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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 91-100 of 232 for head and neck

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  1. FDG-PET/CT in Assessing the Tumor and Planning Neck Surgery in Patients With Newly Diagnosed H&N Cancer

    Rochester, MN

  2. Post Operative Adjuvant Therapy De-intensification Trial for Human Papillomavirus-related, p16+ Oropharynx Cancer

    Scottsdale/Phoenix, AZ

  3. Development and Implementation of Innovative Auditory Training Methods and Verification of These Training Methods

    Rochester, MN

  4. Integrating Patients and Families into the Clinical and Outcomes Research Process

    Rochester, MN

  5. A Study of Response, Survival, Safety, and Tolerability of Lenvatinib for the Treatment of Anaplastic Thyroid Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  6. Implantation of the HiRes90K™ Advantage Cochlear Implant With HiFocus™ Mid-Scala and Development of a Combined Electric and Acoustic Stimulation Technology in Adults with Partial Deafness

    Rochester, MN

  7. Automatic Periodic Stimulation and Continuous Electromyography (EMG) for Facial Nerve Monitoring During Parotidectomy

    Rochester, MN

  8. Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors

    Rochester, MN

  9. Laryngeal Allograft Transplantation

    Scottsdale/Phoenix, AZ

  10. Prospective Study of Round Window Versus Cochleostomy Approach to CI Surgery

    Rochester, MN

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