Publications

  1. Mullon PJ, Maldonado-Luevano E, Mehta KPM, Mohni KN. The herpes simplex virus alkaline nuclease is required to maintain replication fork progression. J Virol. 2024 Nov 7; e0183624 Epub 2024 Nov 07
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  2. Wessel SR, Mohni KN, Luzwick JW, Dungrawala H, Cortez D. Functional Analysis of the Replication Fork Proteome Identifies BET Proteins as PCNA Regulators. Cell Rep. 2019 Sep 24; 28 (13):3497-3509.e4
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  3. Thompson PS, Amidon KM, Mohni KN, Cortez D, Eichman BF. Protection of abasic sites during DNA replication by a stable thiazolidine protein-DNA cross-link. Nat Struct Mol Biol. 2019 Jul; 26 (7):613-618 Epub 2019 June 24
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  4. Mohni KN, Wessel SR, Zhao R, Wojciechowski AC, Luzwick JW, Layden H, Eichman BF, Thompson PS, Mehta KPM, Cortez D. HMCES Maintains Genome Integrity by Shielding Abasic Sites in Single-Strand DNA. Cell. 2019 Jan 10; 176 (1-2):144-153.e13 Epub 2018 Dec 13
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  5. Lou DI, Kim ET, Meyerson NR, Pancholi NJ, Mohni KN, Enard D, Petrov DA, Weller SK, Weitzman MD, Sawyer SL. An Intrinsically Disordered Region of the DNA Repair Protein Nbs1 Is a Species-Specific Barrier to Herpes Simplex Virus 1 in Primates. Cell Host Microbe. 2016 Aug 10; 20 (2):178-88
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  6. Kavanaugh G, Ye F, Mohni KN, Luzwick JW, Glick G, Cortez D. A whole genome RNAi screen identifies replication stress response genes. DNA Repair (Amst). 2015 Nov; 35:55-62 Epub 2015 Sept 26
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  7. Pozhidaeva AK, Mohni KN, Dhe-Paganon S, Arrowsmith CH, Weller SK, Korzhnev DM, Bezsonova I. Structural Characterization of Interaction between Human Ubiquitin-specific Protease 7 and Immediate-Early Protein ICP0 of Herpes Simplex Virus-1. J Biol Chem. 2015 Sep 18; 290 (38):22907-18 Epub 2015 July 29
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  8. Dungrawala H, Rose KL, Bhat KP, Mohni KN, Glick GG, Couch FB, Cortez D. The Replication Checkpoint Prevents Two Types of Fork Collapse without Regulating Replisome Stability. Mol Cell. 2015 Sep 17; 59 (6):998-1010 Epub 2015 Sept 10
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  9. Kavanaugh G, Zhao R, Guo Y, Mohni KN, Glick G, Lacy ME, Hutson MS, Ascano M, Cortez D. Enhancer of Rudimentary Homolog Affects the Replication Stress Response through Regulation of RNA Processing. Mol Cell Biol. 2015 Sep 1; 35 (17):2979-90 Epub 2015 June 22
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  10. Mohni KN, Thompson PS, Luzwick JW, Glick GG, Pendleton CS, Lehmann BD, Pietenpol JA, Cortez D. A Synthetic Lethal Screen Identifies DNA Repair Pathways that Sensitize Cancer Cells to Combined ATR Inhibition and Cisplatin Treatments. PLoS One. 2015; 10 (5):e0125482 Epub 2015 May 12
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  11. Smith S, Reuven N, Mohni KN, Schumacher AJ, Weller SK. Structure of the herpes simplex virus 1 genome: manipulation of nicks and gaps can abrogate infectivity and alter the cellular DNA damage response. J Virol. 2014 Sep 1; 88 (17):10146-56 Epub 2014 June 25
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  12. Mohni KN, Kavanaugh GM, Cortez D. ATR pathway inhibition is synthetically lethal in cancer cells with ERCC1 deficiency. Cancer Res. 2014 May 15; 74 (10):2835-45 Epub 2014 Mar 24
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  13. Ngunjiri JM, Buchek GM, Mohni KN, Sekellick MJ, Marcus PI. Influenza virus subpopulations: exchange of lethal H5N1 virus NS for H1N1 virus NS triggers de novo generation of defective-interfering particles and enhances interferon-inducing particle efficiency. J Interferon Cytokine Res. 2013 Mar; 33 (3):99-107 Epub 2012 Dec 10
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  14. Mohni KN, Dee AR, Smith S, Schumacher AJ, Weller SK. Efficient herpes simplex virus 1 replication requires cellular ATR pathway proteins. J Virol. 2013 Jan; 87 (1):531-42 Epub 2012 Oct 24
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  15. Mohni KN, Smith S, Dee AR, Schumacher AJ, Weller SK. Herpes simplex virus type 1 single strand DNA binding protein and helicase/primase complex disable cellular ATR signaling. PLoS Pathog. 2013; 9 (10):e1003652 Epub 2013 Oct 03
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  16. Schumacher AJ, Mohni KN, Kan Y, Hendrickson EA, Stark JM, Weller SK. The HSV-1 exonuclease, UL12, stimulates recombination by a single strand annealing mechanism. PLoS Pathog. 2012; 8 (8):e1002862 Epub 2012 Aug 09
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  17. Mohni KN, Mastrocola AS, Bai P, Weller SK, Heinen CD. DNA mismatch repair proteins are required for efficient herpes simplex virus 1 replication. J Virol. 2011 Dec; 85 (23):12241-53 Epub 2011 Sept 28
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  18. Mohni KN, Livingston CM, Cortez D, Weller SK. ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled. J Virol. 2010 Dec; 84 (23):12152-64 Epub 2010 Sept 22
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