Publications

1. Hassan S, Anouti A, Tan QK, Wangensteen K, Aqul A. Liver transplantation for pediatric genetic and metabolic disorders. Liver Transpl. 2024 Aug 23 [Epub ahead of print]
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2. Chotiprasidhi P, Sato-Espinoza AK, Wangensteen KJ. Germline Genetic Associations for Hepatobiliary Cancers. Cell Mol Gastroenterol Hepatol. 2024; 17 (4):623-638 Epub 2023 Dec 30
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3. Vell MS, Krishnan A, Wangensteen K, Serper M, Seeling KS, Hehl L, Rendel MD, Zandvakili I, Vujkovic M, Scorletti E, Creasy KT, Trautwein C, Rader DJ, Alqahtani S, Schneider KM, Schneider CV. Aspirin is associated with a reduced incidence of liver disease in men. Hepatol Commun. 2023 Oct 1; 7 (10) Epub 2023 Sept 15
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4. Adlat S, Vazquez Salgado AM, Lee M, Yin D, Wangensteen KJ. Emerging and potential use of CRISPR in human liver disease. Hepatology. 2023 Aug 22 [Epub ahead of print]
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5. Lau-Min KS, Bleznuck J, Wollack C, McKenna DB, Long JM, Hubert AP, Johnson M, Rochester SE, Constantino G, Dudzik C, Doucette A, Wangensteen K, Domchek SM, Landgraf J, Chen J, Nathanson KL, Katona BW. Development of an Electronic Health Record-Based Clinical Decision Support Tool for Patients With Lynch Syndrome. JCO Clin Cancer Inform. 2023 Aug; 7:e2300024
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6. Schneider CV, Li T, Zhang D, Mezina AI, Rattan P, Huang H, Creasy KT, Scorletti E, Zandvakili I, Vujkovic M, Hehl L, Fiksel J, Park J, Wangensteen K, Risman M, Chang KM, Serper M, Carr RM, Schneider KM, Chen J, Rader DJ. Large-scale identification of undiagnosed hepatic steatosis using natural language processing. EClinicalMedicine. 2023 Aug; 62:102149 Epub 2023 Aug 09
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7. Vell MS, Loomba R, Krishnan A, Wangensteen KJ, Trebicka J, Creasy KT, Trautwein C, Scorletti E, Seeling KS, Hehl L, Rendel MD, Zandvakili I, Li T, Chen J, Vujkovic M, Alqahtani S, Rader DJ, Schneider KM, Schneider CV. Association of Statin Use With Risk of Liver Disease, Hepatocellular Carcinoma, and Liver-Related Mortality. JAMA Netw Open. 2023 Jun 1; 6 (6):e2320222 Epub 2023 June 01
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8. Saito Y, Yin D, Kubota N, Wang X, Filliol A, Remotti H, Nair A, Fazlollahi L, Hoshida Y, Tabas I, Wangensteen KJ, Schwabe RF. A Therapeutically Targetable TAZ-TEAD2 Pathway Drives the Growth of Hepatocellular Carcinoma via ANLN and KIF23. Gastroenterology. 2023 Jun; 164 (7):1279-1292 Epub 2023 Mar 07
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9. Haley RM, Chan A, Billingsley MM, Gong N, Padilla MS, Kim EH, Wang H, Yin D, Wangensteen KJ, Tsourkas A, Mitchell MJ. Lipid Nanoparticle Delivery of Small Proteins for Potent In Vivo RAS Inhibition. ACS Appl Mater Interfaces. 2023 May 10; 15 (18):21877-21892 Epub 2023 Apr 28
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10. Williams S, Ebrahimzadeh JE, Clay D, Constantino G, Heiman J, Wangensteen KJ, Valverde K, Mahmud N, Katona BW. Comparing telemedicine and in-person gastrointestinal cancer genetic appointment outcomes during the COVID-19 pandemic. Hered Cancer Clin Pract. 2023 May 8; 21 (1):6 Epub 2023 May 08
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11. Sequera C, Grattarola M, Holczbauer A, Dono R, Pizzimenti S, Barrera G, Wangensteen KJ, Maina F. MYC and MET cooperatively drive hepatocellular carcinoma with distinct molecular traits and vulnerabilities. Cell Death Dis. 2022 Nov 24; 13 (11):994
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12. Holczbauer A, Wangensteen KJ, Shin S. Cellular origins of regenerating liver and hepatocellular carcinoma. JHEP Rep. 2022 Apr; 4 (4):100416 Epub 2021 Dec 13
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13. Vazquez Salgado AM, Preziosi ME, Yin D, Holczbauer A, Zahm AM, Erez N, Kieckhaefer J, Ackerman D, Gade TP, Kaestner KH, Wangensteen KJ. In Vivo Screen Identifies Liver X Receptor Alpha Agonism Potentiates Sorafenib Killing of Hepatocellular Carcinoma. Gastro Hep Adv. 2022; 1 (5):905-908 Epub 2022 June 01
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14. DeJesse J, Vajravelu RK, Dudzik C, Constantino G, Long JM, Wangensteen KJ, Valverde KD, Katona BW. Uptake and outcomes of small intestinal and urinary tract cancer surveillance in Lynch syndrome. World J Clin Oncol. 2021 Nov 24; 12 (11):1023-1036
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15. Katona BW, Long JM, Ahmad NA, Attalla S, Bradbury AR, Carpenter EL, Clark DF, Constantino G, Das KK, Domchek SM, Dudzik C, Ebrahimzadeh J, Ginsberg GG, Heiman J, Kochman ML, Maxwell KN, McKenna DB, Powers J, Shah PD, Wangensteen KJ, Rustgi AK. EUS-based Pancreatic Cancer Surveillance in BRCA1/BRCA2/PALB2/ATM Carriers Without a Family History of Pancreatic Cancer. Cancer Prev Res (Phila). 2021 Nov; 14 (11):1033-1040 Epub 2021 Aug 02
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16. Yu H, Wangensteen K, Deng T, Li Y, Luo W. MRGPRX4 in Cholestatic Pruritus. Semin Liver Dis. 2021 Aug; 41 (3):358-367 Epub 2021 June 23
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17. Ricciotti E, Wangensteen KJ, FitzGerald GA. Aspirin in Hepatocellular Carcinoma. Cancer Res. 2021 Jul 15; 81 (14):3751-3761 Epub 2021 Apr 23
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18. Wangensteen KJ, Chang KM. Multiple Roles for Hepatitis B and C Viruses and the Host in the Development of Hepatocellular Carcinoma. Hepatology. 2021 Jan; 73 Suppl 1:27-37 Epub 2020 Nov 07
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19. Mezina A, Philips N, Bogus Z, Erez N, Xiao R, Fan R, Olthoff KM, Reddy KR, Samadder NJ, Nielsen SM, Hatchell KE, Esplin ED, Rustgi AK, Katona BW, Hoteit MA, Nathanson KL, Wangensteen KJ. Multigene Panel Testing in Individuals With Hepatocellular Carcinoma Identifies Pathogenic Germline Variants. JCO Precis Oncol. 2021; 5 Epub 2021 June 10
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20. Kumar S, Dudzik CM, Reed M, Long JM, Wangensteen KJ, Katona BW. Upper Endoscopic Surveillance in Lynch Syndrome Detects Gastric and Duodenal Adenocarcinomas. Cancer Prev Res (Phila). 2020 Dec; 13 (12):1047-1054 Epub 2020 Aug 28
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21. Zahm AM, Wang AW, Wang YJ, Schug J, Wangensteen KJ, Kaestner KH. A High-Content Screen Identifies MicroRNAs That Regulate Liver Repopulation After Injury in Mice. Gastroenterology. 2020 Mar; 158 (4):1044-1057.e17 Epub 2019 Nov 20
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22. Wang AW, Wang YJ, Zahm AM, Morgan AR, Wangensteen KJ, Kaestner KH. The Dynamic Chromatin Architecture of the Regenerating Liver. Cell Mol Gastroenterol Hepatol. 2020; 9 (1):121-143 Epub 2019 Oct 17
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23. Wang AW, Zahm AM, Wangensteen KJ. Cell Type-specific Gene Expression Profiling in the Mouse Liver. J Vis Exp. 2019 Sep 17; (151) Epub 2019 Sept 17
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24. Mahmud N, Wangensteen KJ. Colocolic intussusception. Arab J Gastroenterol. 2019 Jun; 20 (2):107-108 Epub 2019 Feb 04
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25. Kieckhaefer JE, Maina F, Wells RG, Wangensteen KJ. Liver Cancer Gene Discovery Using Gene Targeting, Sleeping Beauty, and CRISPR/Cas9. Semin Liver Dis. 2019 May; 39 (2):261-274 Epub 2019 Mar 25
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26. Wangensteen KJ, Wang YJ, Dou Z, Wang AW, Mosleh-Shirazi E, Horlbeck MA, Gilbert LA, Weissman JS, Berger SL, Kaestner KH. Combinatorial genetics in liver repopulation and carcinogenesis with a in vivo CRISPR activation platform. Hepatology. 2018 Aug; 68 (2):663-676 Epub 2018 May 14
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27. Wang AW, Wangensteen KJ, Wang YJ, Zahm AM, Moss NG, Erez N, Kaestner KH. TRAP-seq identifies cystine/glutamate antiporter as a driver of recovery from liver injury. J Clin Invest. 2018 Jun 1; 128 (6):2297-2309 Epub 2018 Apr 30
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28. Shoshkes-Carmel M, Wang YJ, Wangensteen KJ, Toth B, Kondo A, Massasa EE, Itzkovitz S, Kaestner KH. Subepithelial telocytes are an important source of Wnts that supports intestinal crypts. Nature. 2018 May; 557 (7704):242-246 Epub 2018 May 02
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29. Wang C, Chen WJ, Wu YF, You P, Zheng SY, Liu CC, Xiang D, Wang MJ, Cai YC, Zhao QH, Borjigin U, Liu W, Xiong WJ, Wangensteen KJ, Wang X, Liu ZM, He ZY. The extent of liver injury determines hepatocyte fate toward senescence or cancer. Cell Death Dis. 2018 May 1; 9 (5):575 Epub 2018 May 01
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30. Mahmud N, Wangensteen KJ. Endoscopic Band Ligation to Treat a Massive Hemorrhoidal Hemorrhage Following a Transrectal Ultrasound-Guided Prostate Biopsy. Ann Coloproctol. 2018 Feb; 34 (1):47-51 Epub 2018 Feb 28
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31. Wang MJ, Chen F, Liu QG, Liu CC, Yao H, Yu B, Zhang HB, Yan HX, Ye Y, Chen T, Wangensteen KJ, Wang X, Hu YP, He ZY. Insulin-like growth factor 2 is a key mitogen driving liver repopulation in mice. Cell Death Dis. 2018 Jan 18; 9 (2):26
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32. Dou Z, Ghosh K, Vizioli MG, Zhu J, Sen P, Wangensteen KJ, Simithy J, Lan Y, Lin Y, Zhou Z, Capell BC, Xu C, Xu M, Kieckhaefer JE, Jiang T, Shoshkes-Carmel M, Tanim KMAA, Barber GN, Seykora JT, Millar SE, Kaestner KH, Garcia BA, Adams PD, Berger SL. Cytoplasmic chromatin triggers inflammation in senescence and cancer. Nature. 2017 Oct 19; 550 (7676):402-406 Epub 2017 Oct 04
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33. Shin S, Wangensteen KJ, Teta-Bissett M, Wang YJ, Mosleh-Shirazi E, Buza EL, Greenbaum LE, Kaestner KH. Genetic lineage tracing analysis of the cell of origin of hepatotoxin-induced liver tumors in mice. Hepatology. 2016 Oct; 64 (4):1163-1177 Epub 2016 May 28
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34. De Luca-Johnson J, Wangensteen KJ, Hanson J, Krawitt E, Wilcox R. Natural History of Patients Presenting with Autoimmune Hepatitis and Coincident Nonalcoholic Fatty Liver Disease. Dig Dis Sci. 2016 Sep; 61 (9):2710-20 Epub 2016 June 04
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35. Ni J, Wangensteen KJ, Nelsen D, Balciunas D, Skuster KJ, Urban MD, Ekker SC. Active recombinant Tol2 transposase for gene transfer and gene discovery applications. Mob DNA. 2016; 7:6 Epub 2016 Mar 31
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36. Wangensteen KJ, Krawitt EL, Hamill RW, Boyd JT. Parkinsonism in Patients With Chronic Hepatitis C Treated With Interferons: Case Reports and Review of the Literature. Clin Neuropharmacol. 2016 Jan-Feb; 39 (1):1-5
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37. Wangensteen L, Wangensteen KJ, Evans SG, Everts LE, Trooskin SB. Hepatitis C: How to fine-tune your approach. J Fam Pract. 2015 Sep; 64 (9):535-40
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38. Wangensteen KJ, Fogt F, Kann BR, Osterman MT. Idiopathic Myointimal Hyperplasia of the Mesenteric Veins Diagnosed Preoperatively. J Clin Gastroenterol. 2015 Jul; 49 (6):491-4
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39. Wangensteen KJ, Zhang S, Greenbaum LE, Kaestner KH. A genetic screen reveals Foxa3 and TNFR1 as key regulators of liver repopulation. Genes Dev. 2015 May 1; 29 (9):904-9
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40. Wang MJ, Chen F, Li JX, Liu CC, Zhang HB, Xia Y, Yu B, You P, Xiang D, Lu L, Yao H, Borjigin U, Yang GS, Wangensteen KJ, He ZY, Wang X, Hu YP. Reversal of hepatocyte senescence after continuous in vivo cell proliferation. Hepatology. 2014 Jul; 60 (1):349-61 Epub 2014 May 28
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41. Xiang D, Liu CC, Wang MJ, Li JX, Chen F, Yao H, Yu B, Lu L, Borjigin U, Chen YX, Zhong L, Wangensteen KJ, He ZY, Wang X, Hu YP. Non-viral FoxM1 gene delivery to hepatocytes enhances liver repopulation. Cell Death Dis. 2014 May 22; 5:e1252
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42. Yu B, He ZY, You P, Han QW, Xiang D, Chen F, Wang MJ, Liu CC, Lin XW, Borjigin U, Zi XY, Li JX, Zhu HY, Li WL, Han CS, Wangensteen KJ, Shi Y, Hui LJ, Wang X, Hu YP. Reprogramming fibroblasts into bipotential hepatic stem cells by defined factors. Cell Stem Cell. 2013 Sep 5; 13 (3):328-40 Epub 2013 July 18
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43. He ZY, Deng L, Li YF, Xiang D, Hu JK, Chen YX, Wang MJ, Chen F, Liu CC, Li WL, Zi XY, Wu X, Li GP, Wangensteen KJ, Hu YP, Wang X. Murine embryonic stem cell-derived hepatocytes correct metabolic liver disease after serial liver repopulation. Int J Biochem Cell Biol. 2012 Apr; 44 (4):648-58 Epub 2012 Jan 10
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44. Li F, He Z, Li Y, Liu P, Chen F, Wang M, Zhu H, Ding X, Wangensteen KJ, Hu Y, Wang X. Combined activin A/LiCl/Noggin treatment improves production of mouse embryonic stem cell-derived definitive endoderm cells. J Cell Biochem. 2011 Apr; 112 (4):1022-34
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45. Li F, Liu P, Liu C, Xiang D, Deng L, Li W, Wangensteen K, Song J, Ma Y, Hui L, Wei L, Li L, Ding X, Hu Y, He Z, Wang X. Hepatoblast-like progenitor cells derived from embryonic stem cells can repopulate livers of mice. Gastroenterology. 2010 Dec; 139 (6):2158-2169.e8 Epub 2010 Aug 27
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46. He Z, Zhang H, Zhang X, Xie D, Chen Y, Wangensteen KJ, Ekker SC, Firpo M, Liu C, Xiang D, Zi X, Hui L, Yang G, Ding X, Hu Y, Wang X. Liver xeno-repopulation with human hepatocytes in Fah-/-Rag2-/- mice after pharmacological immunosuppression. Am J Pathol. 2010 Sep; 177 (3):1311-9 Epub 2010 July 22
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47. Wangensteen KJ, Kalliainen LK. Collagen tube conduits in peripheral nerve repair: a retrospective analysis. Hand (N Y). 2010 Sep; 5 (3):273-7 Epub 2009 Nov 24
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48. Keng VW, Ryan BJ, Wangensteen KJ, Balciunas D, Schmedt C, Ekker SC, Largaespada DA. Efficient transposition of Tol2 in the mouse germline. Genetics. 2009 Dec; 183 (4):1565-73 Epub 2009 Oct 05
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49. Wangensteen KJ, Wilber A, Keng VW, He Z, Matise I, Wangensteen L, Carson CM, Chen Y, Steer CJ, McIvor RS, Largaespada DA, Wang X, Ekker SC. A facile method for somatic, lifelong manipulation of multiple genes in the mouse liver. Hepatology. 2008 May; 47 (5):1714-24
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50. Wilber A, Wangensteen KJ, Chen Y, Zhuo L, Frandsen JL, Bell JB, Chen ZJ, Ekker SC, McIvor RS, Wang X. Messenger RNA as a source of transposase for sleeping beauty transposon-mediated correction of hereditary tyrosinemia type I. Mol Ther. 2007 Jul; 15 (7):1280-7 Epub 2007 Apr 17
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51. Balciunas D, Wangensteen KJ, Wilber A, Bell J, Geurts A, Sivasubbu S, Wang X, Hackett PB, Largaespada DA, McIvor RS, Ekker SC. Harnessing a high cargo-capacity transposon for genetic applications in vertebrates. PLoS Genet. 2006 Nov 10; 2 (11):e169 Epub 2006 Aug 28
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52. Sivasubbu S, Balciunas D, Davidson AE, Pickart MA, Hermanson SB, Wangensteen KJ, Wolbrink DC, Ekker SC. Gene-breaking transposon mutagenesis reveals an essential role for histone H2afza in zebrafish larval development. Mech Dev. 2006 Jul; 123 (7):513-29 Epub 2006 June 09
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53. Wilber A, Frandsen JL, Wangensteen KJ, Ekker SC, Wang X, McIvor RS. Dynamic gene expression after systemic delivery of plasmid DNA as determined by in vivo bioluminescence imaging. Hum Gene Ther. 2005 Nov; 16 (11):1325-32
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