Publications

1. Karri S, Dickinson Q, Jia J, Yang Y, Gan H, Wang Z, Deng Y, Yu C. The role of hexokinases in epigenetic regulation: altered hexokinase expression and chromatin stability in yeast. Epigenetics Chromatin. 2024 Aug 27; 17 (1):27
   View PubMed
2. Karri S, Yang Y, Zhou J, Dickinson Q, Jia J, Huang Y, Wang Z, Gan H, Yu C. Defective transfer of parental histone decreases frequency of homologous recombination by increasing free histone pools in budding yeast. Nucleic Acids Res. 2024 May 22; 52 (9):5138-5151
   View PubMed
3. Zhang T, Ambrodji A, Huang H, Bouchonville KJ, Etheridge AS, Schmidt RE, Bembenek BM, Temesgen ZB, Wang Z, Innocenti F, Stroka D, Diasio RB, Largiader CR, Offer SM. Germline cis variant determines epigenetic regulation of the anti-cancer drug metabolism gene dihydropyrimidine dehydrogenase (DPYD). Elife. 2024 Apr 30; 13
   View PubMed
4. Wen Q, Zhou J, Tian C, Li X, Song G, Gao Y, Sun Y, Ma C, Yao S, Liang X, Kang X, Wang N, Yao Y, Wang H, Liang X, Tang J, Offer SM, Lei X, Yu C, Liu X, Liu Z, Wang Z, Gan H. Symmetric inheritance of parental histones contributes to safeguarding the fate of mouse embryonic stem cells during differentiation. Nat Genet. 2023 Sep; 55 (9):1555-1566 Epub 2023 Sept 04
   View PubMed
5. Tian C, Zhou J, Li X, Gao Y, Wen Q, Kang X, Wang N, Yao Y, Jiang J, Song G, Zhang T, Hu S, Liao J, Yu C, Wang Z, Liu X, Pei X, Chan K, Liu Z, Gan H. Impaired histone inheritance promotes tumor progression. Nat Commun. 2023 Jun 10; 14 (1):3429 Epub 2023 June 10
   View PubMed
6. Wang Z, Yan H, Boysen JC, Secreto CR, Tschumper RC, Ali D, Guo Q, Zhong J, Zhou J, Gan H, Yu C, Jelinek DF, Slager SL, Parikh SA, Braggio E, Kay NE. B cell receptor signaling drives APOBEC3 expression via direct enhancer regulation in chronic lymphocytic leukemia B cells. Blood Cancer J. 2022 Jul 1; 12 (7):99 Epub 2022 July 01
   View PubMed
7. Li X, Zhou J, Zhao W, Wen Q, Wang W, Peng H, Gao Y, Bouchonville KJ, Offer SM, Chan K, Wang Z, Li N, Gan H. Defining Proximity Proteome of Histone Modifications by Antibody-mediated Protein A-APEX2 Labeling. Genomics Proteomics Bioinformatics. 2022 Feb; 20 (1):87-100 Epub 2021 Sept 30
   View PubMed
8. Wang Z, Wu R, Nie Q, Bouchonville KJ, Diasio RB, Offer SM. Chromatin assembly factor 1 suppresses epigenetic reprogramming toward adaptive drug resistance. J Natl Cancer Cent. 2021 Mar; 1 (1):15-22 Epub 2021 Jan 16
   View PubMed
9. Sinha S, Secreto CR, Boysen JC, Lesnick C, Wang Z, Ding W, Call TG, Kenderian SJ, Parikh SA, Warner SL, Bearss DJ, Ghosh AK, Kay NE. Upregulation of AXL and beta-catenin in chronic lymphocytic leukemia cells cultured with bone marrow stroma cells is associated with enhanced drug resistance. Blood Cancer J 2021 Feb 18; 11 (2):37
   View PubMed
10. Yan H, Tian S, Kleinstern G, Wang Z, Lee JH, Boddicker NJ, Cerhan JR, Kay NE, Braggio E, Slager SL. Chronic lymphocytic leukemia (CLL) risk is mediated by multiple enhancer variants within CLL risk loci. Hum Mol Genet. 2020 Sep 29; 29 (16):2761-2774
    View PubMed
11. Nie Q, Shrestha S, Tapper EE, Trogstad-Isaacson CS, Bouchonville KJ, Lee AM, Wu R, Jerde CR, Wang Z, Kubica PA, Offer SM, Diasio RB. Quantitative Contribution of rs75017182 to Dihydropyrimidine Dehydrogenase mRNA Splicing and Enzyme Activity. Clin Pharmacol Ther. 2017 Oct; 102 (4):662-670 Epub 2017 May 26
    View PubMed
12. Zhang H, Gan H, Wang Z, Lee JH, Zhou H, Ordog T, Wold MS, Ljungman M, Zhang Z. RPA Interacts with HIRA and Regulates H3.3 Deposition at Gene Regulatory Elements in Mammalian Cells. Mol Cell. 2017 Jan 19; 65 (2):272-284
    View PubMed
13. Wu R, Wang Z, Zhang H, Gan H, Zhang Z. H3K9me3 demethylase Kdm4d facilitates the formation of pre-initiative complex and regulates DNA replication. Nucleic Acids Res. 2017 Jan 9; 45 (1):169-180 Epub 2016 Sept 26
    View PubMed
14. Fang D, Gan H, Lee JH, Han J, Wang Z, Riester SM, Jin L, Chen J, Zhou H, Wang J, Zhang H, Yang N, Bradley EW, Ho TH, Rubin BP, Bridge JA, Thibodeau SN, Ordog T, Chen Y, van Wijnen AJ, Oliveira AM, Xu RM, Westendorf JJ, Zhang Z. The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas. Science. 2016 Jun 10; 352 (6291):1344-8 Epub 2016 May 26
    View PubMed
15. Wang Z, Zhang H, Liu J, Cheruiyot A, Lee JH, Ordog T, Lou Z, You Z, Zhang Z. USP51 deubiquitylates H2AK13,15ub and regulates DNA damage response. Genes Dev. 2016 Apr 15; 30 (8):946-59
    View PubMed
16. Xiong R, Wang Z, Zhao Z, Li H, Chen W, Zhang B, Wang L, Wu L, Li W, Ding J, Chen S. MicroRNA-494 reduces DJ-1 expression and exacerbates neurodegeneration. Neurobiol Aging. 2014 Mar; 35 (3):705-14 Epub 2013 Oct 23
    View PubMed
17. Han J, Zhang H, Zhang H, Wang Z, Zhou H, Zhang Z. A Cul4 E3 ubiquitin ligase regulates histone hand-off during nucleosome assembly. Cell. 2013 Nov 7; 155 (4):817-29
    View PubMed
18. Zhang H, Wang Z, Zhang Z. PP1alpha, PP1beta and Wip-1 regulate H4S47 phosphorylation and deposition of histone H3 variant H3.3. Nucleic Acids Res. 2013 Sep; 41 (17):8085-93 Epub 2013 July 04
    View PubMed
19. Zhi-Kun S, Hong-Qi Y, Zhi-Quan W, Jing P, Zhen H, Sheng-Di C. Erythropoietin prevents PC12 cells from beta-amyloid-induced apoptosis via PI3KAkt pathway. Transl Neurodegener. 2012 Feb 29; 1 (1):7
    View PubMed
20. Wang Z, Liu J, Chen S, Wang Y, Cao L, Zhang Y, Kang W, Li H, Gui Y, Chen S, Ding J. DJ-1 modulates the expression of Cu/Zn-superoxide dismutase-1 through the Erk1/2-Elk1 pathway in neuroprotection. Ann Neurol. 2011 Oct; 70 (4):591-9 Epub 2011 July 27
    View PubMed
21. Wang Z, Zhang Y, Zhang S, Guo Q, Tan Y, Wang X, Xiong R, Ding J, Chen S. DJ-1 can inhibit microtubule associated protein 1 B formed aggregates. Mol Neurodegener. 2011 Jun 6; 6:38 Epub 2011 June 06
    View PubMed
22. Zhang Y, Deng YL, Ma JF, Zheng L, Hong Z, Wang ZQ, Sheng CY, Xiao Q, Cao L, Chen SD. Transthyretin-related hereditary amyloidosis in a Chinese family with TTR Y114C mutation. Neurodegener Dis. 2011; 8 (4):187-93 Epub 2010 Dec 03
    View PubMed
23. Li QY, Wang HM, Wang ZQ, Ma JF, Ding JQ, Chen SD. Salidroside attenuates hypoxia-induced abnormal processing of amyloid precursor protein by decreasing BACE1 expression in SH-SY5Y cells. Neurosci Lett. 2010 Sep 13; 481 (3):154-8 Epub 2010 July 03
    View PubMed
24. Zhou HY, Tan YY, Wang ZQ, Wang G, Lu GQ, Chen SD. Proteasome inhibitor lactacystin induces cholinergic degeneration. Can J Neurol Sci. 2010 Mar; 37 (2):229-34
    View PubMed
25. Wang H, Ma J, Tan Y, Wang Z, Sheng C, Chen S, Ding J. Amyloid-beta1-42 induces reactive oxygen species-mediated autophagic cell death in U87 and SH-SY5Y cells. J Alzheimers Dis. 2010; 21 (2):597-610
    View PubMed
26. Hong Z, Zhang QY, Liu J, Wang ZQ, Zhang Y, Xiao Q, Lu J, Zhou HY, Chen SD. Phosphoproteome study reveals Hsp27 as a novel signaling molecule involved in GDNF-induced neurite outgrowth. J Proteome Res. 2009 Jun; 8 (6):2768-87
    View PubMed
27. Tan YY, Zhou HY, Wang ZQ, Chen SD. Endoplasmic reticulum stress contributes to the cell death induced by UCH-L1 inhibitor. Mol Cell Biochem. 2008 Nov; 318 (1-2):109-15 Epub 2008 July 12
    View PubMed
28. Sun ZK, Yang HQ, Pan J, Zhen H, Wang ZQ, Chen SD, Ding JQ. Protective effects of erythropoietin on tau phosphorylation induced by beta-amyloid. J Neurosci Res. 2008 Oct; 86 (13):3018-27
    View PubMed
29. Wang G, Zeng J, Shen CY, Wang ZQ, Chen SD. Overexpression of Kir2.3 in PC12 cells resists rotenone-induced neurotoxicity associated with PKC signaling pathway. Biochem Biophys Res Commun. 2008 Sep 19; 374 (2):204-9 Epub 2008 July 11
    View PubMed
30. Pan J, Zhao YX, Wang ZQ, Jin L, Sun ZK, Chen SD. Expression of FasL and its interaction with Fas are mediated by c-Jun N-terminal kinase (JNK) pathway in 6-OHDA-induced rat model of Parkinson disease. Neurosci Lett. 2007 Nov 27; 428 (2-3):82-7 Epub 2007 Sept 25
    View PubMed
31. Wang ZQ, Zhou HY, Chen SD. The role of DJ-1 in the pathogenesis of Parkinson's disease. Neurosci Bull. 2006 Jul; 22 (4):232-4
    View PubMed