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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 171-180 of 845 for cardiovascular

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  1. A Study to Assess the Effectiveness and Safety of Rilonacept Treatment in Subjects with Recurrent Pericarditis

    Rochester, MN

  2. A Study of the Effectiveness and Safety of Rivaroxaban on Venous Thromboembolic Risk in Patients Following Hospital Discharge

  3. Saline-Enhanced Radiofrequency Catheter Ablation for the Treatment of Ventricular Tachycardia

  4. A Study of the Long-Term Safety of Tafamidis for Patients with Transthyretin Cardiomyopathy

    Rochester, MN

  5. A Study for Sources of Pulmonary Congestion Associated with Heart Failure

    Rochester, MN

  6. A Study of the Long-Term Safety of Tafamidis in Subjects with Transthyretin Cardiomyopathy

    Scottsdale/Phoenix, AZ

  7. Study and Safety Monitoring of Patients with Symptomatic Transthyretin Cardiomyopathy Who Have Completed the Phase II Study AG10-201

    Rochester, MN

  8. Review of the Safety and Effectiveness of the THERMOCOOL SMARTTOUCH® SF Catheter Evaluated for Treating Symptomatic PersistenT AF (PRECEPT)

  9. Efficacy and Safety of Early Exercise Program After Acute DVT for Prevention of Post Thrombotic Syndrome

    Rochester, MN

  10. Mitral Implantation of TRAnscatheter vaLves

    Rochester, MN

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