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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 13 for otology and neurotology

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  1. Novel Tinnitus Implant System for the Treatment of Chronic Severe Tinnitus

    Rochester, MN

  2. A Study to Evaluate Remote Objective Monitoring

    Rochester, MN

  3. A Study to Evaluate the Use of AR-42 (Histone Deacetylase Inhibitor) in the Treatment of Vestibular Schwannoma and Meningioma

    Rochester, MN

  4. Study of Treating Patients with Vestibular Schwannoma with Aspirin

    Rochester, MN

  5. Implantation of the HiRes90K™ Advantage Cochlear Implant With HiFocus™ Mid-Scala and Development of a Combined Electric and Acoustic Stimulation Technology in Adults with Partial Deafness

    Rochester, MN

  6. Prom Stim

    Rochester, MN

  7. Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy

  8. A Study to Evaluate Cochlear Implant Electrode Impedances as a Function of Level and Charge

    Rochester, MN

  9. A Study to Evaluate Ability of Hearing Aids and Wearable Sensors to Detect Falls

    Rochester, MN

  10. A Study to Evaluate the Otonexus Ultrasound Otoscope

    Rochester, MN

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