Faculty

Div Dubey, M.B.B.S.

Clinical Studies

Evaluation of human sera and cerebrospinal fluid from patients with autoimmune diseases (with and without autoantibodies) for laboratory based analyses Rochester, Minn.
This study aims to identify serological and other blood biomarkers to aid in identificaiton of diagnosis and mechanistic understanding of autoimmune disorders.
Natural history study of LGI 1 IgG associated autoimmune encephalitis Rochester, Minn.
The purpose of this study is to perform retrospective data collection for a natural history study of LGI1 IgG seropositive patients seen at Mayo Clinic sites or Mayo Clinic health system. Also, to identify new LGI1 IgG seropositive patients seen at Mayo Clinic sites or Mayo Clinic health system through the clinical lab for prospective data collection and evaluation for potential clinical trial enrollment.

A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Phase 2 Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Rozanolixizumab in Adult Study Participants with Leucine-Rich Glioma Inactivated 1 Autoimmune Encephalitis (AIE001) Rochester, Minn., Jacksonville, Fla., Scottsdale/Phoenix, Ariz.
The purpose of the study is to assess the efficacy of rozanolixizumab as measured by seizure freedom, change in cognitive function, use of rescue medication, onset of seizure freedom and to assess safety and tolerability.
Rapid Identification of LGI1 Autoimmune Encephalitis Patients For Enrollment Into A Clinical Trial Rochester, Minn.
The purpose of this study is to expedite patient identification of LGI1-IgG autoimmune encephalitis patients for enrollment in the UCB sponsored phase 2 study evaluating the effectiveness and safety of rozanolixizumab.