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Clinical Studies

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  • Establishment of prostate cancer cell lines using biopsies of early stage prostate cancer patients and research on cancer mechanisms through its genes and proteins Rochester, Minn.

    The purpose of this study aims to establish a total of 30 new primary prostate cancer cell lines using a portion of biopsy tissue from early-stage prostate cancer patients and to collect protein characterization data showing high expression for each cell line. The primary objective is to discover specific genes and proteins that show excessive expression differences in each group of prostate cancer cell lines. The specific genes and proteins obtained here will be used to find customized anticancer candidates for prostate cancer patients in the future. As a final objective, we aim to build a new classification of existing molecular subtypes of prostate cancer based on the existing prostate cancer subtypes of androgen receptor (AR) positive, neuroendocrine, ERG fusion positive and ERG fusion negative, and TP53 mutation.
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