Clinical Trials

The purpose of this study is to determine the effectiveness of a pre-operative and post-operative psychosocial intervention to improve acute pain outcomes and reduce opioid use in adolescents undergoing major musculoskeletal surgery.
 

This is a prospective observational cohort study.

This study will address important gaps in knowledge that hamper the development of evidence-based guidelines for acute pain management by prospectively following patients for 180 days and collecting detailed information on patients’ self-reported experience of pain and their corresponding analgesic use.

This study will invite opioid-naïve patients receiving an opioid prescription for the treatment of acute pain in primary or urgent care, an emergency department, or a dental office. Opioid naive patients are those who self-report no opioid use in the prior 6 months. For the purpose of the study, ...

The purpose of this study is to evaluate the safety of TRV130 for treatment of patients who have moderate to severe pain caused by medical conditions or surgery, and who require IV opioid therapy.

The purpose of this study is to evaluate the effectiveness of remote electrical neuromodulation with Nerivio ® (Theranica Bio-electronics, Ltd.) for treatment of acute procedural pain in patients receiving onabotulinumtoxinA for the treatment of chronic migraine.  

The purpose of this study is to validate the diagnostic accuracy of a transportable magnetocardiograph device for acute coronary syndrome (ACS), focusing on rule-out capability, in patients who present to the emergency department with chest pain symptoms consistent with ACS.

The purpose of this study is to see if using two-dimensional speckle tracking echocardiography improves the initial diagnosis of acute coronary syndrome in patients with chest pain who visit the emergency department. 

The purpose of this study is to develop an evidenced-based guideline for pediatric opioid prescribing guideline from the emergency department for long bone fractures to more closely tailor pain management to abuse potential. 

The purpose of this study is to evaluate the effectiveness and safety of intravenous Sodium Thiosulfate Injection for treatment of acute calciphylaxis-associated pain in chronic hemodialysis patients.

The purpose of this study is to screen for unique or characteristic circulating peptides, hormonal biomarkers and circulating mRNA in patients who have experienced spontaneous coronary artery dissection (SCAD).