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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. Research to Test Whether Doing Exercise Training Helps Lessen or Prevent the Longer-term Symptoms of COVID-19 Infection

    Jacksonville, FL

  2. Myoelectric SoftHand Pro to Improve Prosthetic Function for People With Below-elbow Amputations: A Feasibility Study

    Rochester, MN

  3. A Study to Evaluate RheOx Bronchial Rheoplasty System to Treat Chronic Bronchitis in Adults with COPD

    Jacksonville, FL, Rochester, MN

  4. A Study to Evaluate Immunotherapy for Non-Small Cell Lung Cancer

  5. A Study of Inorganic Nitrite to Amplify the Benefits and Tolerability of Exercise Training in Heart Failure that has Preserved Ejection Fraction

    Rochester, MN, Cannon Falls, MN, La Crosse, WI, Albert Lea, MN, Austin, MN, Red Wing, MN, Mankato, MN

  6. Transforming Non-Invasive Liver Disease Detection by Magnetic Resonance Elastography

    Rochester, MN

  7. A Comparative Effectiveness Study in Heart Transplant Patients of Rejection Surveillance With Cell-free DNA Versus Endomyocardial Biopsy (ACES-EMB)

    Jacksonville, FL

  8. ADAPT Study: Long-term Safety Study of INZ-701 in Patients With ENPP1 Deficiency and ABCC6 Deficiency

    Rochester, MN

  9. Mindful Breathing Awareness Through Pursed-Lip Breathing Training

    Rochester, MN

  10. A Study of Cerebral Perfusion with tDCS in Chronic Hypoperfusion

    Rochester, MN

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