Publications

1. Lembo AJ, Chey WD, Harris LA, Frazier R, Brenner DM, Chang L, Lacy BE, Edelstein S, Yang Y, Zhao S, Rosenbaum DP. Abdominal Symptom Improvement During Clinical Trials of Tenapanor in Patients With Irritable Bowel Syndrome With Constipation: A Post Hoc Analysis. Am J Gastroenterol. 2024 May 1; 119 (5):937-945 Epub 2024 Jan 31
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2. Chang L, Chey WD, Imdad A, Almario CV, Bharucha AE, Diem S, Greer KB, Hanson B, Harris LA, Ko C, Murad MH, Patel A, Shah ED, Lembo AJ, Sultan S. American Gastroenterological Association-American College of Gastroenterology Clinical Practice Guideline: Pharmacological Management of Chronic Idiopathic Constipation. Gastroenterology. 2023 Jun; 164 (7):1086-1106
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3. Chang L, Chey WD, Imdad A, Almario CV, Bharucha AE, Diem S, Greer KB, Hanson B, Harris LA, Ko C, Murad MH, Patel A, Shah ED, Lembo AJ, Sultan S. American Gastroenterological Association-American College of Gastroenterology Clinical Practice Guideline: Pharmacological Management of Chronic Idiopathic Constipation. Am J Gastroenterol. 2023 Jun 1; 118 (6):936-954 Epub 2023 May 19
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4. Harris LA, Chang CH. Burden of Constipation: Looking Beyond Bowel Movements. Am J Gastroenterol. 2022 Apr 1; 117 (4S):S2-S5
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5. Brenner DM, Harris LA, Chang CH, Waldman SA, Poppers DM, Kassebaum-Ladewski A, Sayuk GS. Real-World Treatment Strategies to Improve Outcomes in Patients With Chronic Idiopathic Constipation and Irritable Bowel Syndrome With Constipation. Am J Gastroenterol. 2022 Apr 1; 117 (4S):S21-S26
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6. Lunsford TN, Atia MA, Kagbo-Kue S, Harris LA. A Pain in the Butt: Hemorrhoids, Fissures, Fistulas, and Other Anorectal Syndromes. Gastroenterol Clin North Am. 2022 Mar; 51 (1):123-144 Epub 2022 Jan 08
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7. Grozic A, Coker K, Dussik CM, Sabir MS, Sabir Z, Bradley A, Zhang L, Park J, Yale S, Kaneko I, Hockley M, Harris LA, Lunsford TN, Sandrin TR, Jurutka PW. Identification of putative transcriptomic biomarkers in irritable bowel syndrome (IBS): Differential gene expression and regulation of TPH1 and SERT by vitamin D. PLoS One. 2022; 17 (10):e0275683 Epub 2022 Oct 20
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8. Rabinowitz LG, Grinspan LT, Zylberberg HM, Dixon R, David YN, Aroniadis OC, Chiang A, Christie J, Fayad NF, Ha C, Harris LA, Ko CW, Kolb J, Kwah J, Lee L, Lieberman D, Raffals LE, Rex DK, Shah SC, Siddiqui UD, Smith MS, Wallace M, Williams R, Woods K, Crowe SE, Kumta NA, Kim MK, Greenwald DA. Survey Finds Gender Disparities Impact Both Women Mentors and Mentees in Gastroenterology. Am J Gastroenterol. 2021 Sep 1; 116 (9):1876-1884
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9. Harris LA, Cash BD, Moftah K, Franklin H. An Open-label, Multicenter Study to Assess the Efficacy and Safety of a Novel Probiotic Blend in Patients With Functional Gastrointestinal Symptoms. J Clin Gastroenterol. 2021 May 24 [Epub ahead of print]
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10. Lucak S, Lunsford TN, Harris LA. Evaluation and Treatment of Constipation in the Geriatric Population. Clin Geriatr Med. 2021 Feb; 37 (1):85-102 Epub 2020 Nov 02
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11. Knuttinen MG, Zurcher KS, Khurana N, Patel I, Foxx-Orenstein A, Harris LA, Lawrence A, Aguilar F, Sichlau M, Smith BH, Smith SJ. Imaging findings of pelvic venous insufficiency in patients with postural orthostatic tachycardia syndrome. Phlebology. 2021 Feb; 36 (1):32-37 Epub 2020 Aug 05
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12. Maurer AH, Abell T, Bennett P, Diaz JR, Harris LA, Hasler W, Iagaru A, Koch KL, McCallum RW, Parkman HP, Rao SSC, Tulchinsky M. Appropriate Use Criteria for Gastrointestinal Transit Scintigraphy. J Nucl Med. 2020 Mar; 61 (3):11N-17N
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13. Tseng AS, Traub NA, Harris LA, Crowell MD, Hoffman-Snyder CR, Goodman BP, DiBaise JK. Factors Associated With Use of Nonoral Nutrition and Hydration Support in Adult Patients With Postural Tachycardia Syndrome. JPEN J Parenter Enteral Nutr. 2019 Aug; 43 (6):734-741 Epub 2018 Dec 18
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14. DiBaise JK, Lunsford TN, Harris LA. The POTS (Postural Tachycardia Syndrome) Epidemic: Hydration and Nutrition Issues. Pract Gastroenterol. 2019 Jun; 187:14-27.
    
15. Lacy BE, Harris LA, Chang L, Lucak S, Gutman C, Dove LS, Covington PS, Lembo A. Impact of patient and disease characteristics on the efficacy and safety of eluxadoline for IBS-D: a subgroup analysis of phase III trials. Therap Adv Gastroenterol. 2019; 12:1756284819841290 Epub 2019 Apr 15
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16. Ford AC, Lacy BE, Harris LA, Quigley EMM, Moayyedi P. Effect of Antidepressants and Psychological Therapies in Irritable Bowel Syndrome: An Updated Systematic Review and Meta-Analysis. Am J Gastroenterol. 2019 Jan; 114 (1):21-39
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17. Ford AC, Harris LA, Lacy BE, Quigley EMM, Moayyedi P. Systematic review with meta-analysis: the efficacy of prebiotics, probiotics, synbiotics and antibiotics in irritable bowel syndrome. Aliment Pharmacol Ther. 2018 Nov; 48 (10):1044-1060 Epub 2018 Oct 08
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18. DiBaise JK, Harris LA, Goodman B. Postural Tachycardia Syndrome (POTS) and the GI Tract: A Primer for the Gastroenterologist. Am J Gastroenterol. 2018 Oct; 113 (10):1458-1467 Epub 2018 Aug 03
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19. Firth C, Harris LA, Smith ML, Thomas LF. A Case Report of Cronkhite-Canada Syndrome Complicated by Membranous Nephropathy. Case Rep Nephrol Dial. 2018 Sep-Dec; 8 (3):261-267 Epub 2018 Nov 27
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20. Quigley EMM, Horn J, Kissous-Hunt M, Crozier RA, Harris LA. Better Understanding and Recognition of the Disconnects, Experiences, and Needs of Patients with Irritable Bowel Syndrome with Constipation (BURDEN IBS-C) Study: Results of an Online Questionnaire. Adv Ther. 2018 Jul; 35 (7):967-980 Epub 2018 June 26
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21. Ford AC, Moayyedi P, Chey WD, Harris LA, Lacy BE, Saito YA, Quigley EMM, ACG Task Force on Management of Irritable Bowel Syndrome. American College of Gastroenterology Monograph on Management of Irritable Bowel Syndrome. Am J Gastroenterol. 2018 Jun; 113 (Suppl 2):1-18
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22. Harris LA, Horn J, Kissous-Hunt M, Magnus L, Quigley EMM. The Better Understanding and Recognition of the Disconnects, Experiences, and Needs of Patients with Chronic Idiopathic Constipation (BURDEN-CIC) Study: Results of an Online Questionnaire. Adv Ther. 2017 Dec; 34 (12):2661-2673 Epub 2017 Nov 06
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23. Harris LA, Baffy N. Modulation of the gut microbiota: a focus on treatments for irritable bowel syndrome. Postgrad Med. 2017 Nov; 129 (8):872-888 Epub 2017 Oct 13
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24. Baffy N, Foxx-Orenstein AE, Harris LA, Sterler S. Intractable Constipation in the Elderly. Curr Treat Options Gastroenterol. 2017 Sep; 15 (3):363-381
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25. Goodman BP, Crepeau A, Dhawan PS, Khoury JA, Harris LA. Spectrum of Autonomic Nervous System Impairment in Sjogren Syndrome. Neurologist. 2017 Jul; 22 (4):127-130
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26. Lucak S, Chang L, Halpert A, Harris LA. Current and emergent pharmacologic treatments for irritable bowel syndrome with diarrhea: evidence-based treatment in practice. Therap Adv Gastroenterol. 2017 Feb; 10 (2):253-275 Epub 2016 Sept 16
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27. Stoven SA, Choung RS, Rubio-Tapia A, Absah I, Lam-Himlin DM, Harris LA, Ngamruengphong S, Vazquez Roque MI, Wu TT, Murray JA. Analysis of Biopsies From Duodenal Bulbs of All Endoscopy Patients Increases Detection of Abnormalities but has a Minimal Effect on Diagnosis of Celiac Disease. Clin Gastroenterol Hepatol. 2016 Nov; 14 (11):1582-1588 Epub 2016 Mar 07
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28. Harris LA, Umar SB, Baffy N, Heitkemper MM. Irritable Bowel Syndrome and Female Patients. Gastroenterol Clin North Am. 2016 Jun; 45 (2):179-204
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29. Harris LA. Treating Irritable Bowel Syndrome: A Fresh and Minty Approach to an Old Therapy. Dig Dis Sci 2016 Feb; 61 (2):334-6
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30. Franco DL, Disbrow MB, Kahn A, Koepke LM, Harris LA, Harrison ME, Crowell MD, Ramirez FC. Duodenal Aspirates for Small Intestine Bacterial Overgrowth: Yield, PPIs, and Outcomes after Treatment at a Tertiary Academic Medical Center. Gastroenterol Res Pract. 2015; 2015:971582 Epub 2015 Jan 28
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31. Kachaamy T, Dzeletovic I, Harris LA, Pasha SF. Jejunal hemangioma resection via double-balloon enteroscopy. Gastrointest Endosc. 2014 Nov; 80(5):899-900. Epub 2014 Mar 01.
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32. Ratuapli SK, Hansel SL, Umar SB, Burdick GE, Ramirez FC, Fleischer DE, Harris LA, Lacy BE, DiBaise JK, Crowell MD. Esophageal peristaltic defects in adults with functional dysphagia. Dysphagia. 2014 Aug; 29 (4):519-26 Epub 2014 June 04
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33. Dzeletovic I, Fleischer DE, Crowell MD, Pannala R, Harris LA, Ramirez FC, Burdick GE, Rentz LA, Spratley RV Jr, Helling SD, Alexander JA. Self-dilation as a treatment for resistant, benign esophageal strictures. Dig Dis Sci. 2013 Nov; 58 (11):3218-23 Epub 2013 Aug 08
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34. Dzeletovic I, Harrison ME, Crowell MD, Ramirez FC, Yows CR, Harris LA, Pasha SF, Gurudu SR, Leighton JA, Heigh RI. Impact of fentanyl in lieu of meperidine on endoscopy unit efficiency: a prospective comparative study in patients undergoing EGD. Gastrointest Endosc. 2013 Jun; 77(6):883-7. Epub 2013 Mar 06.
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35. Harris LA, Hansel SL, Rajan E, Srivathsan K, Rea R, Crowell MD, Fleischer DE, Pasha SF, Gurudu SR, Heigh RI, Shiff AD, Post JK, Leighton JA. Capsule Endoscopy in Patients with Implantable Electromedical Devices is Safe. Gastroenterol Res Pract. 2013; 2013:959234 Epub 2013 Apr 03
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36. Leffler DA, Kelly CP, Abdallah HZ, Colatrella AM, Harris LA, Leon F, Arterburn LA, Paterson BM, Lan ZH, Murray JA. A randomized, double-blind study of larazotide acetate to prevent the activation of celiac disease during gluten challenge. Am J Gastroenterol. 2012 Oct; 107(10):1554-62. Epub 2012 Jul 24.
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37. Harris LA, Park JY, Voltaggio L, Lam-Himlin D. Celiac disease: clinical, endoscopic, and histopathologic review. Gastrointest Endosc. 2012 Sep; 76 (3):625-40
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38. Quigley EM, Abdel-Hamid H, Barbara G, Bhatia SJ, Boeckxstaens G, De Giorgio R, Delvaux M, Drossman DA, Foxx-Orenstein AE, Guarner F, Gwee KA, Harris LA, Hungin AP, Hunt RH, Kellow JE, Khalif IL, Kruis W, Lindberg G, Olano C, Moraes-Filho JP, Schiller LR, Schmulson M, Simren M, Tzeuton C. A global perspective on irritable bowel syndrome: a consensus statement of the World Gastroenterology Organisation Summit Task Force on irritable bowel syndrome. J Clin Gastroenterol. 2012 May-Jun; 46(5):356-66.
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39. Ratuapli SK, Ellington TG, O'Neill MT, Umar SB, Harris LA, Foxx-Orenstein AE, Burdick GE, Dibaise JK, Lacy BE, Crowell MD. Proton pump inhibitor therapy use does not predispose to small intestinal bacterial overgrowth. Am J Gastroenterol. 2012 May; 107 (5):730-5 Epub 2012 Feb 14
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40. Harris LA, Heitkemper MM. Practical considerations for recognizing and managing severe irritable bowel syndrome. Gastroenterol Nurs. 2012 Jan-Feb; 35(1):12-21; quiz 22-3.
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41. Yadav A, Heigh RI, Hara AK, Decker GA, Crowell MD, Gurudu SR, Pasha SF, Fleischer DE, Harris LA, Post J, Leighton JA. Performance of the patency capsule compared with nonenteroclysis radiologic examinations in patients with known or suspected intestinal strictures. Gastrointest Endosc. 2011 Oct; 74 (4):834-9 Epub 2011 Aug 15
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42. Dzeletovic I, Fleischer DE, Crowell MD, Kim HJ, Harris LA, Burdick GE, McLaughlin RR, Spratley RV Jr, Sharma VK. Self dilation as a treatment for resistant benign esophageal strictures: outcome, technique, and quality of life assessment. Dig Dis Sci. 2011 Feb; 56 (2):435-40 Epub 2011 Jan 08
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43. Windgassen EB, Funtowicz L, Lunsford TN, Harris LA, Mulvagh SL. C-reactive protein and high-sensitivity C-reactive protein: an update for clinicians. Postgrad Med. 2011 Jan; 123 (1):114-9
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44. Pasha SF, Crowell MD, Alexander JA, Harris LA, Achem SR, Farrugia G, Lee JJ, Thompson DM, Jung KW, Kita H, Ravi K, Namasivayam V, Kim HJ, Fleischer DE, Sharma VK, Romero Y. Eosinophilic oesophagitis in adults - A rising epidemic. European Gastroenterology and Hepatology Review. 2011; 7(1):14-20.
    
45. Spiegel BM, Bolus R, Agarwal N, Sayuk G, Harris LA, Lucak S, Esrailian E, Chey WD, Lembo A, Karsan H, Tillisch K, Talley J, Chang L. Measuring symptoms in the irritable bowel syndrome: development of a framework for clinical trials. Aliment Pharmacol Ther. 2010 Nov; 32(10):1275-91. Epub 2010 Sep 28.
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46. Spiegel BM, Bolus R, Harris LA, Lucak S, Chey WD, Sayuk G, Esrailian E, Lembo A, Karsan H, Tillisch K, Talley J, Chang L. Characterizing abdominal pain in IBS: guidance for study inclusion criteria, outcome measurement and clinical practice. Aliment Pharmacol Ther. 2010 Nov; 32(9):1192-202. Epub 2010 Aug 30.
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47. Lunsford TN, Harris LA. Lubiprostone: evaluation of the newest medication for the treatment of adult women with constipation-predominant irritable bowel syndrome. Int J Womens Health. 2010 Oct 27; 2:361-74
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48. Hansel SL, Umar SB, Lunsford TN, Harris LA, Dibaise JK, Crowell MD. Personality traits and impaired health-related quality of life in patients with functional gastrointestinal disorders. Clin Gastroenterol Hepatol. 2010 Feb; 8(2):220-2. Epub 2009 Oct 20.
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49. Spiegel B, Bolus R, Harris LA, Lucak S, Naliboff B, Esrailian E, Chey WD, Lembo A, Karsan H, Tillisch K, Talley J, Mayer E, Chang L. Measuring irritable bowel syndrome patient-reported outcomes with an abdominal pain numeric rating scale. Aliment Pharmacol Ther. 2009 Dec 1; 30(11-12):1159-70. Epub 2009 Sep 12.
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50. Crowell MD, Harris LA, Lunsford TN, Dibaise JK. Emerging drugs for chronic constipation. Expert Opin Emerg Drugs. 2009 Sep; 14(3):493-504.
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51. Spiegel B, Harris L, Lucak S, Mayer E, Naliboff B, Bolus R, Esrailian E, Chey WD, Lembo A, Karsan H, Tillisch K, Dulai G, Talley J, Chang L. Developing valid and reliable health utilities in irritable bowel syndrome: results from the IBS PROOF Cohort. Am J Gastroenterol. 2009 Aug; 104(8):1984-91. Epub 2009 Jun 02.
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52. Protheroe C, Woodruff SA, de Petris G, Mukkada V, Ochkur SI, Janarthanan S, Lewis JC, Pasha S, Lunsford T, Harris L, Sharma VK, McGarry MP, Lee NA, Furuta GT, Lee JJ. A novel histologic scoring system to evaluate mucosal biopsies from patients with eosinophilic esophagitis. Clin Gastroenterol Hepatol. 2009 Jul; 7 (7):749-755.e11 Epub 2009 Apr 01
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53. Ravapati N, Mason M, Pockaj BA, Harris LA. Splenic trauma from colonoscopy - A case report and review of literature. Surgical Rounds. 2007 Dec; 12:566-70.
    
54. Harris LA, Crowell MD. Linaclotide, a new direction in the treatment of irritable bowel syndrome and chronic constipation. Curr Opin Mol Ther. 2007 Aug; 9 (4):403-10
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55. Crowell MD, Schettler VA, Lacy BE, Lunsford TN, Harris LA, DiBaise JK, Jones MP. Impact of anal incontinence on psychosocial function and health-related quality of life. Dig Dis Sci. 2007 Jul; 52 (7):1627-31 Epub 2007 Jan 09
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56. Harris LA, Chang L. Alosetron: an effective treatment for diarrhea-predominant irritable bowel syndrome. Womens Health (Lond). 2007 Jan; 3: (1)15-27.
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57. Crowell MD, Harris LA, DiBaise JK, Olden KW. Activation of type-2 chloride channels: a novel therapeutic target for the treatment of chronic constipation. Curr Opin Investig Drugs. 2007 Jan; 8 (1):66-70
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58. Drost J, Harris LA. Diagnosis and management of chronic constipation. JAAPA. 2006 Nov; 19 (11):24-9
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59. Harris LA, Hansel S, DiBaise J, Crowell MD. Irritable bowel syndrome and chronic constipation: emerging drugs, devices, and surgical treatments. Curr Gastroenterol Rep. 2006 Aug; 8 (4):282-90
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60. Chang L, Chey WD, Harris L, Olden K, Surawicz C, Schoenfeld P. Incidence of ischemic colitis and serious complications of constipation among patients using alosetron: systematic review of clinical trials and post-marketing surveillance data. Am J Gastroenterol. 2006 May; 101(5):1069-79.
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61. Harris LA. Current mechanisms of action in treatment of chronic constipation and irritable bowel syndrome... includes discussion. Advanced Studies in Medicine. 2006 Apr; 6(4A):S237-42, S251-3.
    
62. Harris LA, Chang L. Irritable bowel syndrome: new and emerging therapies. Curr Opin Gastroenterol. 2006 Mar; 22(2):128-35.
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63. Crowell MD, Harris L, Jones MP, Chang L. New insights into the pathophysiology of irritable bowel syndrome: implications for future treatments. Curr Gastroenterol Rep. 2005 Aug; 7 (4):272-9
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64. Harris LA. Prevalence and ramifications of chronic constipation. Manag Care Interface. 2005 Aug; 18(8):23-30.
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65. Harris LA. Chronic constipation: Mechanisms of action and effective treatment. Advanced Studies in Medicine. 2005; 5(10 B):S965-76.
    
66. Crowell MD, Jones MP, Harris LA, Dineen TN, Schettler VA, Olden KW. Antidepressants in the treatment of irritable bowel syndrome and visceral pain syndromes. Curr Opin Investig Drugs. 2004 Jul; 5 (7):736-42
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67. Harris LA, Chang L. Clinical update: IBS: improving diagnosis, serotonin signaling and improving diagnosis. http//www.medscape.com/viewprogram/2750. 2003 Oct 31;
    
68. Frissora C, Harris L. Approaching the diagnosis and treatment of irritable bowel syndrome. Emerg Med. 2001 Apr; 33(4):57-64.
    
69. Myers G, Ngoi SS, Cennerazzo W, Harris L, DeCosse JJ. Clostridial septicemia in an urban hospital. Surgery, Gynecology & Obstetrics. 1992 Apr; 174(4):291-6.
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70. Harris LA, DeCosse JJ, Dannenberg A. Abdominal actinomycosis: evaluation by computed tomography. Am J Gastroenterol. 1989 Feb; 84(2):198-200.
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