Publications

1. Dilger OB, Carstens MF, Bothun CE, Payne AN, Berry DJ, Sanchez-Sotelo J, Morrey ME, Thaler R, Dudakovic A, Abdel MP. Induction of cellular autophagy impairs TGF-beta1-mediated extracellular matrix deposition in primary human knee fibroblasts. Bone Joint Res. 2025 Apr 7; 14 (4):328-337 Epub 2025 Apr 07
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2. Alder KD, Carstens MF, Bothun CE, Dilger OB, Payne AN, Thaler R, Morrey ME, Sanchez-Sotelo J, Berry DJ, Dudakovic A, Abdel MP. An Abbreviated Rabbit Knee Model of Joint Contracture. Tissue Eng Part C Methods. 2025 Apr; 31 (4):145-152
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3. Carstens MF, Alder KD, Dilger OB, Bothun CE, Payne AN, Thaler R, Morrey ME, Sanchez-Sotelo J, Berry DJ, Dudakovic A, Abdel MP. Effect of Antiseptic Irrigation Solutions on Primary Human Knee Fibroblasts Cultured in Human Platelet Lysate. J Arthroplasty. 2025 Jan 19 [Epub ahead of print]
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4. Eirin A, Thaler R, Glasstetter LM, Xing L, Zhu XY, Osborne AC, Mondesir R, Bhagwate AV, Lerman A, van Wijnen AJ, Lerman LO. Obesity-driven mitochondrial dysfunction in human adipose tissue-derived mesenchymal stem/stromal cells involves epigenetic changes. Cell Death Dis. 2024 Jun 1; 15 (6):387 Epub 2024 June 01
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5. Dudakovic A, Limberg AK, Bothun CE, Dilger OB, Bayram B, Bettencourt JW, Salmons HI, Thaler R, Karczewski DC, Owen AR, Iyer VG, Payne AN, Carstens MF, van Wijnen AJ, Berry DJ, Sanchez-Sotelo J, Morrey ME, Abdel MP. AdipoRon reduces TGFbeta1-mediated collagen deposition in vitro and alleviates knee stiffness in vivo. J Cell Physiol. 2024 Feb; 239 (2):e31168 Epub 2023 Dec 27
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6. Dashti P, Thaler R, Hawse JR, Galvan ML, van der Eerden BJ, van Wijnen AJ, Dudakovic A. G-protein coupled receptor 5C (GPRC5C) is required for osteoblast differentiation and responds to EZH2 inhibition and multiple osteogenic signals. Bone. 2023 Nov; 176:116866 Epub 2023 Aug 07
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7. Blouin S, Khani F, Messmer P, Roschger P, Hartmann MA, van Wijnen AJ, Thaler R, Misof BM. Vitamin C Deficiency Deteriorates Bone Microarchitecture and Mineralization in a Sex-Specific Manner in Adult Mice. J Bone Miner Res. 2023 Oct; 38 (10):1509-1520 Epub 2023 Aug 08
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8. Carrasco ME, Thaler R, Nardocci G, Dudakovic A, van Wijnen AJ. Inhibition of Ezh2 redistributes bivalent domains within transcriptional regulators associated with WNT and Hedgehog pathways in osteoblasts. J Biol Chem. 2023 Sep; 299 (9):105155 Epub 2023 Aug 11
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9. Thaler R, Yoshizaki K, Nguyen T, Fukumoto S, Den Besten P, Bikle DD, Oda Y. Mediator 1 ablation induces enamel-to-hair lineage conversion in mice through enhancer dynamics. Commun Biol. 2023 Jul 21; 6 (1):766 Epub 2023 July 21
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10. Glasstetter LM, Oderinde TS, Mirchandani M, Rajagopalan KS, Barsom SH, Thaler R, Siddiqi S, Zhu XY, Tang H, Jordan KL, Saadiq IM, van Wijnen AJ, Eirin A, Lerman LO. Obesity and dyslipidemia are associated with partially reversible modifications to DNA hydroxymethylation of apoptosis- and senescence-related genes in swine adipose-derived mesenchymal stem/stromal cells. Stem Cell Res Ther. 2023 May 25; 14 (1):143
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11. Dudakovic A, Bayram B, Bettencourt JW, Limberg AK, Galvan ML, Carrasco ME, Stans B, Thaler R, Morrey ME, Sanchez-Sotelo J, Berry DJ, van Wijnen AJ, Abdel MP. The epigenetic regulator BRD4 is required for myofibroblast differentiation of knee fibroblasts. J Cell Biochem. 2023 Feb; 124 (2):320-334 Epub 2023 Jan 17
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12. Dashti P, van de Peppel J, Thaler R, Paradise CR, Stein GS, Montecino MA, van Leeuwen JPTM, van der Eerden BJ, Dudakovic A, van Wijnen AJ. The lysine methyltransferases SET and MYND domain containing 2 (Smyd2) and Enhancer of Zeste 2 (Ezh2) co-regulate osteoblast proliferation and mineralization. Gene. 2023 Jan 30; 851:146928 Epub 2022 Sept 30
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13. Farooqui N, Mohan A, Isik B, Goksu BB, Thaler R, Zhu XY, Krier JD, Saadiq IM, Ferguson CM, Jordan KL, Tang H, Textor SC, Hickson TJ, van Wijnen AJ, Eirin A, Lerman LO, Herrmann SM. Effect of Hypoxia Preconditioning on the Regenerative Capacity of Adipose Tissue Derived Mesenchymal Stem Cells in a Model of Renal Artery Stenosis. Stem Cells. 2023 Jan 30; 41(1):50-63.
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14. Thaler R, Khani F, Sturmlechner I, Dehghani SS, Denbeigh JM, Zhou X, Pichurin O, Dudakovic A, Jerez SS, Zhong J, Lee JH, Natarajan R, Kalajzic I, Jiang YH, Deyle DR, Paschalis EP, Misof BM, Ordog T, van Wijnen AJ. Vitamin C epigenetically controls osteogenesis and bone mineralization. Nat Commun. 2022 Oct 6; 13 (1):5883 Epub 2022 Oct 06
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15. Dudakovic A, Jerez S, Deosthale PJ, Denbeigh JM, Paradise CR, Gluscevic M, Zan P, Begun DL, Camilleri ET, Pichurin O, Khani F, Thaler R, Lian JB, Stein GS, Westendorf JJ, Plotkin LI, van Wijnen AJ. MicroRNA-101a enhances trabecular bone accrual in male mice. Sci Rep. 2022 Aug 3; 12 (1):13361 Epub 2022 Aug 03
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16. Rajagopalan KS, Glasstetter LM, Zhu XY, Thaler R, Tang H, Jordan KL, Saadiq IM, Herrmann SM, Chade AR, Irazabal MV, Lerman LO, Eirin A. Renal Ischemia Induces Epigenetic Changes in Apoptotic, Proteolytic, and Mitochondrial Genes in Swine Scattered Tubular-like Cells. Cells. 2022 May 31; 11 (11)
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17. Bayram B, Thaler R, Bettencourt JW, Limberg AK, Sheehan KP, Owen AR, Berry DJ, Morrey ME, Sanchez-Sotelo J, van Wijnen AJ, Dudakovic A, Abdel MP. Human outgrowth knee fibroblasts from patients undergoing total knee arthroplasty exhibit a unique gene expression profile and undergo myofibroblastogenesis upon TGFbeta1 stimulation. J Cell Biochem. 2022 May; 123 (5):878-892 Epub 2022 Feb 28
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18. Trousdale WH, Limberg AK, Reina N, Salib CG, Thaler R, Dudakovic A, Berry DJ, Morrey ME, Sanchez-Sotelo J, van Wijnen A, Abdel MP. Intra-articular celecoxib improves knee extension regardless of surgical release in a rabbit model of arthrofibrosis. Bone Joint Res. 2022 Jan; 11 (1):32-39
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19. Paradise CR, Galvan ML, Pichurin O, Jerez S, Kubrova E, Dehghani SS, Carrasco ME, Thaler R, Larson AN, van Wijnen AJ, Dudakovic A. Brd4 is required for chondrocyte differentiation and endochondral ossification. Bone. 2022 Jan; 154:116234 Epub 2021 Oct 23
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20. Lewallen EA, Trousdale WH, Thaler R, Yao JJ, Xu W, Denbeigh JM, Nair A, Kocher JP, Dudakovic A, Berry DJ, Cohen RC, Abdel MP, Lewallen DG, van Wijnen AJ. Surface Roughness of Titanium Orthopedic Implants Alters the Biological Phenotype of Human Mesenchymal Stromal Cells. Tissue Eng Part A. 2021 Dec; 27 (23-24):1503-1516 Epub 2021 Aug 16
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21. Paradise CR, De La Vega RE, Galvan ML, Carrasco ME, Thaler R, van Wijnen AJ, Dudakovic A. Brd4 Inactivation Increases Adenoviral Delivery of BMP2 for Paracrine Stimulation of Osteogenic Differentiation as a Gene Therapeutic Concept to Enhance Bone Healing. JBMR Plus. 2021 Oct; 5 (10):e10520 Epub 2021 June 23
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22. Galvan ML, Paradise CR, Kubrova E, Jerez S, Khani F, Thaler R, Dudakovic A, van Wijnen AJ. Multiple pharmacological inhibitors targeting the epigenetic suppressor enhancer of zeste homolog 2 (Ezh2) accelerate osteoblast differentiation. Bone. 2021 Sep; 150:115993 Epub 2021 Apr 30
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23. Mathot F, Rbia N, Thaler R, Dietz AB, van Wijnen AJ, Bishop AT, Shin AY. Gene expression profiles of human adipose-derived mesenchymal stem cells dynamically seeded on clinically available processed nerve allografts and collagen nerve guides. Neural Regen Res. 2021 Aug; 16 (8):1613-1621
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24. Saffari TM, Mathot F, Thaler R, van Wijnen AJ, Bishop AT, Shin AY. Microcomputed analysis of nerve angioarchitecture after combined stem cell delivery and surgical angiogenesis to nerve allograft. J Plast Reconstr Aesthet Surg. 2021 Aug; 74 (8):1919-1930 Epub 2020 Dec 24
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25. Afarideh M, Thaler R, Khani F, Tang H, Jordan KL, Conley SM, Saadiq IM, Obeidat Y, Pawar AS, Eirin A, Zhu XY, Lerman A, van Wijnen AJ, Lerman LO. Global epigenetic alterations of mesenchymal stem cells in obesity: the role of vitamin C reprogramming. Epigenetics. 2021 Jun-Jul; 16 (7):705-717 Epub 2020 Sept 20
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26. Isik B, Thaler R, Goksu BB, Conley SM, Al-Khafaji H, Mohan A, Afarideh M, Abumoawad AM, Zhu XY, Krier JD, Saadiq IM, Tang H, Eirin A, Hickson LJ, van Wijnen AJ, Textor SC, Lerman LO, Herrmann SM. Hypoxic preconditioning induces epigenetic changes and modifies swine mesenchymal stem cell angiogenesis and senescence in experimental atherosclerotic renal artery stenosis. Stem Cell Res Ther. 2021 Apr 14; 12(1):240.
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27. van Wijnen AJ, Bagheri L, Badreldin AA, Larson AN, Dudakovic A, Thaler R, Paradise CR, Wu Z. Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development. Bone. 2021 Feb; 143:115659 Epub 2020 Sept 24
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28. Davis JL, Thaler R, Cox L, Ricci B, Zannit HM, Wan F, Faccio R, Dudakovic A, van Wijnen AJ, Veis DJ. Constitutive activation of NF-kappaB inducing kinase (NIK) in the mesenchymal lineage using Osterix (Sp7)- or Fibroblast-specific protein 1 (S100a4)-Cre drives spontaneous soft tissue sarcoma. PLoS One. 2021; 16 (7):e0254426 Epub 2021 July 22
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29. Houben RH, Thaler R, Friedrich PF, Shin AY, van Wijnen AJ, Bishop AT. Autogenous Arteriovenous Bundle Implantation Maintains Viability Without Increased Immune Response in Large Porcine Bone Allotransplants. Transplant Proc. 2021 Jan-Feb; 53 (1):417-426 Epub 2020 Sept 18
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30. Mathot F, Rbia N, Thaler R, Bishop AT, van Wijnen AJ, Shin AY. Introducing human adipose-derived mesenchymal stem cells to Avance() nerve grafts and NeuraGen() nerve guides. J Plast Reconstr Aesthet Surg. 2020 Aug; 73 (8):1473-1481 Epub 2020 Apr 11
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31. Bayram B, Limberg AK, Salib CG, Bettencourt JW, Trousdale WH, Lewallen EA, Reina N, Paradise CR, Thaler R, Morrey ME, Sanchez-Sotelo J, Berry DJ, van Wijnen AJ, Abdel MP. Molecular pathology of human knee arthrofibrosis defined by RNA sequencing. Genomics. 2020 Jul; 112 (4):2703-2712 Epub 2020 Mar 05
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32. Yao JJ, Lewallen EA, Thaler R, Dudakovic A, Wermers M, Day P, Eckdahl S, Jannetto P, Bornhorst JA, Larson AN, Abdel MP, Lewallen DG, van Wijnen AJ. Challenges in the Measurement and Interpretation of Serum Titanium Concentrations. Biol Trace Elem Res. 2020 Jul; 196 (1):20-26 Epub 2019 Nov 06
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33. Dudakovic A, Samsonraj RM, Paradise CR, Galeano-Garces C, Mol MO, Galeano-Garces D, Zan P, Galvan ML, Hevesi M, Pichurin O, Thaler R, Begun DL, Kloen P, Karperien M, Larson AN, Westendorf JJ, Cool SM, van Wijnen AJ. Inhibition of the epigenetic suppressor EZH2 primes osteogenic differentiation mediated by BMP2. J Biol Chem. 2020 Jun 5; 295 (23):7877-7893 Epub 2020 Apr 24
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34. Paradise CR, Galvan ML, Kubrova E, Bowden S, Liu E, Carstens MF, Thaler R, Stein GS, van Wijnen AJ, Dudakovic A. The epigenetic reader Brd4 is required for osteoblast differentiation. J Cell Physiol. 2020 Jun; 235 (6):5293-5304 Epub 2019 Dec 23
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35. Houben RH, Thaler R, Kotsougiani D, Friedrich PF, Shin AY, van Wijnen AJ, Bishop AT. Neo-Angiogenesis, Transplant Viability, and Molecular Analyses of Vascularized Bone Allotransplantation Surgery in a Large Animal Model. J Orthop Res. 2020 Feb; 38 (2):288-296 Epub 2019 Oct 06
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36. Mathot F, Rbia N, Thaler R, Bishop AT, Van Wijnen AJ, Shin AY. Gene expression profiles of differentiated and undifferentiated adipose derived mesenchymal stem cells dynamically seeded onto a processed nerve allograft. Gene. 2020 Jan 15; 724:144151 Epub 2019 Oct 15
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37. Salib CG, Lewallen EA, Paradise CR, Tibbo ME, Robin JX, Trousdale WH, Morrey LM, Xiao J, Turner TW, Limberg AK, Jay AG, Thaler R, Dudakovic A, Sanchez-Sotelo J, Morrey ME, Berry DJ, Lewallen DG, van Wijnen AJ, Abdel MP. Molecular pathology of adverse local tissue reaction caused by metal-on-metal implants defined by RNA-seq. Genomics. 2019 Dec; 111 (6):1404-1411 Epub 2018 Sept 21
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38. Soreide E, Denbeigh JM, Lewallen EA, Thaler R, Samsonraj RM, Jones DL, Xu W, Larson D, Nordsletten L, Kakar S, van Wijnen AJ. A multi-chamber tissue culture device for load-dependent parallel evaluation of tendon explants. BMC Musculoskelet Disord. 2019 Nov 18; 20 (1):549
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39. Soreide E, Denbeigh JM, Lewallen EA, Thaler R, Xu W, Berglund L, Yao JJ, Martinez A, Nordsletten L, van Wijnen AJ, Kakar S. In vivo assessment of high-molecular-weight polyethylene core suture tape for intra-articular ligament reconstruction: an animal study. Bone Joint J. 2019 Oct; 101-B (10):1238-1247
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40. Jerez S, Araya H, Hevia D, Irarrazaval CE, Thaler R, van Wijnen AJ, Galindo M. Extracellular vesicles from osteosarcoma cell lines contain miRNAs associated with cell adhesion and apoptosis. Gene. 2019 Aug 20; 710:246-257 Epub 2019 June 06
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41. Villanueva F, Araya H, Briceno P, Varela N, Stevenson A, Jerez S, Tempio F, Chnaiderman J, Perez C, Villarroel M, Concha E, Khani F, Thaler R, Salazar-Onfray F, Stein GS, van Wijnen AJ, Galindo M. The cancer-related transcription factor RUNX2 modulates expression and secretion of the matricellular protein osteopontin in osteosarcoma cells to promote adhesion to endothelial pulmonary cells and lung metastasis. J Cell Physiol. 2019 Aug; 234 (8):13659-13679 Epub 2019 Jan 13
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42. Rbia N, Bulstra LF, Thaler R, Hovius SER, van Wijnen AJ, Shin AY. In Vivo Survival of Mesenchymal Stromal Cell-Enhanced Decellularized Nerve Grafts for Segmental Peripheral Nerve Reconstruction. J Hand Surg Am. 2019 Jun; 44 (6):514.e1-514.e11 Epub 2018 Oct 06
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43. Araya HF, Sepulveda H, Lizama CO, Vega OA, Jerez S, Briceno PF, Thaler R, Riester SM, Antonelli M, Salazar-Onfray F, Rodriguez JP, Moreno RD, Montecino M, Charbonneau M, Dubois CM, Stein GS, van Wijnen AJ, Galindo MA. Expression of the ectodomain-releasing protease ADAM17 is directly regulated by the osteosarcoma and bone-related transcription factor RUNX2. J Cell Biochem. 2018 Nov; 119 (10):8204-8219 Epub 2018 June 19
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44. Dudakovic A, Camilleri ET, Paradise CR, Samsonraj RM, Gluscevic M, Paggi CA, Begun DL, Khani F, Pichurin O, Ahmed FS, Elsayed R, Elsalanty M, McGee-Lawrence ME, Karperien M, Riester SM, Thaler R, Westendorf JJ, van Wijnen AJ. Enhancer of zeste homolog 2 (Ezh2) controls bone formation and cell cycle progression during osteogenesis in mice. J Biol Chem. 2018 Aug 17; 293 (33):12894-12907 Epub 2018 June 13
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45. Vega OA, Lucero CMJ, Araya HF, Jerez S, Tapia JC, Antonelli M, Salazar-Onfray F, Las Heras F, Thaler R, Riester SM, Stein GS, van Wijnen AJ, Galindo MA. Wnt/beta-Catenin Signaling Activates Expression of the Bone-Related Transcription Factor RUNX2 in Select Human Osteosarcoma Cell Types. J Cell Biochem. 2017 Nov; 118 (11):3662-3674 Epub 2017 May 18
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46. Karlic H, Haider F, Thaler R, Spitzer S, Klaushofer K, Varga F. Statin and Bisphosphonate Induce Starvation in Fast-Growing Cancer Cell Lines. Int J Mol Sci. 2017 Sep 15; 18(9).
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47. Pollock K, Samsonraj RM, Dudakovic A, Thaler R, Stumbras A, McKenna DH, Dosa PI, van Wijnen AJ, Hubel A. Improved Post-Thaw Function and Epigenetic Changes in Mesenchymal Stromal Cells Cryopreserved Using Multicomponent Osmolyte Solutions. Stem Cells Dev. 2017 Jun 1; 26 (11):828-842 Epub 2017 Mar 15
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48. Khani F, Thaler R, Paradise CR, Deyle DR, Kruijthof-de Julio M, Galindo M, Gordon JA, Stein GS, Dudakovic A, van Wijnen AJ. Histone H4 Methyltransferase Suv420h2 Maintains Fidelity of Osteoblast Differentiation. J Cell Biochem. 2017 May; 118 (5):1262-1272 Epub 2016 Nov 30
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49. Riester SM, Torres-Mora J, Dudakovic A, Camilleri ET, Wang W, Xu F, Thaler RR, Evans JM, Zwartbol R, Briaire-de Bruijn IH, Maran A, Folpe AL, Inwards CY, Rose PS, Shives TC, Yaszemski MJ, Sim FH, Deyle DR, Larson AN, Galindo MA, Cleven AGH, Oliveira AM, Cleton-Jansen AM, Bovee JVMG, van Wijnen AJ. Hypoxia-related microRNA-210 is a diagnostic marker for discriminating osteoblastoma and osteosarcoma. J Orthop Res. 2017 May; 35 (5):1137-1146 Epub 2016 June 28
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50. Dudakovic A, Gluscevic M, Paradise CR, Dudakovic H, Khani F, Thaler R, Ahmed FS, Li X, Dietz AB, Stein GS, Montecino MA, Deyle DR, Westendorf JJ, van Wijnen AJ. Profiling of human epigenetic regulators using a semi-automated real-time qPCR platform validated by next generation sequencing. Gene. 2017 Apr 20; 609:28-37. Epub 2017 Jan 27.
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51. Jerez S, Araya H, Thaler R, Charlesworth MC, Lopez-Solis R, Kalergis AM, Cespedes PF, Dudakovic A, Stein GS, van Wijnen AJ, Galindo M. Proteomic Analysis of Exosomes and Exosome-Free Conditioned Media From Human Osteosarcoma Cell Lines Reveals Secretion of Proteins Related to Tumor Progression. J Cell Biochem. 2017 Feb; 118 (2):351-360 Epub 2016 Aug 15
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52. Jerez S, Araya H, Thaler R, Charlesworth MC, Lopez-Solis R, Kalergis AM, Cespedes PF, Dudakovic A, Stein GS, van Wijnen AJ, Galindo M. Proteomic analysis of exosomes and exosome-free conditioned media from human osteosarcoma cell lines reveals secretion of proteins related to tumor progression Journal of Cellular Biochemistry. 2017; 118: (2)351-60.
    
53. Yao JJ, Lewallen EA, Trousdale WH, Xu W, Thaler R, Salib CG, Reina N, Abdel MP, Lewallen DG, van Wijnen AJ. Local Cellular Responses to Titanium Dioxide from Orthopedic Implants. Biores Open Access. 2017; 6 (1):94-103 Epub 2017 July 01
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54. Dudakovic A, Camilleri ET, Riester SM, Paradise CR, Gluscevic M, O'Toole TM, Thaler R, Evans JM, Yan H, Subramaniam M, Hawse JR, Stein GS, Montecino MA, McGee-Lawrence ME, Westendorf JJ, van Wijnen AJ. Enhancer of Zeste Homolog 2 Inhibition Stimulates Bone Formation and Mitigates Bone Loss Caused by Ovariectomy in Skeletally Mature Mice. J Biol Chem. 2016 Nov 18; 291 (47):24594-24606 Epub 2016 Oct 10
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55. Lewallen EA, Jones DL, Dudakovic A, Thaler R, Paradise CR, Kremers HM, Abdel MP, Kakar S, Dietz AB, Cohen RC, Lewallen DG, van Wijnen AJ. Osteogenic potential of human adipose-tissue-derived mesenchymal stromal cells cultured on 3D-printed porous structured titanium. Gene. 2016 May 1; 581 (2):95-106 Epub 2016 Jan 13
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56. Varela N, Aranguiz A, Lizama C, Sepulveda H, Antonelli M, Thaler R, Moreno RD, Montecino M, Stein GS, van Wijnen AJ, Galindo M. Mitotic Inheritance of mRNA Facilitates Translational Activation of the Osteogenic-Lineage Commitment Factor Runx2 in Progeny of Osteoblastic Cells. J Cell Physiol. 2016 May; 231 (5):1001-14 Epub 2015 Sept 18
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57. Thaler R, Maurizi A, Roschger P, Sturmlechner I, Khani F, Spitzer S, Rumpler M, Zwerina J, Karlic H, Dudakovic A, Klaushofer K, Teti A, Rucci N, Varga F, van Wijnen AJ. Anabolic and Antiresorptive Modulation of Bone Homeostasis by the Epigenetic Modulator Sulforaphane, a Naturally Occurring Isothiocyanate. J Biol Chem. 2016 Mar 25; 291(13):6754-71. Epub 2016 Jan 12.
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58. Getzlaf MA, Lewallen EA, Kremers HM, Jones DL, Bonin CA, Dudakovic A, Thaler R, Cohen RC, Lewallen DG, van Wijnen AJ. Multi-disciplinary antimicrobial strategies for improving orthopaedic implants to prevent prosthetic joint infections in hip and knee. J Orthop Res. 2016 Feb; 34 (2):177-86 Epub 2015 Dec 29
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59. Dudakovic A, Camilleri ET, Xu F, Riester SM, McGee-Lawrence ME, Bradley EW, Paradise CR, Lewallen EA, Thaler R, Deyle DR, Larson AN, Lewallen DG, Dietz AB, Stein GS, Montecino MA, Westendorf JJ, van Wijnen AJ. Epigenetic Control of Skeletal Development by the Histone Methyltransferase Ezh2. J Biol Chem. 2015 Nov 13; 290 (46):27604-17 Epub 2015 Sept 30
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60. Lenertz LY, Baughman CJ, Waldschmidt NV, Thaler R, van Wijnen AJ. Control of bone development by P2X and P2Y receptors expressed in mesenchymal and hematopoietic cells. Gene. 2015 Oct 1; 570 (1):1-7 Epub 2015 June 14
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61. Karlic H, Thaler R, Gerner C, Grunt T, Proestling K, Haider F, Varga F. Inhibition of the mevalonate pathway affects epigenetic regulation in cancer cells. Cancer Genet. 2015 May; 208(5):241-52. Epub 2015 Mar 18.
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62. Thaler R, Sturmlechner I, Spitzer S, Riester SM, Rumpler M, Zwerina J, Klaushofer K, van Wijnen AJ, Varga F. Acute-phase protein serum amyloid A3 is a novel paracrine coupling factor that controls bone homeostasis. FASEB J. 2015 Apr; 29(4):1344-59. Epub 2014 Dec 09.
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63. Karlic H, Herrmann H, Varga F, Thaler R, Reitermaier R, Spitzer S, Ghanim V, Blatt K, Sperr WR, Valent P, Pfeilstocker M. The role of epigenetics in the regulation of apoptosis in myelodysplastic syndromes and acute myeloid leukemia. Crit Rev Oncol Hematol. 2014 Apr; 90 (1):1-16 Epub 2013 Oct 12
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64. Thaler R, Zwerina J, Rumpler M, Spitzer S, Gamsjaeger S, Paschalis EP, Klaushofer K, Varga F. Homocysteine induces serum amyloid A3 in osteoblasts via unlocking RGD-motifs in collagen. FASEB J. 2013 Feb; 27 (2):446-63 Epub 2012 Oct 19
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65. Thaler R, Spitzer S, Karlic H, Berger C, Klaushofer K, Varga F. Ibandronate increases the expression of the pro-apoptotic gene FAS by epigenetic mechanisms in tumor cells. Biochem Pharmacol. 2013 Jan 15; 85 (2):173-85 Epub 2012 Oct 24
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66. Thaler R, Spitzer S, Karlic H, Klaushofer K, Varga F. DMSO is a strong inducer of DNA hydroxymethylation in pre-osteoblastic MC3T3-E1 cells. Epigenetics. 2012 Jun 1; 7 (6):635-51 Epub 2012 June 01
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67. Thaler R, Rumpler M, Spitzer S, Klaushofer K, Varga F. Mospd1, a new player in mesenchymal versus epidermal cell differentiation. J Cell Physiol. 2011 Oct; 226 (10):2505-15
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68. Thaler R, Agsten M, Spitzer S, Paschalis EP, Karlic H, Klaushofer K, Varga F. Homocysteine suppresses the expression of the collagen cross-linker lysyl oxidase involving IL-6, Fli1, and epigenetic DNA methylation. J Biol Chem. 2011 Feb 18; 286 (7):5578-88 Epub 2010 Dec 09
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69. Varga F, Rumpler M, Zoehrer R, Turecek C, Spitzer S, Thaler R, Paschalis EP, Klaushofer K. T3 affects expression of collagen I and collagen cross-linking in bone cell cultures. Biochem Biophys Res Commun. 2010 Nov 12; 402 (2):180-5 Epub 2010 Aug 11
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70. Thaler R, Karlic H, Spitzer S, Klaushofer K, Varga F. Extra-cellular matrix suppresses expression of the apoptosis mediator Fas by epigenetic DNA methylation. Apoptosis. 2010 Jun; 15 (6):728-37
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71. Thaler R, Spitzer S, Rumpler M, Fratzl-Zelman N, Klaushofer K, Paschalis EP, Varga F. Differential effects of homocysteine and beta aminopropionitrile on preosteoblastic MC3T3-E1 cells. Bone. 2010 Mar; 46 (3):703-9 Epub 2009 Nov 04
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72. Thaler R, Karlic H, Rust P, Haslberger AG. Epigenetic regulation of human buccal mucosa mitochondrial superoxide dismutase gene expression by diet. Br J Nutr. 2009 Mar; 101 (5):743-9 Epub 2008 Aug 07
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73. Liszt K, Zwielehner J, Handschur M, Hippe B, Thaler R, Haslberger AG. Characterization of bacteria, clostridia and Bacteroides in faeces of vegetarians using qPCR and PCR-DGGE fingerprinting. Ann Nutr Metab. 2009; 54 (4):253-7 Epub 2009 July 27
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