Publications

1. Palnitkar Harish Ravindra, Murphy Matthew, Yi Sui, Glaser Kevin, Manduca Armando, Welker Kirk, Campeau Norbert, Huston John III, Ehman Richard, Arani Arvin. Functional MR elastography measures visual cortex stiffening proportional to visual contrast intensity in regions of activation Imaging Neuroscience. 2024.
   
2. Arani A, Murphy MC, Bhopalwala H, Arunachalam SP, Rossman PJ, Trzasko JD, Glaser K, Sui Y, Gunderson T, Arruda-Olson AM, Manduca A, Kantarci K, Ehman RL, Araoz PA. Sex Differences in Aging-related Myocardial Stiffening Quantitatively Measured with MR Elastography. Radiol Cardiothorac Imaging. 2024 Jun; 6 (3):e230140
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3. Mark IT, Karki P, Cutsforth-Gregory J, Brinjikji W, Madhavan AA, Messina SA, Cogswell PM, Chen JJ, Ehman RL, Huston J, Murphy MC. Evaluation of MR Elastography as a Noninvasive Diagnostic Test for Spontaneous Intracranial Hypotension. AJNR Am J Neuroradiol. 2024 May 9; 45 (5):662-667 Epub 2024 May 09
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4. Karki P, Murphy MC, Cogswell PM, Senjem ML, Graff-Radford J, Elder BD, Perry A, Graffeo CS, Meyer FB, Jack CR Jr, Ehman RL, Huston J 3rd. Prediction of Surgical Outcomes in Normal Pressure Hydrocephalus by MR Elastography. AJNR Am J Neuroradiol. 2024 Mar 7; 45 (3):328-334 Epub 2024 Mar 07
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5. Feng Y, Murphy MC, Hojo E, Li F, Roberts N. Magnetic Resonance Elastography in the Study of Neurodegenerative Diseases. J Magn Reson Imaging. 2024 Jan; 59 (1):82-96 Epub 2023 Apr 21
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6. Pavuluri K, Huston J 3rd, Ehman RL, Manduca A, Jack CR Jr, Senjem ML, Vemuri P, Murphy MC. Associations between vascular health, brain stiffness and global cognitive function. Brain Commun. 2024; 6 (2):fcae073 Epub 2024 Feb 29
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7. Esterov D, Yin Z, Persaud T, Shan X, Murphy MC, Ehman RL, Huston J, Brown AW. Association Between Anatomic and Clinical Indicators of Injury Severity After Moderate-Severe Traumatic Brain Injury: A Pilot Study Using Multiparametric Magnetic Resonance Imaging. Neurotrauma Rep. 2024; 5 (1):232-242 Epub 2024 Mar 13
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8. Zheng K, Murphy MC, Camerucci E, Plitt AR, Shan X, Sui Y, Manduca A, Van Gompel JJ, Ehman RL, Huston J 3rd, Yin Z. Improved quantification of tumor adhesion in meningiomas using MR elastography-based slip interface imaging. PLoS One. 2024; 19 (6):e0305247 Epub 2024 June 25
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9. Karki P, Sincomb S, Murphy MC, Gunter JL, Senjem ML, Graff-Radford J, Jones DT, Botha H, Cutsforth-Gregory JK, Elder BD, Cogswell PM. Quantifying CSF dynamics disruption in idiopathic normal pressure hydrocephalus using phase lag between transmantle pressure and volumetric flow rate. Brain Multiphysics. 2024; 7:100101
   
10. Shan X, Murphy MC, Sui Y, Camerucci E, Zheng K, Manduca A, Ehman RL, Huston J, Yin Z. Magnetic Resonance Elastography-Based Technique to Assess the Biomechanics of the Skull-Brain Interface: Repeatability and Age-Sex Characteristics. J Neurotrauma. 2023 Oct; 40 (19-20):2193-2204 Epub 2023 July 18
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11. Camerucci E, Graff-Radford J, Jones DT, Elder BD, Gunter JL, Cutsforth-Gregory JK, Botha H, Murphy MC, Johnson DR, Davidge-Pitts C, Jack CR Jr, Huston J 3rd, Cogswell PM. Change in Morphological Features of Enlarged Subarachnoid Spaces Following Treatment in Idiopathic Normal Pressure Hydrocephalus. J Magn Reson Imaging. 2023 May; 57 (5):1443-1450 Epub 2022 July 27
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12. Pavuluri K, Scott JM, Huston Iii J, Ehman RL, Manduca A, Jack CR Jr, Savica R, Boeve BF, Kantarci K, Petersen RC, Knopman DS, Murphy MC. Differential effect of dementia etiology on cortical stiffness as assessed by MR elastography. Neuroimage Clin. 2023; 37:103328 Epub 2023 Jan 18
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13. Bang JW, Chan RW, Parra C, Murphy MC, Schuman JS, Nau AC, Chan KC. Diverging patterns of plasticity in the nucleus basalis of Meynert in early- and late-onset blindness. Brain Commun. 2023; 5 (2):fcad119 Epub 2023 Apr 11
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14. Cogswell PM, Murphy MC, Madhavan AA, Bhatti MT, Cutsforth-Gregory JK, Senjem ML, Huston J 3rd, Chen JJ. Features of Idiopathic Intracranial Hypertension on MRI With MR Elastography: Prospective Comparison With Control Individuals and Assessment of Postintervention Changes. AJR Am J Roentgenol. 2022 Dec; 219 (6):940-951 Epub 2022 July 13
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15. Arani A, Schwarz CG, Wiste HJ, Weigand SD, Cogswell PM, Murphy MC, Trzasko JD, Gunter JL, Senjem ML, McGee KP, Shu Y, Bernstein MA, Huston J 3rd, Jack CR Jr, Alzheimer's Disease Neuroimaging Initiative. Left-Right Intensity Asymmetries Vary Depending on Scanner Model for FLAIR and T1 Weighted MRI Images. J Magn Reson Imaging. 2022 Sep; 56(3):917-927. Epub 2022 Feb 08.
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16. Scott JM, Pavuluri K, Trzasko JD, Manduca A, Senjem ML, Huston J 3rd, Ehman RL, Murphy MC. Impact of material homogeneity assumption on cortical stiffness estimates by MR elastography. Magn Reson Med. 2022 Aug; 88 (2):916-929 Epub 2022 Apr 05
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17. Jones D, Lowe V, Graff-Radford J, Botha H, Barnard L, Wiepert D, Murphy MC, Murray M, Senjem M, Gunter J, Wiste H, Boeve B, Knopman D, Petersen R, Jack C. A computational model of neurodegeneration in Alzheimer's disease. Nat Commun. 2022 Mar 28; 13 (1):1643
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18. Cogswell PM, Murphy MC, Senjem ML, Botha H, Gunter JL, Elder BD, Graff-Radford J, Jones DT, Cutsforth-Gregory JK, Schwarz CG, Meyer FB, Huston J 3rd, Jack CR Jr. Changes in Ventricular and Cortical Volumes following Shunt Placement in Patients with Idiopathic Normal Pressure Hydrocephalus. AJNR Am J Neuroradiol. 2021 Dec; 42(12):2165-2171. Epub 2021 Oct 21.
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19. Chan RW, Won Bang J, Trivedi V, Murphy MC, Liu P, Wollstein G, Schuman JS, Chan KC. Relationships between cerebrovascular reactivity, visual-evoked functional activity, and resting-state functional connectivity in the visual cortex and basal forebrain in glaucoma. Annu Int Conf IEEE Eng Med Biol Soc. 2021 Nov; 2021:4037-4040
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20. van der Merwe Y, Murphy MC, Sims JR, Faiq MA, Yang XL, Ho LC, Conner IP, Yu Y, Leung CK, Wollstein G, Schuman JS, Chan KC. Citicoline Modulates Glaucomatous Neurodegeneration Through Intraocular Pressure-Independent Control. Neurotherapeutics. 2021 Apr; 18 (2):1339-1359 Epub 2021 Apr 13
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21. Sui Y, Arani A, Trzasko JD, Murphy MC, Rossman PJ, Glaser KJ, McGee KP, Manduca A, Ehman RL, Araoz PA, Huston J 3rd. TURBINE-MRE: A 3D hybrid radial-Cartesian EPI acquisition for MR elastography. Magn Reson Med. 2021 Feb; 85 (2):945-952 Epub 2020 Aug 01
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22. Scott JM, Arani A, Manduca A, McGee KP, Trzasko JD, Huston J 3rd, Ehman RL, Murphy MC. Artificial neural networks for magnetic resonance elastography stiffness estimation in inhomogeneous materials. Med Image Anal. 2020 Jul; 63:101710 Epub 2020 Apr 22
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23. Murphy MC, Cogswell PM, Trzasko JD, Manduca A, Senjem ML, Meyer FB, Ehman RL, Huston J 3rd. Identification of Normal Pressure Hydrocephalus by Disease-Specific Patterns of Brain Stiffness and Damping Ratio. Invest Radiol. 2020 Apr; 55 (4):200-208
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24. Yin Z, Murphy MC, Li J, Glaser KJ, Mauer AS, Mounajjed T, Therneau TM, Liu H, Malhi H, Manduca A, Ehman RL, Yin M. Prediction of nonalcoholic fatty liver disease (NAFLD) activity score (NAS) with multiparametric hepatic magnetic resonance imaging and elastography. Eur Radiol. 2019 Nov; 29 (11):5823-5831 Epub 2019 Mar 18
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25. Murphy MC, Huston J 3rd, Ehman RL. MR elastography of the brain and its application in neurological diseases. Neuroimage. 2019 Feb 15; 187:176-183 Epub 2017 Oct 07
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26. Murphy MC, Manduca A, Trzasko JD, Glaser KJ, Huston J 3rd, Ehman RL. Artificial neural networks for stiffness estimation in magnetic resonance elastography. Magn Reson Med. 2018 Jul; 80 (1):351-360 Epub 2017 Nov 28
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27. Murphy MC, Chan KC, Kim SG, Vazquez AL. Macroscale variation in resting-state neuronal activity and connectivity assessed by simultaneous calcium imaging, hemodynamic imaging and electrophysiology. Neuroimage. 2018 Apr 1; 169:352-362 Epub 2017 Dec 22
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28. Eles JR, Vazquez AL, Snyder NR, Lagenaur C, Murphy MC, Kozai TD, Cui XT. Neuroadhesive L1 coating attenuates acute microglial attachment to neural electrodes as revealed by live two-photon microscopy. Biomaterials. 2017 Jan; 113:279-292.
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29. O'Connell C, Ho LC, Murphy MC, Conner IP, Wollstein G, Cham R, Chan KC. Structural and functional correlates of visual field asymmetry in the human brain by diffusion kurtosis MRI and functional MRI. Neuroreport. 2016 Nov 09; 27: (16)1225-31.
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30. Murphy MC, Conner IP, Teng CY, Lawrence JD, Safiullah Z, Wang B, Bilonick RA, Kim SG, Wollstein G, Schuman JS, Chan KC. Retinal Structures and Visual Cortex Activity are Impaired Prior to Clinical Vision Loss in Glaucoma. Sci Rep. 2016 Aug 11; 6:31464.
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31. Huston J 3rd, Murphy MC, Boeve BF, Fattahi N, Arani A, Glaser KJ, Manduca A, Jones DT, Ehman RL. Magnetic resonance elastography of frontotemporal dementia. J Magn Reson Imaging. 2016 Feb; 43 (2):474-8 Epub 2015 June 30
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32. Murphy MC, Nau AC, Fisher C, Kim SG, Schuman JS, Chan KC. Top-down influence on the visual cortex of the blind during sensory substitution. Neuroimage. 2016 Jan 15; 125:932-40.
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33. Murphy MC, Poplawsky AJ, Chan KC. Kim SG. Improved spatial specificity of BOLD-fMRI activation maps in the olfactory bulb using supervised machine learning Neuroimage.2016;137:1-8.
    
34. Murphy MC, Jones DT, Jack CR Jr, Glaser KJ, Senjem ML, Manduca A, Felmlee JP, Carter RE, Ehman RL, Huston J 3rd. Regional brain stiffness changes across the Alzheimer's disease spectrum. Neuroimage Clin. 2016; 10:283-90 Epub 2015 Dec 19
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35. Poplawsky AJ, Fukuda M, Murphy M, Kim SG. Layer-Specific fMRI Responses to Excitatory and Inhibitory Neuronal Activities in the Olfactory Bulb. J Neurosci. 2015 Nov 18; 35: (46)15263-75.
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36. Nau AC, Murphy MC, Chan KC. Use of sensory substitution devices as a model system for investigating cross-modal neuroplasticity in humans. Neural Regen Res. 2015 Nov; 10: (11)1717-9.
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37. Arani A, Murphy MC, Glaser KJ, Manduca A, Lake DS, Kruse SA, Jack CR Jr, Ehman RL, Huston J 3rd. Measuring the effects of aging and sex on regional brain stiffness with MR elastography in healthy older adults. Neuroimage. 2015 May 1; 111:59-64 Epub 2015 Feb 17
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38. Vazquez AL, Murphy MC, Kim SG. Neuronal and physiological correlation to hemodynamic resting-state fluctuations in health and disease. Brain Connect. 2014 Nov; 4: (9)727-40.
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39. Chen J, Woodrum DA, Glaser KJ, Murphy MC, Gorny K, Ehman R. Assessment of in vivo laser ablation using MR elastography with an inertial driver. Magn Reson Med. 2014 Jul; 72 (1):59-67 Epub 2013 July 31
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40. Raman MR, Preboske GM, Przybelski SA, Gunter JL, Senjem ML, Vemuri P, Murphy MC, Murray ME, Boeve BF, Knopman DS, Petersen RC, Parisi JE, Dickson DW, Jack CR Jr, Kantarci K. Antemortem MRI findings associated with microinfarcts at autopsy. Neurology. 2014 Jun 3; 82 (22):1951-8 Epub 2014 May 02
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41. Whitwell JL, Jack CR Jr, Duffy JR, Strand EA, Gunter JL, Senjem ML, Murphy MC, Kantarci K, Machulda MM, Lowe VJ, Josephs KA. Microbleeds in the logopenic variant of primary progressive aphasia. Alzheimers Dement. 2014 Jan; 10 (1):62-6 Epub 2013 Apr 03
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42. Whitwell JL, Lowe VJ, Duffy JR, Strand EA, Machulda MM, Kantarci K, Wille SM, Senjem ML, Murphy MC, Gunter JL, Jack CR Jr, Josephs KA. Elevated occipital beta-amyloid deposition is associated with widespread cognitive impairment in logopenic progressive aphasia. J Neurol Neurosurg Psychiatry. 2013 Dec; 84 (12):1357-64 Epub 2013 Aug 14
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43. Kantarci K, Weigand SD, Przybelski SA, Preboske GM, Pankratz VS, Vemuri P, Senjem ML, Murphy MC, Gunter JL, Machulda MM, Ivnik RJ, Roberts RO, Boeve BF, Rocca WA, Knopman DS, Petersen RC, Jack CR Jr. MRI and MRS predictors of mild cognitive impairment in a population-based sample. Neurology. 2013 Jul 9; 81 (2):126-33 Epub 2013 June 12
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44. Raz L, Jayachandran M, Tosakulwong N, Lesnick TG, Wille SM, Murphy MC, Senjem ML, Gunter JL, Vemuri P, Jack CR Jr, Miller VM, Kantarci K. Thrombogenic microvesicles and white matter hyperintensities in postmenopausal women. Neurology. 2013 Mar 5; 80 (10):911-8 Epub 2013 Feb 13
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45. Murphy MC, Huston J 3rd, Glaser KJ, Manduca A, Meyer FB, Lanzino G, Morris JM, Felmlee JP, Ehman RL. Preoperative assessment of meningioma stiffness using magnetic resonance elastography. J Neurosurg. 2013 Mar; 118 (3):643-8 Epub 2012 Oct 19
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46. Murphy MC, Huston J 3rd, Jack CR Jr, Glaser KJ, Senjem ML, Chen J, Manduca A, Felmlee JP, Ehman RL. Measuring the characteristic topography of brain stiffness with magnetic resonance elastography. PLoS One. 2013; 8 (12):e81668 Epub 2013 Dec 02
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47. Murray ME, Vemuri P, Preboske GM, Murphy MC, Schweitzer KJ, Parisi JE, Jack CR Jr, Dickson DW. A quantitative postmortem MRI design sensitive to white matter hyperintensity differences and their relationship with underlying pathology. J Neuropathol Exp Neurol. 2012 Dec; 71 (12):1113-22
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48. Murphy MC, Curran GL, Glaser KJ, Rossman PJ, Huston J 3rd, Poduslo JF, Jack CR Jr, Felmlee JP, Ehman RL. Magnetic resonance elastography of the brain in a mouse model of Alzheimer's disease: initial results. Magn Reson Imaging. 2012 May; 30 (4):535-9 Epub 2012 Feb 10
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49. Jones DT, Vemuri P, Murphy MC, Gunter JL, Senjem ML, Machulda MM, Przybelski SA, Gregg BE, Kantarci K, Knopman DS, Boeve BF, Petersen RC, Jack CR Jr. Non-stationarity in the "resting brain's" modular architecture. PLoS One. 2012; 7 (6):e39731 Epub 2012 June 28
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50. Murphy MC, Huston J 3rd, Jack CR Jr, Glaser KJ, Manduca A, Felmlee JP, Ehman RL. Decreased brain stiffness in Alzheimer's disease determined by magnetic resonance elastography. J Magn Reson Imaging. 2011 Sep; 34 (3):494-8 Epub 2011 July 12
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51. Murphy MC, Glaser KJ, Manduca A, Felmlee JP, Huston J 3rd, Ehman RL. Analysis of time reduction methods for magnetic resonance elastography of the brain. Magn Reson Imaging. 2010 Dec; 28 (10):1514-24
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