Publications

1. Rajalingamgari P, Khatua B, Summers MJ, Kostenko S, Chang YH, Elmallahy M, Anand A, Narayana Pillai A, Morsy M, Trivedi S, McFayden B, Jahangir S, Snozek CL, Singh VP. Prospective observational study and mechanistic evidence showing lipolysis of circulating triglycerides worsens hypertriglyceridemic acute pancreatitis. J Clin Invest. 2024 Nov 7 Epub 2024 Nov 07
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2. Karri J, Sivanesan E, Gulati A, Singh V, Sheen S, Yalamuru B, Wang EJ, Javed S, Chung M, Sohini R, Hussain N, D'Souza RS. Peripheral Nerve Stimulation for Pain Management: A Survey of Clinical Practice Patterns. Neuromodulation. 2024 Oct 11 [Epub ahead of print]
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3. Aldhaleei WA, Bilgin C, Biswas A, D'Oria M, Faghani S, Ghozy S, Hassan A, Jiang H, Kim MS, Kumar A, Lee WC, Mahmoudi E, Mohamed AI, Mohamed MFH, Nguyen PT, Nugen F, Patel J, Patel SK, Philip AK, Phillips MR, Sharma V, Singh S, Vahdati S, Xiao H, Yang D, Yu C, Zhang J, GBD 2021 Tobacco Forecasting Collaborators. Forecasting the effects of smoking prevalence scenarios on years of life lost and life expectancy from 2022 to 2050: a systematic analysis for the Global Burden of Disease Study 2021. Lancet Public Health. 2024 Oct; 9 (10):e729-e744
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4. Summers M, Russell B, Rajalingamgari P, Morsy M, Jahangir S, Gold A, Gades N, Wasif N, Singh VP. A safe method for rapid therapeutic pancreatic cooling. iScience. 2024 Sep 20; 27 (9):110790 Epub 2024 Aug 30
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5. Jahangir S, Khatua B, Smichi N, Rajalingamgari P, Narayana Pillai A, Summers MJ, McFayden B, Kostenko S, Gades NM, Singh VP. Buprenorphine affects the initiation and severity of interleukin-induced acute pancreatitis in mice. Am J Physiol Gastrointest Liver Physiol. 2024 Jul 1; 327 (1):G16-G24 Epub 2024 Apr 23
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6. El Kurdi B, Imam Z, Abonofal A, Babar S, Shah P, Pannala R, Papachristou G, Echavarria J, Pisipati S, Jahangir S, Rajalingamgari P, Chang YH, Singh VP. NSAIDs do not reduce severity among post-ERCP pancreatitis patients. Pancreatology. 2024 Feb; 24 (1):14-23 Epub 2023 Nov 02
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7. Singh V, Jolissaint JE, Kohler JG, Goh MH, Chen AF, Bedard NA, Springer BD, Schwarzkopf R. Precision or Pitfall? Evaluating the Accuracy of ICD-10 Coding for Cemented Total Hip Arthroplasty: A Multicenter Study. J Bone Joint Surg Am. 2024 Jan 3; 106 (1):56-61 Epub 2023 Nov 16
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8. Kostenko S, Khatua B, Trivedi S, Pillai AN, McFayden B, Morsy M, Rajalingamgari P, Sharma V, Noel P, Patel K, El-Kurdi B, Borges da Silva H, Chen X, Chandan V, Navina S, Vela S, Cartin-Ceba R, Snozek C, Singh VP. Amphipathic Liponecrosis Impairs Bacterial Clearance and Causes Infection During Sterile Inflammation. Gastroenterology. 2023 Oct; 165 (4):999-1015 Epub 2023 May 30
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9. Phillips AE, Wilson AS, Greer PJ, Hinton A, Culp S, Paragomi P, Pothoulakis I, Singh V, Lee PJ, Lahooti I, Whitcomb DC, Papachristou GI. Relationship of circulating levels of long-chain fatty acids to persistent organ failure in acute pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2023 Sep 1; 325 (3):G279-G285 Epub 2023 July 18
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10. Kiss L, Fur G, Pisipati S, Rajalingamgari P, Ewald N, Singh V, Rakonczay Z Jr. Mechanisms linking hypertriglyceridemia to acute pancreatitis. Acta Physiol (Oxf). 2023 Mar; 237 (3):e13916 Epub 2023 Jan 13
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11. Ahmed M, Wright K, Singh S, Ghozy S, Abbas AS, Brown R, Rhee D, Schuelke MR, Kloeber JA, Owen RL, Roth AS, Jay LP, Wyatt KD, Galardy PJ, Ahmed A, Global Health Research Group on Children’s Non-Communicable Diseases Collaborative. Twelve-month observational study of children with cancer in 41 countries during the COVID-19 pandemic. BMJ Glob Health. 2022 Oct; 7 (10)
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12. Smith RJ, Lachner C, Singh VP, Trivedi S, Khatua B, Cartin-Ceba R. Cytokine profiles in intensive care unit delirium. Acute Crit Care. 2022 Aug; 37 (3):415-428 Epub 2022 June 20
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13. Smith RJ, Rabinstein AA, Cartin-Ceba R, Singh VP, Lachner C, Khatua B, Trivedi S, Gajic O. Chemokines in ICU Delirium: An Exploratory Study. Crit Care Explor. 2022 Jul; 4 (7):e0729 Epub 2022 July 05
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14. Chaffin H, Trivedi S, Singh VP. Impact of abdominal imaging on the diagnosis of acute pancreatitis in patients with painless lipase elevation. Pancreatology. 2022 Jun; 22 (5):547-552 Epub 2022 Apr 29
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15. Cartin-Ceba R, Khatua B, El-Kurdi B, Trivedi S, Kostenko S, Imam Z, Smith R, Snozek C, Navina S, Sharma V, McFayden B, Ionescu F, Stolow E, Keiser S, Tejani A, Harrington A, Acosta P, Kuwelker S, Echavarria J, Nair GB, Bataineh A, Singh VP. Evidence showing lipotoxicity worsens outcomes in covid-19 patients and insights about the underlying mechanisms. iScience. 2022 May 20; 25 (5):104322 Epub 2022 Apr 27
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16. Smith RJ, Lachner C, Singh VP, Cartin-Ceba R. Intensive care unit delirium in patients with severe COVID-19: A prospective observational cohort study. Int J Crit Illn Inj Sci. 2022 Apr-Jun; 12 (2):61-69 Epub 2022 June 24
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17. Katayama M, Gades NM, Singh VP, Devick KL, Zarbatany D, Vaitkus VV, Belohlavek DL, Fortuin FD, Belohlavek M. Doppler-Guided Acoustically Active Injection Catheter: Transendocardial Delivery Assessed by an Efficacy Testing Animal Model. J Ultrasound Med. 2022 Mar; 41 (3):749-762 Epub 2021 May 03
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18. Ostaszewski M, Niarakis A, Mazein A, Kuperstein I, Phair R, Orta-Resendiz A, Singh V, Aghamiri SS, Acencio ML, Glaab E, Ruepp A, Fobo G, Montrone C, Brauner B, Frishman G, Monraz Gomez LC, Somers J, Hoch M, Kumar Gupta S, Scheel J, Borlinghaus H, Czauderna T, Schreiber F, Montagud A, Ponce de Leon M, Funahashi A, Hiki Y, Hiroi N, Yamada TG, Drager A, Renz A, Naveez M, Bocskei Z, Messina F, Bornigen D, Fergusson L, Conti M, Rameil M, Nakonecnij V, Vanhoefer J, Schmiester L, Wang M, Ackerman EE, Shoemaker JE, Zucker J, Oxford K, Teuton J, Kocakaya E, Summak GY, Hanspers K, Kutmon M, Coort S, Eijssen L, Ehrhart F, Rex DAB, Slenter D, Martens M, Pham N, Haw R, Jassal B, Matthews L, Orlic-Milacic M, Senff-Ribeiro A, Rothfels K, Shamovsky V, Stephan R, Sevilla C, Varusai T, Ravel JM, Fraser R, Ortseifen V, Marchesi S, Gawron P, Smula E, Heirendt L, Satagopam V, Wu G, Riutta A, Golebiewski M, Owen S, Goble C, Hu X, Overall RW, Maier D, Bauch A, Gyori BM, Bachman JA, Vega C, Groues V, Vazquez M, Porras P, Licata L, Iannuccelli M, Sacco F, Nesterova A, Yuryev A, de Waard A, Turei D, Luna A, Babur O, Soliman S, Valdeolivas A, Esteban-Medina M, Pena-Chilet M, Rian K, Helikar T, Puniya BL, Modos D, Treveil A, Olbei M, De Meulder B, Ballereau S, Dugourd A, Naldi A, Noel V, Calzone L, Sander C, Demir E, Korcsmaros T, Freeman TC, Auge F, Beckmann JS, Hasenauer J, Wolkenhauer O, Willighagen EL, Pico AR, Evelo CT, Gillespie ME, Stein LD, Hermjakob H, D'Eustachio P, Saez-Rodriguez J, Dopazo J, Valencia A, Kitano H, Barillot E, Auffray C, Balling R, Schneider R, COVID-19 Disease Map Community. COVID-19 Disease Map, a computational knowledge repository of virus-host interaction mechanisms. Mol Syst Biol. 2021 Dec; 17 (12):e10851
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19. Vela S, Guerra A, Farrell G, Trivedi S, Chaffin H, Rood C, Singh R, Kostenko S, Chang YH, Snozek C, Patel K, Khatua B, Singh VP. Pathophysiology and Biomarker Potential of Fatty Acid Ethyl Ester Elevation During Alcoholic Pancreatitis. Gastroenterology. 2021 Nov; 161 (5):1513-1525 Epub 2021 July 23
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20. Abdul-Muhsin H, De Lucia N, Singh V, Faraj K, Rose K, Cha S, Zhang N, Judge N, Navaratnam A, Tyson M, Ho T, Jacobsohn K, Castle E. Outcome prediction following radical nephroureterectomy for upper tract urothelial carcinoma. Urol Oncol. 2021 Feb; 39(2):133.e9-133.e16. Epub 2020 Oct 15.
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21. Aman MM, Mahmoud A, Deer T, Sayed D, Hagedorn JM, Brogan SE, Singh V, Gulati A, Strand N, Weisbein J, Goree JH, Xing F, Valimahomed A, Pak DJ, El Helou A, Ghosh P, Shah K, Patel V, Escobar A, Schmidt K, Shah J, Varshney V, Rosenberg W, Narang S. The American Society of Pain and Neuroscience (ASPN) Best Practices and Guidelines for the Interventional Management of Cancer-Associated Pain. J Pain Res. 2021; 14:2139-2164 Epub 2021 July 16
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22. Carll WC, Rady MY, Salomao MA, Patel B, Singh VP, Sen A. Cytomegalovirus haemorrhagic enterocolitis associated with severe infection with COVID-19. BMJ Open Gastroenterol. 2021 Jan; 8 (1)
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23. Khatua B, El-Kurdi B, Patel K, Rood C, Noel P, Crowell M, Yaron JR, Kostenko S, Guerra A, Faigel DO, Lowe M, Singh VP. Adipose saturation reduces lipotoxic systemic inflammation and explains the obesity paradox. Sci Adv. 2021 Jan; 7 (5) Epub 2021 Jan 29
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24. Kostenko S, Folmes C, Chang YH, Pannala R, El-Kurdi B, Khatua B, Rood C, Snozek C, Cartin-Ceba R, Singh VP, Lipotoxicity in COVID-19 Study Group. Mortality From Coronavirus Disease 2019 Increases With Unsaturated Fat and May Be Reduced by Early Calcium and Albumin Supplementation. Gastroenterology. 2020 Sep; 159 (3):1015-1018.e4 Epub 2020 May 27
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25. Faraj KS, Judge NZ, Rose KM, Eversman S, Richards J, Blodgett G, Singh V, DeLucia NM, Humphreys MR, Castle EP, Tyson MD 2nd. How the Beneficial Effects of Alvimopan Differ With Surgical Approach for Radical Cystectomy. Urology. 2020 Jun; 140:107-114 Epub 2020 Feb 27
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26. de Oliveira C, Khatua B, El-Kurdi B, Patel K, Mishra V, Navina S, Grim BJ, Gupta S, Belohlavek M, Cherry B, Yarger J, Green MD, Singh VP. Thermodynamic interference with bile acid demicelleization reduces systemic entry and injury during cholestasis. Sci Rep. 2020 May 21; 10 (1):8462
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27. Zadori N, Gede N, Antal J, Szentesi A, Alizadeh H, Vincze A, Izbeki F, Papp M, Czako L, Varga M, de-Madaria E, Petersen OH, Singh VP, Mayerle J, Faluhelyi N, Miseta A, Reiber I, Hegyi P. EarLy Elimination of Fatty Acids iN hypertriglyceridemia-induced acuTe pancreatitis (ELEFANT trial): Protocol of an open-label, multicenter, adaptive randomized clinical trial. Pancreatology. 2020 Apr; 20 (3):369-376 Epub 2019 Dec 30
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28. de Oliveira C, Khatua B, Noel P, Kostenko S, Bag A, Balakrishnan B, Patel KS, Guerra AA, Martinez MN, Trivedi S, McCullough A, Lam-Himlin DM, Navina S, Faigel DO, Fukami N, Pannala R, Phillips AE, Papachristou GI, Kershaw EE, Lowe ME, Singh VP. Pancreatic triglyceride lipase mediates lipotoxic systemic inflammation. J Clin Invest. 2020 Apr 1; 130 (4):1931-1947
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29. Khatua B, Yaron JR, El-Kurdi B, Kostenko S, Papachristou GI, Singh VP. Ringer's Lactate Prevents Early Organ Failure by Providing Extracellular Calcium. J Clin Med. 2020 Jan 18; 9 (1)
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30. Sternby H, Mahle M, Linder N, Erichson-Kirst L, Verdonk RC, Dimova A, Ignatavicius P, Ilzarbe L, Koiva P, Penttila A, Regner S, Bollen TL, Brill R, Stangl F, Wohlgemuth WA, Singh V, Busse H, Michl P, Beer S, Rosendahl J. Mean muscle attenuation correlates with severe acute pancreatitis unlike visceral adipose tissue and subcutaneous adipose tissue. United European Gastroenterol J. 2019 Dec; 7 (10):1312-1320 Epub 2019 Oct 09
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31. Navaratnam A, Faraj K, Rose K, Abdul-Muhsin H, Singh V, Schwartz A, Beauchamp C, Castle EP. Robot Assisted Cystectomy With Holmium Laser Debridement for Osteomyelitis of the Pubic Symphysis With Urinary Fistula. Urology. 2019 Dec; 134:124-134 Epub 2019 Sept 19
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32. El Kurdi B, Babar S, El Iskandarani M, Bataineh A, Lerch MM, Young M, Singh VP. Factors That Affect Prevalence of Small Intestinal Bacterial Overgrowth in Chronic Pancreatitis: A Systematic Review, Meta-Analysis, and Meta-Regression. Clin Transl Gastroenterol. 2019 Sep; 10 (9):e00072
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33. Khatua B, Trivedi RN, Noel P, Patel K, Singh R, de Oliveira C, Trivedi S, Mishra V, Lowe M, Singh VP. Carboxyl Ester Lipase May Not Mediate Lipotoxic Injury during Severe Acute Pancreatitis. Am J Pathol. 2019 Jun; 189 (6):1226-1240 Epub 2019 Apr 05
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34. Garg PK, Singh VP. Organ Failure Due to Systemic Injury in Acute Pancreatitis. Gastroenterology. 2019 May; 156 (7):2008-2023 Epub 2019 Feb 12
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35. de Oliveira C, Khatua B, Bag A, El-Kurdi B, Patel K, Mishra V, Navina S, Singh VP. Multimodal Transgastric Local Pancreatic Hypothermia Reduces Severity of Acute Pancreatitis in Rats and Increases Survival. Gastroenterology. 2019 Feb; 156 (3):735-747.e10 Epub 2018 Oct 25
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36. Kostenko S, Heu CC, Yaron JR, Singh G, de Oliveira C, Muller WJ, Singh VP. c-Src regulates cargo transit via the Golgi in pancreatic acinar cells. Sci Rep. 2018 Aug 9; 8 (1):11903 Epub 2018 Aug 09
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37. Chiu HS, Somvanshi S, Patel E, Chen TW, Singh VP, Zorman B, Patil SL, Pan Y, Chatterjee SS, Sood AK, Gunaratne PH, Sumazin P, Cancer Genome Atlas Research Network. Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context. Cell Rep. 2018 Apr 3; 23 (1):297-312.e12
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38. Zhou HH, Singh V, Johnson SC, Wahba G, Alzheimer's Disease Neuroimaging Initiative. Statistical tests and identifiability conditions for pooling and analyzing multisite datasets. Proc Natl Acad Sci U S A. 2018 Feb 13; 115 (7):1481-1486 Epub 2018 Jan 31
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39. Majumder S, Philip NA, Takahashi N, Levy MJ, Singh VP, Chari ST. Fatty Pancreas: Should We Be Concerned? Pancreas. 2017 Nov/Dec; 46 (10):1251-1258
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40. Khatua B, El-Kurdi B, Singh VP. Obesity and pancreatitis. Curr Opin Gastroenterol. 2017 Sep; 33 (5):374-382
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41. Easler JJ, de-Madaria E, Nawaz H, Moya-Hoyo N, Koutroumpakis E, Rey-Riveiro M, Singh VP, Acevedo-Piedra NG, Whitcomb DC, Yadav D, Papachristou GI. Patients With Sentinel Acute Pancreatitis of Alcoholic Etiology Are at Risk for Organ Failure and Pancreatic Necrosis: A Dual-Center Experience. Pancreas. 2016 Aug; 45 (7):997-1002
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42. Patel K, Durgampudi C, Noel P, Trivedi RN, de Oliveira C, Singh VP. Fatty Acid Ethyl Esters Are Less Toxic Than Their Parent Fatty Acids Generated during Acute Pancreatitis. Am J Pathol. 2016 Apr; 186 (4):874-84 Epub 2016 Feb 12
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43. de Oliveira C, Patel K, Mishra V, Trivedi RN, Noel P, Singh A, Yaron JR, Singh VP. Characterization and Predictive Value of Near Infrared 2-Deoxyglucose Optical Imaging in Severe Acute Pancreatitis. PLoS One. 2016; 11 (2):e0149073 Epub 2016 Feb 22
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44. Noel P, Patel K, Durgampudi C, Trivedi RN, de Oliveira C, Crowell MD, Pannala R, Lee K, Brand R, Chennat J, Slivka A, Papachristou GI, Khalid A, Whitcomb DC, DeLany JP, Cline RA, Acharya C, Jaligama D, Murad FM, Yadav D, Navina S, Singh VP. Peripancreatic fat necrosis worsens acute pancreatitis independent of pancreatic necrosis via unsaturated fatty acids increased in human pancreatic necrosis collections. Gut. 2016 Jan; 65 (1):100-11 Epub 2014 Dec 10
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45. Nawaz H, Koutroumpakis E, Easler J, Slivka A, Whitcomb DC, Singh VP, Yadav D, Papachristou GI. Elevated serum triglycerides are independently associated with persistent organ failure in acute pancreatitis. Am J Gastroenterol. 2015 Oct; 110 (10):1497-503 Epub 2015 Sept 01
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46. Patel KS, Singh VP. Experimental acute pancreatitis models relevant to lipids and obesity. Pancreapedia: Exocrine Pancreas Knowledge Base. 2015 Sep 9.
    
47. Navina S, Singh VP. Relationship between obesity and pancreatitis. The Pancreapedia: Exocrine Pancreas Knowledge Base. 2015 Jun 13.
    
48. Loverdos I, Swan MC, Shekherdimian S, Al-Rasheed AA, Schneider R, Fish JS, Ngan BY, Adeli K, Lowe ME, Singh VP, Sevilla WM, Langer JC, Gonska T. A case of pancreatitis, panniculitis and polyarthritis syndrome: Elucidating the pathophysiologic mechanisms of a rare condition. J Pediatr Surg Case Rep. 2015 May; 3 (5):223-226
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49. Patel K, Trivedi RN, Durgampudi C, Noel P, Cline RA, DeLany JP, Navina S, Singh VP. Lipolysis of visceral adipocyte triglyceride by pancreatic lipases converts mild acute pancreatitis to severe pancreatitis independent of necrosis and inflammation. Am J Pathol. 2015 Mar; 185 (3):808-19 Epub 2015 Jan 08
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50. Behari J, Li H, Liu S, Stefanovic-Racic M, Alonso L, O'Donnell CP, Shiva S, Singamsetty S, Watanabe Y, Singh VP, Liu Q. beta-catenin links hepatic metabolic zonation with lipid metabolism and diet-induced obesity in mice. Am J Pathol. 2014 Dec; 184(12):3284-98. Epub 2014 Oct 07.
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51. Mishra V, Patel K, Trivedi RN, Noel P, Durgampudi C, Acharya C, Holmes JA, Narla S, Singh VP. Hypothermia slows sequential and parallel steps initiated during caerulein pancreatitis. Pancreatology. 2014 Nov-Dec; 14(6):459-64. Epub 2014 Jul 03.
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52. Acharya C, Navina S, Singh VP. Role of pancreatic fat in the outcomes of pancreatitis. Pancreatology. 2014 Sep-Oct; 14 (5):403-8 Epub 2014 July 01
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53. Navina S, McGrath K, Chennat J, Singh V, Pal T, Zeh H, Krasinskas AM. Adequacy assessment of endoscopic ultrasound-guided, fine-needle aspirations of pancreatic masses for theranostic studies: optimization of current practices is warranted. Arch Pathol Lab Med. 2014 Jul; 138(7):923-8.
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54. Patel KS, Noel P, Singh VP. Potential influence of intravenous lipids on the outcomes of acute pancreatitis. Nutr Clin Pract. 2014 Jun; 29 (3):291-4 Epub 2014 Mar 31
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55. Durgampudi C, Noel P, Patel K, Cline R, Trivedi RN, DeLany JP, Yadav D, Papachristou GI, Lee K, Acharya C, Jaligama D, Navina S, Murad F, Singh VP. Acute lipotoxicity regulates severity of biliary acute pancreatitis without affecting its initiation. Am J Pathol. 2014 Jun; 184 (6):1773-84
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56. Scherer J, Singh VP, Pitchumoni CS, Yadav D. Issues in hypertriglyceridemic pancreatitis: an update. J Clin Gastroenterol. 2014 Mar; 48(3):195-203.
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57. Mahmoud AM, Ding X, Dutta D, Singh VP, Kim K. Detecting hepatic steatosis using ultrasound-induced thermal strain imaging: an ex vivo animal study. Phys Med Biol. 2014 Feb 21; 59(4):881-95. Epub 2014 Feb 03.
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58. Acharya C, Cline RA, Jaligama D, Noel P, Delany JP, Bae K, Furlan A, Baty CJ, Karlsson JM, Rosario BL, Patel K, Mishra V, Dugampudi C, Yadav D, Navina S, Singh VP. Fibrosis reduces severity of acute-on-chronic pancreatitis in humans. Gastroenterology. 2013 Aug; 145 (2):466-75 Epub 2013 May 15
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59. Muili KA, Wang D, Orabi AI, Sarwar S, Luo Y, Javed TA, Eisses JF, Mahmood SM, Jin S, Singh VP, Ananthanaravanan M, Perides G, Williams JA, Molkentin JD, Husain SZ. Bile acids induce pancreatic acinar cell injury and pancreatitis by activating calcineurin. J Biol Chem. 2013 Jan 4; 288 (1):570-80 Epub 2012 Nov 12
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60. Working Group IAP/APA. IAP/APA evidence-based guidelines for the management of acute pancreatitis. Pancreatology. 2013; 13:e1-e15.
    
61. Mishra V, Cline R, Noel P, Karlsson J, Baty CJ, Orlichenko L, Patel K, Trivedi RN, Husain SZ, Acharya C, Durgampudi C, Stolz DB, Navina S, Singh VP. Src Dependent Pancreatic Acinar Injury Can Be Initiated Independent of an Increase in Cytosolic Calcium. PLoS One. 2013; 8(6):e66471. Epub 2013 Jun 18
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62. Whitcomb DC, LaRusch J, Krasinskas AM, Klei L, Smith JP, Brand RE, Neoptolemos JP, Lerch MM, Tector M, Sandhu BS, Guda NM, Orlichenko L, Alkaade S, Amann ST, Anderson MA, Baillie J, Banks PA, Conwell D, Cote GA, Cotton PB, DiSario J, Farrer LA, Forsmark CE, Johnstone M, Gardner TB, Gelrud A, Greenhalf W, Haines JL, Hartman DJ, Hawes RA, Lawrence C, Lewis M, Mayerle J, Mayeux R, Melhem NM, Money ME, Muniraj T, Papachristou GI, Pericak-Vance MA, Romagnuolo J, Schellenberg GD, Sherman S, Simon P, Singh VP, Slivka A, Stolz D, Sutton R, Weiss FU, Wilcox CM, Zarnescu NO, Wisniewski SR, O'Connell MR, Kienholz ML, Roeder K, Barmada MM, Yadav D, Devlin B, Alzheimer's Disease Genetics Consortium. Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. Nat Genet. 2012 Dec; 44 (12):1349-54 Epub 2012 Nov 11
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63. Orlichenko L, Stolz DB, Noel P, Behari J, Liu S, Singh VP. ADP-ribosylation factor 1 protein regulates trypsinogen activation via organellar trafficking of procathepsin B protein and autophagic maturation in acute pancreatitis. J Biol Chem. 2012 Jul 13; 287 (29):24284-93 Epub 2012 May 08
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64. Husain SZ, Orabi AI, Muili KA, Luo Y, Sarwar S, Mahmood SM, Wang D, Choo-Wing R, Singh VP, Parness J, Ananthanaravanan M, Bhandari V, Perides G. Ryanodine receptors contribute to bile acid-induced pathological calcium signaling and pancreatitis in mice. Am J Physiol Gastrointest Liver Physiol. 2012 Jun 15; 302 (12):G1423-33 Epub 2012 Apr 19
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65. Liu S, Yeh TH, Singh VP, Shiva S, Krauland L, Li H, Zhang P, Kharbanda K, Ritov V, Monga SP, Scott DK, Eagon PK, Behari J. beta-catenin is essential for ethanol metabolism and protection against alcohol-mediated liver steatosis in mice. Hepatology. 2012 Mar; 55 (3):931-40
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66. Singh VP. Src: Regulation and function in the exocrine pancreas. The Pancreapedia: Exocrine Pancreas Knowledge Base. 2012.
    
67. Orabi AI, Luo Y, Ahmad MU, Shah AU, Mannan Z, Wang D, Sarwar S, Muili KA, Shugrue C, Kolodecik TR, Singh VP, Lowe ME, Thrower E, Chen J, Husain SZ. IP3 receptor type 2 deficiency is associated with a secretory defect in the pancreatic acinar cell and an accumulation of zymogen granules. PLoS One. 2012; 7 (11):e48465 Epub 2012 Nov 21
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68. Navina S, Acharya C, DeLany JP, Orlichenko LS, Baty CJ, Shiva SS, Durgampudi C, Karlsson JM, Lee K, Bae KT, Furlan A, Behari J, Liu S, McHale T, Nichols L, Papachristou GI, Yadav D, Singh VP. Lipotoxicity causes multisystem organ failure and exacerbates acute pancreatitis in obesity. Sci Transl Med. 2011 Nov 2; 3 (107):107ra110
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69. Yeh TH, Krauland L, Singh V, Zou B, Devaraj P, Stolz DB, Franks J, Monga SP, Sasatomi E, Behari J. Liver-specific beta-catenin knockout mice have bile canalicular abnormalities, bile secretory defect, and intrahepatic cholestasis. Hepatology. 2010 Oct; 52(4):1410-9.
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70. Orlichenko LS, Behari J, Yeh TH, Liu S, Stolz DB, Saluja AK, Singh VP. Transcriptional regulation of CXC-ELR chemokines KC and MIP-2 in mouse pancreatic acini. Am J Physiol Gastrointest Liver Physiol. 2010 Oct; 299 (4):G867-76 Epub 2010 July 29
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71. Singh V, Alexander JA. The evaluation and management of obscure and occult gastrointestinal bleeding. Abdom Imaging. 2009 May-Jun; 34 (3):311-9
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72. Singh VP, Bren GD, Algeciras-Schimnich A, Schnepple D, Navina S, Rizza SA, Dawra RK, Saluja AK, Chari ST, Vege SS, Badley AD. Nelfinavir/ritonavir reduces acinar injury but not inflammation during mouse caerulein pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2009 May; 296 (5):G1040-6 Epub 2009 Mar 12
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73. Singh VP, McNiven MA. Src-mediated cortactin phosphorylation regulates actin localization and injurious blebbing in acinar cells. Mol Biol Cell. 2008 May; 19 (5):2339-47 Epub 2008 Mar 19
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74. Bhagat L, Singh VP, Dawra RK, Saluja AK. Sodium arsenite induces heat shock protein 70 expression and protects against secretagogue-induced trypsinogen and NF-kappaB activation. J Cell Physiol. 2008 Apr; 215 (1):37-46
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75. Singh VP, Bhagat L, Navina S, Sharif R, Dawra RK, Saluja AK. Protease-activated receptor-2 protects against pancreatitis by stimulating exocrine secretion. Gut. 2007 Jul; 56 (7):958-64 Epub 2006 Nov 17
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76. Song AM, Bhagat L, Singh VP, Van Acker GG, Steer ML, Saluja AK. Inhibition of cyclooxygenase-2 ameliorates the severity of pancreatitis and associated lung injury. Am J Physiol Gastrointest Liver Physiol. 2002 Nov; 283 (5):G1166-74
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77. Van Acker GJ, Saluja AK, Bhagat L, Singh VP, Song AM, Steer ML. Cathepsin B inhibition prevents trypsinogen activation and reduces pancreatitis severity. Am J Physiol Gastrointest Liver Physiol. 2002 Sep; 283 (3):G794-800
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78. Bhagat L, Singh VP, Song AM, van Acker GJ, Agrawal S, Steer ML, Saluja AK. Thermal stress-induced HSP70 mediates protection against intrapancreatic trypsinogen activation and acute pancreatitis in rats. Gastroenterology. 2002 Jan; 122 (1):156-65
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79. Frossard JL, Bhagat L, Lee HS, Hietaranta AJ, Singh VP, Song AM, Steer ML, Saluja AK. Both thermal and non-thermal stress protect against caerulein induced pancreatitis and prevent trypsinogen activation in the pancreas. Gut. 2002 Jan; 50 (1):78-83
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