guideline on the management of patients with extracranial carotid and vertebral artery disease: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American Stroke Association, American Association of Neuroscience Nurses, American Association of Neurological Surgeons, American College of Radiology, American Society of Neuroradiology, Congress of Neurological Surgeons, Society of Atherosclerosis Imaging and Prevention, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of NeuroInterventional Surgery, Society for Vascular Medicine, and Society for Vascular Surgery. Developed in collaboration with the American Academy of Neurology and Society of Cardiovascular Computed Tomography. Catheter Cardiovasc Interv. 2013 Jan 01; 81(1):E76-123. Epub 2011 Feb 03.
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Ross OA, Soto-Ortolaza AI, Heckman MG, Verbeeck C, Serie DJ, Rayaprolu S, Rich SS, Nalls MA, Singleton A, Guerreiro R, Kinsella E, Wszolek ZK, Brott TG, Brown RD Jr, Worrall BB, Meschia JF. NOTCH3 variants and risk of ischemic stroke. PLoS One. 2013; 8 (9):e75035 Epub 2013 Sept 23
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Hill MD, Brooks W, Mackey A, Clark WM, Meschia JF, Morrish WF, Mohr JP, Rhodes JD, Popma JJ, Lal BK, Longbottom ME, Voeks JH, Howard G, Brott TG, CREST Investigators. Stroke after carotid stenting and endarterectomy in the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST). Circulation. 2012 Dec 18; 126(25):3054-61. Epub 2012 Nov 16.
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Habersberger J, Brott TG, Roubin GS. Carotid artery stenting: a clinical update. Curr Opin Cardiol. 2012 Nov; 27(6):565-71.
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Kappetein AP, Head SJ, Genereux P, Piazza N, van Mieghem NM, Blackstone EH, Brott TG, Cohen DJ, Cutlip DE, van Es GA, Hahn RT, Kirtane AJ, Krucoff MW, Kodali S, Mack MJ, Mehran R, Rodes-Cabau J, Vranckx P, Webb JG, Windecker S, Serruys PW, Leon MB, Valve Academic Research Consortium (VARC)-2. Updated standardized endpoint definitions for transcatheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document (VARC-2). Eur J Cardiothorac Surg. 2012 Nov; 42(5):S45-60. Epub 2012 Oct 1
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Holliday EG, Maguire JM, Evans TJ, Koblar SA, Jannes J, Sturm JW, Hankey GJ, Baker R, Golledge J, Parsons MW, Malik R, McEvoy M, Biros E, Lewis MD, Lincz LF, Peel R, Oldmeadow C, Smith W, Moscato P, Barlera S, Bevan S, Bis JC, Boerwinkle E, Boncoraglio GB, Brott TG, Brown RD Jr, Cheng YC, Cole JW, Cotlarciuc I, Devan WJ, Fornage M, Furie KL, Gretarsdottir S, Gschwendtner A, Ikram MA, Longstreth WT Jr, Meschia JF, Mitchell BD, Mosley TH, Nalls MA, Parati EA, Psaty BM, Sharma P, Stefansson K, Thorleifsson G, Thorsteinsdottir U, Traylor M, Verhaaren BF, Wiggins KL, Worrall BB, Sudlow C, Rothwell PM, Farrall M, Dichgans M, Rosand J, Markus HS, Scott RJ, Levi C, Attia J, Australian Stroke Genetics Collaborative, International Stroke Genetics Consortium, Wellcome Trust Case Control Consortium 2. Common variants at 6p21.1 are associated with large artery atherosclerotic stroke. Nat Genet. 2012 Oct; 44(10):1147-51. Epub 2012 Sep 02.
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Vilain KR, Magnuson EA, Li H, Clark WM, Begg RJ, Sam AD 2nd, Sternbergh WC 3rd, Weaver FA, Gray WA, Voeks JH, Brott TG, Cohen DJ, CREST Investigators. Costs and cost-effectiveness of carotid stenting versus endarterectomy for patients at standard surgical risk: results from the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST). Stroke. 2012 Sep; 43(9):2408-16. Epub 2012 Jul 19.
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Lal BK, Beach KW, Roubin GS, Lutsep HL, Moore WS, Malas MB, Chiu D, Gonzales NR, Burke JL, Rinaldi M, Elmore JR, Weaver FA, Narins CR, Foster M, Hodgson KJ, Shepard AD, Meschia JF, Bergelin RO, Voeks JH, Howard G, Brott TG, CREST Investigators. Restenosis after carotid artery stenting and endarterectomy: a secondary analysis of CREST, a randomised controlled trial. Lancet Neurol. 2012 Sep; 11 (9):755-63 Epub 2012 Aug 02
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Longbottom ME, Roberts JN, Tom M, Hughes SE, Howard VJ, Sheffet AJ, Meschia JF, Brott TG, CREST Investigators. Interventions to increase enrollment in a large multicenter phase 3 trial of carotid stenting vs. endarterectomy. Int J Stroke. 2012 Aug; 7 (6):447-53 Epub 2012 May 28
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Cheng YC, Anderson CD, Bione S, Keene K, Maguire JM, Nalls M, Rasheed A, Zeginigg M, Attia J, Baker R, Barlera S, Biffi A, Bookman E, Brott TG, Brown RD Jr, Chen F, Chen WM, Ciusani E, Cole JW, Cortellini L, Danesh J, Doheny K, Ferrucci L, Grazia Franzosi M, Frossard P, Furie KL, Golledge J, Hankey GJ, Hernandez D, Holliday EG, Hsu FC, Jannes J, Kamal A, Khan MS, Kittner SJ, Koblar SA, Lewis M, Lincz L, Lisa A, Matarin M, Moscato P, Mychaleckyj JC, Parati EA, Parolo S, Pugh E, Rost NS, Schallert M, Schmidt H, Scott RJ, Sturm JW, Yadav S, Zaidi M, Boncoraglio GB, Levi CR, Meschia JF, Rosand J, Sale M, Saleheen D, Schmidt R, Sharma P, Worrall B, Mitchell BD, GARNET Collaborative Research Group, GENEVA Consortium, International Stroke Genetics Consortium. Are myocardial infarction--associated single-nucleotide polymorphisms associated with ischemic stroke? Stroke. 2012 Apr; 43(4):980-6. Epub 2012 Feb 23.
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Voeks JH, Howard G, Roubin GS, Malas MB, Cohen DJ, Sternbergh WC 3rd, Aronow HD, Eskandari MK, Sheffet AJ, Lal BK, Meschia JF, Brott TG, CREST Investigators. Age and outcomes after carotid stenting and endarterectomy: the carotid revascularization endarterectomy versus stenting trial. Stroke. 2011 Dec; 42(12):3484-90. Epub 2011 Oct 06.
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Cheng YC, O'Connell JR, Cole JW, Stine OC, Dueker N, McArdle PF, Sparks MJ, Shen J, Laurie CC, Nelson S, Doheny KF, Ling H, Pugh EW, Brott TG, Brown RD Jr, Meschia JF, Nalls M, Rich SS, Worrall B, Anderson CD, Biffi A, Cortellini L, Furie KL, Rost NS, Rosand J, Manolio TA, Kittner SJ, Mitchell BD. Genome-wide association analysis of ischemic stroke in young adults. G3 (Bethesda). 2011 Nov; 1(6):505-14. Epub 2011 Nov 01.
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Cohen DJ, Stolker JM, Wang K, Magnuson EA, Clark WM, Demaerschalk BM, Sam AD Jr, Elmore JR, Weaver FA, Aronow HD, Goldstein LB, Roubin GS, Howard G, Brott TG, CREST Investigators. Health-related quality of life after carotid stenting versus carotid endarterectomy: results from CREST (Carotid Revascularization Endarterectomy Versus Stenting Trial). J Am Coll Cardiol. 2011 Oct 4; 58(15):1557-65.
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Meschia JF, Nalls M, Matarin M, Brott TG, Brown RD Jr, Hardy J, Kissela B, Rich SS, Singleton A, Hernandez D, Ferrucci L, Pearce K, Keller M, Worrall BB, Siblings With Ischemic Stroke Study Investigators. Siblings with ischemic stroke study: results of a genome-wide scan for stroke loci. Stroke. 2011 Oct; 42 (10):2726-32 Epub 2011 Sept 22
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Brott TG, Halperin JL, Abbara S, Bacharach JM, Barr JD, Bush RL, Cates CU, Creager MA, Fowler SB, Friday G, Hertzberg VS, McIff EB, Moore WS, Panagos PD, Riles TS, Rosenwasser RH, Taylor AJ, American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines//American Stroke Association//American Association of Neuroscience Nurses//American Association of Neurological Surgeons//American College of Radiology//American Society of Neuroradiology//Congre. 2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS guideline on the management of patients with extracranial carotid and vertebral artery disease: executive summary. Stroke. 2011 Aug; 42 (8):e420-63 Epub 2011 Jan 31
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Brott TG, Halperin JL, Abbara S, Bacharach JM, Barr JD, Bush RL, Cates CU, Creager MA, Fowler SB, Friday G, Hertzberg VS, McIff EB, Moore WS, Panagos PD, Riles TS, Rosenwasser RH, Taylor AJ, American College of Cardiology Foundation//American Stroke Association//American Association of Neurological Surgeons//American College of Radiology//American Society of Neuroradiology//Congress of Neurological Surgeons//Society of Atherosclerosis Imaging and Prevention//Society for Cardiovascular. 2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS guideline on the management of patients with extracranial carotid and vertebral artery disease: executive summary. A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American Stroke Association, American Association of Neuroscience Nurses, American Association of Neurological Surgeons, American College of Radiology, American Society of Neuroradiology, Congress of N Circulation. 2011 Jul 26; 124 (4):489-532 Epub 2011 Jan 31
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Brott TG, Halperin JL, Abbara S, Bacharach JM, Barr JD, Bush RL, Cates CU, Creager MA, Fowler SB, Friday G, Hertzberg VS, McIff EB, Moore WS, Panagos PD, Riles TS, Rosenwasser RH, Taylor AJ, American College of Cardiology//American Stroke Association//American Association of Neurological Surgeons//American College of Radiology//American American College of Radiology//Society of NeuroInterventional Surgery//Society for Vascular Medicine//Society for Vascular Surgery. 2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS guideline on the management of patients with extracranial carotid and vertebral artery disease. A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American Stroke Association, American Association of Neuroscience Nurses, American Association of Neurological Surgeons, American College of Radiology, American Society of Neuroradiology, Congress of Neurological Surgeon Circulation. 2011 Jul 26; 124 (4):e54-130 Epub 2011 Jan 31
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Aguilar MI, Brott TG. Update in intracerebral hemorrhage. Neurohospitalist. 2011 Jul; 1 (3):148-59
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Blackshear JL, Cutlip DE, Roubin GS, Hill MD, Leimgruber PP, Begg RJ, Cohen DJ, Eidt JF, Narins CR, Prineas RJ, Glasser SP, Voeks JH, Brott TG, CREST Investigators. Myocardial infarction after carotid stenting and endarterectomy: results from the carotid revascularization endarterectomy versus stenting trial. Circulation. 2011 Jun 7; 123 (22):2571-8 Epub 2011 May 23
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Howard VJ, Lutsep HL, Mackey A, Demaerschalk BM, Sam AD 2nd, Gonzales NR, Sheffet AJ, Voeks JH, Meschia JF, Brott TG, CREST investigators. Influence of sex on outcomes of stenting versus endarterectomy: a subgroup analysis of the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST). Lancet Neurol. 2011 Jun; 10(6):530-7. Epub 2011 May 5.
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Brott TG, Halperin JL, Abbara S, Bacharach JM, Barr JD, Bush RL, Cates CU, Creager MA, Fowler SB, Friday G, Hertzberg VS, McIff EB, Moore WS, Panagos PD, Riles TS, Rosenwasser RH, Taylor AJ, American College of Cardiology Foundation/American Heart Association Task Force//American Stroke Association//American Association of Neuroscience Nurses//American Association of Neurological Surgeons//American College of Radiology//American Society of Neuroradiology//Congress of Neurological Surg. 2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS guideline on the management of patients with extracranial carotid and vertebral artery disease: executive summary. J Neurointerv Surg. 2011 Jun; 3 (2):100-30
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Barrett KM, Brott TG, Brown RD Jr, Carter RE, Geske JR, Graff-Radford NR, McNeil RB, Meschia JF, Mayo Acute Stroke Trial for Enhancing Recovery (MASTER) Study Group. Enhancing recovery after acute ischemic stroke with donepezil as an adjuvant therapy to standard medical care: results of a phase IIA clinical trial. J Stroke Cerebrovasc Dis. 2011 May-Jun; 20 (3):177-82 Epub 2011 Feb 03
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Anderson CD, Biffi A, Rahman R, Ross OA, Jagiella JM, Kissela B, Cole JW, Cortellini L, Rost NS, Cheng YC, Greenberg SM, de Bakker PI, Brown RD Jr, Brott TG, Mitchell BD, Broderick JP, Worrall BB, Furie KL, Kittner SJ, Woo D, Slowik A, Meschia JF, Saxena R, Rosand J, International Stroke Genetics Consortium. Common mitochondrial sequence variants in ischemic stroke. Ann Neurol. 2011 Mar; 69(3):471-80. Epub 2010 Sep 13.
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Silver FL, Mackey A, Clark WM, Brooks W, Timaran CH, Chiu D, Goldstein LB, Meschia JF, Ferguson RD, Moore WS, Howard G, Brott TG, CREST Investigators. Safety of stenting and endarterectomy by symptomatic status in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST). Stroke. 2011 Mar; 42(3):675-80. Epub 2011 Feb 09.
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Brott TG, Halperin JL, Abbara S, Bacharach JM, Barr JD, Bush RL, Cates CU, Creager MA, Fowler SB, Friday G, Hertzberg VS, McIff EB, Moore WS, Panagos PD, Riles TS, Rosenwasser RH, Taylor AJ. 2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS guideline on the management of patients with extracranial carotid and vertebral artery disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American Stroke Association, American Association of Neuroscience Nurses, American Association of Neurological Surgeons, American College of Radiology, American Society of Neuroradiology, Congress of Neurological Surgeon J Am Coll Cardiol. 2011 Feb 22; 57 (8):e16-94 Epub 2011 Feb 01
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Brott TG, Halperin JL, Abbara S, Bacharach JM, Barr JD, Bush RL, Cates CU, Creager MA, Fowler SB, Friday G, Hertzberg VS, McIff EB, Moore WS, Panagos PD, Riles TS, Rosenwasser RH, Taylor AJ. 2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS guideline on the management of patients with extracranial carotid and vertebral artery disease: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American Stroke Association, American Association of Neuroscience Nurses, American Association of Neurological Surgeons, American College of Radiology, American Society of Neuroradiology, Congress of N J Am Coll Cardiol. 2011 Feb 22; 57 (8):1002-44 Epub 2011 Feb 01
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Brott TG, Halperin JL, Abbara S, Bacharach JM, Barr JD, Bush RL, Cates CU, Creager MA, Fowler SB, Friday G, Hertzberg VS, McIff EB, Moore WS, Panagos PD, Riles TS, Rosenwasser RH, Taylor AJ, American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines//American Stroke Association//American Association of Neuroscience Nurses//American Association of Neurological Surgeons//American College of Radiology//American Society of Neuroradiology//Congre. 2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/ SCAI/SIR/SNIS/SVM/SVS guideline on the management of patients with extracranial carotid and vertebral artery disease: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American Stroke Association, American Association of Neuroscience Nurses, American Association of Neurological Surgeons, American College of Radiology, American Society of Neuroradiology, Congress of Vasc Med. 2011 Feb; 16 (1):35-77
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Brott T, Halperin J, Abbara S, Bacharach JM, Barr J, Bush R, Cates C, Creager M, Fowler S, Friday G, Hertzberg V, McIff B, Moore W, Panago P, Riles T, Rosenwasser R, Taylor A. ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS Guideline on the Management of Patients With Extracranial Carotid and Vertebral Artery Disease Stroke.2011;
Meschia JF, Singleton A, Nalls MA, Rich SS, Sharma P, Ferrucci L, Matarin M, Hernandez DG, Pearce K, Brott TG, Brown RD Jr, Hardy J, Worrall BB. Genomic risk profiling of ischemic stroke: results of an international genome-wide association meta-analysis. PLoS One. 2011; 6 (9):e23161 Epub 2011 Sept 21
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Meschia JF, Nalls M, Matarin M, Brott TG, Brown RD, Hardy J, Kissela B, Rich S, Singleton A, Hernandez D, Ferrucci L, Pearce K, Keller M, Worrall B. Revised: Siblings with Ischemic Stroke Study (SWISS): Results of a Genome-wide Scan for Stroke Loci Stroke. 2011.
Perkins WJ, Lanzino G, Brott TG. Carotid stenting vs endarterectomy: new results in perspective. Mayo Clin Proc. 2010 Dec; 85 (12):1101-8
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Rost NS, Rahman RM, Biffi A, Smith EE, Kanakis A, Fitzpatrick K, Lima F, Worrall BB, Meschia JF, Brown RD Jr, Brott TG, Sorensen AG, Greenberg SM, Furie KL, Rosand J. White matter hyperintensity volume is increased in small vessel stroke subtypes. Neurology. 2010 Nov 9; 75(19):1670-7.
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Barrett KM, Brott TG. Management of stenosis of the extracranial internal carotid artery: endarterectomy versus angioplasty and stenting. Curr Treat Options Neurol. 2010 Nov; 12 (6):475-82
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Mantese VA, Timaran CH, Chiu D, Begg RJ, Brott TG, CREST Investigators. The Carotid Revascularization Endarterectomy versus Stenting Trial (CREST): stenting versus carotid endarterectomy for carotid disease. Stroke. 2010 Oct; 41 (10 Suppl):S31-4
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Brott TG, Hobson RW 2nd, Howard G, Roubin GS, Clark WM, Brooks W, Mackey A, Hill MD, Leimgruber PP, Sheffet AJ, Howard VJ, Moore WS, Voeks JH, Hopkins LN, Cutlip DE, Cohen DJ, Popma JJ, Ferguson RD, Cohen SN, Blackshear JL, Silver FL, Mohr JP, Lal BK, Meschia JF, CREST Investigators. Stenting versus endarterectomy for treatment of carotid-artery stenosis. N Engl J Med. 2010 Jul 1; 363 (1):11-23 Epub 2010 May 26
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Rush BK, McNeil RB, Gamble DM, Luke SH, Richie AN, Albers CS, Brown RD, Brott TG, Meschia JF. Behavioral symptoms in long-term survivors of ischemic stroke. J Stroke Cerebrovasc Dis. 2010 Jul-Aug; 19(4):326-32.
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Meschia JF, McNeil RB, Barrett KM, Brott TG, Graff-Radford NR, Brown RD Jr. Mayo Acute Stroke Trial for Enhancing Recovery (MASTER) protocol. J Stroke Cerebrovasc Dis. 2010 Jul-Aug; 19 (4):299-310
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Lees KR, Bluhmki E, von Kummer R, Brott TG, Toni D, Grotta JC, Albers GW, Kaste M, Marler JR, Hamilton SA, Tilley BC, Davis SM, Donnan GA, Hacke W, ECASS, ATLANTIS, NINDS and EPITHET rt-PA Study Group, Allen K, Mau J, Meier D, del Zoppo G, De Silva DA, Butcher KS, Parsons MW, Barber PA, Levi C, Bladin C, Byrnes G. Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials. Lancet. 2010 May 15; 375(9727):1695-703.
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Hopkins LN, Roubin GS, Chakhtoura EY, Gray WA, Ferguson RD, Katzen BT, Rosenfield K, Goldstein J, Cutlip DE, Morrish W, Lal BK, Sheffet AJ, Tom M, Hughes S, Voeks J, Kathir K, Meschia JF, Hobson RW II, Brott TG. The Carotid Revascularization Endarterectomy versus Stenting Trial: credentialing of interventionalists and final results of lead-in phase. J Stroke Cerebrovasc Dis. 2010 Mar; 19(2):153-62.
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Sheffet AJ, Roubin G, Howard G, Howard V, Moore W, Meschia JF, Hobson RW, Brott TG. Design of the Carotid Revascularization Endarterectomy vs. Stenting Trial (CREST). Int J Stroke. 2010 Feb; 5(1):40-6.
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Matarin M, Brown WM, Dena H, Britton A, De Vrieze FW, Brott TG, Brown RD Jr, Worrall BB, Case LD, Chanock SJ, Metter EJ, Ferruci L, Gamble D, Hardy JA, Rich SS, Singleton A, Meschia JF. Candidate gene polymorphisms for ischemic stroke. Stroke. 2009 Nov; 40(11):3436-42. Epub 2009 Sep 03.
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Lal BK, Brott TG. The Carotid Revascularization Endarterectomy vs. Stenting Trial completes randomization: lessons learned and anticipated results. J Vasc Surg. 2009 Nov; 50(5):1224-31.
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Richie AN, Trejo J, Bowers CG, McNeil RB, Gamble DM, Luke SH, Brown RD Jr, Brott TG, Kissela BM, Worrall BB, Meschia JF, SWISS Group. Joint Commission primary stroke center certification does not affect proband enrollment: the siblings with ischemic stroke study. J Stroke Cerebrovasc Dis. 2009 Sep-Oct; 18 (5):363-6
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Stroud N, Mazwi TM, Case LD, Brown RD Jr, Brott TG, Worrall BB, Meschia JF, Ischemic Stroke Genetics Study Investigators. Prestroke physical activity and early functional status after stroke. J Neurol Neurosurg Psychiatry. 2009 Sep; 80 (9):1019-22 Epub 2009 July 14
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Howard VJ, Voeks JH, Lutsep HL, Mackey A, Milot G, Sam AD 2nd, Tom M, Hughes SE, Sheffet AJ, Longbottom M, Avery JB, Hobson RW 2nd, Brott TG. Does sex matter? Thirty-day stroke and death rates after carotid artery stenting in women versus men: results from the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST) lead-in phase. Stroke. 2009 Apr; 40(4):1140-7. Epub 2009 Feb 10.
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Pancioli AM, Broderick J, Brott T, Tomsick T, Khoury J, Bean J, del Zoppo G, Kleindorfer D, Woo D, Khatri P, Castaldo J, Frey J, Gebel J Jr, Kasner S, Kidwell C, Kwiatkowski T, Libman R, Mackenzie R, Scott P, Starkman S, Thurman RJ, CLEAR Trial Investigators. The combined approach to lysis utilizing eptifibatide and rt-PA in acute ischemic stroke: the CLEAR stroke trial. Stroke. 2008 Dec; 39(12):3268-76. Epub 2008 Sep 04.
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Chen DT, Meschia JF, Brott TG, Brown RD, Worrall BB, Siblings with Ischemic Stroke Study Investigators. Stroke genetic research and adults with impaired decision-making capacity: a survey of IRB and investigator practices. Stroke. 2008 Oct; 39(10):2732-5. Epub 2008 Jul 24.
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Kissela BM, Brott TG, Brown RD Jr, Silliman SL, Brown WM, Rich SS, Meschia JF. Proband race/ethnicity affects pedigree completion rate in a genetic study of ischemic stroke. J Stroke Cerebrovasc Dis. 2008 Sep; 17(5):299-302.
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Barrett KM, Brott TG. Carotid artery stenting versus carotid endarterectomy: current status. Neurosurg Clin N Am. 2008 Jul; 19(3):447-58, vi.
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Falkensammer J, Oldenburg WA, Hendrzak AJ, Neuhauser B, Pedraza O, Ferman T, Klocker J, Biebl M, Hugl B, Meschia JF, Hakaim AG, Brott TG. Evaluation of subclinical cerebral injury and neuropsychologic function in patients undergoing carotid endarterectomy. Ann Vasc Surg. 2008 Jul-Aug; 22 (4):497-504 Epub 2008 May 27
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Matarin M, Simon-Sanchez J, Fung HC, Scholz S, Gibbs JR, Hernandez DG, Crews C, Britton A, De Vrieze FW, Brott TG, Brown RD Jr, Worrall BB, Silliman S, Case LD, Hardy JA, Rich SS, Meschia JF, Singleton AB. Structural genomic variation in ischemic stroke. Neurogenetics. 2008 May; 9(2):101-8. Epub 2008 Feb 21.
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Nichols C, Khoury J, Brott T, Broderick J. Intravenous recombinant tissue plasminogen activator improves arterial recanalization rates and reduces infarct volumes in patients with hyperdense artery sign on baseline computed tomography. J Stroke Cerebrovasc Dis. 2008 Mar-Apr; 17(2):64-8.
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Chen DT, Case LD, Brott TG, Brown RD Jr, Silliman SL, Meschia JF, Worrall BB, ISGS Investigators. Impact of restricting enrollment in stroke genetics research to adults able to provide informed consent. Stroke. 2008 Mar; 39(3):831-7. Epub 2008 Feb 07.
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Freeman WD, Barrett KM, Bestic JM, Meschia JF, Broderick DF, Brott TG. Computer-assisted volumetric analysis compared with ABC/2 method for assessing warfarin-related intracranial hemorrhage volumes. Neurocrit Care. 2008; 9 (3):307-12
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Matarin M, Brown WM, Hardy JA, Rich SS, Singleton AB, Brown RD Jr, Brott TG, Worrall BB, Meschia JF, SWISS Study Group, ISGS Study Group, MSGD Study Group. Association of integrin alpha2 gene variants with ischemic stroke. J Cereb Blood Flow Metab. 2008 Jan; 28(1):81-9. Epub 2007 May 30.
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Barrett KM, Brott TG. Carotid endarterectomy versus angioplasty/stenting for carotid stenosis. Curr Atheroscler Rep. 2007 Oct; 9 (4):333-40
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Leslie-Mazwi TM, Brott TG, Brown RD Jr, Worrall BB, Silliman SL, Case LD, Frankel MR, Rich SS, Meschia JF. Sex differences in stroke evaluations in the Ischemic Stroke Genetics Study. J Stroke Cerebrovasc Dis. 2007 Sep-Oct; 16 (5):187-93
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Thompson KM, Gerlach SY, Jorn HK, Larson JM, Brott TG, Files JA. Advances in the care of patients with intracerebral hemorrhage. Mayo Clin Proc. 2007 Aug; 82: (8)987-90.
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Barrett KM, Freeman WD, Weindling SM, Brott TG, Broderick DF, Heckman MG, Crook JE, Divertie GD, Meschia JF. Brain injury after cardiopulmonary arrest and its assessment with diffusion-weighted magnetic resonance imaging. Mayo Clin Proc. 2007 Jul; 82(7):828-35.
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Meschia JF, Brott TG, Hobson RW 2nd. Diagnosis and invasive management of carotid atherosclerotic stenosis. Mayo Clin Proc. 2007 Jul; 82 (7):851-8
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Matarin M, Brown WM, Scholz S, Simon-Sanchez J, Fung HC, Hernandez D, Gibbs JR, De Vrieze FW, Crews C, Britton A, Langefeld CD, Brott TG, Brown RD Jr, Worrall BB, Frankel M, Silliman S, Case LD, Singleton A, Hardy JA, Rich SS, Meschia JF. A genome-wide genotyping study in patients with ischaemic stroke: initial analysis and data release. Lancet Neurol. 2007 May; 6(5):414-20.
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Worrall BB, Brott TG, Brown RD Jr, Brown WM, Rich SS, Arepalli S, Wavrant-De Vrieze F, Duckworth J, Singleton AB, Hardy J, Meschia JF, SWISS ISGS and MSGD I. IL1RN VNTR polymorphism in ischemic stroke: analysis in 3 populations. Stroke. 2007 Apr; 38(4):1189-96.
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Wiklund PG, Brown WM, Brott TG, Stegmayr B, Brown RD, Nilsson-Ardnor S, Hardy JA, Kissela BM, Singleton A, Holmberg D, Rich SS, Meschia JF. Lack of aggregation of ischemic stroke subtypes within affected sibling pairs. Neurology. 2007 Feb 6; 68(6):427-31.
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Brott TG. Novel approaches to stroke prevention in atrial fibrillation: introduction. Stroke. 2007 Feb; 38: (2 Suppl)614.
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Barrett KM, Brott TG, Brown RD Jr, Frankel MR, Worrall BB, Silliman SL, Case LD, Rich SS, Meschia JF, Ischemic Stroke Genetics Study Group. Sex differences in stroke severity, symptoms, and deficits after first-ever ischemic stroke. J Stroke Cerebrovasc Dis. 2007 Jan-Feb; 16 (1):34-9
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Barrett KM, Brott TG. Carotid artery stenting versus carotid endarterectomy: current status. Neurol Clin. 2006 Nov; 24(4):681-95.
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Meschia JF, Barrett KM, Chukwudelunzu F, Brown WM, Case LD, Kissela BM, Brown RD Jr, Brott TG, Olson TS, Rich SS, Silliman S, Worrall BB, Siblings with Ischemic Stroke Study (SWISS) Investigators. Interobserver agreement in the trial of org 10172 in acute stroke treatment classification of stroke based on retrospective medical record review. J Stroke Cerebrovasc Dis. 2006 Nov-Dec; 15 (6):266-72
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Meschia JF, Case LD, Worrall BB, Brown RD Jr, Brott TG, Frankel M, Silliman S, Rich SS, Ischemic Stroke Genetics Study Group. Family history of stroke and severity of neurologic deficit after stroke. Neurology. 2006 Oct 24; 67 (8):1396-402
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Jauch EC, Lindsell CJ, Adeoye O, Khoury J, Barsan W, Broderick J, Pancioli A, Brott T. Lack of evidence for an association between hemodynamic variables and hematoma growth in spontaneous intracerebral hemorrhage. Stroke. 2006 Aug; 37(8):2061-5. Epub 2006 Jun 22.
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He Z, Meschia JF, Brott TG, Dickson DW, McKinney M, McKinney M. Aging is neuroprotective during global ischemia but leads to increased caspase-3 and apoptotic activity in hippocampal neurons. Curr Neurovasc Res. 2006 Aug; 3 (3):181-6
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Levy JH, Fingerhut A, Brott T, Langbakke IH, Erhardtsen E, Porte RJ. Recombinant factor VIIa in patients with coagulopathy secondary to anticoagulant therapy, cirrhosis, or severe traumatic injury: review of safety profile. Transfusion. 2006 Jun; 46(6):919-33.
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Dominguez R, Vila JF, Augustovski F, Irazola V, Castillo PR, Rotta Escalante R, Brott TG, Meschia JF. Spanish cross-cultural adaptation and validation of the National Institutes of Health Stroke Scale. Mayo Clin Proc. 2006 Apr; 81(4):476-80.
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Meschia JF, Kissela BM, Brott TG, Brown RD Jr, Worrall BB, Beck J, Skarp AN. The Siblings With Ischemic Stroke Study (SWISS): a progress report. Clin Med Res. 2006 Mar; 4 (1):12-21
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Freeman WD, Brott TG. Modern treatment options for intracerebral hemorrhage. Curr Treat Options Neurol. 2006 Mar; 8 (2):145-57
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He Z, Crook JE, Meschia JF, Brott TG, Dickson DW, McKinney M, McKinney M. Aging blunts ischemic-preconditioning-induced neuroprotection following transient global ischemia in rats. Curr Neurovasc Res. 2005 Dec; 2 (5):365-74
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He Z, Cui L, Meschia JF, Dickson DW, Brott TG, Simpkins JW, Day AL, McKinney M, McKinney M. Hippocampal progenitor cells express nestin following cerebral ischemia in rats. Neuroreport. 2005 Sep 28; 16 (14):1541-4
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Meschia JF, Brott TG, Brown RD Jr, Crook R, Worrall BB, Kissela B, Brown WM, Rich SS, Case LD, Evans EW, Hague S, Singleton A, Hardy J, SWISS Study Group//ISGS Study Group//MSGD Study Group. Phosphodiesterase 4D and 5-lipoxygenase activating protein in ischemic stroke. Ann Neurol. 2005 Sep; 58 (3):351-61
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Feldmann E, Broderick JP, Kernan WN, Viscoli CM, Brass LM, Brott T, Morgenstern LB, Wilterdink JL, Horwitz RI. Major risk factors for intracerebral hemorrhage in the young are modifiable. Stroke. 2005 Sep; 36(9):1881-5.
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Broderick JP, Brott T, DeGraba T, Fagan SC, Frankel MR, Grotta JC, Haley EC, Hamilton S, Kwiatkowski T, Levine SR, Lewandowski CA, Lin Y, Libman R, Lu M, Lyden P, Marler JR, Morgenstern L, Patel S, Sanders C, Tilley BC. Recombinant tissue plasminogen activator for minor strokes: The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Experience. Ann Emerg Med. 2005 Sep; 46(3):243-52.
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Hobson RW, Brott TG, Roubin GS, Silver FL, Barnett HJM. Carotid artery stenting - Meeting the recruitment challenge of a clinical trial. Stroke. 2005 Jun; 36(6):1314-5.
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Lu M, Lyden PD, Brott TG, Hamilton S, Broderick JP, Grotta JC. Beyond subgroup analysis: improving the clinical interpretation of treatment effects in stroke research. J Neurosci Methods. 2005 Apr 30; 143(2):209-16.
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Kwiatkowski T, Libman R, Tilley BC, Lewandowski C, Grotta JC, Lyden P, Levine SR, Brott T. The impact of imbalances in baseline stroke severity on outcome in the National Institute of Neurological Disorders and Stroke recombinant tissue plasminogen activator stroke study. Ann Emerg Med. 2005 Apr; 45(4):377-84.
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Meschia JF, Brott TG, Brown RD Jr, Kissela BM, Hardy JA, Brown WM, Rich SS, Siblings With Ischemic Stroke Study Investigators. Correlation of proband and sibling stroke latency: the SWISS Study. Neurology. 2005 Mar 22; 64: (6)1061-3.
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Chen DT, Worrall BB, Brown RD, Brott TG, Kissela BM, Olson TS, Rich SS, Meschia JF. The impact of privacy protections on recruitment in a multicenter stroke genetics study. Neurology. 2005 Feb 22; 64(4):721-4.
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Meschia JF, Brott TG, Brown RD. Genetics of cerebrovascular disorders. Mayo Clin Proc. 2005 Jan; 80(1):122-32.
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Worrall BB, Chen DT, Brown RD, Brott TG, Meschia JF. A survey of the SWISS researchers on the impact of sibling privacy protections on pedigree recruitment. Neuroepidemiology. 2005; 25(1):32-41.
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Hobson RW, Howard VJ, Roubin GS, Brott TG, Ferguson RD, Popma JJ, Graham DL, Howard G. Carotid artery stenting is associated with increased complications in octogenarians: 30-day stroke and death rates in the CREST lead-in phase. J Vasc Surg. 2004 Dec; 40(6):1106-10.
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Freeman WD, Brott TG, Barrett KM, Castillo PR, Deen HG Jr, Czervionke LF, Meschia JF. Recombinant factor VIIa for rapid reversal of warfarin anticoagulation in acute intracranial hemorrhage. Mayo Clin Proc. 2004 Dec; 79: (12)1495-500.
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Castillo PR, Brott TG, Alvarez S, Meschia JF. Creation of a bilingual Spanish-English version of the Questionnaire for Verifying Stroke-free Status. Neuroepidemiology. 2004 Sep-Oct; 23(5):236-9.
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Brott TG, Brown RD Jr, Meyer FB, Miller DA, Cloft HJ, Sullivan TM. Carotid revascularization for prevention of stroke: carotid endarterectomy and carotid artery stenting. Mayo Clin Proc. 2004 Sep; 79(9):1197-208.
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Brott TG. Carotid surgery to prevent stroke. Lancet Neurol. 2004 Aug; 3(8):452-3.
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Hacke W, Donnan G, Fieschi C, Kaste M, von Kummer R, Broderick JP, Brott T, Frankel M, Grotta JC, Haley EC, Kwiatkowski T, Levine SR, Lewandowski C, Lu M, Lyden P, Marler JR, Patel S, Tilley BC, Albers G, Grotta J, Bluhmki PE, Wilhelm M, Hamilton S. Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials. Lancet. 2004 Mar 6; 363(9411):768-74.
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Meschia JF, Lojacono MA, Miller MJ, Brott TG, Atkinson EJ, O'Brien PC. Reliability of the questionnaire for verifying stroke-free status. Cerebrovasc Dis. 2004; 17 (2-3):218-23 Epub 2003 Dec 29
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Pancioli AM, Brott TG. Therapeutic potential of platelet glycoprotein IIb/IIIa receptor antagonists in acute ischaemic stroke - Scientific rationale and available evidence. CNS Drugs. 2004; 18(14):981-8.
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Hobson RW, Howard VJ, Roubin GS, Ferguson RD, Brott TG, Howard G, Sheffet AJ, Roberts J, Hopkins LN, Moore WS for the CREST Investigators. Credentialing of surgeons as interventionalists for carotid artery stenting: Experience from the lead-in phase of Crest. The Society for Vascular Surgery. 2004.08; 40:952-7.
Meschia JF, Brott TG, Brown RD Jr, Crook RJ, Frankel M, Hardy J, Merino JG, Rich SS, Silliman S, Worrall BB, Ischemic Stroke Genetics Study. The Ischemic Stroke Genetics Study (ISGS) Protocol. BMC Neurol. 2003 Jul 8; 3:4 Epub 2003 July 08
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Meschia JF, Atkinson EJ, O'Brien PC, Brott TG, Brown RD Jr, Hardy J. Familial clustering of stroke according to proband age at onset of presenting ischemic stroke. Stroke. 2003 Jul; 34: (7)e89-91.
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Worrall BB, Brown DL, Brott TG, Brown RD, Silliman SL, Meschia JF. Spouses and unrelated friends of probands as controls for stroke genetics studies. Neuroepidemiology. 2003 Jul-Aug; 22(4):239-44.
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Broderick JP, Viscoli CM, Brott T, Kernan WN, Brass LM, Feldmann E, Morgenstern LB, Wilterdink JL, Horwitz RI. Major risk factors for aneurysmal subarachnoid hemorrhage in the young are modifiable. Stroke. 2003 Jun; 34(6):1375-81.
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Adams Jr HP, Adams RJ, Brott TG, del Zoppo GJ, Furlan A, Goldstein LB, Grubb RL, Higashida R, Kidwell C, Kwiatkowski TG, Marler JR, Hademenos GJ. Guidelines for the early management of patients with ischemic stroke: a scientific statement from the stroke council of the american stroke association. Stroke. 2003 Apr; 34:1056-1083.
Morgenstern LB, Viscoli CM, Kernan WN, Brass LM, Broderick JP, Feldmann E, Wilterdink JL, Brott T, Horwitz RI. Use of Ephedra-containing products and risk for hemorrhagic stroke. Neurology. 2003 Jan 14; 60(1):132-5.
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Meschia JF, Brott TG, Kotsenas AL, Dickson DW, Wharen RE Jr. Failure to wean from a ventilator caused by ANNA-1 seropositive paraneoplastic syndrome. Eur Neurol. 2003; 50 (2):112-4
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Gebel JM, Jauch EC, Brott TG, Khoury J, Sauerbeck L, Salisbury S, Spilker J, Tomsick TA, Duldner J, Broderick JP. Natural history of perihematomal edema in patients with hyperacute spontaneous intracerebral hemorrhage. Stroke. 2002 Nov; 33(11):2631-5.
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Gebel JM, Jauch EC, Brott TG, Khoury J, Sauerbeck L, Salisbury S, Spilker J, Tomsick TA, Duldner J, Broderick JP. Relative edema volume is a predictor of outcome in patients with hyperacute spontaneous intracerebral Hemorrhage. Stroke. 2002 Nov; 33(11):2636-41.
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Bruno A, Levine SR, Frankel MR, Brott TG, Lin Y, Tilley BC, Lyden PD, Broderick JP, Kwiatkowski TG, Fineberg SE. Admission glucose level and clinical outcomes in the NINDS rt-PA Stroke Trial. Neurology. 2002 Sep 10; 59(5):669-74.
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Meschia JF, Miller DA, Brott TG. Thrombolytic treatment of acute ischemic stroke. Mayo Clin Proc. 2002 Jun; 77: (6)542-51.
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Meschia JF, Brott TG. Thrombolysis for acute ischemic stroke: future directions. J Stroke Cerebrovasc Dis. 2002 May-Aug; 11(3-4):183-96.
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Meschia JF, Brown RD Jr, Brott TG, Chukwudelunzu FE, Hardy J, Rich SS. The Siblings With Ischemic Stroke Study (SWISS) protocol. BMC Med Genet. 2002; 3:1 Epub 2002 Feb 12
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Patel SC, Levine SR, Tilley BC, Grotta JC, Lu M, Frankel M, Haley EC Jr, Brott TG, Broderick JP, Horowitz S, Lyden PD, Lewandowski CA, Marler JR, Welch KM, National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Lack of clinical significance of early ischemic changes on computed tomography in acute stroke. JAMA. 2001 Dec 12; 286(22):2830-8.
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Lyden P, Lu M, Kwiatkowski T, Frankel M, Levine S, Broderick J, Brott T, NINDS rt-PA Stroke Study Group. Thrombolysis in patients with transient neurologic deficits. Neurology. 2001 Dec 11; 57(11):2125-8.
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Meschia JF, Brown RD Jr, Brott TG, Hardy J, Atkinson EJ, O'Brien PC. Feasibility of an affected sibling pair study in ischemic stroke: results of a 2-center family history registry. Stroke. 2001 Dec 1; 32 (12):2939-41
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Brott TG. Seven out of 10 stroke patients suffer disability or death: how to beat the odds. Bottom Line/Health. 2001 Aug; 15(8):3-4.
Broderick J, Lu M, Jackson C, Pancioli A, Tilley BC, Fagan SC, Kothari R, Levine SR, Marler JR, Lyden PD, Haley EC Jr, Brott T, Grotta JC, NINDS t-PA Stroke Study Group. Apolipoprotein E phenotype and the efficacy of intravenous tissue plasminogen activator in acute ischemic stroke. Ann Neurol. 2001 Jun; 49(6):736-44.
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Kissela B, Broderick J, Woo D, Kothari R, Miller R, Khoury J, Brott T, Pancioli A, Jauch E, Gebel J, Shukla R, Alwell K, Tomsick T. Greater Cincinnati/Northern Kentucky Stroke Study: volume of first-ever ischemic stroke among blacks in a population-based study. Stroke. 2001 Jun; 32(6):1285-90.
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Lyden PD, Lu M, Levine SR, Brott TG, Broderick J, NINDS rtPA Stroke Study Group. A modified National Institutes of Health Stroke Scale for use in stroke clinical trials: preliminary reliability and validity. Stroke. 2001 Jun; 32(6):1310-7.
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Kothari RU, Hacke W, Brott T, Dykstra EH, Furlan A, Koroshetz W, Marler J, Sayre MR. Stroke. Ann Emerg Med. 2001 Apr; 37(4 Suppl S):S137-S144.
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Derex L, Tomsick TA, Brott TG, Lewandowski CA, Frankel MR, Clark W, Starkman S, Spilker J, Udsten GJ, Khoury J, Grotta JC, Broderick JP, EMS Bridging Trial. Outcome of stroke patients without angiographically revealed arterial occlusion within four hours of symptom onset. AJNR Am J Neuroradiol. 2001 Apr; 22(4):685-90.
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Grotta JC, Welch KM, Fagan SC, Lu M, Frankel MR, Brott T, Levine SR, Lyden PD. Clinical deterioration following improvement in the NINDS rt-PA Stroke Trial. Stroke. 2001 Mar; 32(3):661-8.
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Meschia JF, Brott TG. New insights on thrombolytic treatment of acute ischemic stroke. Curr Neurol Neurosci Rep. 2001 Jan; 1 (1):19-25
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Kernan WN, Viscoli CM, Brass LM, Broderick JP, Brott T, Feldmann E, Morgenstern LB, Wilterdink JL, Horwitz RI. Phenylpropanolamine and the risk of hemorrhagic stroke. N Engl J Med. 2000 Dec 21; 343(25):1826-32.
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Bederson JB, Awad IA, Wiebers DO, Piepgras D, Haley EC Jr, Brott T, Hademenos G, Chyatte D, Rosenwasser R, Caroselli C. Recommendations for the management of patients with unruptured intracranial aneurysms: A Statement for healthcare professionals from the Stroke Council of the American Heart Association. Stroke. 2000 Nov; 31(11):2742-50.
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Bederson JB, Awad IA, Wiebers DO, Piepgras D, Haley EC Jr, Brott T, Hademenos G, Chyatte D, Rosenwasser R, Caroselli C. Recommendations for the management of patients with unruptured intracranial aneurysms: A statement for healthcare professionals from the Stroke Council of the American Heart Association. Circulation. 2000 Oct 31; 102(18):2300-8.
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Frankel MR, Morgenstern LB, Kwiatkowski T, Lu M, Tilley BC, Broderick JP, Libman R, Levine SR, Brott T. Predicting prognosis after stroke: a placebo group analysis from the National Institute of Neurological Disorders and Stroke rt-PA Stroke Trial. Neurology. 2000 Oct 10; 55(7):952-9.
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Broderick JP, Lu M, Kothari R, Levine SR, Lyden PD, Haley EC, Brott TG, Grotta J, Tilley BC, Marler JR, Frankel M. Finding the most powerful measures of the effectiveness of tissue plasminogen activator in the NINDS tPA stroke trial. Stroke. 2000 Oct; 31(10):2335-41.
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Brott T, Bogousslavsky J. Treatment of acute ischemic stroke. N Engl J Med. 2000 Sep 7; 343 (10):710-22
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Meschia JF, Brott TG, Chukwudelunzu FE, Hardy J, Brown RD Jr, Meissner I, Hall LJ, Atkinson EJ, O'Brien PC. Verifying the stroke-free phenotype by structured telephone interview. Stroke. 2000 May; 31 (5):1076-80
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Gebel JM, Brott TG, Sila CA, Tomsick TA, Jauch E, Salisbury S, Khoury J, Miller R, Pancioli A, Duldner JE, Topol EJ, Broderick JP. Decreased perihematomal edema in thrombolysis-related intracerebral hemorrhage compared with spontaneous intracerebral hemorrhage. Stroke. 2000 Mar; 31(3):596-600.
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Adams HP, Bogousslavsky J, Barnathan E, Brott T, Fisher M, Furlan AJ, Graffagnino C, Kappelle J, Kothari R, Leclerc JR, Moulin T, Polzer J, Torner J, Worley S, Haley CE, Day JH, Levine SR, Thompson JLP, Sherman DG, Sane DC, Maley JE, Grimsman KJ, Maeder M, Clarke WR, Anderson K. Abciximab in acute ischemic stroke - a randomized, double blind, placebo-controlled, dose-escalation study. Stroke. 2000 Mar;31(3):601-9.
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Meschia JF, Brott TG, Hardy J, Brown RD Jr, Dodick DW, Cornwell KB. Genome-wide screen for stroke: pilot testing in the siblings with ischemic stroke study (SWISS). Journal of Stroke and Cerebrovascular Diseases. 2000; 9(6):276-81.
Marler JR, Tilley BC, Lu M, Brott TG, Lyden PC, Grotta JC, Broderick JP, Levine SR, Frankel MP, Horowitz SH, Haley EC Jr, Lewandowski CA, Kwiatkowski TP. Early stroke treatment associated with better outcome: the NINDS rt-PA stroke study. Neurology. 2000; 55:1649-55.
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Grotta J, Welch K, Fagan S, Lu M, Frankel M, Brott T, Levine S, Lyden P, the NINDS rt-PA Stroke Study Group. Clinical deterioration following improvement in the NINDS rt-PA Stroke Trial. Stroke. 2000; 32:1310-7.
Lyden P, Lu M, Levine S, Brott T, Broderick J, the NINDS rt-PA Stroke Trial Investigators. A modified National Institutes of Health Stroke Scale for use in stroke clinical trials. Stroke. 2000; 32:661-8.
Lewandowski CA, Frankel M, Tomsick TA, Broderick J, Frey J, Clark W, Starkman S, Grotta J, Spilker J, Khoury J, Brott T. Combined intravenous and intra-arterial r-TPA versus intra-arterial therapy of acute ischemic stroke: Emergency Management of Stroke (EMS) Bridging Trial. Stroke. 1999 Dec; 30(12):2598-605.
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Woo D, Broderick JP, Kothari RU, Lu M, Brott T, Lyden PD, Marler JR, Grotta JC. Does the National Institutes of Health Stroke Scale favor left hemisphere strokes? Stroke. 1999 Nov; 30(11):2355-2359.
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Lyden P, Lu M, Jackson C, Marler J, Kothari R, Brott T, Zivin J. Underlying structure of the National Institutes of Health Stroke Scale: results of a factor analysis. NINDS tPA Stroke Trial Investigators. Stroke. 1999 Nov; 30(11):2347-54.
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Zuccarello M, Brott T, Derex L, Kothari R, Sauerbeck L, Tew J, Van Loveren H, Yeh HS, Tomsick T, Pancioli A, Khoury J, Broderick J. Early surgical treatment for supratentorial intracerebral hemorrhage: a randomized feasibility study. Stroke. 1999 Sep; 30(9):1833-9.
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Grotta JC, Chiu D, Lu M, Patel S, Levine SR, Tilley BC, Brott TG, Haley EC Jr, Lyden PD, Kothari R, Frankel M, Lewandowski CA, Libman R, Kwiatkowski T, Broderick JP, Marler JR, Corrigan J, Huff S, Mitsias P, Talati S, Tanne D. Agreement and variability in the interpretation of early CT changes in stroke patients qualifying for intravenous rtPA therapy. Stroke. 1999 Aug; 30(8):1528-33.
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Kwatkowski TG, Libman RB, Frankel M, Tilley BC, Morgenstern LB, Lu M, Broderick JP, Lewandowski CA, Marler JR, Levine SR, Brott T. Effects of tissue plasminogen activator for acute ischemic stroke at one year. N Engl J Med. 1999 Jun 10; 340(23):1781-1787.
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Kothari RU, Pancioli A, Liu T, Brott T, Broderick J. Cincinnati Prehospital Stroke Scale: reproducibility and validity. Ann Emerg Med. 1999 Apr; 33(4):373-8.
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Wagner KR, Xi G, Hua Y, Zuccarello M, de Courten-Myers GM, Broderick JP, Brott TG. Ultra-early clot aspiration after lysis with tissue plasminogen activator in a porcine model of intracerebral hemorrhage: edema reduction and blood-brain barrier protection. J Neurosurg. 1999 Mar; 90(3):491-8.
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Hacke W, Brott T, Caplan L, Meier D, Fieschi C, von Kummer R, Donnan G, Heiss WD, Wahlgren NG, Spranger M, Boysen G, Marler JR. Thrombolysis in acute ischemic stroke: controlled trials and clinical experience. Neurology. 1999; 53(7 Suppl 4):S3-14.
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Kothari R, Jauch E, Broderick J, Brott T, Sauerbeck L, Khoury J, Liu T. Acute stroke: Delays to presentation and emergency department evaluation. Annals of Emergency Medicine. 1999; 33(1):3-8.
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Woo D, Gebel J, Miller R, Kothari R, Brott T, Khoury J, Salisbury S, Shukla R, Pancioli A, Broderick J. Incidence rates of first-ever ischemic stroke subtypes among blacks: a population-based study. Stroke. 1999; 30:2517-22.
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Xi G, Wagner KR, Keep RF, Hua Y, de Courten-Myers GM, Broderick JP, Brott TG, Hoff JT, Muizelaar JP. Role of blood clot formation on early edema development after experimental intracerebral hemorrhage. Stroke. 1998 Dec; 29(12):2580-6.
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Brott T, Lu M, Kothari R, Fagan SC, Frankel M, Grotta JC, Broderick J, Kwiatkowski T, Lewandowski C, Haley EC, Marler JR, Tilley BC. Hypertension and its treatment in the NINDS rt-PA Stroke Trial. Stroke. 1998 Aug; 29(8):1504-9.
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Pancioli AM, Broderick J, Kothari R, Brott T, Tuchfarber A, Miller R, Khoury J, Jauch E. Public perception of stroke warning signs and knowledge of potential risk factors. JAMA. 1998 Apr 22-29; 279(16):1288-92.
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Fagan SC, Morgenstern LB, Petitta A, Ward RE, Tilley BC, Marler JR, Levine SR, Broderick JP, Kwiatkowski TG, Frankel M, Brott TG, Walker MD. Cost-effectiveness of tissue plasminogen activator for acute ischemic stroke. NINDS rt-PA Stroke Study Group. Neurology. 1998 Apr; 50(4):883-90.
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Biller J, Feinberg WM, Castaldo JE, Whittemore AD, Harbaugh RE, Dempsey RJ, Caplan LR, Kresowik TF, Matchar DB, Toole JF, Easton JD, Adams HP Jr, Brass LM, Hobson RW 2nd, Brott TG, Sternau L. Guidelines for carotid endarterectomy: a statement for healthcare professionals from a Special Writing Group of the Stroke Council, American Heart Association. Circulation. 1998 Feb 10; 97(5):501-9.
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Broderick J, Brott T, Kothari R, Miller R, Khoury J, Pancioli A, Gebel J, Mills D, Minneci L, Shukla R. The Greater Cincinnati/Northern Kentucky Stroke Study: preliminary first-ever and total incidence rates of stroke among blacks. Stroke. 1998 Feb; 29(2):415-21.
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Tilley BC, Lyden PD, Brott TG, Lu M, Levine SR, Welch KM. Total quality improvement method for reduction of delays between emergency department admission and treatment of acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Arch Neurol. 1997 Dec; 54(12):1466-74.
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Kothari R, Sauerbeck L, Jauch E, Broderick J, Brott T, Khoury J, Liu T. Patients' awareness of stroke signs, symptoms, and risk factors. Stroke. 1997 Oct; 28(10):1871-5.
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Kothari R, Hall K, Brott T, Broderick J. Early stroke recognition: developing an out-of-hospital NIH Stroke Scale. Acad Emerg Med. 1997 Oct; 4(10):986-90.
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Lower EE, Broderick JP, Brott TG, Baughman RP. Diagnosis and management of neurological sarcoidosis. Arch Intern Med. 1997 Sep 8; 157(16):1864-8.
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Pancioli A, Brott T, Donaldson V, Miller R. Asymmetric angioneurotic edema associated with thrombolysis for acute stroke. Ann Emerg Med. 1997 Aug; 30(2):227-9.
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Lyden PD, Grotta JC, Levine SR, Marler JR, Frankel MR, Brott TG. Intravenous thrombolysis for acute stroke. Neurology. 1997 Jul; 49(1):14-20.
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Brott T, Kothari R. Pre-hospital management of stroke patients. Cerebrovasc Dis. 1997; 7(Suppl 3):2-4.
Brott T, Broderick J, Kothari R, Barsan W, Tomsick T, Sauerbeck L, Spilker J, Duldner J, Khoury J. Early hemorrhage growth in patients with intracerebral hemorrhage. Stroke. 1997 Jan; 28(1):1-5.
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Biller J, Feinberg WM, Castaldo JE, Whittemore AD, Harbaugh RE, Dempsey RJ, Caplan LR, Kresowik TF, Matchar DB, Toole JF, Easton JD, Adams HP Jr, Brass LM, Hobson RW, Brott TG, Sternau L. Guidelines for carotid endarterectomy: a statement of healthcare professionals from a special writing group of the stroke council, American Heart Association and the American Academy of Neurology. Stroke. 1997; 29(2):554-62.
McDowell FH, Brott TG, Goldstein M, Grotta JC, Heros RC, Latchaw RE, Robertson JT, Sherman DG, Starkman S, Toole JF. Stroke: the first hours, emergency evaluation and treatment. Stroke Clinical Updates, Special Edition. National Stroke Association:. 1997; 0: 0.
Brott T. Thrombolysis for stroke. Arch Neurol. 1996 Dec; 53(12):1305-6.
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Kothari R, Pancioli A, Brott T, Broderick J. Thrombolytic therapy for cerebral infarction. Acad Emerg Med. 1996 Sep; 3(9):881-92.
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Adams HP Jr, Brott TG, Furlan AJ, Gomez CR, Grotta J, Helgason CM, Kwiatkowski T, Lyden PD, Marler JR, Torner J, Feinberg W, Mayberg M, Thies W. Guidelines for Thrombolytic Therapy for Acute Stroke: a Supplement to the Guidelines for the Management of Patients with Acute Ischemic Stroke. A statement for healthcare professionals from a Special Writing Group of the Stroke Council, American Heart Association. Stroke. 1996 Sep; 27(9):1711-8.
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Kothari RU, Brott T, Broderick JP, Barsan WG, Sauerbeck LR, Zuccarello M, Khoury J. The ABCs of measuring intracerebral hemorrhage volumes. Stroke. 1996 Aug; 27(8):1304-5.
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Wagner KR, Xi G, Hua Y, Kleinholz M, de Courten-Myers GM, Myers RE, Broderick JP, Brott TG. Lobar intracerebral hemorrhage model in pigs: rapid edema development in perihematomal white matter. Stroke. 1996 Mar; 27(3):490-7.
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Tomsick T, Brott T, Barsan W, Broderick J, Haley EC, Spilker J, Khoury J. Prognostic value of the hyperdense middle cerebral artery sign and stroke scale score before ultraearly thrombolytic therapy. AJNR Am J Neuroradiol. 1996 Jan; 17(1):79-85.
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Shuren JE, Brott TG, Schefft BK, Houston W. Preserved color imagery in an achromatopsic. Neuropsychologia. 1996; 34(6):485-489.
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The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med Stroke Study Group. 1995 Dec 14; 333(24):1581-7.
Kothari R, Barsan W, Brott T, Broderick J, Ashbrock S. Frequency and accuracy of prehospital diagnosis of acute stroke. Stroke. 1995 Jun; 26(6):937-41.
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Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. Endarterectomy for asymptomatic carotid artery stenosis. JAMA. 1995 May 10; 273(18):1421-8.
Loncaric S, Dhawan AP, Broderick J, Brott T. 3-D image analysis of intra-cerebral brain hemorrhage from digitized CT films. Comput Methods Programs Biomed. 1995 Apr; 46(3):207-16.
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Tomsick TA, Ernst RJ, Tew JM, Brott TG, Breneman JC. Adult choroidal vein of Galen malformation. AJNR Am J Neuroradiol. 1995 Apr; 16(4 Suppl):861-5.
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Broderick JP, Hagen T, Brott T, Tomsick T. Hyperglycemia and hemorrhagic transformation of cerebral infarcts. Stroke. 1995 Mar; 26(3):484-7.
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Moore WS, Barnett HJ, Beebe HG, Bernstein EF, Brener BJ, Brott T, Caplan LR, Day A, Goldstone J, Hobson RW 2nd. Guidelines for carotid endarterectomy. A multidisciplinary consensus statement from the Ad Hoc Committee, American Heart Association. Circulation. 1995 Jan 15; 91(2):566-79.
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Moore WS, Barnett HJ, Beebe HG, Bernstein EF, Brener BJ, Brott T, Caplan LR, Day A, Goldstone J, Hobson RW 2nd. Guidelines for carotid endarterectomy. A multidisciplinary consensus statement from the ad hoc Committee, American Heart Association. Stroke. 1995 Jan; 26(1):188-201.
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Lyden P, Brott T, Tilley B, Welch KM, Mascha EJ, Levine S, Haley EC, Grotta J, Marler J. Improved reliability of the NIH Stroke Scale using video training. NINDS TPA Stroke Study Group. Stroke. 1994 Nov; 25(11):2220-6.
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Barsan WG, Brott TG, Broderick JP, Haley EC Jr, Levy DE, Marler JR. Urgent therapy for acute stroke. Effects of a stroke trial on untreated patients. Stroke. 1994 Nov; 25(11):2132-7.
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Adams HP Jr, Brott TG, Crowell RM, Furlan AJ, Gomez CR, Grotta J, Helgason CM, Marler JR, Woolson RF, Zivin JA. Guidelines for the management of patients with acute ischemic stroke. A statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association. Stroke. 1994 Sep; 25(9):1901-14.
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Broderick JP, Brott TG, Duldner JE, Tomsick T, Leach A. Initial and recurrent bleeding are the major causes of death following subarachnoid hemorrhage. Stroke. 1994 Jul; 25(7):1342-7.
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Brott T, Tomsick T, Feinberg W, Johnson C, Biller J, Broderick J, Kelly M, Frey J, Schwartz S, Blum C. Baseline silent cerebral infarction in the Asymptomatic Carotid Atherosclerosis Study. Stroke. 1994 Jun; 25(6):1122-9.
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Broderick J, Brott T, Tomsick T, Tew J, Duldner J, Huster G. Management of intracerebral hemorrhage in a large metropolitan population. Neurosurgery. 1994 May; 34(5):882-7; discussion 887.
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Brott T, Broderick J, Kothari R. Thrombolytic therapy for stroke. Curr Opin Neurol. 1994 Feb; 7(1):25-35.
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Levy DE, Brott TG, Haley EC Jr, Marler JR, Sheppard GL, Barsan W, Broderick JP. Factors related to intracranial hematoma formation in patients receiving tissue-type plasminogen activator for acute ischemic stroke. Stroke. 1994 Feb; 25(2):291-7.
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Brott T. Silent cerebral infarction/lacunes. Journal of Stroke and Cerebrovascular Diseases. 1994; 4:S44-S46.
Barsan WG, Brott TG, Broderick JP, Haley EC, Levy DE, Marler JR. Time of hospital presentation in patients with acute stroke. Arch Intern Med. 1993 Nov 22; 153(22):2558-61.
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Broderick J, Brott T, Barsan W, Haley EC, Levy D, Marler J, Sheppard G, Blum C. Blood pressure during the first minutes of focal cerebral ischemia. Ann Emerg Med. 1993 Sep; 22(9):1438-43.
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Broderick J, Talbot GT, Prenger E, Leach A, Brott T. Stroke in children within a major metropolitan area: the surprising importance of intracerebral hemorrhage. J Child Neurol. 1993 Jul; 8(3):250-5.
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Haley EC Jr, Brott TG, Sheppard GL, Barsan W, Broderick J, Marler JR, Kongable GL, Spilker J, Massey S, Hansen CA. Pilot randomized trial of tissue plasminogen activator in acute ischemic stroke. The TPA Bridging Study Group. Stroke. 1993 Jul; 24(7):1000-4.
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Broderick JP, Brott TG, Duldner JE, Tomsick T, Huster G. Volume of intracerebral hemorrhage. A powerful and easy-to-use predictor of 30-day mortality. Stroke. 1993 Jul; 24(7):987-93.
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Broderick JP, Brott T, Tomsick T, Miller R, Huster G. Intracerebral hemorrhage more than twice as common as subarachnoid hemorrhage. J Neurosurg. 1993 Feb; 78(2):188-91.
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Brott T, Broderick JP. Intracerebral hemorrhage. Heart Disease & Stroke. 1993 Jan-Feb; 2(1):59-63.
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McDowell FH, Brott T, Goldstein M, Grotta J, Heros R, Latchaw R, Robertson J, Sherman D, Starkman S, Toole J. The emergency treatment of stroke: the first six hours. Journal of Stroke and Cerebrovascular Diseases. 1993; 3:133-144.
Broderick J, Brott T, Tomsick T, Leach A. Lobar hemorrhage in the elderly. The undiminishing importance of hypertension. Stroke. 1993; 24(1):49-51.
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Adams HP, Brott T, Crowell R. Adult basic life support - Stroke. Health Care Provider's Manual for Basic Life Support and Textbook of Advanced Life Support Stroke. 1993.
Brott T. Utility of the National Institutes of Health stroke scale. Cerebrovasc Dis. 1992 Jul-Aug; 2(4):241-2.
Haley EC Jr, Levy DE, Brott TG, Sheppard GL, Wong MC, Kongable GL, Torner JC, Marler JR. Urgent therapy for stroke. Part II. Pilot study of tissue plasminogen activator administered 91-180 minutes from onset. Stroke. 1992 May; 23(5):641-5.
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Brott TG, Haley EC Jr, Levy DE, Barsan W, Broderick J, Sheppard GL, Spilker J, Kongable GL, Massey S, Reed R. Urgent therapy for stroke. Part I. Pilot study of tissue plasminogen activator administered within 90 minutes. Stroke. 1992 May; 23(5):632-40.
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Broderick JP, Brott T, Tomsick T, Huster G, Miller R. The risk of subarachnoid and intracerebral hemorrhages in blacks as compared with whites. N Engl J Med. 1992 Mar 12; 326(11):733-6.
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Brott T. Thrombolytic therapy. Neurol Clin. 1992 Feb; 10(1):219-32.
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Tomsick T, Brott T, Barsan W, Broderick J, Haley EC, Spilker J. Thrombus localization with emergency cerebral CT. AJNR Am J Neuroradiol. 1992 Jan-Feb; 13(1):257-63.
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Levine SR, Brott TG. Thrombolytic therapy in cerebrovascular disorders. Prog Cardiovasc Dis. 1992 Jan-Feb; 34(4):235-62.
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Adams HP, Brott T, Crowell R. Emergency cardiac care committee and subcommittees, American Heart Association. JAMA. 1992; 268:2242-2244.
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Brott T, Stump D. Overview of hemostasis and thrombosis. Semin Neurol. 1991 Dec; 11(4):305-13.
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North American Symptomatic Carotid Endarterectomy Trial Collaborators. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N Engl J Med. 1991 Aug 15; 325(7):445-53.
Brott T. Prevention and management of medical complications of the hospitalized elderly stroke patient. Clin Geriatr Med. 1991 Aug; 7(3):475-82.
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Brott T. Thrombolytic therapy for stroke. Cerebrovascular & Brain Metabolism Reviews. 1991 Summer; 3(2):91-113.
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Brott T. Neurological complications of clotting disorders. Seminars in Neurology 11. 1991; 0: 0.
Tomsick TA, Brott TG, Chambers AA, Fox AJ, Gaskill MF, Lukin RR, Pleatman CW, Wiot JG, Bourekas E. Hyperdense middle cerebral artery sign on CT: efficacy in detecting middle cerebral artery thrombosis. AJNR Am J Neuroradiol. 1990 May; 11(3):473-7.
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Olinger CP, Adams HP Jr, Brott TG, Biller J, Barsan WG, Toffol GJ, Eberle RW, Marler JR. High-dose intravenous naloxone for the treatment of acute ischemic stroke. Stroke. 1990 May; 21(5):721-5.
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Broderick JP, Brott TG, Tomsick T, Barsan W, Spilker J. Ultra-early evaluation of intracerebral hemorrhage. J Neurosurg. 1990 Feb; 72(2):195-9.
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Barsan W, Brott T. Treatment of acute ischemic stroke. Stroke, Clinical Updates. 1990; 1:1-4.
Barsan WG, Brott TG, Olinger CP, Marler JR. Early treatment for acute ischemic stroke. Ann Intern Med. 1989 Sep 15; 111(6):449-51.
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Barsan WG, Olinger CP, Adams HP Jr, Brott TG, Eberle R, Biller J, Biros M, Marler J. Use of high dose naloxone in acute stroke: possible side-effects. Crit Care Med. 1989 Aug; 17(8):762-7.
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Brott T, Marler JR, Olinger CP, Adams HP Jr, Tomsick T, Barsan WG, Biller J, Eberle R, Hertzberg V, Walker M. Measurements of acute cerebral infarction: lesion size by computed tomography. Stroke. 1989 Jul; 20(7):871-5.
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Brott T, Adams HP Jr, Olinger CP, Marler JR, Barsan WG, Biller J, Spilker J, Holleran R, Eberle R, Hertzberg V. Measurements of acute cerebral infarction: a clinical examination scale. Stroke. 1989 Jul; 20(7):864-70.
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Brott T, Reed RL. Intensive care for acute stroke in the community hospital setting. The first 24 hours. Stroke. 1989 May; 20(5):694-7.
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Bienenfeld D, Brott T. Capgras' syndrome following minor head trauma. J Clin Psychiatry. 1989 Feb; 50(2):68-9.
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Tomsick TA, Brott TG, Olinger CP, Barsan W, Spilker J, Eberle R, Adams H. Hyperdense middle cerebral artery: incidence and quantitative significance. Neuroradiology. 1989; 31(4):312-5.
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Timerding BL, Barsan WG, Hedges JR, Brott TG, VanLigten PF, Spilker JA, Olinger CP. Stroke patient evaluation in the emergency department before pharmacologic therapy. Am J Emerg Med. 1989 Jan; 7(1):11-5.
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Olinger CP, Brott TG, Barsan WG, Hedges JR, Glas-Greenwalt P, Pollak VE, Spilker J, Eberle R. Use of ancrod in acute or progressing ischemic cerebral infarction. Ann Emerg Med. 1988 Nov; 17(11):1208-9.
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Brott T, Haley EC, Levy DE, Barsan WG, Reed RL, Olinger CP, Marler JR. The investigational use of tPA for stroke. Ann Emerg Med. 1988 Nov; 17(11):1202-5.
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Barsan WG, Brott TG, Olinger CP, Adams HP Jr, Haley EC Jr, Levy DE. Identification and entry of the patient with acute cerebral infarction. Ann Emerg Med. 1988 Nov; 17(11):1192-5.
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Adams HP Jr, Olinger CP, Marler JR, Biller J, Brott TG, Barsan WG, Banwart K. Comparison of admission serum glucose concentration with neurologic outcome in acute cerebral infarction. A study in patients given naloxone. Stroke. 1988 Apr; 19(4):455-8.
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Brott T, Mandybur TI. Case-control study of clinical outcome after aneurysmal subarachnoid hemorrhage. Neurosurgery. 1986 Dec; 19(6):891-5.
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Brott T, Thalinger K, Hertzberg V. Hypertension as a risk factor for spontaneous intracerebral hemorrhage. Stroke. 1986 Nov-Dec; 17(6):1078-83.
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Kempczinski RF, Brott TG, Labutta RJ. The influence of surgical specialty and caseload on the results of carotid endarterectomy. J Vasc Surg. 1986 Jun; 3(6):911-6.
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Brott TG, Labutta RJ, Kempczinski RF. Changing patterns in the practice of carotid endarterectomy in a large metropolitan area. JAMA. 1986 May 16; 255(19):2609-12.
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Adams HP Jr, Olinger CP, Barsan WG, Butler MJ, Graff-Radford NR, Brott TG, Biller J, Damasio H, Tomsick T, Goldberg M. A dose-escalation study of large doses of naloxone for treatment of patients with acute cerebral ischemia. Stroke. 1986 May-Jun; 17 (3):404-9
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Brott TG, Gelfand MJ, Williams CC, Spilker JA, Hertzberg VS. Frequency and patterns of abnormality detected by iodine-123 amine emission CT after cerebral infarction. Radiology. 1986 Mar; 158(3):729-34.
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Brott T, Thalinger K. The practice of carotid endarterectomy in a large metropolitan area. Stroke. 1984 Nov-Dec; 15(6):950-5.
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Brott T, Leviton A. Violence. Headache. 1976 Nov; 16(5):203-9.
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Thomas G. Brott, M.D.

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