Publications

1. Liu Q, Pepin RM, Novak MK, Maschhoff KR, Worner K, Hu W. AGO1 controls protein folding in mouse embryonic stem cell fate decisions. Dev Cell. 2024 Apr 22; 59 (8):979-990.e5 Epub 2024 Mar 07
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2. Worner K, Liu Q, Maschhoff KR, Hu W. Identification of RNA-binding proteins' direct effects on gene expression via the degradation tag system. RNA. 2023 Oct; 29 (10):1453-1457 Epub 2023 July 06
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3. Liu Q, Novak MK, Pepin RM, Maschhoff KR, Worner K, Chen X, Zhang S, Hu W. A congenital hydrocephalus-causing mutation in Trim71 induces stem cell defects via inhibiting Lsd1 mRNA translation. EMBO Rep. 2023 Feb 6; 24 (2):e55843 Epub 2022 Dec 27
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4. Liu Q, Novak MK, Pepin RM, Maschhoff KR, Hu W. Different congenital hydrocephalus-associated mutations in Trim71 impair stem cell differentiation via distinct gain-of-function mechanisms. PLoS Biol. 2023 Feb; 21 (2):e3001947 Epub 2023 Feb 09
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5. Liu Q, Novak MK, Pepin RM, Eich T, Hu W. microRNA-mediated regulation of microRNA machinery controls cell fate decisions. Elife. 2021 Oct 1; 10 Epub 2021 Oct 01
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6. Assabban A, Dubois-Vedrenne I, Van Maele L, Salcedo R, Snyder BL, Zhou L, Azouz A, de Toeuf B, Lapouge G, La C, Melchior M, Nguyen M, Thomas S, Wu SF, Hu W, Kruys V, Blanpain C, Trinchieri G, Gueydan C, Blackshear PJ, Goriely S. Tristetraprolin expression by keratinocytes protects against skin carcinogenesis. JCI Insight. 2021 Mar 8; 6 (5) Epub 2021 Mar 08
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7. Liu Q, Chen X, Novak MK, Zhang S, Hu W. Repressing Ago2 mRNA translation by Trim71 maintains pluripotency through inhibiting let-7 microRNAs. Elife. 2021 Feb 18; 10
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8. La C, de Toeuf B, Bindels LB, Van Maele L, Assabban A, Melchior M, Smout J, Kohler A, Nguyen M, Thomas S, Soin R, Delacourt N, Li H, Hu W, Blackshear PJ, Kruys V, Gueydan C, Oldenhove G, Goriely S. The RNA-binding protein tristetraprolin regulates RALDH2 expression by intestinal dendritic cells and controls local Treg homeostasis. Mucosal Immunol. 2021 Jan; 14 (1):80-91 Epub 2020 May 28
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9. Chen X, Castro SA, Liu Q, Hu W, Zhang S. Practical considerations on performing and analyzing CLIP-seq experiments to identify transcriptomic-wide RNA-protein interactions. Methods. 2019 Feb 15; 155:49-57 Epub 2018 Dec 06
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10. Hussain S, Bedekovics T, Liu Q, Hu W, Jeon H, Johnson SH, Vasmatzis G, May DG, Roux KJ, Galardy PJ. UCH-L1 bypasses mTOR to promote protein biosynthesis and is required for MYC-driven lymphomagenesis in mice. Blood. 2018 Dec 13; 132 (24):2564-2574 Epub 2018 Sept 26
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11. Zhang YJ, Gendron TF, Ebbert MTW, O'Raw AD, Yue M, Jansen-West K, Zhang X, Prudencio M, Chew J, Cook CN, Daughrity LM, Tong J, Song Y, Pickles SR, Castanedes-Casey M, Kurti A, Rademakers R, Oskarsson B, Dickson DW, Hu W, Gitler AD, Fryer JD, Petrucelli L. Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis. Nat Med. 2018 Aug; 24 (8):1136-1142 Epub 2018 June 25
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12. Zhang X, Chen X, Liu Q, Zhang S, Hu W. Translation repression via modulation of the cytoplasmic poly(A)-binding protein in the inflammatory response. Elife. 2017 Jun 21; 6 Epub 2017 June 21
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13. Alvarez-Dominguez JR, Zhang X, Hu W. Widespread and dynamic translational control of red blood cell development. Blood. 2017 Feb 2; 129 (5):619-629 Epub 2016 Nov 29
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14. Atianand MK, Hu W, Satpathy AT, Shen Y, Ricci EP, Alvarez-Dominguez JR, Bhatta A, Schattgen SA, McGowan JD, Blin J, Braun JE, Gandhi P, Moore MJ, Chang HY, Lodish HF, Caffrey DR, Fitzgerald KA. A Long Noncoding RNA lincRNA-EPS Acts as a Transcriptional Brake to Restrain Inflammation. Cell. 2016 Jun 16; 165: (7)1672-85.
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15. Zhang X, Hu W. Long noncoding RNAs in hematopoiesis. F1000Res. 2016; 5 Epub 2016 July 20
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16. Hu W, Yuan B, Lodish HF. Cpeb4-mediated translational regulatory circuitry controls terminal erythroid differentiation. Dev Cell. 2014 Sep 29; 30(6):660-72. Epub 2014 Sep 11.
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17. Smith JE, Alvarez-Dominguez JR, Kline N, Huynh NJ, Geisler S, Hu W, Coller J, Baker KE. Translation of small open reading frames within unannotated RNA transcripts in Saccharomyces cerevisiae. Cell Rep. 2014 Jun 26; 7(6):1858-66. Epub 2014 Jun 12.
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18. Alvarez-Dominguez JR, Hu W, Yuan B, Shi J, Park SS, Gromatzky AA, van Oudenaarden A, Lodish HF. Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation. Blood. 2014 Jan 23; 123(4):570-81. Epub 2013 Nov 07.
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19. Alvarez-Dominguez JR, Hu W, Gromatzky AA, Lodish HF. Long noncoding RNAs during normal and malignant hematopoiesis. Int J Hematol. 2014; 99(5):531-41. Epub 2014 Mar 09.
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20. Hu W, Coller J. Polysome analysis for determining mRNA and ribosome association in Saccharomyces cerevisiae. Methods Enzymol. 2013; 530:193-206.
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21. Hu W, Coller J. Method for measuring mRNA decay rate in Saccharomyces cerevisiae. Methods Enzymol. 2013; 530:137-55.
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22. Hu W, Alvarez-Dominguez JR, Lodish HF. Regulation of mammalian cell differentiation by long non-coding RNAs. EMBO Rep. 2012 Nov 6; 13(11):971-83. Epub 2012 Oct 16.
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23. Hu W, Coller J. What comes first: translational repression or mRNA degradation? The deepening mystery of microRNA function. Cell Res. 2012 Sep; 22(9):1322-4. Epub 2012 May 22.
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24. Hu W, Yuan B, Flygare J, Lodish HF. Long noncoding RNA-mediated anti-apoptotic activity in murine erythroid terminal differentiation. Genes Dev. 2011 Dec 15; 25(24):2573-8. Epub 2011 Dec 08.
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25. Hu W, Petzold C, Coller J, Baker KE. Nonsense-mediated mRNA decapping occurs on polyribosomes in Saccharomyces cerevisiae. Nat Struct Mol Biol. 2010 Feb; 17(2):244-7. Epub 2010 Jan 31.
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26. Co-translational mRNA decay in Saccharomyces cerevisiae. Nature. Hu W, Sweet TJ, Chamnongpol S, Baker KE, Coller J. 2009 Sep 10; 461(7261):225-9.
    
27. Sweet TJ, Boyer B, Hu W, Baker KE, Coller J. Microtubule disruption stimulates P-body formation. RNA. 2007 Apr; 13(4):493-502. Epub 2007 Feb 16.
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28. Hu W, Bai B, Hu Z, Chen Z, An X, Tang L, Yang J, Wang H, Wang H. Development and evaluation of a multitarget real-time Taqman reverse transcription-PCR assay for detection of the severe acute respiratory syndrome-associated coronavirus and surveillance for an apparently related coronavirus found in masked palm civets. J Clin Microbiol. 2005 May; 43 (5):2041-6
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29. Wang M, Hu W, Li Z, Lei W, Zhou J, Chen H, Wang H. .Genotypes investigation of Hepatitis B Virus in population in Xianning, Hubei Province Virologica Sinica. 2005; 20:447-49.