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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 61-70 of 183 for lung disease

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  1. Safety Study of Inhaled Saline in Acute Lung Injury

    Rochester, MN

  2. A Study to Evaluate Durvalumab Alone or in Combination With Novel Agents in Subjects With NSCLC

  3. Phase 1b Open-Label Study of PEGPH20 With Pembrolizumab

    Scottsdale/Phoenix, AZ

  4. Neoadjuvant Pembrolizumab

    Rochester, MN

  5. LIPS-B: Lung Injury Prevention Study with Budesonide and Beta

    Jacksonville, FL, Rochester, MN

  6. A Study of Clofazimine for Treating Patients with Drug Resistant Non-Tuberculous Mycobacterial Infections

    Rochester, MN

  7. A Study of the Use of Computer Software for the Detection of Lung Diseases Over Time

    Rochester, MN

  8. Study of Nivolumab Combined With Ipilimumab Versus Pemetrexed and Cisplatin or Carboplatin as First Line Therapy in Unresectable Pleural Mesothelioma Patients

    Rochester, MN

  9. A Study to Analyze Potential Long-term Treatments for Covid-19 Recovery

    Scottsdale/Phoenix, AZ

  10. A Study of APR-246 and Pembrolizumab in Patients with Solid Tumor Malignancies

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

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