Jeffrey R. Janus, M.D.

The purpose of this study is to develop a salivary repository protocol to boost salivary regenerative medicine research.

The purpose of this study is to determine how well sentinel lymph node biopsy works and compares sentinel lymph node biopsy surgery to standard neck dissection as part of the treatment for early-stage oral cavity cancer.  

The purpose of this study is to determine how well sentinel lymph node biopsy works and compares sentinel lymph node biopsy surgery to standard neck dissection as part of the treatment for early-stage oral cavity cancer.  

The purpose of this study is to obtain fat tissue from patients undergoing neck surgery for the treatment of upper head and neck cancer, and to prepare it in the lab as stem cells.

The purpose of this study is to characterize the inflammatory markers of free flap reconstructive head and neck surgery in humans by analyzing specific inflammatory markers in blood samples from patients with the hope of better understanding free flap physiology in order to eventually improve patient outcomes.  

The purpose of this study is to determine the benefit to postoperative facial nerve function of using electromyography (EMG) based monitoring of facial nerve function during surgery to remove the parotid gland for superficial benign lesions.

Can pericranium be used to regrow bone for the repair of critical mandibular defects?

We are currently working on a research project to investigate the use of stem cells to regenerate bone in the jaw that is unhealthy as a result of osteoradionecrosis (ORN). Stem cells have the capability to develop into bone, cartilage, fat, skin or blood vessels, and are thought to be involved in the healing process. Using your discarded jawbone (if this is being removed) and/or fat, we can generate stem cells and see if they can heal the bone in the laboratory setting. If this proves successful, we may be able to use this technology in patients to avoid extensive surgery.

In order to test this idea, the segment of your jawbone (if this is being removed) and/or fat which is routinely discarded as waste will be sent for testing. Our goal is generate stem cells for replacement of bone from patients suffering from this disease.