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  • Combined Cardiac Rehabilitation and Inspiratory Muscle Training in Heart Failure (IMT+CR for HF) Rochester, Minn.

    We are currently enrolling both healthy volunteers and people who have been diagnosed with heart failure to participate in our research study.  The purpose of this study is to better understand the relationship between exercise, breathing, blood flow and blood pressure.  This study includes two study visits if you are a healthy or heart failure volunteer.    All testing will be performed at our testing center at St. Mary’s Hospital located in Rochester, MN. 

    On the first study visit, the research activities will be discussed and all questions will be answered. Once written consent is provided and the participant is enrolled, lung function and exercise capacity will be measured.

    The second study visit includes two separate breathing muscle workouts (a light and moderate workload) each followed by 10 min of light to moderate cycling exercise. In addition, two breathing tests will also be performed. During this visit, blood is drawn during exercise.

    If you are a patient at Mayo Clinic, who is currently enrolled or will be enrolling in a cardiac rehabilitation exercise program, you will have the option to complete four study visits.  Your first two study visits as described above will be completed at the beginning of cardiac rehabilitation and then we will ask you to return to complete those same two study visits following the completion of your cardiac rehabilitation program.

    Remuneration and parking reimbursement are provided.

  • Exercise Pressor Reflex Pathophysiologic Mechanisms in Human Hypertension Rochester, Minn.

    The purpose of this study is to determine how hypertension impacts blood pressure responses during exercise. 

  • Inspiratory Muscle Dysfunction in Heart Failure: Implications for Exercise Intolerance and Exertional Symptomology Rochester, Minn.

    The purpose of this study is to determine the impact of inspiratory muscle dysfunction on exercise tolerance in patients with heart failure.

  • Inspiratory Muscle Training in Heart Failure With Preserved Ejection Fraction Rochester, Minn.

    The purpose of this study is to determine the impact of inspiratory muscle training on inspiratory muscle blood regulation during exercise in heart failure patients with preserved ejection fraction (HFpEF).

  • Peripheral Mechanisms of Cardiovascular Control in Heart Failure Rochester, Minn.

    The purpose of this study is to determine how heart failure impacts blood pressure responses during exercise. 

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