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A Study to Evaluate DDP3 as a Predictor of Cardiogenic Shock in Patients Presenting with Cardiac Symptoms
Rochester, MN
The purpose of this study is to evaluate whether DDP3 identifies patients at early risk of cardiogenic shock presenting with STEMI in order to benefit from more aggressive cardiology scrutiny.
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A Study to Validate Current Machine Learning Models for Hemodynamic Instability in Humans
Rochester, MN
The primary purpose of this study is to provide a subset of data using protocols of tolerance to lower-body negative pressure for validation of a commercially available wearable device that will be used in predicting hemorrhagic shock in persons suffering civilian and battlefield trauma.
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A Study to Evaluate a Multiplex Precision Medicine System for Early Warning of Progression Toward Shock After Trauma
Rochester, MN
The purpose of this study is to evaluate performance of already developed porcine algorithms in the human “models” of lower body negative pressure (LBNP), and to obtain human model training and validation data sets from LBNP for further refinement of the algorithms.
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A Study to Evaluate Noninvasive Ultrasound Elastography of Kidney and Lung in Assessment of Volume Status in ICU Patients
Rochester, MN
The primary purpose of this study is to assess the feasibility of performing lung and kidney and lung ultrasound elastography among patients with critical illness from different etiologies that could be associated with volume overload.
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A Study to Investigate Outcomes and Management Effectiveness of Cardiogenic Shock II Patients
Rochester, MN
The purpose of this study is to develop a registry of patients with clinical cardiogenic shock (CS) in order to allow better definition of several key issues regarding cardiogenic shock.
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A Study of LJPC-501 in Patients with Catecholamine-Resistant Hypotension
Rochester, MN
The purpose of this study is to assess the effect of LJPC-501 (angiotensin II) on the mean arterial pressure in adult patients with catecholamine-resistant hypotension.
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A Study of the Effect, Safety, and Tolerability of LJPC-501 in Patients with Catecholamine-Resistant Hypotension
Scottsdale/Phoenix, AZ
The purpose of this study is to assess the effect, safety, and tolerability of LJPC-501 (angiotensin II) in adult patients diagnosed with catecholamine-resistant hypotension.
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Study to Determine Safety and Effectiveness of Ascorbic Acid, Corticosteroids, and Thiamine in Treating Sepsis and Septic Shock
Scottsdale/Phoenix, AZ
The purpose of this study is to determine whether the combination of Ascorbic Acid (Vitamin C), Thiamine (Vitamin B1), and Corticosteroids improves the trajectory of organ failure and reduces mortality in patients with sepsis and septic shock as compared to placebo.