Faculty

Bernard R. Bendok, M.D.

Clinical Studies

Chronic Subdural Hematoma Treatment With Embolization Versus Surgery Study (CHESS) Scottsdale/Phoenix, Ariz.
The purpose of study is to test in moderately symptomatic chronic subdural hematoma (CSDH) patients if middle meningeal artery embolization (MMAE) can be used as an alternative to conventional open surgery.
Patient-Specific Preclinical Evaluation Of Robotic-Assisted Neuroendovascular Access To Support An In-Human Early Feasibility Trial Scottsdale/Phoenix, Ariz.
The purpose of this study is to characterize the performance of manual MMA access in humans per standard of care.
Phase II Randomized Trial Of Glucose Monitoring In Glioblastoma Rochester, Minn.
The purpose of this study is to compare standard glucose monitoring versus continuous glucose monitoring (CGM) with endocrinology-guided intervention in newly diagnosed glioblastoma (GBM) patients receiving standard-of-care therapy.

A Phase I, Open-Label, Multiple Dose, Dose-escalation Study to Evaluate the Safety, Tolerability and Antitumor Activity of Anti-B7-H3 CAR-T Cell Injection (TX103) in Subjects with Recurrent or Progressive Grade 4 Glioma. (TX103T-RG008) Rochester, Minn., Jacksonville, Fla., Scottsdale/Phoenix, Ariz.
The purpose of this study is to evaluate the safety and tolerability of Anti-B7-H3 CAR-T Cell Injection administered via intraventricular [ICV] delivery or intracavitary [ICT]/ ICV dual delivery in subjects with recurrent or progressive grade 4 glioma. To determine the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D) for intracranial infusion of Anti-B7-H3 CAR-T Cell Injection.
Phase II Randomized Trial Of Glucose Monitoring In Glioblastoma Scottsdale/Phoenix, Ariz.
The purpose of this study is to compare standard glucose monitoring versus continuous glucose monitoring (CGM) with endocrinology-guided intervention in newly diagnosed glioblastoma (GBM) patients receiving standard-of-care therapy.

A Phase 3 Multicenter Study of Gleolan (Aminolevulinic Acid Hydrochloride) to Enhance Visualization of Tumor in Patients with Newly Diagnosed or Recurrent Meningiomas Rochester, Minn., Scottsdale/Phoenix, Ariz.
The purpose of this study is to investigate the safety, diagnostic performance, and clinical usefulness of the imaging agent Gleolan™ (Aminolevulinic Acid Hydrochloride, ALA HCl, ALA, 5-ALA), an orally administered imaging agent for the real-time detection and visualization of meningiomas during tumor resection surgery. ALA is a prodrug that is metabolized intracellularly to form the fluorescent molecule Protoporphyrin IX (PpIX).
Assessing Patient-Specific Anatomy with Holography/Augmented Reality and 3D Printing in Patient Education Scottsdale/Phoenix, Ariz.
The purpose of this study is to assess if using holography/ Augmented Reality and 3D-printed models to visualize intracranial diseases and aid in patient education.
Feasibility Study Comparing the Utility of GLOW800 and FL800 Intraoperative ICG-VA Tools for Intracranial Lesions Scottsdale/Phoenix, Ariz.
The purpose of this study is to comparatively evaluate the use of the GLOW800 visualization tool for ICG-VA versus the standard of care visualization tool FL800.