Alejandro A. Rabinstein, M.D.

The purpose of this study is to learn whether asundexian works better than placebo at reducing ischemic strokes in participants who recently had a non-cardioembolic ischemic stroke or temporary stroke-like symptoms when given in addition to standard antiplatelet therapy.  

The purpose of the study is to determine the effectiveness and safety of redasemtide for the treatment of adult participants with acute ischemic stroke. 

The purposes of this study are to determine if the Braincare monitor can identify progression of mass effect from non-traumatic hemispheric brain lesions through continuous analysis of the ICP waveform and comparison of changes in ICP waveform from side to side, and to evaluate if changes in ICP curve indicative of progression of mass effect occur earlier than clinical changes that would routinely lead to repeat brain imaging.

The purpose of this study is to determine if cerebral perfusion imaging can identify a subset of patients who are most likely to have a favorable outcome after thrombectomy treatment. We hypothesize that patients with a favorable Critical Area Perfusion Score (CAPS≤3) on cerebral perfusion imaging will have a favorable response to revascularization by thrombectomy and that patients with a CAPS>3 will not.

The purpose of this study is to find the trends, risk factors and outcomes of acute brain injury in critically ill intensive care patients, and to develop a brain injury scale useful for large sized research studies.

The purpose of this study is to assess how accurately a portable single-channel EEG device (Epilog™ by Epitel) detects generalized non-convulsive seizures, and to determine the feasibility of use of this device in an acute setting such as the Emergency Department (ED).

Objectives - Primary: To test the hypothesis that apixaban is superior to aspirin for the prevention of recurrent stroke in patients with cryptogenic ischemic stroke and atrial cardiopathy. - Secondary: To test the hypothesis that the relative efficacy of apixaban over aspirin increases with the severity of atrial cardiopathy.

The purpose of this study is to assess short and long term outcomes and factors related to poor prognosis in patients with neuroinvasive West Nile disease

The purpose of this study is to establish a collection of health related data and biological samples that will enable researchers to understand the cause of cryptogenic new-onset refractory status epilepticus (NORSE), to identify the key determinants of outcome and to determine the best management strategy.

The study is a prospective, multi-center, non-randomized, open label observational study. The objective of this study is to compare the accuracy of the EyeBOX to a clinical diagnosis of abnormal ICP as determined by an external ventriculostomy drain (EVD) or ventriculostomy catheter.

The purpose of this study is to assess the ability of Non-invasive near-infrared spectroscopy (NIRS) as compared to Licox to detect regional changes in brain tissue oxygenation, and to compare changes in management based on data derived from monitoring.

Determine if the use of sequential pneumatic compression in the arm can prevent the formation of venous clots related to the presence of a peripherally inserted central catheter (PICC).