Publications

1. Paganetti H, Simone CB 2nd, Bosch WR, Haas-Kogan D, Kirsch DG, Li H, Liang X, Liu W, Mahajan A, Story MD, Taylor PA, Willers H, Xiao Y, Buchsbaum JC. NRG Oncology White Paper on the Relative Biological Effectiveness in Proton Therapy. Int J Radiat Oncol Biol Phys. 2025 Jan 1; 121 (1):202-217 Epub 2024 July 25
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2. Ahmad R, Barcellini A, Baumann K, Benje M, Bender T, Bragado P, Charalampopoulou A, Chowdhury R, Davis AJ, Ebner DK, Eley J, Kloeber JA, Mutter RW, Friedrich T, Gutierrez-Uzquiza A, Helm A, Ibanez-Moragues M, Iturri L, Jansen J, Morcillo MA, Puerta D, Kokko AP, Sanchez-Parcerisa D, Scifoni E, Shimokawa T, Sokol O, Story MD, Thariat J, Tinganelli W, Tommasino F, Vandevoorde C, von Neubeck C. Particle Beam Radiobiology Status and Challenges: A PTCOG Radiobiology Subcommittee Report. Int J Part Ther. 2024 Sep; 13:100626 Epub 2024 Aug 08
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3. Bhandari C, Moffat A, Fakhry J, Malkoochi A, Nguyen A, Trinh B, Hoyt K, Story MD, Hasan T, Obaid G. A single photodynamic priming protocol augments delivery of ⍺-PD-L1 mAbs and induces immunogenic cell death in head and neck tumors. Photochem Photobiol. 2023 Oct 11 [Epub ahead of print]
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4. Man K, Liu J, Liang C, Corona C, Story MD, Meckes B, Yang Y. Biomimetic Human Lung Alveolar Interstitium Chip with Extended Longevity. ACS Appl Mater Interfaces. 2023 Aug 2; 15 (30):36888-36898 Epub 2023 July 18
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5. Zhang Y, Story M, Yeshitla S, Wang X, Scully RR, Theriot C, Wu H, Ryder VE, Lam CW. Persistent changes in expression of genes involved in inflammation and fibrosis in the lungs of rats exposed to airborne lunar dust. Inhal Toxicol. 2023 May-Jun; 35 (5-6):139-156 Epub 2023 Mar 26
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6. Narasimha Kumar Karanam, Lianghao Ding, Dat T Vo, Uma Giri, John S Yordy, Story Michael. miR-551a and miR-551b-3p target GLIPR2 and promote tumor growth in high-risk head and neck cancer by modulating autophagy Adv in Cancer Biol. 2022; 7.
   
7. Ding LH, Fallgren CM, Yu Y, McCarthy M, Edmondson EF, Ullrich RL, Weil MM, Story MD. Orthologs of human circulating miRNAs associated with hepatocellular carcinoma are elevated in mouse plasma months before tumour detection. Sci Rep. 2022 Jun 28; 12 (1):10927 Epub 2022 June 28
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8. Man K, Liu J, Phan KM, Wang K, Lee JY, Sun X, Story M, Saha D, Liao J, Sadat H, Yang Y. Dimensionality-Dependent Mechanical Stretch Regulation of Cell Behavior. ACS Appl Mater Interfaces. 2022 Apr 20; 14 (15):17081-17092 Epub 2022 Apr 05
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9. Ding L, Sishc BJ, Polsdofer E, Yordy JS, Facoetti A, Ciocca M, Saha D, Pompos A, Davis AJ, Story MD. Evaluation of the Response of HNSCC Cell Lines to gamma-Rays and (12)C Ions: Can Radioresistant Tumors Be Identified and Selected for (12)C Ion Radiotherapy? Front Oncol. 2022; 12:812961 Epub 2022 Feb 25
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10. Yu L, Lang Y, Hsu CC, Chen WM, Chiang JC, Hsieh JT, Story MD, Shang ZF, Chen BPC, Saha D. Mitotic phosphorylation of tumor suppressor DAB2IP maintains spindle assembly checkpoint and chromosomal stability through activating PLK1-Mps1 signal pathway and stabilizing mitotic checkpoint complex. Oncogene. 2022 Jan; 41 (4):489-501 Epub 2021 Nov 13
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11. Vo DT, Story MD. Facile and direct detection of human papillomavirus (HPV) DNA in cells using loop-mediated isothermal amplification (LAMP). Mol Cell Probes. 2021 Oct; 59:101760 Epub 2021 Aug 05
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12. Moore C, Hsu CC, Chen WM, Chen BPC, Han C, Story M, Aguilera T, Pop LM, Hannan R, Fu YX, Saha D, Timmerman R. Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy (PULSAR) in Preclinical Models Enhances Single-Agent Immune Checkpoint Blockade. Int J Radiat Oncol Biol Phys. 2021 Aug 1; 110 (5):1306-1316 Epub 2021 Mar 29
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13. Minnier J, Emmett MR, Perez R, Ding LH, Barnette BL, Larios RE, Hong C, Hwang TH, Yu Y, Fallgren CM, Story MD, Weil MM, Raber J. Associations between lipids in selected brain regions, plasma miRNA, and behavioral and cognitive measures following (28)Si ion irradiation. Sci Rep. 2021 Jul 21; 11 (1):14899 Epub 2021 July 21
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14. Ding LH, Yu Y, Edmondson EF, Weil MM, Pop LM, McCarthy M, Ullrich RL, Story MD. Transcriptomic analysis links hepatocellular carcinoma (HCC) in HZE ion irradiated mice to a human HCC subtype with favorable outcomes. Sci Rep. 2021 Jul 7; 11 (1):14052 Epub 2021 July 07
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15. Sishc BJ, Ding L, Nam TK, Heer CD, Rodman SN, Schoenfeld JD, Fath MA, Saha D, Pulliam CF, Langen B, Beardsley RA, Riley DP, Keene JL, Spitz DR, Story MD. Avasopasem manganese synergizes with hypofractionated radiation to ablate tumors through the generation of hydrogen peroxide. Sci Transl Med. 2021 May 12; 13 (593)
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16. Alsbeih G, Al-Harbi N, Ismail S, Story M. Impaired DNA Repair Fidelity in a Breast Cancer Patient With Adverse Reactions to Radiotherapy. Front Public Health. 2021; 9:647563 Epub 2021 June 07
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17. Karanam NK, Story MD. An overview of potential novel mechanisms of action underlying Tumor Treating Fields-induced cancer cell death and their clinical implications. Int J Radiat Biol. 2021; 97 (8):1044-1054 Epub 2020 Oct 29
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18. Zhong Y, Lai Y, Saha D, Story MD, Jia X, Stojadinovic S. Dose rate determination for preclinical total body irradiation. Phys Med Biol. 2020 Sep 8; 65 (17):175018 Epub 2020 Sept 08
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19. Abramowicz A, Labaj W, Mika J, Szoltysek K, Slezak-Prochazka I, Mielanczyk L, Story MD, Pietrowska M, Polanski A, Widlak P. MicroRNA Profile of Exosomes and Parental Cells is Differently Affected by Ionizing Radiation. Radiat Res. 2020 Aug 1; 194 (2):133-142
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20. Abramowicz A, Story MD. The Long and Short of It: The Emerging Roles of Non-Coding RNA in Small Extracellular Vesicles. Cancers (Basel). 2020 Jun 2; 12 (6) Epub 2020 June 02
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21. Karanam NK, Ding L, Aroumougame A, Story MD. Tumor treating fields cause replication stress and interfere with DNA replication fork maintenance: Implications for cancer therapy. Transl Res. 2020 Mar; 217:33-46 Epub 2019 Oct 21
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22. Vo DT, Karanam NK, Ding L, Saha D, Yordy JS, Giri U, Heymach JV, Story MD. miR-125a-5p Functions as Tumor Suppressor microRNA And Is a Marker of Locoregional Recurrence And Poor prognosis in Head And Neck Cancer. Neoplasia. 2019 Sep; 21 (9):849-862 Epub 2019 July 18
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23. Todorova PK, Fletcher-Sananikone E, Mukherjee B, Kollipara R, Vemireddy V, Xie XJ, Guida PM, Story MD, Hatanpaa K, Habib AA, Kittler R, Bachoo R, Hromas R, Floyd JR, Burma S. Radiation-Induced DNA Damage Cooperates with Heterozygosity of TP53 and PTEN to Generate High-Grade Gliomas. Cancer Res. 2019 Jul 15; 79 (14):3749-3761 Epub 2019 May 14
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24. Abramowicz A, Wojakowska A, Marczak L, Lysek-Gladysinska M, Smolarz M, Story MD, Polanska J, Widlak P, Pietrowska M. Ionizing radiation affects the composition of the proteome of extracellular vesicles released by head-and-neck cancer cells in vitro. J Radiat Res. 2019 May 1; 60 (3):289-297
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25. Wang Y, Liu ZG, Liu Z, Yuan H, Deng W, Li J, Huang Y, Kim BYS, Story MD, Jiang W. The Reciprocity between Radiotherapy and Cancer Immunotherapy. Clin Cancer Res. 2019 Mar 15; 25 (6):1709-1717 Epub 2018 Nov 09
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26. Story MD, Durante M. Radiogenomics. Med Phys. 2018 Nov; 45 (11):e1111-e1122
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27. Li Z, Jella KK, Jaafar L, Li S, Park S, Story MD, Wang H, Wang Y, Dynan WS. Exposure to galactic cosmic radiation compromises DNA repair and increases the potential for oncogenic chromosomal rearrangement in bronchial epithelial cells. Sci Rep. 2018 Jul 23; 8 (1):11038 Epub 2018 July 23
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28. Story MD, Wang J. Developing Predictive or Prognostic Biomarkers for Charged Particle Radiotherapy. Int J Part Ther. 2018 Summer; 5 (1):94-102
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29. Mohan R, Held KD, Story MD, Grosshans D, Capala J. Proceedings of the National Cancer Institute Workshop on Charged Particle Radiobiology. Int J Radiat Oncol Biol Phys. 2018 Mar 15; 100 (4):816-831 Epub 2017 Dec 21
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30. Saki M, Makino H, Javvadi P, Tomimatsu N, Ding LH, Clark JE, Gavin E, Takeda K, Andrews J, Saha D, Story MD, Burma S, Nirodi CS. EGFR Mutations Compromise Hypoxia-Associated Radiation Resistance through Impaired Replication Fork-Associated DNA Damage Repair. Mol Cancer Res. 2017 Nov; 15 (11):1503-1516 Epub 2017 Aug 11
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31. Mohamad O, Sishc BJ, Saha J, Pompos A, Rahimi A, Story MD, Davis AJ, Kim DWN. Carbon Ion Radiotherapy: A Review of Clinical Experiences and Preclinical Research, with an Emphasis on DNA Damage/Repair. Cancers (Basel). 2017 Jun 9; 9 (6) Epub 2017 June 09
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32. Karanam NK, Srinivasan K, Ding L, Sishc B, Saha D, Story MD. Tumor-treating fields elicit a conditional vulnerability to ionizing radiation via the downregulation of BRCA1 signaling and reduced DNA double-strand break repair capacity in non-small cell lung cancer cell lines. Cell Death Dis. 2017 Mar 30; 8 (3):e2711
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33. Laine A, Pompos A, Story M, Jiang S, Timmerman R, Choy H. International Symposium on Ion Therapy: Planning the First Hospital-Based Heavy Ion Therapy Center in the United States. Int J Part Ther. 2016 Winter; 2 (3):468-471 Epub 2016 Feb 09
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34. Indelicato DJ, Merchant T, Laperriere N, Lassen Y, Vennarini S, Wolden S, Hartsell W, Pankuch M, Brandal P, Law CK, Taylor R, Laskar S, Okcu MF, Bouffet E, Mandeville H, Bjork-Eriksson T, Nilsson K, Nystrom H, Constine LS, Story M, Timmermann B, Roberts K, Kortmann RD. Consensus Report From the Stockholm Pediatric Proton Therapy Conference. Int J Radiat Oncol Biol Phys. 2016 Oct 1; 96 (2):387-392
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35. Skinner HD, Giri U, Yang L, Woo SH, Story MD, Pickering CR, Byers LA, Williams MD, El-Naggar A, Wang J, Diao L, Shen L, Fan YH, Molkentine DP, Beadle BM, Meyn RE, Myers JN, Heymach JV. Proteomic Profiling Identifies PTK2/FAK as a Driver of Radioresistance in HPV-negative Head and Neck Cancer. Clin Cancer Res. 2016 Sep 15; 22 (18):4643-50 Epub 2016 Apr 01
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36. Zhang S, Matsunaga S, Lin YF, Sishc B, Shang Z, Sui J, Shih HY, Zhao Y, Foreman O, Story MD, Chen DJ, Chen BP. Spontaneous tumor development in bone marrow-rescued DNA-PKcs(3A/3A) mice due to dysfunction of telomere leading strand deprotection. Oncogene. 2016 Jul 28; 35 (30):3909-18 Epub 2015 Nov 30
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37. Park S, Kim SJ, Yu D, Peña-Llopis S, Gao J, Park JS, Chen B, Norris J, Wang X, Chen M, Kim M, Yong J, Wardak Z, Choe K, Story M, Starr T, Cheong JH, Hwang TH. An integrative somatic mutation analysis to identify pathways linked with survival outcomes across 19 cancer types. Bioinformatics. 2016 Jun 01; 32(11):1643-51. Epub 2015 Dec 03.
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38. Zhang Z, Wodzak M, Belzile O, Zhou H, Sishc B, Yan H, Stojadinovic S, Mason RP, Brekken RA, Chopra R, Story MD, Timmerman R, Saha D. Effective Rat Lung Tumor Model for Stereotactic Body Radiation Therapy. Radiat Res. 2016 Jun; 185 (6):616-22 Epub 2016 May 25
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39. Held KD, Blakely EA, Story MD, Lowenstein DI. Use of the NASA Space Radiation Laboratory at Brookhaven National Laboratory to Conduct Charged Particle Radiobiology Studies Relevant to Ion Therapy. Radiat Res. 2016 Jun; 185 (6):563-7 Epub 2016 May 19
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40. Zhang Y, Lu T, Wong M, Wang X, Stodieck L, Karouia F, Story M, Wu H. Transient gene and microRNA expression profile changes of confluent human fibroblast cells in spaceflight. FASEB J. 2016 Jun; 30 (6):2211-24 Epub 2016 Feb 25
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41. Hong ZY, Lee CG, Shim HS, Lee EJ, Song KH, Choi BW, Cho J, Story MD. Time, Dose, and Volume Responses in a Mouse Pulmonary Injury Model Following Ablative Irradiation. Lung. 2016 Feb; 194 (1):81-90 Epub 2015 Nov 12
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42. Niwa O, Barcellos-Hoff MH, Globus RK, Harrison JD, Hendry JH, Jacob P, Martin MT, Seed TM, Shay JW, Story MD, Suzuki K, Yamashita S, ICRP. ICRP Publication 131: Stem Cell Biology with Respect to Carcinogenesis Aspects of Radiological Protection. Ann ICRP. 2015 Dec; 44 (3-4):7-357
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43. Ding LH, Park S, Xie Y, Girard L, Minna JD, Story MD. Elucidation of changes in molecular signalling leading to increased cellular transformation in oncogenically progressed human bronchial epithelial cells exposed to radiations of increasing LET. Mutagenesis. 2015 Sep; 30 (5):685-94 Epub 2015 May 22
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44. Hong ZY, Song KH, Yoon JH, Cho J, Story MD. An experimental model-based exploration of cytokines in ablative radiation-induced lung injury in vivo and in vitro. Lung. 2015 Jun; 193 (3):409-19 Epub 2015 Mar 07
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45. Karanam NK, Ding L, Yordy JS, Giri U, Heymach JV, Story MD. Overexpression of miR-551a and miR-551b-3p down-regulate GLIPR2 to promote tumor growth in high-risk head and neck squamous cell carcinoma by modulating autophagy Biorxiv. 2015.
    
46. Neskey DM, Osman AA, Ow TJ, Katsonis P, McDonald T, Hicks SC, Hsu TK, Pickering CR, Ward A, Patel A, Yordy JS, Skinner HD, Giri U, Sano D, Story MD, Beadle BM, El-Naggar AK, Kies MS, William WN, Caulin C, Frederick M, Kimmel M, Myers JN, Lichtarge O. Evolutionary Action Score of TP53 Identifies High-Risk Mutations Associated with Decreased Survival and Increased Distant Metastases in Head and Neck Cancer. Cancer Res. 2015 Apr 1; 75 (7):1527-36 Epub 2015 Jan 29
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47. Keck MK, Zuo Z, Khattri A, Stricker TP, Brown CD, Imanguli M, Rieke D, Endhardt K, Fang P, Bragelmann J, DeBoer R, El-Dinali M, Aktolga S, Lei Z, Tan P, Rozen SG, Salgia R, Weichselbaum RR, Lingen MW, Story MD, Ang KK, Cohen EE, White KP, Vokes EE, Seiwert TY. Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes. Clin Cancer Res. 2015 Feb 15; 21 (4):870-81 Epub 2014 Dec 09
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48. Laine AM, Pompos A, Timmerman R, Jiang S, Story MD, Pistenmaa D, Choy H. The Role of Hypofractionated Radiation Therapy with Photons, Protons, and Heavy Ions for Treating Extracranial Lesions. Front Oncol. 2015; 5:302 Epub 2016 Jan 11
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49. Hong ZY, Eun SH, Park K, Choi WH, Lee JI, Lee EJ, Lee JM, Story MD, Cho J. Development of a small animal model to simulate clinical stereotactic body radiotherapy-induced central and peripheral lung injuries. J Radiat Res. 2014 Jul; 55 (4):648-57 Epub 2014 Feb 20
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50. Delgado O, Batten KG, Richardson JA, Xie XJ, Gazdar AF, Kaisani AA, Girard L, Behrens C, Suraokar M, Fasciani G, Wright WE, Story MD, Wistuba II, Minna JD, Shay JW. Radiation-enhanced lung cancer progression in a transgenic mouse model of lung cancer is predictive of outcomes in human lung and breast cancer. Clin Cancer Res. 2014 Mar 15; 20 (6):1610-22 Epub 2014 Jan 31
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51. Genik PC, Bielefeldt-Ohmann H, Liu X, Story MD, Ding L, Bush JM, Fallgren CM, Weil MM. Strain background determines lymphoma incidence in Atm knockout mice. Neoplasia. 2014 Feb; 16 (2):129-36
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52. Ng WL, Chen G, Wang M, Wang H, Story M, Shay JW, Zhang X, Wang J, Amin AR, Hu B, Cucinotta FA, Wang Y. OCT4 as a target of miR-34a stimulates p63 but inhibits p53 to promote human cell transformation. Cell Death Dis. 2014 Jan 23; 5 (1):e1024
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53. Alsbeih G, Brock W, Story M. Misrepair of DNA double-strand breaks in patient with unidentified chromosomal fragility syndrome and family history of radiosensitivity. Int J Radiat Biol. 2014 Jan; 90 (1):53-9
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54. Ding LH, Park S, Peyton M, Girard L, Xie Y, Minna JD, Story MD. Distinct transcriptome profiles identified in normal human bronchial epithelial cells after exposure to gamma-rays and different elemental particles of high Z and energy. BMC Genomics. 2013 Jun 1; 14:372 Epub 2013 June 01
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55. Singh M, Hunt CR, Pandita RK, Kumar R, Yang CR, Horikoshi N, Bachoo R, Serag S, Story MD, Shay JW, Powell SN, Gupta A, Jeffery J, Pandita S, Chen BP, Deckbar D, Lobrich M, Yang Q, Khanna KK, Worman HJ, Pandita TK. Lamin A/C depletion enhances DNA damage-induced stalled replication fork arrest. Mol Cell Biol. 2013 Mar; 33 (6):1210-22 Epub 2013 Jan 14
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56. Ghayee HK, Bhagwandin VJ, Stastny V, Click A, Ding LH, Mizrachi D, Zou YS, Chari R, Lam WL, Bachoo RM, Smith AL, Story MD, Sidhu S, Robinson BG, Nwariaku FE, Gazdar AF, Auchus RJ, Shay JW. Progenitor cell line (hPheo1) derived from a human pheochromocytoma tumor. PLoS One. 2013; 8 (6):e65624 Epub 2013 June 13
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57. Steffen LS, Bacher JW, Peng Y, Le PN, Ding LH, Genik PC, Ray FA, Bedford JS, Fallgren CM, Bailey SM, Ullrich RL, Weil MM, Story MD. Molecular characterisation of murine acute myeloid leukaemia induced by 56Fe ion and 137Cs gamma ray irradiation. Mutagenesis. 2013 Jan; 28 (1):71-9 Epub 2012 Sept 17
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58. Story M, Ding LH, Brock WA, Ang KK, Alsbeih G, Minna J, Park S, Das A. Defining molecular and cellular responses after low and high linear energy transfer radiations to develop biomarkers of carcinogenic risk or therapeutic outcome. Health Phys. 2012 Nov; 103 (5):596-606
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59. Ausborn NL, Le QT, Bradley JD, Choy H, Dicker AP, Saha D, Simko J, Story MD, Torossian A, Lu B. Molecular profiling to optimize treatment in non-small cell lung cancer: a review of potential molecular targets for radiation therapy by the translational research program of the radiation therapy oncology group. Int J Radiat Oncol Biol Phys. 2012 Jul 15; 83 (4):e453-64 Epub 2012 Apr 18
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60. Rifkin LH, Stojadinovic S, Stewart CH, Song KH, Maxted MC, Bell MH, Kashefi NS, Speiser MP, Saint-Cyr M, Story MD, Rohrich RJ, Brown SA, Solberg TD. An athymic rat model of cutaneous radiation injury designed to study human tissue-based wound therapy. Radiat Oncol. 2012 May 08; 7:68.
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61. Li B, Ding L, Li W, Story MD, Pace BS. Characterization of the transcriptome profiles related to globin gene switching during in vitro erythroid maturation. BMC Genomics. 2012 Apr 26; 13:153
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62. Williams PD, Owens CR, Dziegielewski J, Moskaluk CA, Read PW, Larner JM, Story MD, Brock WA, Amundson SA, Lee JK, Theodorescu D. Cyclophilin B expression is associated with in vitro radioresistance and clinical outcome after radiotherapy. Neoplasia. 2011 Dec; 13 (12):1122-31
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63. Huang J, Mirel D, Pugh E, Xing C, Robinson PN, Pertsemlidis A, Ding L, Kozlitina J, Maher J, Rios J, Story M, Marthandan N, Scheuermann RH. Minimum Information about a Genotyping Experiment (MIGEN). Stand Genomic Sci. 2011 Nov 30; 5 (2):224-9 Epub 2011 Nov 22
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64. Mangala LS, Zhang Y, He Z, Emami K, Ramesh GT, Story M, Rohde LH, Wu H. Effects of simulated microgravity on expression profile of microRNA in human lymphoblastoid cells. J Biol Chem. 2011 Sep 16; 286 (37):32483-90 Epub 2011 July 20
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65. Chen M, Xie Y, Story M. An Exponential-Gamma Convolution Model for Background Correction of Illumina BeadArray Data. Commun Stat Theory Methods. 2011 Sep 1; 40 (17):3055-3069
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66. Asaithamby A, Hu B, Delgado O, Ding LH, Story MD, Minna JD, Shay JW, Chen DJ. Irreparable complex DNA double-strand breaks induce chromosome breakage in organotypic three-dimensional human lung epithelial cell culture. Nucleic Acids Res. 2011 Jul; 39 (13):5474-88 Epub 2011 Mar 18
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67. Zhang S, Yajima H, Huynh H, Zheng J, Callen E, Chen HT, Wong N, Bunting S, Lin YF, Li M, Lee KJ, Story M, Gapud E, Sleckman BP, Nussenzweig A, Zhang CC, Chen DJ, Chen BP. Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair. J Cell Biol. 2011 Apr 18; 193 (2):295-305 Epub 2011 Apr 11
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68. Moeller BJ, Yordy JS, Williams MD, Giri U, Raju U, Molkentine DP, Byers LA, Heymach JV, Story MD, Lee JJ, Sturgis EM, Weber RS, Garden AS, Ang KK, Schwartz DL. DNA repair biomarker profiling of head and neck cancer: Ku80 expression predicts locoregional failure and death following radiotherapy. Clin Cancer Res. 2011 Apr 1; 17 (7):2035-43 Epub 2011 Feb 24
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69. Kwak YT, Radaideh SM, Ding L, Li R, Frenkel E, Story MD, Girard L, Minna J, Verma UN. Cells lacking IKKalpha show nuclear cyclin D1 overexpression and a neoplastic phenotype: role of IKKalpha as a tumor suppressor. Mol Cancer Res. 2011 Mar; 9 (3):341-9 Epub 2011 Feb 11
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70. Koto M, Cho H, Riesterer O, Giri U, Story MD, Ha CS, Raju U. Human lymphoma cells develop resistance to radiation in the presence of astrocytes in vitro. Anticancer Res. 2011 Jan; 31 (1):33-8
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71. Wang J, Byers LA, Yordy JS, Liu W, Shen L, Baggerly KA, Giri U, Myers JN, Ang KK, Story MD, Girard L, Minna JD, Heymach JV, Coombes KR. Blasted cell line names. Cancer Inform. 2010 Oct 14; 9:251-5
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72. Camacho CV, Mukherjee B, McEllin B, Ding LH, Hu B, Habib AA, Xie XJ, Nirodi CS, Saha D, Story MD, Balajee AS, Bachoo RM, Boothman DA, Burma S. Loss of p15/Ink4b accompanies tumorigenesis triggered by complex DNA double-strand breaks. Carcinogenesis. 2010 Oct; 31 (10):1889-96 Epub 2010 July 26
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73. Cho J, Kodym R, Seliounine S, Richardson JA, Solberg TD, Story MD. High dose-per-fraction irradiation of limited lung volumes using an image-guided, highly focused irradiator: simulating stereotactic body radiotherapy regimens in a small-animal model. Int J Radiat Oncol Biol Phys. 2010 Jul 1; 77 (3):895-902
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74. Saha D, Watkins L, Yin Y, Thorpe P, Story MD, Song K, Raghavan P, Timmerman R, Chen B, Minna JD, Solberg TD. An orthotopic lung tumor model for image-guided microirradiation in rats. Radiat Res. 2010 Jul; 174 (1):62-71
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75. Roig AI, Hight SK, Minna JD, Shay JW, Rusek A, Story MD. DNA damage intensity in fibroblasts in a 3-dimensional collagen matrix correlates with the Bragg curve energy distribution of a high LET particle. Int J Radiat Biol. 2010 Mar; 86 (3):194-204
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76. Cho H, Koto M, Riesterer O, Molkentine DP, Giri U, Milas L, Story MD, Ha CS, Raju U. Imexon augments sensitivity of human lymphoma cells to ionizing radiation: in vitro experimental study. Anticancer Res. 2009 Nov; 29 (11):4409-15
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77. Kodym R, Kodym E, Story MD. 2'-5'-Oligoadenylate synthetase is activated by a specific RNA sequence motif. Biochem Biophys Res Commun. 2009 Oct 16; 388 (2):317-22 Epub 2009 Aug 05
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78. Kodym E, Kodym R, Reis AE, Habib AA, Story MD, Saha D. The small-molecule CDK inhibitor, SNS-032, enhances cellular radiosensitivity in quiescent and hypoxic non-small cell lung cancer cells. Lung Cancer. 2009 Oct; 66 (1):37-47 Epub 2009 Feb 03
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79. Huang X, Ding L, Bennewith KL, Tong RT, Welford SM, Ang KK, Story M, Le QT, Giaccia AJ. Hypoxia-inducible mir-210 regulates normoxic gene expression involved in tumor initiation. Mol Cell. 2009 Sep 24; 35 (6):856-67
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80. Park S, Zhao D, Hatanpaa KJ, Mickey BE, Saha D, Boothman DA, Story MD, Wong ET, Burma S, Georgescu MM, Rangnekar VM, Chauncey SS, Habib AA. RIP1 activates PI3K-Akt via a dual mechanism involving NF-kappaB-mediated inhibition of the mTOR-S6K-IRS1 negative feedback loop and down-regulation of PTEN. Cancer Res. 2009 May 15; 69 (10):4107-11 Epub 2009 May 12
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81. Ramdas L, Giri U, Ashorn CL, Coombes KR, El-Naggar A, Ang KK, Story MD. miRNA expression profiles in head and neck squamous cell carcinoma and adjacent normal tissue. Head Neck. 2009 May; 31 (5):642-54
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82. Kodym R, Kodym E, Story MD. Short double-stranded RNAs of specific sequence activate ribosomal TAK1-D and induce a global inhibition of translation. Biol Chem. 2009 May-Jun; 390 (5-6):453-62
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83. Ali MA, Reis A, Ding LH, Story MD, Habib AA, Chattopadhyay A, Saha D. SNS-032 prevents hypoxia-mediated glioblastoma cell invasion by inhibiting hypoxia inducible factor-1alpha expression. Int J Oncol. 2009 Apr; 34 (4):1051-60
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84. Xie Y, Wang X, Story M. Statistical methods of background correction for Illumina BeadArray data. Bioinformatics. 2009 Mar 15; 25 (6):751-7 Epub 2009 Feb 04
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85. Ding LH, Xie Y, Park S, Xiao G, Story MD. Enhanced identification and biological validation of differential gene expression via Illumina whole-genome expression arrays through the use of the model-based background correction methodology. Nucleic Acids Res. 2008 Jun; 36 (10):e58 Epub 2008 May 01
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86. Klopp AH, Jhingran A, Ramdas L, Story MD, Broadus RR, Lu KH, Eifel PJ, Buchholz TA. Gene expression changes in cervical squamous cell carcinoma after initiation of chemoradiation and correlation with clinical outcome. Int J Radiat Oncol Biol Phys. 2008 May 1; 71 (1):226-36
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87. Asaithamby A, Uematsu N, Chatterjee A, Story MD, Burma S, Chen DJ. Repair of HZE-particle-induced DNA double-strand breaks in normal human fibroblasts. Radiat Res. 2008 Apr; 169 (4):437-46
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88. Park C, Papiez L, Zhang S, Story M, Timmerman RD. Universal survival curve and single fraction equivalent dose: useful tools in understanding potency of ablative radiotherapy. Int J Radiat Oncol Biol Phys. 2008 Mar 1; 70 (3):847-52
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89. Kodym R, Kodym E, Story MD. Sequence-specific activation of TAK1-D by short double-stranded RNAs induces apoptosis in NCI-H460 cells. RNA. 2008 Mar; 14 (3):535-42 Epub 2008 Jan 29
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90. Das AK, Chen BP, Story MD, Sato M, Minna JD, Chen DJ, Nirodi CS. Somatic mutations in the tyrosine kinase domain of epidermal growth factor receptor (EGFR) abrogate EGFR-mediated radioprotection in non-small cell lung carcinoma. Cancer Res. 2007 Jun 1; 67 (11):5267-74
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91. Das AK, Sato M, Story MD, Peyton M, Graves R, Redpath S, Girard L, Gazdar AF, Shay JW, Minna JD, Nirodi CS. Non-small-cell lung cancers with kinase domain mutations in the epidermal growth factor receptor are sensitive to ionizing radiation. Cancer Res. 2006 Oct 1; 66 (19):9601-8
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92. Giri U, Ashorn CL, Ramdas L, Stivers DN, Coombes K, El-Naggar AK, Ang KK, Story MD. Molecular signatures associated with clinical outcome in patients with high-risk head-and-neck squamous cell carcinoma treated by surgery and radiation. Int J Radiat Oncol Biol Phys. 2006 Mar 1; 64 (3):670-7 Epub 2005 Nov 10
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93. Giri U, Terry NH, Kala SV, Lieberman MW, Story MD. Elimination of the differential chemoresistance between the murine B-cell lymphoma LY-ar and LY-as cell lines after arsenic (As2O3) exposure via the overexpression of gsto1 (p28). Cancer Chemother Pharmacol. 2005 Jun; 55 (6):511-21 Epub 2005 Mar 11
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94. Zhang X, Succi J, Feng Z, Prithivirajsingh S, Story MD, Legerski RJ. Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response. Mol Cell Biol. 2004 Oct; 24 (20):9207-20
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95. Nishikawa T, Munshi A, Story MD, Ismail S, Stevens C, Chada S, Meyn RE. Adenoviral-mediated mda-7 expression suppresses DNA repair capacity and radiosensitizes non-small-cell lung cancer cells. Oncogene. 2004 Sep 16; 23 (42):7125-31
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96. Prithivirajsingh S, Story MD, Bergh SA, Geara FB, Ang KK, Ismail SM, Stevens CW, Buchholz TA, Brock WA. Accumulation of the common mitochondrial DNA deletion induced by ionizing radiation. FEBS Lett. 2004 Jul 30; 571 (1-3):227-32
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97. Buchholz TA, Weil MM, Ashorn CL, Strom EA, Sigurdson A, Bondy M, Chakraborty R, Cox JD, McNeese MD, Story MD. A Ser49Cys variant in the ataxia telangiectasia, mutated, gene that is more common in patients with breast carcinoma compared with population controls. Cancer. 2004 Apr 1; 100 (7):1345-51
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98. Ismail SM, Puppi M, Prithivirajsingh S, Munshi A, Raju U, Meyn RE, Buchholz TA, Story MD, Brock WA, Milas L, Thames HD, Stevens CW. Predicting radiosensitivity using DNA end-binding complex analysis. Clin Cancer Res. 2004 Feb 15; 10 (4):1226-34
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99. Alsbeih G, Brock WA, Terry N, Story MD. Analysis of radiation-induced DNA double-strand breaks misrepair is not compromized by broken DNA in human fibroblasts. Radiat Environ Biophys. 2003 Jul; 42 (2):107-11 Epub 2003 June 11
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100. Alsbeih G, Story MD, Maor MH, Geara FB, Brock WA. Chromosomal fragility syndrome and family history of radiosensitivity as indicators for radiotherapy dose modification. Radiother Oncol. 2003 Mar; 66 (3):341-4
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101. Hassan KA, Ang KK, El-Naggar AK, Story MD, Lee JI, Liu D, Hong WK, Mao L. Cyclin B1 overexpression and resistance to radiotherapy in head and neck squamous cell carcinoma. Cancer Res. 2002 Nov 15; 62 (22):6414-7
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102. Chan DW, Chen BP, Prithivirajsingh S, Kurimasa A, Story MD, Qin J, Chen DJ. Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks. Genes Dev. 2002 Sep 15; 16 (18):2333-8
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103. Buchholz TA, Wu X, Hussain A, Tucker SL, Mills GB, Haffty B, Bergh S, Story M, Geara FB, Brock WA. Evidence of haplotype insufficiency in human cells containing a germline mutation in BRCA1 or BRCA2. Int J Cancer. 2002 Feb 10; 97 (5):557-61
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104. Kurland JF, Kodym R, Story MD, Spurgers KB, McDonnell TJ, Meyn RE. NF-kappaB1 (p50) homodimers contribute to transcription of the bcl-2 oncogene. J Biol Chem. 2001 Nov 30; 276 (48):45380-6 Epub 2001 Sept 20
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105. Nguyen LN, Munshi A, Hobbs ML, Story MD, Meyn RD. Paclitaxel restores radiation-induced apoptosis in a bcl-2-expressing, radiation-resistant lymphoma cell line. Int J Radiat Oncol Biol Phys. 2001 Mar 15; 49 (4):1127-32
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106. Li L, Story M, Legerski RJ. Cellular responses to ionizing radiation damage. Int J Radiat Oncol Biol Phys. 2001 Mar 15; 49 (4):1157-62
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107. Kodym R, Calkins PR, Story MD. Anthracycline-induced erythroid differentiation of K562 cells is inhibited by p28, a novel mammalian glutathione-binding stress protein. Leuk Res. 2001 Feb; 25 (2):151-6
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108. Bonnen PE, Story MD, Ashorn CL, Buchholz TA, Weil MM, Nelson DL. Haplotypes at ATM identify coding-sequence variation and indicate a region of extensive linkage disequilibrium. Am J Hum Genet. 2000 Dec; 67 (6):1437-51 Epub 2000 Nov 14
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109. Dynlacht JR, Earles M, Henthorn J, Roberts ZV, Howard EW, Seno JD, Sparling D, Story MD. Degradation of the nuclear matrix is a common element during radiation-induced apoptosis and necrosis. Radiat Res. 1999 Dec; 152 (6):590-603
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110. Kurimasa A, Kumano S, Boubnov NV, Story MD, Tung CS, Peterson SR, Chen DJ. Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoining. Mol Cell Biol. 1999 May; 19 (5):3877-84
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111. Kodym R, Calkins P, Story M. The cloning and characterization of a new stress response protein. A mammalian member of a family of theta class glutathione s-transferase-like proteins. J Biol Chem. 1999 Feb 19; 274 (8):5131-7
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112. Dynlacht JR, Story MD, Zhu WG, Danner J. Lamin B is a prompt heat shock protein. J Cell Physiol. 1999 Jan; 178 (1):28-34
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113. Story MD, Meyn RE. Modulation of apoptosis and enhancement of chemosensitivity by decreasing cellular thiols in a mouse B-cell lymphoma cell line that overexpresses bcl-2. Cancer Chemother Pharmacol. 1999; 44 (5):362-6
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114. Story MD, Mirkovic N, Hunter N, Meyn RE. Bcl-2 expression correlates with apoptosis induction but not tumor growth delay in transplantable murine lymphomas treated with different chemotherapy drugs. Cancer Chemother Pharmacol. 1999; 44 (5):367-71
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115. Buchholz TA, Weil MM, Story MD, Strom EA, Brock WA, McNeese MD. Tumor suppressor genes and breast cancer. Radiat Oncol Investig. 1999; 7 (2):55-65
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116. Breton C, Story MD, Meyn RE. Bcl-2 expression correlates with apoptosis induction but not loss of clonogenic survival in small cell lung cancer cell lines treated with etoposide. Anticancer Drugs. 1998 Oct; 9 (9):751-7
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117. Story M, Kodym R. Signal transduction during apoptosis; implications for cancer therapy. Front Biosci. 1998 Mar 23; 3:d365-75
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118. Mirkovic N, Voehringer DW, Story MD, McConkey DJ, McDonnell TJ, Meyn RE. Resistance to radiation-induced apoptosis in Bcl-2-expressing cells is reversed by depleting cellular thiols. Oncogene. 1997 Sep 18; 15 (12):1461-70
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119. Voehringer DW, Story MD, O'Neil RG, Meyn RE. Modulating Ca2+ in radiation-induced apoptosis suppresses DNA fragmentation but does not enhance clonogenic survival. Int J Radiat Biol. 1997 Mar; 71 (3):237-43
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120. Dynlacht JR, Henthorn J, O'Nan C, Dunn ST, Story MD. Flow cytometric analysis of nuclear matrix proteins: method and potential applications. Cytometry. 1996 Aug 1; 24 (4):348-59
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121. Chen F, Peterson SR, Story MD, Chen DJ. Disruption of DNA-PK in Ku80 mutant xrs-6 and the implications in DNA double-strand break repair. Mutat Res. 1996 Jan 2; 362 (1):9-19
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122. Neamati N, Voehringer DW, Story MD, Meyn RE. Modulation of radiation-induced apoptosis by lazaroids Radiat Oncol Invest. 1996; (4):66-73.
     
123. Story MD, Voehringer DW, Malone CG, Hobbs ML, Meyn RE. Radiation-induced apoptosis in sensitive and resistant cells isolated from a mouse lymphoma. Int J Radiat Biol. 1994 Dec; 66 (6):659-68
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124. Story MD, Mendoza EA, Meyn RE, Tofilon PJ. Pulsed-field gel electrophoretic analysis of DNA double-strand breaks in mammalian cells using photostimulable storage phosphor imaging. Int J Radiat Biol 1994 May; 65 (5):523-8
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125. Tomasovic SP, Vasey TA, Story MD, Stephens LC, Klostergaard J. Cytotoxic manifestations of the interaction between hyperthermia and TNF: DNA fragmentation. Int J Hyperthermia. 1994 Mar-Apr; 10 (2):247-62
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126. Meyn RE, Stephens LC, Voehringer DW, Story MD, Mirkovic N, Milas L. Biochemical modulation of radiation-induced apoptosis in murine lymphoma cells. Radiat Res. 1993 Dec; 136 (3):327-34
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127. Story MD, Garrett KC, Tofilon PJ, Meyn RE. Influence of irradiation conditions on the measurement of DNA double-strand breaks by pulsed-field gel electrophoresis. Int J Radiat Biol. 1993 Mar; 63 (3):297-304
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128. Robertson LE, Chubb S, Meyn RE, Story M, Ford R, Hittelman WN, Plunkett W. Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2'-deoxyadenosine and 9-beta-D-arabinosyl-2-fluoroadenine. Blood. 1993 Jan 1; 81 (1):143-50
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129. Story MD, Voehringer DW, Stephens LC, Meyn RE. L-asparaginase kills lymphoma cells by apoptosis. Cancer Chemother Pharmacol. 1993; 32 (2):129-33
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130. Story MD, Stephens LC, Tomasovic SP, Meyn RE. A role for calcium in regulating apoptosis in rat thymocytes irradiated in vitro. Int J Radiat Biol. 1992 Feb; 61 (2):243-51
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131. Dolf G, Meyn RE, Curley D, Prather N, Story MD, Boman BM, Siciliano MJ, Hewitt RR. Extrachromosomal amplification of the epidermal growth factor receptor gene in a human colon carcinoma cell line. Genes Chromosomes Cancer. 1991 Jan; 3 (1):48-54
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132. Lett JT, Cox AB, Story MD, Ehmann UK, Blakely EA. Responses of synchronous L5178Y S/S cells to heavy ions and their significance for radiobiological theory. Proc R Soc Lond B Biol Sci. 1989 Jun 22; 237 (1286):27-42
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133. Lett JT, Cox AB, Story MD. The role of repair in the survival of mammalian cells from heavy ion irradiation: approximation to the ideal case of target theory. Adv Space Res. 1989; 9 (10):99-104
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