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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 341-350 of 841 for cardiovascular

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  1. Guiding Evidence Based Therapy Using Biomarker Intensified Treatment

    Rochester, MN

  2. A Study of Lower Body Negative Pressure for Research and Development on Non-Invasive Monitoring Devices

    Rochester, MN

  3. A Study to Evaluate Effectiveness of 2 Doses of Oral CXA-10 in Pulmonary Arterial Hypertension (PAH)

    Jacksonville, FL

  4. A Study of Subcutaneous ICD Therapy Combined With VT Ablation for the Secondary Prevention of Sudden Cardiac Death

    Rochester, MN

  5. A Study Evaluate the Positive Impact of Canine Therapy on Cardiac Rehab Patient Outcomes

  6. A Study to Evaluate a Novel Technique to Diagnose Carotid Artery Stenosis

    Rochester, MN

  7. ATTR Expanded Access Program (EAP) by Ionis

    Rochester, MN

  8. A Study of Low Intensity Mechanoreflex during Exercise in Healthy Adults

    Rochester, MN

  9. A Study to See if Clinical Cardiac MRI Scanning Can Cause DNA Damage

    Rochester, MN

  10. A Study to Evaluate the Thoracotomy Implant Technique of the HeartWare HVAD System in Patients with Advanced Heart Failure

    Rochester, MN

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